SCIENTIFIC SYMPOSIUM FINAL PROGRAM. Therapeutic Strategies in Advanced Parkinson s Disease With Focus on Infusion Therapies

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SCIENTIFIC SYMPOSIUM Therapeutic Strategies in Advanced Parkinson s Disease With Focus on Infusion Therapies 25 th of November 2017 09.00 17.00 Hotel Hilton Am Stadtpark 1, 1030 Vienna/Austria FINAL PROGRAM

FINAL PROGRAM SATURDAY 25 TH OF NOVEMBER 2017 09.00 09.10 Opening 09.10 09.45 Long-term Aspects of Oral Dopamine Agonists and s.c. Apomorphine Prim. Dr. Dieter Volc (Vienna, Austria) 09.45 10.30 Apomorphine injection therapy for Parkinson s Disease Prof. Per Odin, MD, PhD (Bremerhaven, Germany) Scientific Symposium Therapeutic Strategies in Advanced Parkinson s Disease With Focus on Infusion Therapies The medical management of moderate/intermediate and advanced stages of Parkinson s disease (PD) is complex. Patients experience a very good response to Levodopa during early stages of the disease. As the disease progresses, however, the effect of Levodopa starts to wear off. Motor fluctuations occur, characterized by the end-of-dose phenomenon or wearing-off. As such it becomes ever more challenging to achieve a satisfying treatment that successfully counteracts the symptoms of advanced PD while at the same time minimizing side effects. Together with international experts, we will approach current concepts and strategies in advanced Parkinson s disease. The lectures course will provide the theoretical education and practical experience in the management of pump-based treatments for advanced Parkinson s disease. This scientific symposium will grant 10 DFP education points as well as CME credits. (Austria/Germany) and CME Credits (ECMEC s, Europe). EACCME (European Association Council for Continuing Medical Education) is the authorised organization for the accreditation/ certification of Medical Education activities in Europe. The symposium is sponsored by EVER Pharma. 10.30 11.15 Coffee Break 11.15 12.00 Selecting DBS or infusion therapy patients in advanced PD and 5-year follow-up Prof. Angelo Antonini, MD, PhD (Venice/Padua, Italy) 12.00 12.45 Practical management of adverse events related to Apomorphine therapy Prof. Pedro J. García-Ruiz, MD, PhD (Madrid, Spain) 12.45 13.30 Business-Lunch 13.30 14.15 Quality of life in Parkinsons s Disease improved by Apomorphine pump Prof. David Devos (Lille, France) 14.15 15.00 Subcutaneous Apomorphine infusion therapy in advanced PD: long-term follow-up of effectivity, tolerability and patient satisfaction PD Dr. Friederike Sixel-Döring (Kassel, Germany) 15.00 16.30 Discussion & Close-up 16.30 Coffee & Networking Individual departure on Saturday 25 th /Sunday 26 th We hope we will provide valuable information for the treatment of your patients!

