Current Topics in Breast Cancer Symposium

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Current Topics in Breast Cancer Symposium Friday, October 6, 2017 Sheraton Station Square Hotel Pittsburgh, PA Sponsored by Allegheny General Hospital In collaboration with Cancer Institute

Conference Overview This symposium will cover area of recent advances and controversies related to breast cancer screening and detection, surgical, radiation and medical breast cancer care. Following its presentation participants should be able to identify new imaging technology for screening and detection, improved treatment methods addressing local and systemic therapies, advances and concerns in a patient s quality of life, and the personalized approach to care using molecular and genetic tools. Who Should Attend This course is designed for physicians, nurses and other health care professionals practicing in the areas of Surgical, Medical, Radiation Oncology, Pathology, and General Surgery, recommended for any practitioner caring for women. At the conclusion of this course, participants should be able to: Identify the existing standard of care treatments for breast cancer Become familiar with evolving novel systemic treatments utilizing molecular and immunotherapy targeting of breast cancer Understand the utility/importance of molecular assays Describe the importance of clinical trials in the advancement of breast care treatments

Conference Directors Thomas B. Julian, MD, FACS Professor of Surgery, Drexel University College of Medicine Director, Division of Breast Surgical Oncology Josh Lauring, MD, PhD Assistant Professor of Oncology Antonio C. Wolff, MD, FACP, FASCO Professor of Oncology Breast & Ovarian Cancer Program, Keynote Speaker Norman Wolmark, MD, FACS Professor of Surgery, Drexel University College of Medicine Chairman, NRG Oncology Chairman, National Surgical Adjuvant Breast and Bowel Project Foundation (NSABP) Division of Breast Surgical Oncology Faculty Roisin Connolly, MD Assistant Professor of Oncology Leisha A. Emens, MD, PhD Associate Professor of Oncology Carol Glock, MEd President, Glock Foundation Larisa Greenberg, MD Division of Hematology and Oncology Susan Harvey, MD Director, Johns Hopkins Breast Imaging Section The Johns Hopkins Comprehensive Cancer Center Christie Hilton, DO Division of Hematology and Oncology Thomas B. Julian, MD, FACS Professor of Surgery, Drexel University College of Medicine Director, Division of Breast Surgical Oncology Josh Lauring, MD, PhD Assistant Professor of Oncology Maureen May, MS Genetic Counselor David S. Parda, MD, FACP Professor and System Chair Department of Oncology/Cancer Institute /IRB Ben Park, MD, PhD Associate Director, Hematology/Oncology Fellowship Training Jane Raymond, MD Division of Hematology and Oncology Karen Smith, MD, MPH Assistant Professor of Oncology Mark Trombetta, MD, FACR Professor of Radiation Oncology Drexel University College of Medicine Breast and Brachytherapy Program Leader Division of Radiation Oncology Allegheny Health Network Cancer Institute Jean Wright, MD Director of Breast Cancer Program Department of Radiation Oncology and Molecular Radiation Sciences Moderators Diane Buchbarker, MD Division of Hematology and Oncology Lisa Jacobs, MD Associate Professor of Surgery Vered Stearns, MD Breast Cancer Research Chair in Oncology Co-Director, Breast and Ovarian Cancer Program Antonio C. Wolff, MD, FACP, FASCO Professor of Oncology Breast & Ovarian Cancer Program,

Conference Agenda 7:00 a.m. Registration/Breakfast/Exhibits 7:55 a.m. Introduction Thomas Julian, MD 8:00 a.m. AHN/Highmark - Johns Hopkins Collaboration Overview David Parda, MD Local Therapy - Moderator: Lisa Jacobs, MD 8:05 a.m. Breast MRI high-risk screening and abbreviated protocols Susan Harvey, MD 8:20 a.m. Surgical controversies - Axillary staging - Completed & ongoing studies Thomas Julian, MD 8:35 a.m. Maximizing tumor control and minimizing toxicities Jean Wright, MD 8:50 a.m. Radiation therapy for inbreast tumor recurrence and metastatic disease Mark Trombetta, MD 9:05 a.m. Q & A 9:15 a.m. Break Quality of Life - Moderator: Diane Buchbarker, MD 9:30 a.m. Breast cancer in very young women: Reproductive health considerations Karen Smith, MD 9:45 a.m. Cognitive function of women receiving breast cancer therapy Larisa Greenberg, MD 10:00 a.m. The voice of the survivor Carol Glock, MEd 10:15 a.m. Q & A 10:25 a.m. Break Personalized Medicine - Moderator: Antonio Wolff, MD 10:40 a.m. Personalizing management of affected moderate-penetrance gene mutation carriers Maureen May, MS 10:55 a.m. Use of tumor gene sequencing for clinical management Josh Lauring, MD 11:10 a.m. Circulating plasma tumor DNA as biomarkers for breast cancer therapy Ben Park, MD, PhD 11:25 a.m. Q & A 11:35 a.m. Lunch 12:40 p.m. Keynote - The contribution of NSABP clinical trials to the management of early breast cancer Norman Wolmark, MD 1:00 p.m. Q & A Systemic Therapy - Moderator: Vered Stearns, MD 1:10 p.m. Emerging treatments for triple negative breast cancer Christie Hilton, DO 1:25 p.m. Hot topics in ER+ breast cancer Jane Raymond, MD 1:40 p.m. Escallation and de-escallation of HER2 therapy Roisin Connolly, MD 1:55 p.m. Immunotherapy treatment of breast cancer Leisha Emens, MD 2:10 p.m. Q & A 2:20 p.m. Closing Remarks Thomas Julian, MD, Antonio Wolff, MD 2:30 p.m. Adjournment

