Peripheral Artery Disease Interventions Utilizing the Angiosomal Approach to the Complex Wound

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Peripheral Artery Disease Interventions Utilizing the Angiosomal Approach to the Complex Wound Craig M. Walker, MD, FACC, FACP Chairman, New Cardiovascular Horizons Clinical Professor of Medicine Tulane University School of Medicine New Orleans, LA Clinical Professor of Medicine LSU School of Medicine New Orleans, LA Founder, President, and Medical Director Cardiovascular Institute of the South Houma, LA Clinical Editor Vascular Disease Management Global Vascular Digest

Disclosures No Disclosures

The Angiosome Concept Taylor GI,Palmer JH. Br J Plast Surg 1987;40:113 Taylor and Palmer: 3D anatomic unit of tissue fed by a source artery Adjacent angiosomes bordered by choke vessels (indirect connections among angiosomes) Understanding the angiosome principal allows the interventionalist to perform the procedure that maximizes Ischemic ulceration healing Surgical incision/amputation healing

Anterior Tibial Artery Angiosome Peroneal Artery Angiosome Iida O et al. J Vasc Surg 2012;55:363-70.

Posterior Tibial Artery Angiosomes Iida O et al. J Vasc Surg 2012;55:363-70.

Foot Angiosomes

European Journal of Vascular and Endovascular Surgery Volume 48 Issue 1 p. 88e97 July/2014

Goals of Revascularization Direct Flow to the foot Angiosome Concept (Direct flow to ischemic zone when possible. Indirect perfusion may suffice when excellent collateral vessels present.) Achieve at TcPO2 > 20 mm Hg, ideally > 40 mm Hg SPP > 50 mm Hg ACHIEVE ENOUGH BLOOD FLOW TO THE WOUND TO ACHIEVE HEALING

Angiosome Directed Therapy Patient with a medio-lateral heel non healing ulcer, Absent pedal pulses, PT with faint monophasic flow by Doppler. Tibio-pedal Ultrasound mapping showed patent hibernating PT Access should be antegrade with preparation to obtain PT tibial access Also be prepared to do antegrade/retrograde crossing and treatment

Angiosomes directed therapy 10 weeks later Initial wound Posterior Tibial artery w/ diffuse disease, (a single diseased tibial vessel runoff via Peroneal), Critical heel ulcer With global calcaneal hypoperfusion 14

Angiosomes directed therapy. Initial Angio - right Peroneal and PT. Keep in mind, when you have heel ulcers Look for both calcaneal branches. Medial And lateral

Understanding tibiopedal anatomy gives you the upper hand and additional therapeutic options Interventional wire in the antegrade/retrograde approach during CLI angiosome directed therapy Balloon angioplasty in an antegrade/retrograde angiosome directed therapy 16

Angiosome Directed Therapy

initial 5 months later 5 months post therapy 10 months post therapy A multidisciplinary post-therapy approach is critical to Success. J.A. Mustapha, M.D. 18

Ulcer on the Medial Aspect of the Left Ankle Which Artery is Affected? Adams, GL 2011

Ulcer on the Medial Aspect of the Left Ankle

Posterior Tibial Access What s wrong? Happy?

Ulcer on the Medial Aspect of the Left Ankle Angiogram Endovascular Intervention Adams, GL 2011

lcer on the Medial Aspect of the Left Ankle Post Intervention Adams, GL 2011

lcers on the Lateral Aspect of the Right Lower Leg nd Dorsum of the Foot Which Artery is Affected? Adams, GL 2011

Ulcers on the Lateral Aspect of the Right Lower Leg and Dorsum of the Foot Intervention Angiogram Adams, GL 2011

lcers on the Lateral Aspect of the Right Lower Leg nd Dorsum of the Foot ost-intervention Adams, GL 2011

Ideally which artery should we revascularize?

Advanced Techniques for Limb Salvage Distal and multi-vessel intervention Pedal and Tibial Access CTO Techniques Recanalization via collaterals Pedal Arch recanalization

Challenges of Direct Angiosome Perfusion Long lesions Heavy calcifications Sub-optimal Equipment Limited treatment options Poor long term patency ACHIEVING LIMB SALVAGE PERFUSION IS NOT EASY AND OCCASIONALLY REQUIRES MORE THAN ONE INTERVENTION.

Peripheral Artery Disease Interventions Utilizing the Angiosomal Approach to the Complex Wound Craig M. Walker, MD, FACC, FACP Chairman, New Cardiovascular Horizons Clinical Professor of Medicine Tulane University School of Medicine New Orleans, LA Clinical Professor of Medicine LSU School of Medicine New Orleans, LA Founder, President, and Medical Director Cardiovascular Institute of the South Houma, LA Clinical Editor Vascular Disease Management Global Vascular Digest