ESO-ASCO MASTERCLASS IN CLINICAL ONCOLOGY November 2018 Yerevan, Armenia MASTERCLASS

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ESO-ASCO MASTERCLASS IN CLINICAL ONCOLOGY 10-13 November 2018 Yerevan, Armenia Chairs: G. Curigliano, IT F. Peccatori, IT Host Chair: G. Tamamyan, AM Held in collaboration with MASTERCLASS

AIMS AND OBJECTIVES This clinically oriented educational programme is designed for medical, surgical and radiation oncologists who wish to improve their skills in multidisciplinary care management. The programme will expose participants to a full spectrum of issues in clinical oncology and practice-orientated training focusing on breast, lung, gastrointestinal, gynaecological and prostate cancers and furthermore includes Professional Development topics. Experts will deliver state-of-the-art lectures on specific cancers followed by multidisciplinary tumour board discussions. Faculty members and participants will discuss aspects of medical, surgical, and radiation therapeutic options and how they can be used together for optimal patient outcomes. TEACHING FORMAT The course offers plenary lectures regarding state-of-the-art clinical evaluation and treatments according to current clinical guidelines with specific attention to the educational needs of the region. These clinical sessions are complemented by multidisciplinary tumour board discussions. Cases are submitted and presented by course participants. Additional time will be allocated for participants to deliver case presentations within small groups and receive feedback. All participants will reside at the course venue and participation is compulsory throughout the course. The Masterclass will be entirely in English and at least an intermediate level of English is necessary for admission. THE MASTERCLASS IS: Full immersion Clinically-oriented Multidisciplinary An international faculty of top experts delivering lectures focusing on breast, lung, gastrointestinal, gynaecological and prostate cancers. PARTICIPANT S PROFILE OF THE MASTERCLASS CANDIDATE Age between 25 and 40 years At least 2-3 years experience in clinical oncology (medical oncology, radiation oncology, surgical oncology) Involvement in scientific activities (desirable) At least an intermediate level of English language (simple scientific discussion in English)

FACULTY (as of January 2018) D. Arnold, CUF Hospitals Cancer Center, Lisbon, PT A. Artinyan, Baylor College of Medicine, US A. Avagyan, Yerevan State Medical University, AM A. Avetisyan, National Oncology Center, AM V. Badeyan, National Oncology Center and Yerevan State Medical University, AM S. Bardakchyan, Yerevan State Medical University, AM R. Camacho, IAEA Programme of Action for Cancer Therapy (PACT), Palma de Mallorca, ES F. Cappuzzo, Istituto Toscano Tumori, Livorno, IT A. Costa, European School of Oncology, Milan, IT G. Curigliano, University of Milano, European Institute of Oncology, Milan, IT L. Davtyan, Wigmore Clinic, AM F. De Braud, University of Milano, Fondazione IRCCS Istituto Nazionale Tumori, Milan, IT F. Geara, American University of Beirut, LB L. Harutyunyan, Yerevan State Medical University, AM A. Heidenreich, Universitätsklinikum Köln, DE M. Hovhannisyan, Yerevan State Medical University, AM Y. Janjigian, Memorial Sloan Kettering Cancer Center, US B. Jereczek, European Institute of Oncology, Milan, IT N. Karamyan, National Oncology Center and Yerevan State Medial University, AM P. Khachatryan, Yerevan State Medical University and Histogen Center, AM M. Kostanyan, National Oncology Center and Yerevan State Medical University, AM N. Matinyan, MIBS Medical Center, AM A. Mkhitaryan, Histogen Center, AM V.T. Minasyan, Yerevan State Medical University and Armenian-American Wellness Center, AM O. Pagani, Oncology Institute of Southern Switzerland (IOSI), Bellizona, CH F. Peccatori, European School of Oncology, Milan, IT M. Raza Mirza, Copenhagen University Hospital, DK L. Safaryan, Yerevan State Medical University, AM T. Saghatelyan, National Oncology Center and Yerevan State Medical University, AM M. Sahakyan, Yerevan State Medical University, AM J. Sehouli, Charité Medical University, Berlin, DE U. Schmidt-Straßburger, Universitätsklinikum Ulm, DE G. Tamamyan, Yerevan State Medical University, AM A. Vaporciyan, University of Texas MD Anderson Cancer Center, US H. Vardevanyan, Armenian-American Wellness Center, AM D. Zohrabyan, Yerevan State Medical University, AM

