Chapter 1. Organ Donation. in Australia and New Zealand

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Chapter 1 Organ Donation in and New Zealand

n and New Zealand donor figures include all donors consented for organ and tissue donation who went to the operating theatre for the purpose of organ or tissue retrieval for transplantation. This is consistent with international reporting (World Health Organisation - Human Organ and Tissue Transplantation. http://www.who.int/ethics/topics/human_transplant/en/). The deceased organ donors per million population (dpmp) figures in rose to 16.9 dpmp in 213, from 15.6 dpmp in 212 and 15.1 dpmp in 211. In New Zealand, the rate decreased to 8.1 dpmp in 213 from 8.6 dpmp in 212 and by 1.9 dpmp since 29. Of the 391 actual deceased organ donors in 213 for, 375 donors had at least one organ retrieved. Of those 375 donors, 362 resulted in at least one organ transplanted. Sixteen actual donors had no organs retrieved. This number has increased over the past five year from six in 29 to sixteen in 213. The reasons these donors had no organs retrieved is a result of twelve donors with medically unsuitable organs for transplantation; one donor was discovered with malignancy and there were no suitable recipients fro three donors. Twelve of the these 16 donors still proceeded to donate eyes and/ or tissue. In New Zealand all 36 actual donors had at least one successfully transplanted. In, there remains variation in organ donation rates between jurisdictions (Figure 1.1). In 213, rates varied from 14 dpmp in New South Wales to 29 dpmp in the Northern Territory. The rate in the ACT was 16 dpmp when the NSW Southern Area Health Service population was excluded, but 1 dpmp when this area was included. Figure 1.1 Number of Actual Deceased Organs Donors** by Retrieval State / Country (X) 29-213 ( ) Donors Per Million Population 29 21 211 212 213 Queensland 47 (11) 49 (11) 67 (15) 78 (17) 77 (17) New South Wales + * 68 (1+) (1*) 87 (12+) (13*) 77 (11+) (11*) 88 (12+) (12*) 12 (14+) (14*) ACT + * 8 (14+) (23*) 1 (17+) (28*) 8 (14+) (22*) 12 (2+) (32*) 6 (1+) (16*) Victoria 65 (12) 98 (18) 17 (19) 92 (16) 11 (19) Tasmania 5 (1) 1 (2) 6 (12) 15 (29) 8 (16) South 33 (21) 31 (19) 35 (21) 29 (18) 34 (2) Northern Territory 2 (9) 2 (9) 4 (17) 8 (34) 7 (29) Western 19 (8) 22 (1) 33 (14) 32 (13) 47 (19) 247 (11.3) 39 (14) 337 (15.1) 354 (15.6) 391 (16.9) New Zealand 43 (1) 41 (9.4) 38 (8.6) 38 (8.6) 36 (8.1) (x) refers to donors retrieved by retrieval State (e.g. Albury-NSW donors retrieved by Victoria) + NSW population excludes residents of the NSW Southern Area Health Service (included in ACT population) * NSW population includes residents of the NSW Southern Area Health Service (excluded from ACT population) Medical services from the ACT service the NSW Southern Area Health Region. Population data - June ABS 311. ** This figure relates to the number of donors for whom the retrieval operation commenced for the purpose of transplantation. It includes donors who may be deemed medically unsuitable at the time of the surgery or after removal of organs. 1 2

Figure 1.2 12 15 9 Number of Actual Deceased Donors n States 1998-213 Figure 1.3 Number 4 75 6 45 3 15 1998 1999 2 21 22 23 24 25 26 27 28 29 21 211 212 213 NSW VIC QLD SA WA TAS NT ACT Number of Actual Deceased Donors Per Million Population n States 29-213 4 3 2 1 3 2 1 29 21 211 212 213 Year QLD NSW* ACT* VIC TAS SA NT WA * NSW population excludes residents of the NSW Southern Area Health Service. * ACT population includes residents of the NSW Southern Area Health Service. 1 3

