The functional anatomy of the urinary system. Human Anatomy Department Dr. Anastasia Bendelic

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Transcription:

The functional anatomy of the urinary system Human Anatomy Department Dr. Anastasia Bendelic

Plan Development of the kidneys and their abnormalities Development of the urinary ways and their abnormalities Kidney structure, topography, functions Ureter structure, topography, function Urinary bladder structure, topography, function Male and female urethra structural peculiarities, functions

Kidney development The kidney develop from intermediate mesoderm (or nephrogenic mesoderm).

Intermediate mesoderm The intermediate mesoderm gives rise to the kidney and indifferent gonad.

Kidney development or nephrogenesis The development of the kidney includes a series of successive phases: Pronephros; Mesonephros; Metanephros.

Kidney development or nephrogenesis Pronephros pronephric tubules, pronephric duct; Mesonephros mesonephric tubules, mesonephric duct or Wolffian duct; Metanephros ureteric bud (or metanephric diverticulum), metanephric blastema.

Kidney development or nephrogenesis

Abnormalities Bifid renal pelvis and ureter result from division of the metanephric diverticulum (ureteric bud). It may be unilateral or bilateral. Retrocaval ureter passes posterior to the inferior vena cava. Supernumerary kidney develops as a result of splitting of the metanepfric blastema. Renal agenesis ureteric bud fails to develop. Horseshoe kidney the inferior poles of the kidney are fused. Multichystic dysplastic kidney is characterized by presence of multiple, non-communicating cysts. Ectopic pelvic kidney fails to climb towards its normal position.

Double and bifid ureter

Supernumerary kidneys

Unilateral renal agenesis

Horseshoe kidney

Multicystic dysplastic kidney

Ectopic pelvic kidney

Urinary system consists of: Kidneys which produce urine; Ureters which carry urine from the kidneys; Urinary bladder which temporarily stores urine; Urethra which conducts urine from the urinary bladder to the exterior.

Kidney (ren, nephros) The kidneys remove the excess water, salts and wastes of the protein metabolism and form the urine. They lie retroperitoneally on the posterior abdominal wall on each side of the vertebral column at the level of T12 L3 vertebrae. The right kidney lies slightly inferior to the left kidney, owing to its relationship to the liver.

Kidney (ren, nephros)

Kidney is bean-shaped and has: two surfaces: anterior and posterior; two borders: medial and lateral; two ends (or poles): superior and inferior. On the medial border the renal hilum is located, where the renal artery enters, and renal vein and renal pelvis (or ureter) leave the renal sinus.

Fixation apparatus of kidney: Renal (muscular) bed (or seat); Renal pedicle (renal artery, renal vein, ureter); Renal capsules (fibrous and adipose capsules); Renal fascia or Gerota`s fascia (consits of prerenal and retrorenal laminae); Peritoneum; Intra-abdominal pressure.

Fixation apparatus of kidney:

Internal (macro-microscopic) structure of kidney 1. Renal parenchyma: Renal cortex outer layer of kidney; Renal medulla inner layer of kidney arranged into the pyramids. 2. Renal sinus

Internal (macro-microscopic) structure of kidney Renal lobe comprises a renal pyramid as well as renal cortex which surrounds it. Renal segment consists of 2 3 renal lobes. There are 5 renal segments: 1. superior segment; 2. inferior segment; 3. anterior superior segment; 4. anterior inferior segment; 5. posterior segment.

Segmental structure of the kidney

Nephron functional and structural unit of kidney There are about 1.000.000 nephrons in each human kidney. Each nephron consists of two parts: Renal corpuscle, producing primary urine (150-180 l/ 24 hours); Renal tubule, producing secondary urine (1,5-2 l/ 24 hours).

Nephron functional and structural unit of kidney Renal corpuscle comprises: 1. glomerulus (a network of capillaries); 2. Bowman`s capsule or glomerular capsule. Renal tubule consists of: 1. proximal convoluted tubule; 2. loop of Henle; 3. distal convoluted tubule. The final urine is conveyed through the collecting ducts, papillary ducts into the renal calyces and pelvis.

Nephron functional and structural unit of kidney

Nephron functional and structural unit of kidney There are two kind of nephrons: Cortical nephrons (80%), which have short loops of Henle; Juxtamedullary nephrons (20%) have long loops of Henle, that extend deep into the renal medulla.

Urine formation The three processes of urine formation are, as follows: (glomerular) filtration, (tubular) reabsorption, (tubular) secretion.

Nephron functional and structural unit of kidney

Renal sinus The renal sinus is a space of within the kidney, which is occupied by: minor renal calyces, major renal calyces; renal pelvis; vessels; nerves; variable amount of fat.

Renal sinus

Ureters muscular tubes, which connect the kidneys to the urinary bladder; have 3 parts: abdominal, pelvic, intramural ( or intravesical); their walls consist of 4 layers: mucosa, submucosa, muscular and adventitious coats.

Ureters

Urinary bladder when empty, the adult urinary bladder is located in the pelvic cavity; In infants and young children is in the abdominal cavity even empty; it is separated from the pubic bones by the retropubic space (of Retzius); its neck is held firmly by the puboprostatic ligament in males and pubovesical ligament in females.

Urinary bladder It has 4 parts: a) apex of the bladder; b) body of the bladder; c) fundus of the bladder; d) neck of the bladder. The ureteric orifices and the internal urethral orifice are at the angles of the trigone of the bladder.

Urinary bladder

Urinary bladder Its walls consists of: a) Mucosa, which forms the folds, except of the trigone of the bladder; b) Submucosa, absent at the level of the trigone; c) Muscular coat which forms the detrusor muscle and internal uretheral sphincter; d) Serous coat (visceral peritoneum).

Urinary bladder

Female urethra It is a short fibromuscular tube (3-5 cm). It lies anterior to the vagina. It begins at the neck of the urinary bladder by the internal urethral orifice (or ostium). It opens into the vestibule of vagina by the external urethral orifice (or ostium). It has two parts: 1. intramural part (corresponds with the neck of bladder); 2. perineal part (which pierces the urogenital diaphragm of perineum).

Female urethra

Male urethra It is a fibromuscular tube that begins at the neck of the urinary bladder (internal urethral orifice) and ends at the level of the glands penis (external urethral orifice). It is significantly longer in males than females (20 cm). It consists of four parts: 1. preprostatic (or intramural) part (0,5 cm); 2. prostatic part (3 cm); 3. membranous part (1 cm); 4. spongy part (16 cm).

Male urethra

Urethra It is a passageway for urine. It serves an additional purpose in men, as it is also utilized as a passageway for semen during ejaculation. Male urethra: 1. anterior urethra; 2. posterior urethra. Male urethra: 1. fixed part (pelvic part): 2. mobile part (penile part).

Urethra, gender differences

Urethral catheterization It is done to remove urine from a person who is unable to micturate.

Urinary system