TRACE ELEMENTS IN SERUM Proficiency Test Report Event #, 0 July 5 th, 0
Event #, 0 Serum Aluminum Serum materials were obtained from the Dutch EQA (External Quality Assessment) scheme SKML (Stichting Kwaliteitsbewaking Medische Laboratoria) as part of a global collaborative exercise to harmonize international measurements of Al, Cu, Se and Zn in serum. Additionally, serum pools were spiked with a suite of trace elements (Co, Cr, Li, Mg, Mn, Tl, and V), including aluminum as AlCl at various concentrations. The serum has been tested and found to be negative for BSE (Bovine Spongiform Encephalopathy), and free of pathogens. The Certificate of Analysis provided by SKML is available upon request. The Target Value assigned for each PT material is the robust mean of the results reported by all participants in this event. The robust statistics were obtained utilizing algorithms based on those presented in ISO 58:005E Statistical methods for use in proficiency testing by interlaboratory comparisons. Values for serum aluminum range from 8 µg/l (.0 µmol/l) to 00 µg/l (7. µmol/l). Acceptable ranges for serum aluminum are based on fixed criteria of ±0%, or ±5 µg/l below 5 µg/l. These criteria are based on consensus recommendations from several EQAS organizers (). Discussion. Based on the above criteria, 9.9% of test results reported were judged as satisfactory, with one out of participant laboratories (.%) reporting or more of the 5 results outside the acceptable ranges.. Taylor, A., Angerer, J., Claeys, F., Kristiansen, J., Mazarrasa, O., Menditto, A., Patriarca, M., Pineau, A., Schoeters, I., Sykes, C., Valkonen, S. and Weykamp, C. Comparison of procedures for evaluating laboratory performance in external quality assessment schemes for lead in blood and aluminum in serum demonstrates the need for common quality specifications. Clinical Chemistry 00 8 000-007. Trace Elements PT Program www.wadsworth.org/testing/lead/index.htm
Serum Aluminum Test Results, 0 Event # ROBUST STATISTICAL SUMMARY TARGET VALUE ASSIGNMENT AND STATISTICS SE-06 SE-07 SE-08 SE-09 SE-0 Robust Mean 77 0 00 8 6 Robust Standard Deviation Standard Uncertainty RSD (%) 6 7.9 9 7. 6..8 7.7 Number of Sample Measurements Acceptable Range: Upper Limit: 9 56 0 75 Lower Limit: 6 0 60 7 notes: Results reported as less than the method detection limit are excluded from statistical calculations.
Serum Aluminum Test Results, 0 Event # PERFORMANCE OF PARTICIPATING LABORATORIES Lab Code Method SE-06 SE-07 SE-08 SE-09 SE-0 Info Only Target Values: 77 0 00 8 6 0 ETAAS-Z 8 8 08 0 5 ICP-MS 6 80 0 8 7 FAAS 8 98 5 Info 56 ICP-MS 80. 5 0 8.5 60 60 ETAAS-Z 78 7 9 9 5 6 ICP-MS 76 6 9 6 0 79 DRC/CC-ICP-MS 7 5 0 97 ICP-MS 80 87 5 00 DRC/CC-ICP-MS 78 9 9 59 Info 06 DRC/CC-ICP-MS 76 >00.0 >00.0 5 >00.0 87 ETAAS-Z 76 0 0 8 5 9 ICP-MS 7 9 9 Info 05 ICP-MS 78 7 9 ICP-MS 7 9 8 Info 5 ETAAS-Z 7 96 Info 55 ICP-MS 9 6 57 ICP-MS 78 98 9 5 58 ICP-MS 8 8 09 0 5 6 ICP-MS 76 6 0 8 6 ICP-MS 8 5 06 5 66 ETAAS-Z 69 7 5 Info 0 ICP-AES/OES 9 70 9 9 8 Info 58 ETAAS Other 7 7 5 5 Percent satisfactory results for all participants: 9.9 % notes: reported outside upper limit Info only: results included for informational purposes only. reported outside lower limit notes: Results reported as less than the method detection limit are excluded from statistical calculations.