PROGRAMME Friday, 9 November Participants arrivals and registration 19:00 Welcome Dinner Programme: 20:00 Welcoming remarks (Armenian Association of Hematology & Oncology) 20:05 Welcoming remarks (European School of Oncology) 20:15 Welcoming remarks (American Society Clinical Oncology) 20:25 Welcoming remarks (Yerevan State Medical University) 20:30 Welcoming remarks (National Oncology Center of Armenia) 20:35 Opening lecture: Global oncology Current challenges and opportunities U. Schmidt-Strassburger, DE 21:00 Cancer in the Caucasus region M. Hovhannisyan, AM 21:20 Closing remarks Saturday, 10 November CLINICAL SESSION - BREAST CANCER Chairs: Alberto Costa, IT M. Kostanyan, AM 8:30 Biology of breast cancer & impact on treatment options/outcomes A. Mkhitaryan, AM 9:00 Current surgical management of breast cancer A. Costa, IT 9:30 Adjuvant therapy in breast cancer management G. Curigliano, IT 10:00 Principles of breast radiation oncology B. Jereczek, IT 10:30 Coffee break 11:00 Systemic treatment of IV stage breast cancer: the ABC4 guidelines 11:30 Tumor board discussion of breast cancer cases (3 cases) Faculty and local tutors: A. Avetisyan, AM L. Safaryan, AM - H. Vardevanyan, AM T. Saghatelyan, AM O. Pagani, CH 12:30 Lunch break

PROFESSIONAL DEVELOPMENT SESSION I Chair: G. Tamamyan, AM 13:30 ESMO-ASCO Global Curriculum U. Schmidt-Strassburger, DE 13:50 Elements of an excellent scientific presentation Skills of effective moderators - How to give effective feedback G. Curigliano, IT 14:20 Introduce clinical case exercise G. Tamamyan, AM 14:30 Coffee break 15:00- Breakout Groups: 17:00 Participants Clinical Case Discussions (Cases discussion in three groups) Sunday, 11 November CLINICAL SESSION - LUNG CANCER Chair: L. Safaryan, AM 8:30 Surgery of NSCLC A. Vaporciyan, US 8:50 Neo-adjuvant and adjuvant treatment of NSCLC F. Cappuzzo, IT 9:20 Radiation therapy in the treatment of NSCLC B. Jereczek, IT 9:40 Coffee break 10:10 Treatment of IV stage NSCLC with special focus on targeted therapies F. De Braud, IT 10:35 Immunotherapy on metastatic NSCLC F. De Braud, IT 11:00 Therapy of SCLC F. Cappuzzo, IT 12:00 Tumor board discussion of lung cancer cases (3 cases) Faculty and local tutors: L. Harutyunyan, AM N. Karamyan, AM - P. Khachatryan, AM M. Kostanyan, AM - H. Vardevanyan, AM 13:00 Lunch break 14:00 Breakout Groups: Participants clinical case discussions (Cases discussion in three groups) 16:00 Spotlight lecture: Challenges and opportunities in clinical research G. Curigliano, IT

