Urodynamics Assessment & Urotherapy in Children

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Urodynamics Assessment & Urotherapy in Children APN Ng Wai Hing Department of Surgery QEH

Nursing Management in Children with Nocturnal Enuresis Assessment Investigations Urotherapy Program Support

Urodynamic Study Cystometry (CMG) Become synonymous with pressure / flow studies (cystometry or video cystometry)

What is Urodynamics Assessment? Dynamic functional study of the lower urinary tract

Urodynamic Study Comprise of a series of test Diagnostic investigations for patients with urinary incontinence or bothersome LUTS during bladder filling or voiding Identify causes of urine storage & voiding dysfunction

Aims of Urodynamics Studies To reproduce patient s symptoms To correlate patient s symptoms with the underlying urodynamic findings To define detrusor & urethral function during both filling & voiding To establish a precise diagnosis

Types of Assessment Non-invasive History taking Frequency-volume chart (FVC) / Bladder diary Uroflowmetry Bladder scanning

Types of Assessment Invasive Cystometrogram (CMG) Video cystometrogram Ambulatory urodynamics Electromyogram (EMG)

Assessment History Taking Developmental milestone Medical, e.g. organic lesion, operation Urinary function Bowel habit Diet habit Behavioral / Emotional problems Medication Family history / problems

Assessment Physical Examination Body weight / height Urinalysis & urine culture Abdomen palpation Inspection of LS Spine Neurological assessment Genitalia

FV Chart / Bladder Diary Recording fluid intake & urine output per 24 hrs No. of voiding & voided volume Distribution of voiding between daytime & nighttime Episodes of urgency / leakage / incontinence

Bladder Diary Urinary frequency - Normal 4-7 times per day Voided volume - Expected volume: (Age + 1) x 30ml - Range: 65%-150% of expected volume

Investigations KUB XR Spine USG Urinary tract Uroflowmetry Bladder scan Urodynamic study +/- MRI Spine

Uroflowmetry A non-invasive test used to measure pattern, rate & quality of urine flow

Normal Uroflow Pattern Bell Shape

Abnormal Uroflow Pattern Tower Plateau Staccato Interrupted

Uroflow Rate Maximum flow rate (Qmax): - square root of voided volume - Assess bladder outflow - Peak level 2 sec Average flow rate (Qave): - 50 85% of Qmax

Bladder Scanning A non-invasive portable USG instrument that measures post void residual (PVR)

Bladder Scanning Normal PVR 20ml or <10% EBC (ICCS, 2006) Normal PVR (ICCS, 2014) For children 4-6 yo - Single PVR < 30ml or < 21% EBC - Repetitive PVR 20ml or < 10% EBC For children 7-12 yo - Single PVR < 20ml or < 15% EBC - Repetitive PVR 10ml or < 6% EBC

Pressure / Flow Cystometry Subtraction Cystometry (CMG) Videocystometry (VCMG) Ambulatory urodynamics

Cystometry (CMG) Interpreted findings with comprehensive history & examination An objective functional test of bladder & urethral function Provides valuable information regarding storing & emptying functions of bladder

Indications Neurogenic bladder dysfunction e.g. Myelomeningocele, occult spinal dysraphism, sacral agenesis Non-neurogenic e.g. epispadias / exstrophy complex, posterior valves, incontinence, overactive bladder Voiding dysfunction associated with significant bladder hypertrophy, VUR or upper urinary tract damage, or detrusor sphincter dyssynergia

Measurements via Cystometry Bladder capacity Bladder sensation Bladder compliance ( V / Pdet) Detrusor stability

Phases of Cystometry

Pressure Parameters of Cystometry P ves : Intravesical pressure P abd : Intra-abdominal pressure P des : Detrusor pressure (P ves - P abd )

Electromyogram (EMG) To assess the synergy between the bladder & urethral sphincter mechanism during voiding Types: - EMG surface patch electrodes placed on pelvic floor - Fine needle electrodes placed directly into perurethral striated sphincter to diagnose neuropathy

Conventional CMG

Wireless / Ambulatory UD Signals transmission from pressure transducer to computer via Bluetooth connection Conventional fill Natural fill

Wireless / Ambulatory UD Child-friendly environment Anxiety Allows natural behavior of the child and bladder

Ambulatory UD Natural Fill Physiological Fill Hydration by - NS infusion through IV line @ 10-20 ml/kg/hr over 1 hour - Drinking fluid