DRC/CC-ICP-MS New York State Department of Health Serum Aluminum Test Results, 0 Event # STATISTICAL SUMMARY BY METHOD ETAAS Other ETAAS-Z FAAS ICP-AES/OES ICP-MS All Laboratories SE-06 SE-07 SE-08 SE-09 SE-0 75 7 5 76 6 7.9 8 9 78 7 9.6 78 7 9.0 0 7 5 0 7.7 70 7 5. 8 6. 5 5 5 9 7. 98 9 00 6. 97. 5 7 0.8 9 9 7. 8 6 0. 5 5 5 9.8 5 8 6 8. 8.6 notes: Insufficient data for calculation.
Event #, 0 Serum Copper Serum materials were obtained from the Dutch EQA (External Quality Assessment) scheme SKML (Stichting Kwaliteitsbewaking Medische Laboratoria) as part of a global collaborative exercise to harmonize international measurements of Al, Cu, Se and Zn in serum. Additionally, serum pools were spiked with a suite of trace elements (Co, Cr, Li, Mg, Mn, Tl, and V), including copper as CuCl at various concentrations. The serum has been tested and found to be negative for BSE (Bovine Spongiform Encephalopathy), and!free of pathogens. The Certificate of Analysis provided by SKML is available upon request. The Target Value assigned for each PT material is the robust mean of the results reported by all participants in this event. The robust statistics were obtained utilizing algorithms based on those presented in ISO 58:005E Statistical methods for use in proficiency testing by interlaboratory comparisons. Values for serum copper range from 98 µg/l (.5 µmol/l) to 00 µg/l (8.78 µmol/l). Acceptable ranges for serum copper are based on fixed criteria of ±5%, or ±95 µg/l below 65 µg/l. These criteria are consistent with those proposed by the OELM Network of EQAS organizers (, ) for trace elements in serum, and are slightly less stringent than those previously suggested for NYS (±0%). Discussion. Based on the above criteria, 9.6% of test results reported were judged as satisfactory, with two out of 9 participant laboratories (0.5%) reporting or more of the 5 results outside the acceptable ranges.. A. Taylor, J. Angerer, J. Arnaud, F. Claeys, R.L. Jones, O. Mazarrasa, E. Mairiaux, A. Menditto, P.J. Parsons, M. Patriarca, A. Pineau, S. Valkonen, J.-P. Weber and C. Weykamp Accreditation and Quality Assurance 006 0-5.. J. Arnaud, J.-P. Weber, C.W. Weykamp, P.J. Parsons, J. Angerer, E. Mairiaux, O. Mazarrasa, S. Valkonen, A. Menditto, M. Patriarca, and A. Taylor Clinical Chemistry 008 5 89-899. Trace Elements PT Program www.wadsworth.org/testing/lead/index.htm
Serum Copper Test Results, 0 Event # ROBUST STATISTICAL SUMMARY TARGET VALUE ASSIGNMENT AND STATISTICS SE-06 SE-07 SE-08 SE-09 SE-0 Robust Mean 558 98 00 98 6 Robust Standard Deviation Standard Uncertainty RSD (%) 5 7.9 8 0 6. 57 7 8. 60 7 6.6 7 50 7. Number of Sample Measurements 9 9 9 9 9 Acceptable Range: Upper Limit: 79 58 565 056 778 Lower Limit: 868 65 780 05 notes: Results reported as less than the method detection limit are excluded from statistical calculations.