Monday, 12 November CLINICAL SESSION - GASTROINTESTINAL CANCERS Chairs: D. Arnold, PT L. Harutyunyan, AM 8:30 Surgery of esophageal and gastric cancer A. Vaporciyan, US 9:00 Neoadjuvant and adjuvant treatment of gastric and esophageal cancer D. Arnold, PT 9:30 Treatment of IV stage gastric cancer D. Arnold, PT 10:00 Coffee break 10:30 Neoadjuvant and adjuvant treatment of colorectal cancer Y. Janjigian, US 11:00 Treatment of IV stage colon cancer - systemic treatment Y. Janjigian, US 11:30 Surgical treatment of colorectal and anal cancer A. Artinyan, US 12:00 Radiation therapy of rectal and anal cancer F. Geara, LB 12:30 Lunch break 14:30 Tumor board discussion of GI cancer cases (3 cases) Faculty and local tutors: A. Avagyan, AM M. Sahakyan, AM - N. Karamyan, AM - L. Davtyan, AM 14:00 Breakout Groups: Participants clinical case discussions (Cases discussion in three groups) Tuesday, 13 November CLINICAL SESSION - GYNECOLOGICAL CANCERS Chairs: F. Peccatori, IT D. Zohrabyan, AM 8:30 Treatment of cervical cancer in highincome countries J. Sehouli, DE 9:00 ASCO resource-stratified guidelines for the treatment of invasive cervical cancer R. Camacho, ES 9:30 Surgery and neoadjuvant chemotherapy in advanced ovarian cancer J. Sehouli, DE 10:00 Systemic treatment of advanced ovarian cancer M. Raza Mirza, DK 10:30 Coffee break

11:00 ESMO/ESGO/ASCO guidelines on endometrial cancer treatment 11:30 HPV vaccination, screening and cervical cancer prevention 12:00 Tumor board discussion of gynecological cancer cases (2 cases) Faculty and local tutors: D. Zohrabyan, AM V.T. Minasyan, AM - A. Mkhitaryan, AM N. Matinyan, AM M. Raza Mirza, DK F. Peccatori, IT 12:40 Lunch break CLINICAL SESSION - PROSTATE CANCER Chairs: V. Badeyan, AM A. Heidenreich, DE 13:30 Management of early and metastatic prostate cancer A. Heidenreich, DE 14:10 Radiotherapy of prostate cancer T. Saghatelyan, AM 14:30 Tumor board discussion of prostate cancer cases (2 cases) Faculty and local tutors: S. Bardakchyan, AM T. Saghatelyan, AM - V. Badeyan, AM N. Matinyan, AM 15:00 Coffee break PROFESSIONAL DEVELOPMENT SESSION II Chairs: G. Tamamyan, AM G. Curigliano, IT 15:30 How to write an article D. Arnold, PT 16:00 New drugs in oncology - Where are we going? M. Raza Mirza, DK 16:30 Learning self-assessment test 17:30 Closing remarks

ORGANISING SECRETARIAT European School of Oncology Via Turati 29 20121 Milan Italy Daniela Mengato Ph: +39 02 85464523 Fax: +39 02 85464545 E-mail: dmengato@eso.net GENERAL INFORMATION APPLICATIONS Alice Ciocchini Ph: +39 02 854 64 529 E-mail: aciocchini@eso.net ATTENDANCE TO THE MASTERCLASS IS BY APPLICATION ONLY Successful applicants are granted free registration and accommodation APPLICATION DEADLINE: 15 JUNE 2018 Information and online application are available at www.eso.net HOW TO APPLY Interested oncologists should apply online at www.eso.net providing: Letter describing motivation for attending; Supporting letter from head of department or mentor; CV with list publications (if the list of publications is not provided, it will be assumed that no articles have been published) Clinical case (see below) Priority will be given to applicants practicing in Caucasus, Eastern Europe, former Soviet Republics and Middle East. CLINICAL CASE PRESENTATION Submit an abstract of one page on the template provided at www.eso.net describing a clinical case related to one of the subjects of the Masterclass (breast, lung, gastrointestinal, gynaecological and prostate cancers). You will have to present your case at the Masterclass in format of a clinical grand round discussion. Please provide a straightforward a case of your daily clinical practice - no uncommon or extremely rare case. A maximum of 10 slides will be permitted containing: Diagnostic considerations Treatment Results, follow-up At least three questions proposed for discussion with the faculty Participants will be asked to bring their personal laptop or tablet (wireless enabled) to the Masterclass as an event-dedicated website will be created and all questionnaires and certificates will be accessible only from there. Any potential problems with meeting this request should be communicated to the secretariat as part of the application process.