Ambulatory UD Conventional Fill Use artificial filling into bladder NS infusion through suprapubic catheter @ 5% of expected bladder capacity/min

CMG Result

Urotherapy Non-Surgical Non-pharmacological Cognitive, Behavioral, Physical Therapy Individualized Treatment Plan

Urotherapy Program Main goal To normalize bladder function by active cooperation of the child & parents (Lane et al, 2002) To achieve social continence for these children To boost their self-esteem & morale To improve their quality of life

Strategies of Urotherapy Program Education / counseling / support Behavioural Modification Motivational Therapy Enuresis Alarm Bowel Management Program Biofeedback Therapy

Parents attitude Be considerate & patience Reward & encouragement

Education Anatomy & Physiology Explain on micturation mechanism Involve children: age appropriate approach Aids with appropriate toys, diagrams, x-rays, pamphlets Identify the problem, severity, underlying cause

Behavioral Modifications Dietary modification Voiding strategies Proper voiding posture

Behavioral Modification (1): Dietary Modification Adequate fluid intake Daily intake: < 10kg child: 100ml/kg 10kg child : ~ 1000ml 20kg child: ~ 1500ml

Behavioral Modification (1): Dietary Modification Scheduled drinking routine Avoid fluid intake 2 hours before sleep Avoid & black-list irritant fluids / food e.g. caffeine, dairy, citrus, artificial sweeteners, sugars

Behavioral Modification (1): Dietary Modification High fiber diet Daily requirement of fiber = (age + 5) grams Well-balanced meals and snacks Fast foods & junk foods Chocolate

Behavioral Modification (2): Voiding Strategies Timed voiding - Q2-3H, - Before bed time - Alarms / watches DON T hold the voiding & void at the last moment

Behavioral Modification (2): Voiding Strategies Double voiding - Delayed second void - For improved emptying

Behavioral Modification (2): Voiding Strategies Urination with relaxation - Sigh, count or sing during urination - For proper perineal muscle relaxation

Behavioral Modification (3): Proper Voiding Posture Put underwear and pants all down to ankles Proper straddling, NO tight legged Reverse seating if necessary Lean forward Suitable toilet seat size Foot rest

Motivational Therapy Rewards - Not for dry bed only Star chart Reassurance & positive reinforcement

Star Chart

Star Chart

月份 : 一二三四五六日

月份 : 一二三四五六日

Motivational Therapy Take responsibility to change bed linen

Enuresis (Bedwetting) Alarm Bedside alarm Miniature body worn alarm

Enuresis (Bedwetting) Alarm Used as 1 st line treatment Detect wetness (1 st drop of urine) & sound alarm Conditioning: In response to a full bladder & contract pelvic floor muscles noctural bladder reservoir function

Enuresis (Bedwetting) Alarm Motivated child & parents Trial & early follow-up Effectiveness - Success for 14 consecutive dry nights Treatment for 2-3 months Vibrating alarm for hearing impairment child

Bowel Management Program Fecal disimpaction Dietary advice Bowel habit

Enema Microlax Fleet enema Saline solution

Fleet Enema 3-6ml / kg / dose No more than 1 tube per day Alert: Phosphate intoxication, Hyperphosphataemia, Use caution in renal impaired patient

Ideal Position for Fecal Disimpaction Buttocks-up& Head-down

Dietary Advice High fiber diet Daily requirement of fiber = (age + 5) grams Fruit juice instead of soft drinks Drink more fluids, esp. water Well-balanced meals and snacks Fast foods & junk foods Drinks with caffeine, e.g. cola drinks & tea Chocolate

Toilet Training AIM Regular bowel habit Prevent rectal over distension children s awareness of the sensation of rectal filling Help children accept responsibility & needs for their actions

Toilet Training Start from age 2-3 Sit on the toilet after meal / early morning Comfortable toilet environment Proper posture for defecation DON T ignore urge sensation NO rush!! (enough time: 15 20 mins) Give reward when defecation in the toilet

Proper posture for defecation Back straight Lean forward Knees higher than hips Bulge out abdomen Suitable toilet seat size Foot rest (to flatten the anorectal angle & aid in stool passage)

Biofeedback Provides visual or auditory information to patient regarding physiologic event For dysfunctional voiding / DSD

Biofeedback bird Biofeedback sea star

Bristol Stool Form Scale

Hair / Birth Mark Sacral Dimple