MR-Guided Radiation Therapy: The Next Frontier in Radiation Oncology

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MR-Guided Radiation Therapy: The Next Frontier in Radiation Oncology Friday, May 17, 2019 UCLA Meyer & Renee Luskin Conference Center Los Angeles, CA

MR-Guided Radiation Therapy: The Next Frontier in Radiation Oncology Course Description Radiation therapy is a mainstay treatment for cancer. Magnetic Resonance Imaging has been recently integrated into the treatment room, providing for the first time the advantages of real-time soft tissue imaging and concurrent radiation treatments. Benefits of MR-Guided Radiation Therapy (MRgRT) include superior soft tissue imaging, the ability to track tumors and gate treatment delivery, and the opportunity to adapt for inter- and intra-fraction anatomical variations. MRgRT also offers the potential for providing sophisticated biomarker guided treatments. As clinical adoption of MRgRT expands, there is a need to develop work flows and quality assurance techniques, innovate imaging science, and assess clinical outcome benefits. This course will update the status of MRgRT, examine clinical treatment scenarios, provide strategies to overcome implementation challenges, and review current research programs designed to explore the benefits of MRgRT. Target Audience Radiation oncologists, medical physicists, dosimetrists, radiation therapists, other allied health professionals, and trainees interested in exploring the benefits and challenges of MRgRT. Course Objectives At the conclusion of the course, participants should be better able to: List the benefits of MRgRT over conventional modern radiation therapy. Discuss the challenges and strategies of implementing MRgRT. Compare the benefits and limitations of the currently available MRgRT systems. Describe the adaptive radiation therapy work flow. Describe the application of MRgRT in clinical scenarios such as head and neck, pancreas, liver, and prostate cancers. Describe current research developing and integrating functional imaging for personalized radiation therapy prescriptions.

Faculty COURSE DIRECTORS Percy Lee, MD Associate Professor & Vice Chair of Education Chief, Thoracic Radiation Oncology Ann Raldow, MD, MPH Chief, Gastrointestinal Oncology Minsong Cao, PhD Associate Professor Associate Vice Chair of Education Daniel Low, PhD Professor & Vice Chair of Physics GUEST FACULTY Michael Bassetti, MD University of Wisconsin School of Medicine & Public Health Madison, Wisconsin Olga Green, PhD Chief of Service for Adaptive MR-Guided Radiotherapy Program Washington University School of Medicine St. Louis, Missouri Allen Li, PhD Professor & Chief of Medical Physics Medical College of Wisconsin Milwaukee, Wisconsin UCLA FACULTY Robert Chin, MD, PhD Paul Finn, MD Professor UCLA Radiology Peng Hu, PhD Associate Professor UCLA Radiology Amar Kishan, MD James Lamb, PhD Ke Sheng, PhD Professor Michael L. Steinberg, MD Professor & Chair Yingli Yang, PhD

Program 7:00 Breakfast & Registration 8:00 Welcome & Introduction Percy Lee, MD Session I: Introduction to MRgRT Basics 8:10 Introduction to Clinical MR Sequences Peng Hu, PhD 8:40 MR Safety James Lamb, PhD 9:10 QA/QC for MRgRT System Olga Green, PhD 9:40 Break MR-Guided RT Systems & Work Flow Moderator: Percy Lee, MD 10:00 System Overview, Comparison & Debate Allen Li, PhD and Daniel Low, PhD, Session II: Technical Features and Benefits 11:00 Motion Management Minsong Cao, PhD 11:30 Work Flow, Adaptive Planning & Percy Lee, MD New Process of Care 12:00 Lunch MR-Guided RT Systems & Work Flow 1:00 GI Pancreas Ann Raldow, MD, MPH 1:25 GI Liver Michael Bassetti, MD 1:50 GU/Prostate Bladder Amar Kishan, MD 2:15 Head & Neck Robert Chin, MD, PhD 2:40 Break Session III: Advanced MR Technologies 3:00 Functional MRI Yingli Yang, PhD 3:30 Novel Contrast Imaging Paul Finn, MD 4:00 Future of MRgRT Ke Sheng, PhD 4:30 The Promise of MRgRT Michael L. Steinberg, MD 5:00 Reception at UCLA Luskin Conference Center