SPEAKERS in alphabetical order Prof. Angelo Antonini, MD, PhD Neurology Clinic University Hospital, Padua IRCCS San Camillo, Venice, Italy Angelo Antonini, MD, PhD is Professor of Neurology and director of the Parkinson Unit and operates at the Rehabilitation Hospital San Camillo in Venice and at the Neurology Clinic in Padua. He earned his medical degree from the Università degli Studi di Roma La Sapienza, Rome In November 1990 he completed his neurology training with honors and then undertook a visiting fellowship at the PET Department Paul Scherrer Institute, Villigen, Switzerland before starting in 1991 his PhD in neuroradiology under the supervision of Professor Klaus Leenders. In 1995 he started as Assistant Professor of Neurology at the North Shore Hospital/ New York University hospital where he continued his research on definition of imaging biomarkers of the dopamine system and associated neurodegenerations. He also focused his research on characterization of brain networks in PD using FDG-PET. He received the first award from the National Parkinson Foundation for young researchers in Parkinson s disease. In 1996 he received the Junior Faculty Award and in 1996/97 from the United Parkinson Foundation and Parkinson s Disease Foundation for his research in the field of PD. From November 1997 to end 2009 he worked at the Parkinson Institute in Milan where he coordinated Clinical Research at the Department of Neuroscience and had his academic affiliation at the 2nd Univer sity of Milan (Bicocca). In 2010 he became director of the Parkinson and Movement Disorders Unit at the Research Institute for Neurorehabilitation San Camillo in Venice and is responsible of the Movement Disorders section at Neurology Clinic in Padua. His research focuses on pharmacology of dopaminergic medications, neuroimaging as well as cognitive and behavioral aspects of Parkinson s disease. In addition he is actively involved in the use of continuous infusion of levodopa and apomorphine infu sion as well as subthalamic nucleus deep brain stimulus (STN-DBS) for the treatment of motor fluctuations and dyskinesia of complicated Parkinson patients. Prof. David Devos, MD, PhD Faculty of Medicine & Neurologist University Hospital University of Lille, France David Devos, MD, PhD obtained doctorial degrees in both neurology and neuroscience from the University of Lille, France. Between 2002 and 2010, he worked as a hospital physician in the Department of Neurology and Movement Disorders of the Centre Hospitalier Régional Universitaire de Lille. He is now a professor in medical pharmacology (Lille University, INSERM U1171). His main research interest is in developing new symptomatic and disease-modifying strategies in neurodegenerative diseases such as Parkinson s disease, amyotrophic lateral sclerosis, dementia and cerebellar ataxia. His research is mainly based upon clinical trials but also includes preclinical, translational and other clinical studies in neuropsychopharmacology. Prof. Per Odin, MD, PhD Department of Neurology, the Central Hospital in Bremerhaven, Germany Department of Neurology, Lund University, Sweden Per Odin, MD, PhD is since 2001 head of the department of Neurology at the Central Hospital in Bremerhaven, Germany, since 2013 also Professor of Clinical Neuroscience at the Lund University, Sweden and Consultant in Neurology at the Skåne University Hospital in Lund. After medical school and 5 years of PhD research at Uppsala University, Sweden, he came to Lund in 1987. There he became certified physician 1989 and specialist of Neurology 1993. Since this time his research and clinical focus has been Parkinson s disease and Movement Disorders. He has been performing experimental, translational and clinical research connected to this research area. Presently his focus is non-motor symptoms, continuous dopaminergic stimulation in Parkinson s disease and he is also much involved in projects around cell transplantation and trophic factor treatment for this disease. Apart from his experiences in Sweden, he has now a long experience from neurology and neuroscience in Germany. He has spent 3 years as consultant at the Hannover Medical School (1996-1999), 2 years as national coordinator for the German Parkinson research network Competence Network Parkinson s disease (1999-2001) and since 2001 he is responsible for the department of Neurology at Klinikum-Bremerhaven, Germany. He is chair of the Scandinavian Movement Disorder Society. Dr. Friederike Sixel-Döring, MD Department of Neurology Kassel, Germany Friederike Sixel-Döring, MD, was born in Bonn, Germany in 1958. After medical school from 1977 to 1984 at Philipps-University in Marburg, Germany, she earned her medical licence and doctoral degree of Philipps-University in 1984. In the year 1989 she did her examination as board certified neurologist. She gained experiences as consultant neurologist at Wicker-Klinik in Bad Wildungen, Germany, from 1989 to 2001. Since 2001 she is vice medical director of the Paracelsus-Elena-Klinik in Kassel, Germany. In 2014 she gained her venia legendi and habilitation at the Department of Neurology at the Philipps University in Marburg, Germany. She holds additional qualifications in rehabilitation medicine, as investigator in clinical trials and in sleep medicine. Friederike Sixel-Döring, MD, PhD is member of the German Association of Sleep Medi cine, the World Association of Sleep Medicine, the German Neurologic Society, the Movement Disorder Society and a founding member of the German work-group of Deep Brain Stimulation. Prof. Pedro J. García-Ruiz, MD, PhD Department of Neurology Universidad Autónoma de Madrid, Spain Pedro J. García-Ruiz, MD PhD is at present coordinator of Movement Disorders Unit at Fundacion Jimenez Diaz asn associate Professor of Neurology at Universidad Autonoma de Madrid. He obtained his doctorial degree at the Universidad Autónoma de Madrid in Spain, He worked at the Hospital Clinico San Carlos in the Residency of Neurology in Madrid. Then he undertook a fellowship at the Centre Hospitalier Universitaire de Grenoble for Movement Disorders in France until 1996. He joins scientific memberships including Movement Disorders Society, European Neurological Association, International Neurotoxin Association and Sociedad Española de Neurología. Pedro J. García-Ruiz, MD, PhD holds over 200 publications in the fields of Movement Disorders. He obtained several grants over the last five years and has been coordinator of Movement Disorders Section of Spanish Neurological Society. Chair and Speaker Prim. Dieter Volc, MD Head of Neurology Department & Movement Disorders Center Confraternitaet - Privatklinik, Vienna, Austria Dieter Volc, MD has been involved in various clinical trials and programs in neurogeriatrics, especially with Parkinson s and Alzheimer s disease since 1984. In 1990 he became a coworker of Univ. Prof. Dr. Walther Birkmayer, the first user of L-DOPA therapy for Parkinson s disease. 1993 Dr. Volc founded PROSENEX AmbulatoriumbetriebsgesmbH, a private outpatient facility for neurogeriatric disorders and in 1995 became head of the Neurology Department & Movement Disorders Center at Confraternitaet- Privatklinik Josefstadt. Dr. Volc was responsible for 35 clinical trials in neurological disorders since 1984 as PI, deputy PI or co-investigator, of which 17 studies were focused on Parkinson s disease. Six studies were phase I trials first-in-man/first-of-its-kind. His interest is in all stages of Parkinson s disease with a strong adherence to invasive therapies in advanced stages. He has a strong connection with the patients organizations in both Parkinson s disease and restless legs/willis-ekbom-disease groups where Dr. Volc served as a medical advisor and member of the board.

