Importance of daily portal imaging for Head and Neck IMRT treatments. Luciant Wolfsberger Brigham & Women s Hospital

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Importance of daily portal imaging for Head and Neck IMRT treatments Luciant Wolfsberger Brigham & Women s Hospital

Overview Head and Neck IMRT treatments Immobilization for Head and Neck IMRT treatments Daily Portal Imaging Retrospective study of Isocentric shifts and Superclavicular shifts Results Other positioning issues Future immobilization devices

3D-CRT IMRT 70Gy 70Gy Tumor volume expansion 1cm Tumor volume expansion 5mm

Head and Neck Immobilization Indexed base-plate Acuform patientspecific headrest

Head and Neck Immobilization Thermoplastic head-neck-shoulder mask (S-Type,Medtec)

Location of Head and Neck tumor volumes C2

Image-guided head and neck radiation therapy(1) Portal Imaging Device Portal Image

Image-guided head and neck radiation therapy(1) Therapists compare daily images with DRRs Portal Image DRR

Image-guided head and neck radiation therapy (1) Digital portal images taken daily

Daily Imaging Dose Need to include imaging dose (1.5-2Gy) in evaluation of final plan

Imaging Imaging dose included in IMRT optimization as a base plan IMRT Final dose distribution

Image-guided head and neck radiation therapy (2) Shifts Happen! ISO SCV

Isocentric Shifts At Isocenter, shifts are made using 3mm action level Patient repositioned in mask if considered necessary Patient repositioning noted by therapists in the treatment chart

Isocentric Shifts Vertical Longitudinal (head towards gantry) Lateral

Supraclavicular Shifts At the Supraclavicular (SCV) level, portal images are repeated if shoulders are shifted SCV shifts start to appear for the later part of the patients treatment. Shifts are made only in a lateral direction Whole process adds around 3min to treatment time

8cm below ISO Supraclavicular shifts

Retrospective study of isocenter and supraclavicular shifts (1) Review of 15 patients for isocentric shifts Use couch coordinates from IMPAC record and verify Difference between couch coordinates for imaging and treatment gives magnitude and direction of shift Vert Lat Long Port Rt lat 270 17.5 999.2 77.8 Port AP 0 17.0 999.2 77.8 Fixed RPO 220 17.0 999.5 77.8

Shifts at isocenter: Results Isocenter discrepancies of 3mm or smaller in any direction were recorded for a median of 92.5% of the fractions (range: 71.4-100%) Isocenter shift larger than 5mm were recorded twice: 2 patients, 1 fraction each (0.38% of all of the fractions)

Retrospective study of isocenter and supraclavicular shifts (2) Review of 10 patients for supraclavicular shifts Size of SCV (8cm below iso) repositioning evaluated retrospectively by experienced therapist

How often is a SCV shift needed? 60 50 Range: 3-34% Patients (%) 40 30 20 10 0 0-10 10-20 20-30 30-40 % fractions for which shoulder shifted noted Patients were repositioned in the immobilization mask before treatment for a median of 14% of the fractions

Size of SCV shifts 35 30 Frequency (%) 25 20 15 10 5 0 0 0.3 0.5 0.7 0.9 1.1 1.3 Size of shoulder shift (cm) 59% of the SCV shifts were less than 5mm 30% of the SCV shifts were 1cm or larger

Direction of SCV shifts Shifts (for given patient) are always in same direction 50% of patients had all shoulder shifts in left direction 50% of patients had all shoulder shifts in right direction

Dosimetric impact of SCV shifts For IMRT plans (5mm margins), a 1cm lateral shift in the SCV region can reduce the dose to the target volume by as much as 25% Daily imaging is therefore important to prevent reduced doses to inferior target volumes

Other positioning issues Supraclavicular positioning issues dominate Occasional jaw and neck positioning issues, caught by daily portal imaging Usually because patient pushed into mask differently

Summary With current immobilization, daily isocenter positioning is excellent Supraclavicular positioning is more variable Important to evaluate daily portal images for entire treatment volume not just isocenter Daily imaging is essential for accurate delivery of IMRT Currently evaluating different immobilization techniques

Future Immobilization Devices Head-neck-shoulder cast (Medtec Vaculoc) Eliminates the use of a custom head rest