Accreditation Statement The Office of Continuing Medical Education, David Geffen School of Medicine at UCLA is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The Office of Continuing Medical Education, David Geffen School of Medicine at UCLA, designates this live activity for a maximum of 7 AMA PRA Category 1 Credits TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity. This course will offer Medical Physics Continuing Education Credit (MPCEC) and Medical Dosimetry Certification Board Continuing Education Credit (MDCB). Disclosure Statement The FDA has issued a concept paper that classifies commercial support of scientific and educational programs as promotional unless it can be affirmed that the program is truly independent and free of commercial influence. In addition to independence, the FDA requires that non-promotional, commercially supported education be objective, balanced and scientifically rigorous. The policy further states that all potential conflicts of interest of the CME staff and faculty be fully disclosed to the program s participants. In addition, Accreditation Council for Continuing Medical Education policy mandates that the provider adequately manages all identified potential conflicts of interest prior to the program. UCLA fully endorses the letter and spirit of these concepts.

General Information Location UCLA Luskin Conference Center 425 Westwood Plaza Los Angeles, CA 90095 (855) 522-8252 Parking From the 405 freeway, exit Wilshire Blvd. East toward Westwood. Turn left on Westwood Blvd., travel past Charles E. Young Dr. South and turn left on Parking Structure 8 Driveway. Proceed up the ramp to the rooftop level to park. Pay-by-plate machines are available on the rooftop level. Credit cards are accepted. A pedestrian walkway/bridge connects Parking Structure 8 to the Luskin Conference Center. Take the east stairs down one level (from Level 4 to Level 3) and cross over Strathmore Place. The entrance will be on your right-hand side. Local Accommodations UCLA Luskin Conference Center 425 Westwood Plaza Los Angeles, CA 90095 Reservations: (855) 522-8252 Hotel Palomar 10740 Wilshire Blvd. Los Angeles, CA 90024 Reservations: (310) 475-8711 W Los Angeles Westwood Hotel 930 Hilgard Avenue Los Angeles, CA 90024 Reservations: (310) 208-8765 Fees Physicians and Physicists: $350 Dosimetrists, Therapists and Allied Health Professionals: $200 Trainees: $150 Enrollment Online: Go to www.cme.ucla.edu/courses and click on MR-Guided Radiation Therapy: The Next Frontier in Radiation Oncology. You may use your MasterCard, Visa, American Express or Discover card to register. By Mail: Mail the attached form to: UCLA Office of Continuing Medical Education David Geffen School of Medicine at UCLA MR-Guided Radiation Therapy 10920 Wilshire Blvd., Suite 1060 Los Angeles, CA 90024-6512 By Fax: Send the completed enrollment form with credit card information and authorizing signature to (310) 794-2624 By Phone: Call (310) 794-2620 Refunds Cancellations must be received in writing by Monday, May 6, 2019 and will be subject to a $50 processing fee. No refunds will be granted after that date. If, for any reason, the course must be cancelled, discontinued, or rescheduled by the Office of Continuing Medical Education, a full refund will be provided.

Application for Enrollment Winter 2018 (please print) Course Title and Number MR-Guided Radiation Therapy: The Next Frontier in Radiation Oncology Physicians and Physicists: $350 Dosimetrists, Therapists and Allied Health Professionals: $200 Trainees: $150 M189-26 Total Registration Fee Last four digits of your Social Security Number Name (First/Middle/Last) Degree Preferred Mailing Address City / State / Zip ( ) ( ) Area Code Phone Area Code Fax E-Mail Address Check enclosed payable to: The Regents of the University of California Charge: MasterCard Visa Discover American Express Card Number Expiration Mo/Yr Signature Mail to: Office of Continuing Medical Education, David Geffen School of Medicine at UCLA, MR-Guided Radiation Therapy, 10920 Wilshire Blvd., Suite 1060, Los Angeles, CA 90024-6512 Fax: (310) 794-2624 (must include charge card information and authorizing signature) Call: (310) 794-2620 Register online: www.cme.ucla.edu/courses/

Office of Continuing Medical Education David Geffen School of Medicine at UCLA 405 Hilgard Avenue MC29 Los Angeles, CA 90095-6938 MR-Guided Radiation Therapy: The Next Frontier in Radiation Oncology Friday, May 17, 2019 UCLA Meyer & Renee Luskin Conference Center Los Angeles, CA PAID