GENERAL INFORMATION Venue Education This symposium grants accreditation for 10 DFP points (Austria/Germany) and CME credits (ECMEC s, Europe). EACCME (European Association Council for Continuing Medical Education) is the authorised organization for the accreditation/certification of Medical Education activities in Europe. Getting to the Symposium Hotel Hilton Am Stadtpark 1, Vienna/Austria Tel.: +43-1-717000 Fax: +43-1-7130691 E-Mail: info.vienna@hilton.com The Hilton Vienna hotel has a direct airport connection via the city airport train (CAT) which is located opposite of the hotel. Traveling to the Hotel has never been easier: You only need 16 Minutes from Airport to Hotel. Drive time by taxi 20 min. Program The organizers cannot grant liability for any changes according to the program due to external or unforeseen circumstances. Name Badges Participants are kindly requested to wear their name badge all the time. The badge represents admission to the scientific program. Coffee Breaks & Scientific Business Lunch Lunch, coffee, tea, soft drinks are served during breaks free of charge to all participants. Currency The official Austrian currency is EUR. Electricity Electrical current is 220 volts, 50 Hz. Two-prong plugs are standard. Time The time in Austria is CET (Central European Time GMT+1) Mobile Phones Participants are kindly asked to keep their mobile phones in silent mode while attending the scientific sessions. Organizer & Responsibility Medizin Medien Austria GmbH Grünbergstraße 15, 1120 Wien office@medizin-akademie.at www.medizin-medien.at Language The official language is English. Simultaneouse translation will not be provided. Contact: Martina Tschapka Head of Medizin Akademie T +43 1 54600 670 M +43 676 88460670 m.tschapka@medizin-medien.at For further information, please visit: http://medizin-akademie.at/parkinson/

Sponored by EVER Neuro Pharma GmbH Oberburgau 3, 4866 Unterach / Austria www.everpharma.com www.dminecare.com