Serum Copper Test Results, 0 Event # PERFORMANCE OF PARTICIPATING LABORATORIES Lab Code Method SE-06 SE-07 SE-08 SE-09 SE-0 Info Only Target Values: 558 98 00 98 6 07 DRC/CC-ICP-MS 69 9 08 9 58 Info 0 ICP-MS 7 7 0 007 675 ICP-MS 90 50 960 890 0 7 ICP-MS 557 0 95 8 Info 56 ICP-AES/OES 660 0 90 978 60 60 ETAAS-Z 650 0 950 80 70 6 ICP-MS 05 88 86 58 79 DRC/CC-ICP-MS 560 0 080 900 0 97 ICP-MS 50 0 50 900 70 00 ICP-MS 87 578 505 09 775 Info 06 ICP-MS 0 0 900 860 0 9 ICP-MS 5 079 06 88 6 Info 05 ICP-MS 80 80 950 870 0 ICP-MS 5 5 58 95 68 Info 5 ICP-MS 700 900 9000 9500 000 Info 59 ICP-MS 0 00 97 9 50 66 ETAAS-Z 57 5 70 96 0 Info 0 DRC/CC-ICP-MS 60 907 68 890 9 Info 57 ICP-AES/OES 595 8 9 90 99 Info Percent satisfactory results for all participants: 9.6 % notes: reported outside upper limit Info only: results included for informational purposes only. reported outside lower limit notes: Results reported as less than the method detection limit are excluded from statistical calculations.
DRC/CC-ICP-MS New York State Department of Health Serum Copper Test Results, 0 Event # STATISTICAL SUMMARY BY METHOD ETAAS-Z ICP-AES/OES ICP-MS All Laboratories SE-06 SE-07 SE-08 SE-09 SE-0 56 0 6 5 68 6 69 60.9 9 66 89 7.9 0 05 9 56 6 9 8 86 8.5 9 9 7 7.8 969 0 85 8 05 6.9 8 079 6 7.7 908 88 75 99 9 7 8.0 8 99 6 6.9 6 0 560 86 50 9. 9 6 66 5.5 notes: Insufficient data for calculation.
Event #, 0 Serum Selenium Serum materials were obtained from the Dutch EQA (External Quality Assessment) scheme SKML (Stichting Kwaliteitsbewaking Medische Laboratoria) as part of a global collaborative exercise to harmonize international measurements of Al, Cu, Se and Zn in serum. Additionally, serum pools were spiked with a suite of trace elements (Co, Cr, Li, Mg, Mn, Tl, and V), including selenium as SeO at various concentrations. The serum has been tested and found to be negative for BSE (Bovine Spongiform Encephalopathy), and free of pathogens. The Certificate of Analysis provided by SKML is available upon request. The Target Value assigned for each PT material is the robust mean of the results reported by all participants in this event. The robust statistics were obtained utilizing algorithms based on those presented in ISO 58:005E Statistical methods for use in proficiency testing by interlaboratory comparisons. Values for serum selenium range from 5 µg/l (0. µmol/l) to 5 µg/l (.0 µmol/l). Acceptable ranges for serum selenium are based on fixed criteria of ±0%, or ± µg/l below 0 µg/l. These criteria are a little less stringent than those proposed by the OELM Network of EQAS organizers (±5% or ±8 µg/l below 55 µg/l) (, ) for trace elements in serum. As performance for serum Se improves among NYS-permit laboratories, consideration will be given to adopting the OELM criteria. Discussion. We have become aware of a potential interference on Se in ICP-MS when sera from bovine sources are used for PT sample pools. We are currently investigating this and will report on our findings in due course. Until that time, grading for serum Se is suspended. We ask that participants continue to analyze our serum pools for Se, along with other trace elements, to aid in the investigation. We included human sera for comparison purposes with this PT event (SE-6 through 0), and we requested participant s cooperation by analyzing these additional materials for Se. We will shortly be circulating a summary of the results, as well as from the questionnaire which asked for more details of the analytical methods used for Se.. A. Taylor, J. Angerer, J. Arnaud, F. Claeys, R.L. Jones, O. Mazarrasa, E. Mairiaux, A. Menditto, P.J. Parsons, M. Patriarca, A. Pineau, S. Valkonen, J.-P. Weber and C. Weykamp Accreditation and Quality Assurance 006 0-5.. J. Arnaud, J.-P. Weber, C.W. Weykamp, P.J. Parsons, J. Angerer, E. Mairiaux, O. Mazarrasa, S. Valkonen, A. Menditto, M. Patriarca, and A. Taylor Clinical Chemistry 008 5 89-899. Trace Elements PT Program www.wadsworth.org/testing/lead/index.htm
Serum Selenium Test Results, 0 Event # ROBUST STATISTICAL SUMMARY TARGET VALUE ASSIGNMENT AND STATISTICS SE-06 SE-07 SE-08 SE-09 SE-0 Robust Mean 8 6 5 5 95 Robust Standard Deviation Standard Uncertainty RSD (%) 6. 0.6 5 9. 7 8.5. Number of Sample Measurements 5 5 5 5 5 Acceptable Range: Upper Limit: 0 9 0 0 Lower Limit: 6 9 0 0 76 notes: Results reported as less than the method detection limit are excluded from statistical calculations.
