Danish Diabetes Academy

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Danish Diabetes Academy

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Danish Diabetes Academy Summer School on Diabetes & Metabolism - Scientific Programme 3-6 September, 2018 Sinatur Hotel Gl. Avernæs Helnæsvej 9, DK-5631 Ebberup

Session overview Day 1 Monday September 3th Session I Welcome and Tissue Cross Talk Session II NASH Poster session I Posters no. 1-20 (PI: 01-20) Day 2 Tuesday September 4th Session III Fetal Programming Session IV Precision Medicine Poster session I Posters no. 1-20 (PI: 01-20) Day 3 Wednesday September 5th Session V Metabolism and the Brain Workshop A-E Poster session I Posters no. 21-50 (PI: 21-50) Day 4 Session VI Thursday September 6th Insulin Receptors

Programme Monday September 3 th 09:45 10:30 SESSION I Check-in and mounting of posters WELCOME AND Tissue Cross Talk Chair: Professor Louise Dalgaard, Professor Jørgen Wojtaszewski 10.30 10:45 10:50 11:20 11:20 11:40 11:45 12:15 12:15 12:30 12:30 13:30 Welcome and introduction Professor Torben Hansen, The NNF Center for Basic Metabolism, University of Copenhagen Action of exosomes in type 1 diabetes Professor Claudiane Guay University of Lausanne Role of extracellular vesicles in tissue cross talk during exercise Professor Mark A Febbraio Garvan Institute of Medical Research Lunch break SESSION II Nonalcoholic Steatohepatitis (NASH) Chair: Professor Nils Færgeman, Professor Torben Hansen

13:35 13.55 14:00 14.20 14.25 14.55 14.55 15.15 15:15 15:35 15:35 16:05 16:05 16:25 16:30 17:45 17:45 18:00 18:00 18:25 18:30 19:30 Student presentation: PhD stud. XX, XX University Student presentation (OII-2): XX PhD stud. XX, XX University Fatty liver diseases: The next frontier in clinical hepatology Professor Aleksander Krag Odense University Hospital Coffee break Targeting a Ceramide Double Bond to treat NAFLD/NASH Professor Scott Summers The University of Utah Challenge group work / Get together with your group, introduce yourselves to each other and start discussing the challenge and possible ways to go about the assignment. Short break One-minute poster presentations/ teasers Chair: X Poster session I (PI: 01-17) 19:30 Dinner (challenge groups)

Programme Tuesday September 4 th 07:00 08:30 SESSION III 08:30 09:00 09:00 09:20 09:25 09:55 09:55-10:15 10:15 10:30 10:30 10:50 10:55-11:15 11:15-13:30 Morning exercise and breakfast Fetal programming Chair: Professor Louise Dalgaard, Professor Dorte Møller Jensen Of Mice and Men: epigenomics in type 2 diabetes. Professor and Associate Director Rebecca A Simmons, Center for Research, Reproduction and Women's Health, University of Pennsylvania School of Medicine Metabolic risk and cognitive function in offspring of women with diabetes during pregnancy MD, PhD Tine Dalsgaard Clausen, University of Copenhagen and Nordsjælland Hospital Coffee break Student presentation: PhD stud. XX, X University Student presentation PhD stud., XX University Free time and Lunch break SESSION IV Precision Medicine Chair: Professor Louise Dalgaard, Professor Torben Hansen

13:30-13:50 13:55-14:25 Student presentation (OIV-1): xx XX PhD stud., University The many faces of diabetes - steps towards precision medicine Professor and principal Investigator Leif Groop Lund University 14:25-14:45 14:50-15:20 15:20-15.40 15:40-16:00 16:00 17:00 17:00 18:00 18:00 19:25 How Will Precision Medicine Change the Pharmaceutical/Biotech Industry PhD Joseph Grimsby, MedImmune, LLC Coffee break Challenge group work with mentor feedback Show up at the informed meeting point (the coffee buffet outside the plenum room) where your appointed mentors will be waiting for you to give your group feedback on your thoughts and ideas about your take on a solution to the assigned case or conceptual problem. Time off Plenum debate precision medicine Professeor Leif Groop PhD Joseph Grimsby TBD 19:30 Dinner

