21 4 2017 02 08 Chinese Journal of Tissue Engineering Research February 8, 2017 Vol.21, No.4 1 1 2 ( 1 030024 2 030009). [J]. 2017 21(4):609-614. DOI:10.3969/j.issn.2095-4344.2017.04.020 ORCID: 0000-0002-2818-4361() QUS 4 (1) (2) (3) 30 (4) 45 030024 030024 :R318 : :2095-4344 (2017)04-00609-06 2016-12-01 QUS (Langer's lines) 30 45 (11372208)(2013011002-4) Finite element analysis of skin closure stress in different directions Lv Ying 1, n Mei-wen 1, Hou Chun-sheng 2 ( 1 Taiyuan University of Technology, Institute of pplied Mechanics and iomedical Engineering, Taiyuan 030024, Shanxi Province, China; 2 General Hospital of TISCO, urn Center of Shanxi Province, Taiyuan 030009, Shanxi Province, China) bstract CKGROUND: Mechanical factors play an important role in wound healing and scar formation. Finite element model is established to stimulate, analyze and optimize different sutures, which has become a hotspot to guide Lv Ying, Taiyuan University of Technology, Institute of pplied Mechanics and iomedical Engineering, Taiyuan 030024, Shanxi Province, China Corresponding author: n Mei-wen, Doctoral supervisor, Professor, Taiyuan University of Technology, Institute of pplied Mechanics and iomedical Engineering, Taiyuan 030024, Shanxi Province, China ISSN 2095-4344 CN 21-1581/R CODEN: ZLKHH 609
. surgies accurately. OJECTIVE: To analyze the stress distribution of different simple interrupted suturing directions on the skin wound by establishing the skin finite element model, and to provide basic data for the study of scar formation. METHODS: Porcine back skin uniaxial tensile test was performed to provide reference for the mechanical properties of human skin. Orthotropic skin wound model was established using QUS to calculate the stress distribution on the wound in different suturing directions. RESULTS ND CONCLUSION: The anisotropic mechanical properties of skin wound influenced the suture stress significantly. The elastic modulus along the Langer s line was larger than that in the vertical direction. The stress increased orderly in the Langer s line direction, the Langer s line deflected 30, bias Langer s line 45 and vertical Langer s line. These results suggest that the clinical incision should be made along the Langer s line direction. dditionally, the cut at an angle with Langer s line can also reduce the stress of suture. Subject headings: Cicatrix; Keloid; Stress, Mechanical; Finite Element nalysis; Tissue Engineering Funding: the National Natural Science Foundation of China, No. 11372208; the Natural Science Foundation of Shanxi Province, No. 2013011002-4 Cite this article: Lv Y, n MW, Hou CS. Finite element analysis of skin closure stress in different directions. Zhongguo Zuzhi Gongcheng Yanjiu. 2017;21(4):609-614. 0 Introduction [1] [2-7] [8] Candy [9] kaishi [10] [11-13] [14] 40% [15] [16] [17-18] [19-20] [21-22] [23-24] [25] [26] [27-28] [29-31] Z [32] W [33-34] [35] 1.0 2.0 mm [36] 1 Materials and methods 1.1 1.2 4 2 5 1 12 h instron 5544 1.3 1.3.1 610 P.O. ox 10002, Shenyang 110180
. [37] 1 3 Figure 3 ama miniature pig skin samples and experimental equipments instron5544 1 Figure 1 Simple interrupted suture 100 mm 140 mm 0.8 mm 7 30 45 4 4 2 Origin 4 ( X )E1=8.893 3 MPa ( Y)E2=11.76 MPa 1.4 QUS 2 Results (Langer s lines) 30 45 5 12 C D 2 Figure 2 Four kinds of wound models C 30D 45 1.3.2 3 ( )13 ( )6 3 Discussion kaishi [10] 22.4% 32.2% [38] 13 ISSN 2095-4344 CN 21-1581/R CODEN: ZLKHH 611
0.05 0.10 0.30. (MPa) 1.2 1.0 0.8 0.6 0.4 0.2 0 (MPa) 1.2 1.0 0.8 0.6 0.4 0.2 0 4 Figure 4 The linear relevant fitting results of porcine back skin sample data 0 0.10 0.15 0.20 0.25 0.30 0.05 0 0.05 0.15 0.20 0.25 0.35 0.40 5 Figure 5 Calculated results of the incision sutured along the Langer s line Mises 121.8 MPa 128.6 MPa 6 Figure 6 Calculated results of the incision sutured perpendicular to the Langer s line Mises 147.1 MPa 154.3 MPa 7 30 Figure 7 Calculated results of the incision sutured with 30 angle to the Langer s line Mises 132.4 MPa 138.2 MPa 8 45 Figure 8 Calculated results of the incision sutured with 45 angle to the Langer s line Mises 140 MPa 145.7 MPa 612 P.O. ox 10002, Shenyang 110180
. 9 Figure 9 Output pathway of stress in the wound sutured along the Langer s line node 25 node 4 7 10 13 16 19 22 node 10 Mises 9 Figure 10 Mises stress distribution in the wound sutured along the Langer s line Number 1 4 7 10 13 16 19 22 25 3.0 24.2 121.8 107 65.4 95.1 68.3 22.2 3.0 MPa 56.7 MPa 11 Figure 11 Output pathway of stress in the wound sutured perpendicular to the Langer s line node 25 node 4 7 10 13 16 19 22 node 12 Mises 11 Figure 12 Mises stress distribution in the wound sutured perpendicular to the Langer s line Number 1 4 7 10 13 16 19 22 25 3.2 29.8 147.1 134.2 80.8 119.8 79.2 27.1 3.2 MPa 69.4 MPa 13 Figure 13 Distribution of Langer s lines in human body 14 Figure 14 Schematic diagram of simple continuous suture and 8 -shaped suture 8 8 [39] ( ) [40] ( 14) 8 [41] ( 14) Z CNKI 3 ISSN 2095-4344 CN 21-1581/R CODEN: ZLKHH 613
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