Serum Selenium Test Results, 0 Event # PERFORMANCE OF PARTICIPATING LABORATORIES Lab Code Method SE-06 SE-07 SE-08 SE-09 SE-0 Info Only Target Values: 8 6 5 5 95 07 DRC/CC-ICP-MS 75 0 5 8 90 Info 0 DRC/CC-ICP-MS 69 0. 0 8. ICP-MS 99 7 5 66 7 DRC/CC-ICP-MS 8 0 60 5 Info 56 ICP-MS 8 8.5 7 99 6 DRC/CC-ICP-MS 9 8 66 0 79 DRC/CC-ICP-MS 88 56 9 00 DRC/CC-ICP-MS 80 9 5 6 0 Info 06 DRC/CC-ICP-MS 8 8 8 95 9 DRC/CC-ICP-MS 7 00 9 87 Info 05 ICP-MS 90 0 6 9 89 ICP-MS 87 0 6 87 Info 66 ETAAS-Z 0 50 9 97 5 Info 67 DRC/CC-ICP-MS 67 0 0 0 8 Info 0 DRC/CC-ICP-MS 80 08 8 65 9 Info Percent satisfactory results for all participants: 00.0 % notes: reported outside upper limit Info only: results included for informational purposes only. reported outside lower limit notes: Results reported as less than the method detection limit are excluded from statistical calculations.
DRC/CC-ICP-MS New York State Department of Health Serum Selenium Test Results, 0 Event # STATISTICAL SUMMARY BY METHOD ETAAS-Z ICP-MS All Laboratories SE-06 SE-07 SE-08 SE-09 SE-0 0 79 9.8 0 90 7.8 5 8 5.8 0 9 8. 50 9 7. 5 8. 9.9 9 5 6. 0 5 9 7.6 97 5 5 6. 5 5 8. 0 9 0 0. 5 99 6 5.7 5 98.5 notes: Insufficient data for calculation.
Event #, 0 Serum Zinc Serum materials were obtained from the Dutch EQA (External Quality Assessment) scheme SKML (Stichting Kwaliteitsbewaking Medische Laboratoria) as part of a global collaborative exercise to harmonize international measurements of Al, Cu, Se and Zn in serum. Additionally, serum pools were spiked with a suite of trace elements (Co, Cr, Li, Mg, Mn, Tl, and V), including zinc as ZnCl at various concentrations. The serum has been tested and found to be negative for BSE (Bovine Spongiform Encephalopathy), and free of pathogens. The Certificate of Analysis provided by SKML is available upon request. The Target Value assigned for each PT material is the robust mean of the results reported by all participants in this event. The robust statistics were obtained utilizing algorithms based on those presented in ISO 58:005E Statistical methods for use in proficiency testing by interlaboratory comparisons. Values for serum zinc range from µg/l (7.0 µmol/l) to 888 µg/l (.7 µmol/l). Acceptable ranges for serum zinc are based on fixed criteria of ±5%, or ±5 µg/l below 00 µg/l. These criteria are consistent with those proposed by the OELM network of EQAS organizers () for trace elements in serum. Discussion. Based on the above criteria, 87.7% of test results reported were judged as satisfactory, with four out of 6 participant laboratories (5. %) reporting or more of the 5 results outside the acceptable ranges.. A. Taylor, J. Angerer, J. Arnaud, F. Claeys, R.L. Jones, O. Mazarrasa, E. Mairiaux, A. Menditto, P.J. Parsons, M. Patriarca, A. Pineau, S. Valkonen, J.