Course Schedule: Pharmacotherapy II Spring 2011 Revised 12/6/2010

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Course Schedule: Pharmacotherapy II Spring 2011 Revised 12/6/2010 All lectures will be held from 9:05-11:00 am Monday and Wednesday, as well as 10:10-11:00 am Friday in room MoosT 1-450 and LS 163 (), unless otherwise indicated. Bolded lecturer denotes the provider of the lecture versus faculty colleague in attendance at alternate campus. DATE LECTURE TOPIC Jan. 19 (W) Orientation and Course Overview CV: The CV Continuum Jan. 21 (F) CV: Hypertension I Required Readings: 1. JNC 7 Prevention, Detection, Evaluation and Treatment of High Blood Pressure- Link found on course 2. Rosendorff Circulation 2007;115:2761-2788 Jan. 22 (Sat) Jan. 24 (M) 3. Additional portions of selected studies, TBA Multiple Choice Question Group Project: Deadline to indicate topic preference - after 11AM topics will be assigned randomly. CV: Hypertension II CV: Hypertension III Jan. 26 (W) CV: Hypertension IV Multiple Choice Question Group Project: Topic, group and reviewer assignments distributed. Be SURE you are in a group CV: Hyperlipidemia-Drug Pathophysiology Jan. 27 (Th) Quiz 1 (HTN) due by 8:00 am 01/28/10 Jan. 28 (F) CV: Hyperlipidemia-Drug Therapy I Required Readings: 1.Executive Summary of the Third Report of the Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (ATP III) 2. Implications of Recent Clinical Trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines (White Paper) Grundy Circulation 2004;110:227-239 3. Diagnosis and Management of the Metabolic Syndrome: Grundy Circulation 2005;112:2735-2752 Jan. 31 (M) DiPiro: Chapter 23: Hyperlipidemia CV: Hyperlipidemia-Drug Therapy II CV: Hyperlipidemia-Drug Therapy III

DATE LECTURE TOPIC Feb. 1 (T) Quiz 2 (Lipids) due by 8:00 am 02/02/10 Feb. 2 (W) CV: Review and Case Studies for HTN and Hyperlipidemia CV: ASA and Primary Prevention of CVD Feb. 3 (Th) Pre-exam review for CV Exam #1 (optional) Feb. 4 (F) CV Exam #1 Feb. 7 (M) CV: Introduction to Ischemic Heart Disease DiPiro: Chaper 17: Ischemic Heart Disease 1. ACC/AHA 2002 Guideline Update for the Management of Patients with Chronic Stable Angina-Full Text. Link found on course 2. 2007 Chronic Angina Focused Update of the ACC/AHA 2002 Guidelines for the Management of Patients With Chronic Stable Angina. Link found on course CV: Pharmacotherapy of Chronic Stable Angina Part 1 DiPiro: Chapters 13 & 18: CV Testing and Acute Coronary Syndromes 1. ACC/AHA Guideline 2007 Guidelines for the Management of Patients With Unstable Angina/Non ST- Segment Elevation Myocardial Infarction. Link found on course 2. AHA/ACC 2004 Guidelines for the Management of Patients with ST-Elevation Myocardial Infraction. Link found on course 3. 2007 Focused Update of the ACC/AHA 2004 Guidelines for the Management of Patients With ST- Elevation Myocardial Infarction. Link found on course Feb. 9 (W) CV: Pharmacotherapy of Chronic Stable Angina Part 2 CV: Pharmacotherapy of Acute Coronary Syndromes Part 1 Feb. 10 (Th) Post-exam review of CV Exam 1 (optional) Feb. 11 (F) CV: Pharmacotherapy of Acute Coronary Syndromes Part 2 1. CHEST: Eighth ACCP Conference on Antithrombotic and Thrombolytic Therapy 2008. Link found on Course Many chapters will be helpful. 2. Guide to Anticoagulant Therapy: Heparin (AHA 2001 Scientific Statement). Link found on Course

DATE LECTURE TOPIC Feb. 14 (M) Feb. 16 (W) 3. AHA/ACC Foundation Guide to Warfarin Therapy (AHA 2003 Scientific Statement). Link found on Course CV: Clinical Use of AntiThrombotics in Cardiology CV: Acute Coronary Syndrome Case Review Quiz 3 (CSA and ACS) due by 8:00 am 02/15/10 CV: Introduction to Arrhythmias/Rhythm Recognition CV: Guidelines for the Management of Supraventricular Arrhythmias Required Readings: DiPiro: Chapter 19: Arrhythmias 1. ACC/AHA/ESC 2006 Guidelines for the Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death. Link found on Course 2. ACC/AHA/ESC 2006 Guidelines for the Management of Patients With Atrial Fibrillation. Link found on course 3. Antithrombotic therapy in atrial fibrillation. American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 2008; 133:546S- 592S. Feb. 17 (Th) Pre-exam review for CV Exam #2 (optional) Dr. Schullo-Fuelner Feb. 18 (F) CV Exam #2 Dr. Schullo-Fuelner Feb. 21 (M) Feb. 23 (W) CV: Therapy of Supraventricular Arrhythmias CV: Therapy of Ventricular Arrhythmias CV: ACLS Algorithms part 1: VT/VF and Asystole/PEA CV: ACLS Algorithms part 2: Bradyarrhythmias/Tachyarrhythmias DiPiro: Chapter 14: Cardiopulmonary Arrest 1. 2005 American Heart Association Guidelines for the Management of Cardiopulmonary Resuscitation and Emergency Cardiac Care Part 7.3: Management of Bradycardia and Tachycardia. Link found on Course Feb. 25 (F) 2. 2005 American Heart Association Guidelines for the Management of Cardiopulmonary Resuscitation and Emergency Cardiac Care Part 7.2: Management of Cardiac Arrest. Link found on course CV: Introduction to cardiac hemodynamics and heart failure DiPiro: Chapter 16: Heart Failure