Accreditation Allegheny General Hospital is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. Credit Designation Statement Allegheny General Hospital designates this live activity for a maximum of 5.0 AMA PRA Category 1 Credits TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Participants claiming CME credit from this activity may submit the credit hours to the American Osteopathic Association for Category 2 credit. Nurses West Penn Hospital is an approved provider of continuing nursing education by the Pennsylvania State Nurses Association, an accredited approver by the American Nurses Credentialing Center s Commission on Accreditation. Pharmacists Allegheny General Hospital Department of Pharmacy Services is accredited by the Accreditation Council on Pharmacy Education as a provider of continuing pharmacy education. Total credits to be determined. Other Credit American Academy of Nurse Practitioners (AANP) accepts AMA PRA Category 1 Credits TM from organizations accredited by the ACCME. American Academy of Physician Assistants (AAPA) accepts certificates of participation for educational activities certified for AMA PRA Category 1 Credits TM from organizations accredited by the ACCME. Allegheny General Hospital has approved this activity for 5.0 contact hours for non-physicians.

Hotel Accommodations Overnight accommodations at the Sheraton Station Square Hotel can be made by calling (412) 261-2000. Please be sure to mention AHN/Johns Hopkins Breast Cancer Conference to receive the discounted rate. Refund Policies A refund of the registration fee, less a $10.00 processing fee, will be made when a written request or a telephone request followed by a written confirmation is received prior to September 22, 2017. After this date, refunds will not be made. Fees will not be refunded for failure to attend. The sponsors of this conference reserve the right to cancel or postpone any conference because of unforeseen circumstances or insufficient enrollment. In the event of such cancellation, full tuition will be refunded. Registration Information The registration fee includes the course materials, continental breakfast, lunch and break refreshments. Fee: $90 Physicians $45 RNs, and Other Health Care Providers $25 Offsite Webcast Attendee (limited to first 25 registrants) CE for Physicians only Fee Waived for Fellows and Residents DEADLINE: September 22, 2017 (Registrations will be taken after the deadline date on a space-available basis.) TO REGISTER: To register online, please go to www.aghcme.org. To register by mail or fax, complete the registration form and return it with the registration fee or fax to: Continuing Medical Education Allegheny General Hospital 320 East North Avenue 15212-4772 Fax (412) 359-8218 The preferred method of payment is by VISA, MasterCard, American Express or Discover; however checks will be accepted made payable to Allegheny General Hospital. Additional Information For additional information concerning the conference, please contact the Continuing Medical Education office by e-mail at rachel.phillips@ahn.org, by telephone at (412) 359-4952.

Current Topics in Breast Cancer Symposium Friday, October 6, 2017 Registration for Current Topics in Breast Cancer Symposium is required. Please complete this registration form and return it with your payment no later than September 22, 2017. $90 $45 $25 Physicians RNs, and Other Health Care Providers Offsite Webcast Attendee (limited to first 25 registrants) Fee Waived for Fellows and Residents Name/Degree Affiliation (print name and degree, if applicable, as you wish it to appear on badge) Home or Business Address (including department): (where you prefer mail to be sent) City State ZIP Day Telephone ( ) FAX# ( ) Email Method of Payment: Credit Card Check Credit Card Type: Visa MasterCard American Express Discover Total Amount Credit Card # Exp. Date Name on Card Signature* * By signing this form, I authorize Allegheny General Hospital to charge my credit card for the above amount. My signature also indicates that I will not dispute this charge in the future through my credit card company. If you require assistance with hearing, vision, or mobility to make this conference accessible to you, please check this box and contact the CME office at (412) 359-4952 at least two weeks prior to the conference date.

Continuing Medical Education Allegheny General Hospital 320 East North Avenue 15212-4772 www.aghcme.org Non-Profit Organization U.S. Postage PAID Pittsburgh, PA Permit No. 2885