-P. Weber and C. Weykamp Accreditation and Quality Assurance 006 0-5.. J. Arnaud, J.-P. Weber, C.W. Weykamp, P.J. Parsons, J. Angerer, E. Mairiaux, O. Mazarrasa, S. Valkonen, A. Menditto, M. Patriarca, and A. Taylor Clinical Chemistry 008 5 89-899. Trace Elements PT Program www.wadsworth.org/testing/lead/index.htm
Serum Zinc Test Results, 0 Event # ROBUST STATISTICAL SUMMARY TARGET VALUE ASSIGNMENT AND STATISTICS SE-06 SE-07 SE-08 SE-09 SE-0 Robust Mean 80 888 65 Robust Standard Deviation Standard Uncertainty RSD (%) 06 5 8.9 0 7 6. 98 8.6 79 6. 6 6 8.9 Number of Sample Measurements 6 6 6 6 6 Acceptable Range: Upper Limit: 658 09 0 880 Lower Limit: 96 57 96 55 90 notes: Results reported as less than the method detection limit are excluded from statistical calculations.
Serum Zinc Test Results, 0 Event # PERFORMANCE OF PARTICIPATING LABORATORIES Lab Code Method SE-06 SE-07 SE-08 SE-09 SE-0 Info Only Target Values: 80 888 65 07 DRC/CC-ICP-MS 56 998 7 90 Info 0 ICP-MS 5 96 8 759 ICP-MS 0 60 00 50 70 7 ICP-MS 6 80 6 95 69 Info 56 ICP-AES/OES 0 890 80 960 70 60 FAAS 80 890 70 850 750 6 ICP-MS 86 708 06 679 5 79 DRC/CC-ICP-MS 0 80 090 80 60 97 ICP-MS 0 80 0 90 670 00 ICP-MS 589 8 89 505 78 Info 06 ICP-MS 0 860 0 760 660 87 FAAS 060 660 900 70 0 9 ICP-MS 87 8 87 68 Info 05 ICP-MS 0 800 000 580 90 ICP-MS 887 557 98 6 Info 5 ICP-MS 800 790 70 9500 860 Info 55 ICP-MS 6 86 0 890 66 57 ICP-MS 00 760 886 790 00 58 ICP-MS 90 850 070 80 60 59 ICP-MS 7 686 08 895 78 6 ICP-MS 50 750 0 780 60 6 ICP-MS 0 850 0 980 690 66 FAAS 9 78 089 98 50 Info 0 DRC/CC-ICP-MS 06 8 5 99 68 Info 57 ICP-AES/OES 606 09 8 9 86 Info 58 FAAS 50 99 8 0 698 Percent satisfactory results for all participants: 87.7 % notes: reported outside upper limit Info only: results included for informational purposes only. reported outside lower limit notes: Results reported as less than the method detection limit are excluded from statistical calculations.
DRC/CC-ICP-MS New York State Department of Health Serum Zinc Test Results, 0 Event # STATISTICAL SUMMARY BY METHOD FAAS ICP-AES/OES ICP-MS All Laboratories SE-06 SE-07 SE-08 SE-09 SE-0 6 5 05 8.8 58 7 08 9. 6 99 07 9.0 877 05 80 7 7.0 955 9 7 76 78 5.9 6 788 9. 6 96 077. 99 7 6 6 0.5 5 8 6. 998 876.6 6 5 6 8 5 8.6 5 888 8.0 7 5 575 90. 787 09 7 580 70 7. 6 6 5.0 notes: Insufficient data for calculation.
