North of England Bone and Soft Tissue Tumour Service

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North of England Bone and Soft Tissue Tumour Service Guidelines for rehabilitation after replacement of the proximal femur Proximal femoral replacement surgery is usually carried out as part of treatment for a tumour involving the proximal femur. This surgery is complex and treatment varies according to the needs of the individual. Many patients also undergo chemotherapy and occasionally radiotherapy treatment which can interfere with rehabilitation. The aim of this document is to provide some information about proximal femoral replacement to guide rehabilitation. The needs of patients vary and the application of these guidelines to the treatment of individual patients should be discussed with the clinical team. November 2014 Review November 2017

What is Proximal Femoral Replacement? Proximal femoral replacement is a procedure in which the proximal femur and often the surrounding soft tissues are removed, usually as part of treatment for a primary bone tumour such as osteosarcoma or a secondary bone tumour, such as metastatic breast cancer. Some patients may have replacement of the proximal femur as treatment for failed hip replacement or fracture. The anatomical structures which are removed include a variable amount of the bone itself, and the surrounding muscles. The acetabulum may or may not be replaced. The aim of the surgery is to spare the limb and restore mobility and function. The bone is usually reconstructed with a cemented custom or modular implant. Some children may receive an implant which can be lengthened as they grow. Some implants may be silver coated to reduce the risk of infection. The soft tissues are reconstructed to the implant and to the surrounding soft tissues. Usually the hip abductors and flexors do not work as well as before surgery. This surgery is complex and there are risks. Recognised complications include: Dislocation (higher rates than for routine hip replacement) Deep infection Weakness of the leg (eg foot drop), usually as a result of nerve or muscle resection Thrombosis or embolism Local recurrence of the tumour Loosening of the implant Expected outcome: Can take a year or more to achieve optimal function Abductor weakness leading to a limp is common Independently mobile but may need walking aids Self caring Return to non-impact sports may be possible Muscles affected: Gluteus maximus, minimus and medius, psoas, short external rotators of hip, hip adductors.

Rehabilitation schedule The following is a guide to treatment only. This regime should be tailored according to the individual needs of the patient through discussion with the clinical team. In particular, many patients have chemotherapy after treatment which has a major impact on their ability to rehabilitate. Time period Goals Intervention 0-5 days Optimise tissue healing Ensure pain control Avoid swelling Avoid dislocation Care for pressure areas Avoid respiratory complications Breathing exercises and pressure care Out of bed once drains removed Avoid hip flexion beyond 90 degrees, Use hip abduction brace if appropriate 1-6 weeks Avoid dislocation Increase mobility Protect abductor repair Return to normal living 6-12 weeks Avoid dislocation Increase mobility Return to normal living Wound monitoring with check at 2 weeks Avoid hip flexion beyond 90 degrees, Maintain ROM at knee and ankle Continue use of walking aids and protected weight bearing to protect abductor repair. OT input around return to driving, self care, avoiding dislocation Ensure continuing physiotherapy after discharge Avoid hip flexion beyond 90 degrees, Maintain ROM at knee and ankle Increase weight bearing depending on progress OT input around return to driving, self care, avoiding dislocation Ensure continuing physiotherapy Core stability

>12 weeks Consolidate and improve strength Establish normal gait Establish independence Wean from brace Wean from walking aids if feasible Ensure even weight bearing Balance and proprioception Core stability OT input as appropriate Occupational Therapy Intervention Occupational therapy intervention is important in protecting the hip against dislocation and to enable the patient to gain maximum levels of independence prior to leaving hospital. During the acute hospital admission phase the patient will receive occupational therapy input for: - Hip precautionary education and measurement of safe height popliteal leg length measurement plus 2. - Provision of adaptive equipment to enable adherence to safe height. - Application of abduction brace (if applicable). - Lower limb dressing using small dressing aids to adhere to hip precautions. - Bed, chair and toilet transfers (as appropriate). - Further ADL assessments including bathing and kitchen. - Advice on other functional roles and impact of hip precautions e.g. work, sexual activity. - Advice on and education about relaxation techniques. - Referral to social services for any care package needs. The impact of cancer and adjuvant treatments on rehabilitation A diagnosis of cancer and the treatment that follows have major impacts on many aspects of the lives of patients and their families. Although physical functioning is an important aspect of the survivorship experience for patients with sarcoma, others include psychological health, and the impact on employment and relationships. Anxiety and depression can have a major impact on rehabilitation the setting of achievable goals may be helpful in increasing the feeling of control experienced by patients. Physical rehabilitation after a surgical procedure is just one aspect of maximising outcomes for these patients.

Chemotherapy Multiagent chemotherapy routinely leads to bone marrow toxicity. White cell counts are at their lowest 10-14 days after a cycle of treatment, at which point the patient is at risk of infection. Contact with other patients, particularly those with infections and hydrotherapy should be avoided at this point. Chemotherapy may lead to nausea, vomiting, diarrhoea, loss of appetite, fatigue, lethargy and reduced exercise tolerance. Many patients find it difficult to rehabilitate during chemotherapy treatment Radiotherapy In the short term, radiotherapy leads to redness, soreness and sensitivity of the skin. In the longer term, radiotherapy can lead to fibrosis of soft tissues and loss of movement which can progress for up to two years or more. Physiotherapy during and after radiotherapy treatment may help to prevent this. Heat treatments are contraindicated after radiotherapy. Application of lotions and manual treatments are contraindicated during radiotherapy, but can be used with caution afterwards. Electrical treatment modalities can be used with caution. In the longer term, radiotherapy can lead to weakness of the bone and is associated with a risk of fracture. Lymphoedema is a common side effect of treatment. Sources and further reading Malawar, M and Sugarbaker, P. Musculoskeletal Cancer Surgery: Treatment of Sarcomas and Allied Diseases. Springer 2001. (Available at www.sarcoma.org) Shehadeh, A., El Dahleh, M., Salem, A., Sarhan, Y., Sultan, I., Henshaw, R. M., & Aboulafia, A. J. (2013). Standardization of rehabilitation after limb salvage surgery for sarcomas improves patients outcome. Hematology/oncology and Stem Cell Therapy, 6(3-4), 105 11. doi:10.1016/j.hemonc.2013.09.001 https://www.rnoh.nhs.uk/clinical-services/rehabilitation-guidelines Authors Craig Gerrand, Consultant Orthopaedic Surgeon Emma O Dwyer, Occupational Therapist Peter McClintock, Senior Physiotherapist