Welcome and introducing ESHRE

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ESHRE European Society of Human Reproduction and Embryology Welcome and introducing ESHRE János Rigó Semmelweis University Faculty of Medicine 1st Department of Obstetrics and Gynaecology ESHRE guidelines for the diagnosis and treatment of endometriosis. Presentation and interactive discussion ESHRE Campus Hungary, 26 February 2010 Conflict of interest/potential bias Full Professor and Head 1st Department of Obstetrics and Gynaecology Semmelweis University Faculty of Medicine No conflict of interest

What is ESHRE? The European Society of Human Reproduction and Embryology was founded in 1985. Mission Statement: to promote interest in, and understanding of, reproductive science and medicine. It does this through facilitating research and subsequent dissemination of research findings in human reproduction and embryology to the general public, scientists, clinicians and patient associations; it also works to inform politicians and policy makers throughout Europe. to promote improvements in clinical practice through organising teaching, training and continuing medical education activities, developing and maintaining data registries and implementing methods to improve safety and quality assurance in clinical and laboratory procedures. ESHRE Membership ESHRE represents over 5,300 members (infertility specialists, embryologists, geneticists, stem cell scientists, developmental biologists, technicians and nurses) Overall, the membership is distributed over 114 different countries, with 50% of members from Europe (EU). 11% come from the US, India and Australia. Executive Committee 2009/2011 Chairman Chairman Elect Past Chairman Luca Gianaroli Anna Veiga Joep Geraedts Italy Spain Netherlands Jean François Guérin France Timur Gürgan Turkey Ursula Eichenlaub-Ritter Germany Antonis Makrigiannakis Greece Miodrag Stojkovic Serbia Anne-Maria Suikkari Finland Carlos Plancha Portugal Françoise Shenfield United Kingdom Etienne Van den Abbeel Belgium Heidi Van Ranst Belgium Veljko Vlaisavljevic Slovenia Søren Ziebe Denmark

General Assembly of Members Executive Committee Committee of Nat. Representatives Central Office ESHRE Consortia EIM Consortium PGD Consortium Sub-Committees Finance Sub-Committee Comm. Sub-Committee Publ. Sub-Committee Editorial Office Publisher Editors-in-Chief Int l Scientific Committee SIG Sub-Committee Andrology Early Pregnancy Embryology Endometriosis & Endometrium Ethics & Law Paramedical Group Psychology & Counselling Reproductive Endocrinology Reproductive Genetics Reproductive Surgery Safety & Quality in ART Stem Cells Task Forces Other (shared) Consortia EACC SIG Coordinators Embryology Certification Working Group Ethics & Law Working Group Developing Countries Basic Scientists Demography, Epidemiology and Fertility Preservation Cross Border Treatment Health economics PGS Mild IVF ESHRE Activities Annual Meeting One of the most important events in reproductive science and medicine Steady increase in terms of attendance and of scientific recognition Track record: ESHRE 2008 Barcelona: 7559 participants ESHRE 2009 Amsterdam: 8132 participants Future meetings: ESHRE 2010 Rome, 27-30 June 2010 ESHRE 2011 Stockholm, 3-6 July 2011 Annual Meeting Rome, Italy 27 June to 30 June 2010 Pre-congress courses (27 June): PCC 1: Cross-border reproductive care: information and reflection PCC 2: From gametes to embryo: genetics and developmental biology PCC 3: New developments in the diagnosis and management of early pregnancy complications PCC 4: Basic course on environment and human male reproduction PCC 5: The lost art of ovulation induction PCC 6: Endometriosis: How new technologies may help PCC 7: NOTES and single access surgery PCC 8: Stem cells in reproductive medicine PCC 9: Current developments and their impact on counselling PCC 10: Patient-centred fertility care PCC 11: Fertility preservation in cancer disease PCC 12: ESHRE journals course for authors

Annual Meeting Scientific Programme (1/2) Rome, Italy 27 June to 30 June 2010 Molecular timing in reproduction Rise and decline of the male Pluripotency Preventing maternal death Use and abuse of sperm in ART Live surgery Emerging technologies in the ART laboratory Debate: Multiple natural cycle IVF versus single stimulated cycle and freezing Annual Meeting Scientific Programme (2/2) Fertility preservation Congenital malformations ESHRE guidelines Data from the PGD Consortium European IVF Monitoring 2007 Debate: Selection of male/female gametes Third party reproduction in the United States Debate: Alternative Medicine, patients feeling in control? Historical lecture: Catholicism and human reproduction ESHRE Activities Scientific Journals Human Reproduction with impact factor 3.773 Human Reproduction Update with impact factor 7.590 Molecular Human Reproduction with impact factor 2.537

ESHRE Activities Campus and Data Collection Educational Activities / Workshops Meetings on dedicated topics are organised across Europe Organised by the Special Interest Groups Visit: www.eshre.com under CALENDAR Data collection and monitoring EIM data collection PGD data collection Cross border reproductive care survey Special Interest Groups (SIGs) The SIGs reflect the scientific interests of the Society s membership and bring together members of the Society in sub-fields of common interest Andrology Early Pregnancy Embryology Endometriosis / Endometrium Ethics & Law Safety & Quality in ART Psychology & Counselling Reproductive Genetics Reproductive Surgery Stem Cells Reproductive Endocrinology Significance of endometriosis ~10% women of reproductive age Associated with pelvic pain and infertility Economical consequences Unknown etiology

Etiology Ectopic transplantation of endometrial tissue Coelomic metaplasia Induction theory Endometriosis symptoms Pain Subfertility 45% of women investigated for pelvic pain have endometriosis Endometriosis 20-40% of women with subfertility have endometriosis Diagnosis and therapy Diagnosis: Laparoscopy (visualization / histology) Promising non-invasive techniques Classification: (rafs, Enzian) Therapy: Surgical Medical Standardisation of the diagnosis and therapy is needed ESHRE guidelines for endometriois