DATE LECTURE TOPIC Chapter 20: Diastolic Heart Failure (pages 315-323) 1. DiPiro: Chapter 20: Diastolic Heart Failure (pages 323-330) 2. ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult. Link found on course Post-exam review of CV Exam #2 (optional) Feb. 28 (M) CV: Pharmacotherapy of HF-I CV: Pharmacotherapy of HF-II Quiz 4 (Arrhythmias) due by 8:00 am 3/01/10 Mar. 2 (W) CV: Treatment of Acute HF-I CV: Treatment of Acute HF-II Mar. 4 (F) CV: HF/Arrhythmia review Mar. 7 (M) CV: Arrhythmia and HF cases Quiz 5 (HF management) due by 8:00 am 3/8/10 Mar. 9 (W) CV: DVT/PE-1 CV: DVT/PE-2 DiPiro: Chapter 21 : Venous Thromboembolism CHEST: Eighth ACCP Conference on Antithrombotic and Thrombolytic Therapy 2008. Prevention of Venous Thromboembolism and Antithrombotic Therapy for Venous Thromboembolic Disease. Link found on Mar. 10 (Th) Pre-exam review for CV Exam #3 (optional) Mar. 11 (F) CV Exam #3 Mar. 14 Mar. 16 Mar. 18 Mar. 21 (M) SPRING BREAK SPRING BREAK SPRING BREAK Endocrine: Orientation & Diabetes ADA Summary Guidelines 2011 (citation tba) ACCORD & ADVANCE trials DiPiro: Chapter 77: Diabetes Mellitus

Mar. 23 (W) Endocrine: Diabetes Mar. 24 (Th) Post exam review of CV Exam #3 (optional) Mar. 25 (F) Endocrine: Diabetes Small Group Case Discussion Multiple Multiple Mar. 28 (M) Endocrine: Diabetes AACE/ADA Consensus Statement - Clinical Endocrinologists and American Diabetes Association Consensus Statement on Inpatient Glycemic Control. Endocrine Practice vol 15 No. 4 May/June 2009; 1-11 Dr. Skaar Mar. 30 (W) QUIZ 1 (Diabetes) due by 8:00 am 3/29/10 Endocrine: Diabetes Wrap-up and Cases Endocrine: Adrenal Therapeutics DiPiro: Chapter 79: Adrenal Gland Disorders Mar. 31 (Th) Pre-exam review for Endocrine Exam #1 (optional) Apr. 1 (F) Endocrine Exam #1 (all diabetes material) Apr. 4 (M) Apr. 6 (W) Endocrine: Thyroid Disorders DiPiro: Chapter 78: Thyroid Disorders Endocrine: Menopause/HRT DiPiro: Chapter 85: Hormone Therapy in Women QUIZ 2 (content from 3/30 to 4/6) due by 8:00 am 4/7/10 Apr. 8 (F) Endocrine: Drugs in Pregnancy and Lactation DiPiro: Chapter 81 Pregnancy and Lactation: Therapeutic Considerations (pgs. 1297-1300, 1309-1310) Apr. 11 (M) Post exam review for Endo Exam #1 (optional) Endocrine: Hormonal Contraception DiPiro: Chapter 82: Contraception Dr. Harris

Apr. 13 (W) Gastrointestinal: GERD DiPiro: Chapter 34: Gastroesophageal Reflux Disease Apr. 14 (Th) Pre-exam review for Endocrine Exam #2 (optional) Apr. 15 (F) Endocrine Exam #2 (material from 3/30-4/11) Apr. 18 (M) Gastrointestinal: Treatment of PUD DiPiro: Chapter 35: Peptic Ulcer Disease (in ) Apr. 20 (W) Mock Oral Exam Apr. 21 (Th) Apr. 22 (F) Apr. 25 (M) Post exam review of Endocrine Exam #2 (optional) Gastrointestinal: Exam #1 (material from 4/13 & 4/18) Gastrointestinal: Inflammatory Bowel Disease (IBD) DiPiro: Chapter 36: Inflammatory Bowel Disease (in ) Apr. 27 (W) Gastrointestinal: Drug-Induced Hepatic Disease DiPiro: Chapter 40: Drug-Induced Liver Disease Stress Ulcers DiPiro: Chapter 35: Peptic Ulcer Disease Optional: Post-exam review of GI exam #1 (TC only) 12:15-1:15 Location: 7-193/195 **Apr. 28 (TH)* ORAL EXAM Multiple Multiple Apr. 29 (F) May 2 (M) PHARMACY DAY!!! Gastrointestinal: Viral Hepatitis DiPiro: Chapter 42: Viral Hepatitis Optional: Post-exam review of GI exam #1 ( only) 12:15-1:15 Location: LSci 163 (in ) May 4 (W) Gastrointestinal: Diarrhea & Constipation DiPiro: Chapter 38: Diarrhea, Constipation (and Irritable Bowel Syndrome - NOT required) May 6 (F) May 9-13 Final Exam Week Gastrointestinal: Exam #2 (material from 4/25-5/4) Phar 6122 Comprehensive Final Written Exam 3 hours All