Event #, 0 Additional Trace Elements Reported in Serum Participant laboratories reported their analytical results for any additional trace elements (other than Al, Cu, Se and Zn) that are routinely reported so that a more complete characterization can be recorded for these PT materials. Results for additional trace elements are reported here, but no target value is implied nor are any acceptable ranges provided. These data are provided solely for educational and informational purposes. Serum materials were obtained from the Dutch EQA (External Quality Assessment) scheme SKML (Stichting Kwaliteitsbewaking Medische Laboratoria) as part of a global collaborative exercise to harmonize international measurements of Al, Cu, Se and Zn in serum. Additionally, serum pools were spiked with a suite of trace elements at various concentrations including cobalt as CoCl, chromium as CrCl, lithium as LiCl, magnesium as MgCl, manganese as MnCl, thallium as TlNO, and vanadium as VOSO. The serum has been tested and found to be negative for BSE (Bovine Spongiform Encephalopathy), and free of pathogens. The Certificate of Analysis provided by SKML is available upon request. Additional Elements Co, Cr, Li, Mg, Mn, Tl, V Trace Elements PT Program www.wadsworth.org/testing/lead/index.htm
Serum Additional Elements, 0 Event # Page Serum Antimony (µg/l) 7 ICP-MS.9.6. Serum Arsenic (µg/l) 97 DRC/CC-ICP-MS <0.0 <0.0 <0.0 <0.0 <0.0 Serum Barium (µg/l) 7 ICP-MS...7. 97 ICP-MS 5..5. 5.6.5 Serum Beryllium (µg/l) 7 ICP-MS <0.5 <0.5 <0.5 <0.5 <0.5 97 ICP-MS <0. <0. <0. <0. <0. Serum Bismuth (µg/l) 97 ICP-MS..... Serum Cadmium (µg/l) 97 DRC/CC-ICP-MS <0.5 <0.5 <0.5 <0.5 <0.5 Serum Chromium (µg/l) 7 DRC/CC-ICP-MS.0 6.08 9.8.8 7.6 56 DRC/CC-ICP-MS. 5.7 8.7 <.0 6.7 6 DRC/CC-ICP-MS.7 *. 5.6 79 DRC/CC-ICP-MS.8 6. 9.6. 7. 97 DRC/CC-ICP-MS. 5.7 6.6 <.0 6.5 06 DRC/CC-ICP-MS *6.0 *9.0 5 0.0 05 ICP-MS.6 5.9 8.8.0 7. *Omitted Arithmetic mean.5 5.7 50.7 7 SD 0. 0.6 0.9 n 6 6 6 5 7 Serum Cobalt (µg/l) 0 ICP-MS.9 7.6 5.0.0 8.5 7 ICP-MS.66 7.0 9.56.9 8.07 56 DRC/CC-ICP-MS.0 6. 8..5 7. 6 ICP-MS.0 6.5 5.9.6 6.9 79 DRC/CC-ICP-MS.9 7.6 9.0. 8. 97 ICP-MS 5. 7.8 50.. 8.8 06 ICP-MS.0 7.0.0.0 7.0 Arithmetic mean.5 7. 8..9 7.8 SD 0.5 0.6. 0. 0.8 n 7 7 7 7 7