There has been a steady decline in overall death rates among most ages in over recent years. In many respects, using the number of deaths as the denominator may be a more logical comparator; rates for various jurisdictions using this metric are shown in Figure 1.4 and 1.5. Figure 1.4 Number of Actual Deceased Donors Per 1, Deaths n States 22-212 8 7 6 5 4 3 2 1 22 23 24 25 26 27 28 29 21 211 212 8 7 6 5 4 3 2 1 QLD NSW* ACT* VIC TAS SA NT WA AUS NZ * NSW and ACT values not adjusted for the the NSW Southern Area Health Service, as death data were not available n data on deaths 212 was the latest release at the time of this publication. n Bureau of Statistics - Deaths 333. and Statistics New Zealand Figure 1.5 Donors per 1, Deaths Aged < 75 years 28-212 ( ) is the % Deaths < 75 years as a Proportion of all Deaths* Year QLD NSW ACT VIC TAS SA NT WA AUST NZ 28 47 (38%) 35 (33%) 83 (36%) 58 (33%) 56 (34%) 11 (31%) 4 (74%) 58 (38%) 52 (34%) 28 (38%) 29 46 (39%) 42 (34%) 134 (39%) 55 (33%) 33 (36%) 82 (32%) 28 (77%) 39 (39%) 5 (35%) 39 (38%) 21 47 (39%) 54 (34%) 166 (36%) 86 (32%) 67 (35%) 76 (32%) 28 (75%) 45 (38%) 62 (35%) 38 (38%) 211 65 (38%) 46 (33%) 132 (36%) 91 (32%) 4 (35%) 89 (31%) 57 (75%) 68 (38%) 67 (34%) 34 (37%) 212 74 (37%) 54 (33%) 213 (33%) 84 (31%) 11 (34%) 73 (3%) 13 (76%) 64 (37%) 71 (34%) 34 (37%) * The number of actual donors is compared to the number of deaths that are aged less than 75 years (Figure 1.6) n Bureau of Statistics - Deaths 333. and Statistics New Zealand 1 4

Figure 1.6 represents the rate of organs donated, recipients transplanted and deceased organ donor number over time. Much of the increase in donor numbers has arisen from changes in rates of donors after circulatory death (DCD), demonstrated in Figure 1.7. Figure 1.6 Total Number of Organs, Recipients and Actual Deaceased Organ Donors Per Million Population,, 1998-213 6 5 Actual Donors Recipients Organs Per Million Population 4 3 2 1 1998 1999 2 21 22 23 24 25 26 27 28 29 21 211 212 213 Year Figure 1.7 Organ Donation Pathway 1998-213 35 3 DBD DCD 277 236 24 251 Number 2 194 163 195 183 24 178 215 195 194 179 25 1 69 86 77 86 42 2 1998 1 1 2 1999 2 2 22 21 1 3 24 23 9 25 19 8 26 27 23 28 29 21 211 212 213 1 5

Figure 1.8 Overview Popula on (million) 23.1 Actual Deceased Organ Donors both DBD & DCD included (pmp) 391 (16.9) Kidney Tx Recipients from deceased donors (pmp) 63 (27.2) Liver Tx Recipients from deceased donors (pmp) 252 (1.9) Heart Tx Recipients from deceased donors (pmp) 77 (3.3) Heart Lung Tx Recipients from deceased donors (pmp) 2 (.1) Lung Tx Recipients from deceased donors (pmp) 167 (7.2) Pancreas Tx Recipients from deceased donors (pmp) 33 (1.4) Pancreas Islet Tx Recipients from deceased donors (pmp) 1 () Total number of Transplant Recipients (pmp)^ 1122 (48.5) Total number of Organ Transplants (pmp)* 1177 (5.9) (pmp) per million popula on Figure 1.9 New Zealand Overview Popula on (million) 4.5 Actual Deceased Organ Donors both DBD & DCD included (pmp) 36 (8.1) Kidney Tx Recipients from deceased donors includes all combina ons (pmp) 55 (12.3) Liver Tx Recipients from deceased donors includes all combina ons (pmp) 26 (5.8) Heart Tx Recipients from deceased donors includes all combina ons (pmp) 9 (2) Lung Tx Recipients from deceased donors includes all combina ons (pmp) 18 (4) Total number of Transplant Recipients (pmp)^ 18 (24.2) Total number of Transplant Organs (pmp)* 111 (24.9) (pmp) per million popula on * The total number of transplant organs differs from total number of transplant recipients as each organ, with the excep on of double lung, is counted as a single organ transplant. ^ The total number of recipients include all combina ons of mul organ transplants as a single count of transplanta on. Note: Further informa on on organ transplants can be found in Chapter 5 Organ Data. 1 6

