Integrating the Best of Traditional Chinese Medicine with Conventional Healthcare

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Integrating the Best of Traditional Chinese Medicine with Conventional Healthcare Justin Wu Director, Hong Kong Institute of Integrative Medicine Associate Dean (Clinical), Faculty of Medicine The Chinese University of Hong Kong

Questions How do we find the BEST of TCM? How do we INTEGRATE with conventional healthcare?

Questions How do we find the BEST of TCM? How do we INTEGRATE with conventional healthcare?

Randomized controlled trials Length of hospitalization Procedure cost Cost-effectiveness analysis underway

Systematic review and meta-analysis Is it a viable solution? Common conclusions Flawed methodology Heterogeneity Publication bias Need of randomized controlled trials

Challenges in searching for the BEST of TCM Lack of high quality evidence Non-English literature Individualized treatment (for both patients and physicians) Heterogeneity in herb combinations

Big Data Project of TCM Web Programming Data Warehouse Metadata Raw Data Summary Data Integration of biomedical databases Text Mining Bioinformatics Analysis R&D Healthcare service Public access

TCM Networks derived by Big Data Analysis Clustering of Core Herb Combinations for Ischemic heart disease TCM management networks for Hypertension Courtesy of Prof. Aiping Lu, HKBU

Big Data: Ultimate solutions for TCM? Strength Powerful tool to identify the commonest TCM combinations for specific disease entities Facilitate TCM innovation with the development of new formula Weakness Popular Effective (e.g. Aqua is present in most TCM formulae) Lack of predictive value for clinical outcome

Big Data Project of TCM Management for Stroke Rehabilitation Big Data Analysis Data mining of TCM Prescription Database Clinical Outcomes (Recurrent stroke, cardiac event, bleeding complications, mortality, etc. Commonest herbal formulae for stroke Patient identifiers CUHK Stroke Registry Pragmatic Trial: Integrative Care Vs Conventional Care

Questions How do we find the BEST of TCM? How do we INTEGRATE with conventional healthcare?

Address the unmet needs of our patients Communication between TCM and Western physicians Combo treatment with monitoring of safety and herb-drug interaction TCM service with good credentials

Hong Kong Institute of Integrative Medicine CUHK-operated Integrative Medical Centre in Prince of Wales Hospital Clinical platform for research, education and practice of integrating TCM with conventional healthcare system

Choose the right diseases Common, chronic or recurrent in nature No effective treatment, marked side effects or high costs in conventional Western medicine Well accepted TCM treatment with high demand in the public

Integrative Model for Low Back Pain Referrals to Orthopaedic clinic from primary care Screening by physiotherapist Early Orthopaedic consultation 1 st Joint consultation by Family Physician and TCM Physician Regular TCM follow up + on-demand FM visits 2 nd Joint consultation in at 4-6 months Discharge back to Primary Care or TCM Clinic

Integrative Model for Stroke Rehabilitation Acute Stroke Unit Stroke Rehabilitation Unit Multidisciplinary team including TCM Physician Stroke rehabilitation programme incorporating TCM treatment Joint consultations and case conferences Discharge to Medical Clinic Herb-Aspirin interaction surveillance programme by School of Pharmacy

Development of Integrative Medical Care Stage 1 Communication, transparency, safety monitoring Risk management, clinical governance and quality assurance Stage 2 Cross validation of Western and TCM diagnosis Pragmatic trials, outcome and cost-effectiveness research Stage 3 Evidence-based, protocol-driven diagnosis and management algorithm supported by pragmatic trials and outcome research Credentialing of training and qualification

Integrating TCM with Modern Conventional Healthcare: Challenges Team building Frontline buy-in Clinical governance Quality assurance Risk and safety management Sharing of patient records Liability Credentialing Reimbursement

Integrating TCM with Modern Conventional Healthcare: Challenges Team building Frontline buy-in Clinical governance Quality assurance Risk and safety management Sharing of patient records Liability Credentialing Reimbursement

Integrating the Best of Traditional Chinese Medicine with Conventional Healthcare New tools to identify the best TCM Big Data Analysis Pragmatic Trial Clinical Outcome and Cost-effectiveness studies Modernized integrative model Patient-centered and physician-friendly Practice of modern healthcare administration Protocol-based approach