Serum Additional Elements, 0 Event # Page Serum Iodine (µg/l) 7 ICP-MS 5 5.9 5 5 5 6 DRC/CC-ICP-MS 56.0 7.0 6.0 6.0 70.0 97 ICP-MS..8 8. 0.7 9.6 79 ICP-MS 50.0 5.0 5.0 50.0 5.0 Arithmetic mean 8 5 9 9 5 SD 0 6 7 n Serum Iron (µg/l) 57 ICP-AES/OES 68 660 58 68 7 Serum Lead (µg/l) 97 DRC/CC-ICP-MS 0.6 0.7 0.7 0.6 0.6 Serum Lithium (µg/l) 7 ICP-MS 08 866 9 8598 66 Serum Manganese (µg/l) 0 ICP-MS 0.9 05. 06.8 0. 0.7 7 ICP-MS 98.9 89 98.0 98.9 90.7 79 DRC/CC-ICP-MS 98.8 96. 98.7 96.9 97.0 97 DRC/CC-ICP-MS 0. 0. 00 00.5 0.5 ICP-MS 97 0 05 00 05 ICP-MS 97. 0.5 98. 97. 00. Arithmetic mean 00 0 0 00 99 SD 8 5 n 6 6 6 6 6 Serum Mercury (µg/l) 7 ICP-MS <0.00 <0.00 <0.00 <0.00 <0.00 97 ICP-MS <5.0 <5.0 <5.0 <5.0 <5.0 Serum Molybdenum (µg/l) 7 ICP-MS 8.9 8.75 9 8.99 9.5 97 ICP-MS.6.5 0.6.0. 79 DRC/CC-ICP-MS 8.8 9.0 8.8 9. 8.8
Serum Additional Elements, 0 Event # Page Serum Nickel (µg/l) 7 ICP-MS - 0.97 0.78..6 79 DRC/CC-ICP-MS 0.8 0.6 0.6 0.8 0.6 97 ICP-MS <.0 <.0 <.0 <.0 <.0 Serum Platinum (µg/l) 0 ICP-MS 0. 0. 0.6 0.5 0.5 79 ICP-MS <0.0 <0.0 <0.0 <0.0 <0.0 Serum Silver (µg/l) 79 ICP-MS <0. <0. <0. <0. <0. 97 ICP-MS <.0 <.0 <.0 <.0 <.0 Serum Tellurium (µg/l) 7 ICP-MS <0.089 <0.089 <0.089 <0.089 <0.089 97 ICP-MS <.0 <.0 <.0 <.0 <.0 Serum Thallium (µg/l) 97 ICP-MS 5.5. <.0 7.9. Serum Thorium (µg/l) 7 ICP-MS <0.0 <0.0 <0.0 <0.0 <0.0 Serum Tin (µg/l) 7 ICP-MS 0.66 0.66 0.6 0.6-97 ICP-MS <5.0 <5.0 <5.0 <5.0 <5.0 Serum Uranium (µg/l) 7 ICP-MS 0. 0.5 0. 0. 0. Serum Vanadium (µg/l) 7 DRC/CC-ICP-MS 6.8. 0.8 9..9 79 DRC/CC-ICP-MS 6..8 0.8 8..
ATOMIC SPECTROMETRY METHODS New York State Department of Health Trace Elements in Serum METHOD NOTES A- ETAAS-Z (Electrothermal atomic absorption spectrometry with Zeeman background correction) A- ETAAS other (i.e., D, S-H background correction) A- FAAS (Flame atomic absorption spectrometry) A- CV-AAS (Cold vapor atomic absorption spectrometry) A-5 HG-AAS (Hydride generation atomic absorption spectrometry) A-6 AFS (Atomic fluorescence spectrometry) A-7 Other INDUCTIVELY COUPLED PLASMA P- ICP-MS (Inductively coupled plasma - mass spectrometry) P- DRC/CC-ICP-MS (ICP-MS used in the Dynamic Reaction Cell or Collision Cell mode) P- ICP-AES/OES (ICP atomic/optical emission spectrometry) P- HR-ICP-MS (High resolution ICP-MS) P-5 ETV-ICP-MS (Electrothermal vaporization ICP-MS) P-6 ID-ICP-MS (Isotope dilution ICP-MS) P-7 Other ELECTROCHEMICAL METHODS E- ASV (Anodic stripping voltammetry without digestion) E- ASV-LeadCare (Anodic stripping voltammetry using the ESA LeadCare system) E- Fluoride specific electrode E- Other MOLECULAR FLUORIMETRY F- EtOAc (Ethyl acetate-acetic acid extraction method for determination of erythrocyte protoporphyrin) F- Aviv hematofluorometry (for determination of EP at hematocrit 5) F- Helena ZPP (for determination of zinc protoporphyrin in µmol ZPP/mol heme) F- Other OTHER METHODS If your method is not listed in the above list, please describe it briefly.