Programme Wednesday September 5 th 07:00 08:30 SESSION V Morning exercise and breakfast Metabolism and the Brain Chair: Professor Louise Dalgaard, Professor Dorte Møller Jensen 08:30 09:00 Effects of Human Brain Insulin Sensitivity on Metabolism and Behavior Professor, Dr. Hubert Preißl Institute for Diabetes Research and Metabolic Diseases (IDM) of the Helmholtz Center Munich at the University of Tübingen 09:00-09:20 09:25-09:55 09:55-10:15 10:15:10:4 5 10:45 11:05 11:05 11:25 11:05 11:35 11:55 13:30 13:30 15:30 Dysregulated Metabolism in the Pathogenesis of Alzheimer s Disease: Type 3 Diabetes Professor, Suzanne De La Monte Department of Pathology and Medicine, Pierre Galletti Laboratories Coffee break Student presentation (): XX PhD stud. XX, XX University Student presentation (): PhD stud. XX, XX University One minute presentation Lunch break/ poster lunch Workshops A-E

Workshop A What can metabolomics analyses of beta-cells and islets reveal about islet dysfunction in type 2 diabetes? Professor, Principal Investigator Hindrik Mulder Lund University Workshop B Understanding a bug s life in the fat land Associate Professor, Anandwardhan A. Hardikar The University of Sydney Workshop C Decoding obesity - Long noncoding RNAs and Metabolic Disease Professor Jan-Wilhelm Kornfeld University of Southern Denmark Workshop D Revisiting dogmas of type 2 diabetes-insulin resistance and hyperglycemia: foes or friends? Professor Marc Prentki Department of Medicine, McGill University Workshop E Research Similarities & Differences in Academia versus Industry: Considerations for Starting your own Biotech Company. Vice President Chris Rhodes & PhD Joseph Grimsby Medimmune LLC Workshop F Comparing Apples and Oranges Director Chittaranjan Yajnik KEM Hospital, Pune, India 15:30 16:00 16:00 17:00 17:00 18:30 18:30 19:00 Coffee break Afternoon tea with a brain Network with a senior researcher to talk about their research and career paths. Show up at the meeting point - the coffee buffet outside the plenum room - where an overview of the scheduled professors will be displayed. Finishing your challenge group work and/ or time off Pre-dinner drinks 19:00 Galla dinner

Programme Thursday September 6 07:30 09:30 Morning exercise and breakfast CHALLENGE PRESENTATIONS Chair: XX 09:30 09:40 09:40 09:45 09:45 09:50 09:50 09:55 09:55 10:00 10:00 10:05 10:05 10:10 10:10 10:15 10:15 10:20 10:20 10:25 10:25 10:30 Short introduction to the 5 challenges Team A1: Team A2: Team B1: Team B2: Team C1: Team C2: Team D1: Team D2: Team D3: Team E1: 10:30 Coffee break

10:50 SESSION VI Insulin receptors Chair: Torben Hansen, Nils Færgeman 10:50 11:20 11:20 11:40 11:45 12:30 12:30 12:50 12:50 13:00 (Title TBC) Professor Anders Nykjær, Aarhus University The insulin receptor: structure, mechanism of activation and downstream signalling Professor Pierre De Meyts, Visiting Professor, de Duve Institute Closing remarks 13:00 Lunch-to-go 13:30 Bus transportation to Odense Central Station

Organisers Education Committee Scientific Programme Professor Torben Hansen, University of Copenhagen Professor Jørgen Wojtaszewski, University of Copenhagen Professor Nils Færgeman, University of Southern Denmark Professor Dorte M. Jensen, University of Southern Denmark Professor Louise T. Dalgaard, Roskilde University Professor Peter Vestergaard, Aalborg University Coordinator Education and Networking Coordinator, Helle Elisabeth Lyngborg, Danish Diabetes Academy