Figure 1.1 Number of Organ Transplants in 213 by State / Country of Donation (pmp) in and New Zealand Organs QLD NSW ACT VIC TAS SA NT WA AUST NZ Kidney 128 167 11 167 15 55 14 88 645^ (27.9) 58 *(13.) Liver 45 74 7 57 7 24 5 33 252 + (1.9) 26 ++ (5.8) Heart 15 21 2 17 1 1 11 77 (3.3) 9 (2.) Heart/Lung 2 2 (.1) (.) Lung 36 4 3 47 4 12 3 22 167 # (7.2) 18 (4.) Pancreas 2 13 2 6 1 5 4 33 (1.4) (.) Pancreas Islets 1 1 (.) (.) Intestine (.) (.) Total 226 317 25 294 27 17 23 158 1177 (5.9) 111 (24.9) ^ includes 615 single kidneys, 9 double adult kidneys and 6 enbloc kidneys in * includes 52 single kidneys, 2 double adult kidneys and 1 en-bloc kidneys in New Zealand + includes 27 whole liver, 38 split liver and 7 cut down liver in ++ includes 21 whole liver, 4 spilt liver and 1 cut down liver in New Zealand # includes 162 double lung and 5 single lung in Figure 1.11 The number of organ transplants per donor is calculated by the number of organs retrieved from actual donors for the purpose of transplantation divided by the number of actual donors. 5 4 Number of Transplant Organs per Donor Number of Organ Transplants per Donor 24 -- 213 The number of organ transplants per donor each year from 24-213 in and New Zealand is shown in Figure 1.11. The number of transplant organs per donor across ranged from 4.2 organ transplants in the ACT to 2.6 in Victoria. Mean 3 2 1 24 25 26 27 28 29 21 211 212 213 Year New Zealand 1 7

Figure 1.12 shows the organ-specific transplant rates for over the period 1998-213 (i.e. organ transplants per million population). Figure 1.13 shows the corresponding rates for donation after circulatory death. Transplantation of organs from DCD has contributed to a significant increase in the rate of kidney transplantation. Figure 1.12 3 25 Kidney Liver Heart Heart-Lung Lung Pancreas Pancreas Islets Organ Transplants 1998-213 Per Million Population, Intestine Per Million Population 2 15 1 5 1998 1999 2 21 22 23 24 25 26 27 28 29 21 211 212 213 Year Figure 1.13 7 6 Kidney Lung Organ Transplants from DCD Donors, 1998-213 Per Million Population, Liver Pancreas Per Million Population 5 4 3 2 1 1998 1999 2 21 22 23 24 25 26 27 28 29 21 211 212 213 Year 1 8

The number of deceased donors previously reported in this chapter are based on the State/Territory and country location in which the donor died, Figure 1.14 details the number and proportion of donors by remoteness category. Overseas refers to donors who usually reside outside of and New Zealand. The ABS standardised remoteness structure known as the Accessibility/Remoteness Index of (ARIA) is used. (http://www.abs.gov.au/websitedbs/d331114.nsf/home/remoteness+structure#anchor2b). Supplement 1 shows a more detailed breakdown of the number of donors by retrieval hospital. Figure 1.14 Location of Deceased Donors 29-213 ARIA QLD NSW ACT VIC TAS SA NT WA AUST Major Ci es of Inner Regional Outer Regional Remote Very Remote 172 (54%) 36 (73%) 29 (66%) 335 (71%) 1 (2%) 11 (68%) 2 (9%) 13 (68%) 158 (65%) 86 (27%) 87 (21%) 11 (25%) 114 (24%) 24 (56%) 24 (15%) 1 (4%) 3 (2%) 377 (23%) 49 (15%) 19 (5%) 3 (7%) 15 (3%) 15 (35%) 22 (14%) 13 (57%) 8 (5%) 144 (9%) 4 (1%) 2 (<1%) (%) (%) 2 (5%) 3 (2%) 4 (17%) 7 (5%) 22 (1%) 2 (1%) (%) (%) (%) (%) 2 (1%) 3 (13%) 3 (2%) 1 (1%) Overseas 4 (1%) 5 (1%) 1 (2%) 5 (1%) 1 (2%) 1 (1%) (%) 1 (1%) 18 (1%) Total 317 419 44 469 43 162 23 152 1629 In the last five years (29-213) there have been 18 deceased donors who were visitors to. In 213, there were three donors from overseas in, two donated from New South Wales and one from Western. There were no overseas donors in New Zealand in 213. The Registry does not consider organs donated in and transplanted in New Zealand as an overseas donor for New Zealand, nor organs donated in New Zealand and transplanted in as an overseas donor for. 1 9

Suggested Cita on: ANZOD Registry, 214 Annual Report, Chapter 1: Organ Dona on. and New Zealand Dialysis and Transplant Registry, Adelaide,. 214. Available at: h p://www.anzdata.org.au C-\ Royal Adelaide Hospital East Wing 9th Floor North Terrace, Adelaide South www.anzdata.org.au 214