Deniz Cetin-Sahin, MD, PhD(s) Department of Family Medicine, McGill University

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Which Technology Interventions Reduce Emergency Department Visits and Hospital Admissions From Long- Term Care Facilities? Findings From a Systematic Review Deniz Cetin-Sahin, MD, PhD(s) Department of Family Medicine, McGill University 21 April 2018 Canadian Geriatrics Society Annual Scientific Meeting Montreal, Quebec

Disclosure of Financial Support This program has received financial support from: Donald Berman Maimonides Medical Research Foundation in the form of a research fellowship. The Fonds de recherche du Québec Santé (FRQ-S) in the form of a doctoral training award. This program has received in-kind support from Donald Berman Maimonides Medical Research Foundation in the form of logistics. Potential for conflict of interest: None

Team Members Machelle Wilchesky, PhD (Primary supervisor) Ovidiu Lungu, PhD Matteo Peretti, MSc(c) Genevieve Gore, MLIS Philippe Voyer, RN, PhD Brian Gore, MD, CCFP, Dip Epid Steven Handler, MD, PhD, CMD McGill University, Department of Family Medicine and Division of Geriatric Medicine Donald Berman Maimonides Geriatric Centre McGill University, Centre for Clinical Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital Donald Berman Maimonides Geriatric Centre Université de Montréal, Départment de Psychiatrie McGill University, Department of Family Medicine, Donald Berman Maimonides Geriatric Centre McGill University, Schulich Library of Science and Engineering Faculté des Sciences Infirmières, Université de Laval Donald Berman Maimonides Geriatric Centre University of Pittsburgh School of Medicine, Department of Biomedical Informatics and Division of Geriatric Medicine Clinical Informatics and Long-term Care Health Information Technology, UPMC Senior Communities

Background Knowledge gap Review questions Methods Results Conclusions Outline 4

Background Long-term care facility (LTCF) residents are at high risk of being transferred to acute care (Grabowski et al, 2008) More than 1/3 of the residents visiting emergency departments (ED) are eventually admitted to a hospital (Ackerman et al, 1998) About 2/3 of hospital admissions (HA) are avoidable (Ouslander et al, 2010) Significant adverse outcomes associated with avoidable ED transfers and hospitalizations (Dwyer et al, 2014)

Interventions Aimed At Reducing Potentially Avoidable Acute Care Transfers Wilchesky M, Cetin-Sahin D, Gore G, et al. PROSPERO 2016:CRD42016048128 http://www.crd.york.ac.uk/prospero/display_record.asp?id=crd420160481 28 Complex because they address multi-dimentional reasons for transfers Multi-component Training, human resources, tools, technology

Definition of Technology Information and communication technology used by healthcare organizations for management or delivery of healthcare Adapted from Effective Practice and Organization of Care (EPOC). EPOC taxonomy; 2015.

Knowledge gap Evidence exists regarding feasibility and stakeholder satisfaction (Edirippulige et al, 2013) Lack of evidence for their effectiveness (Edirippulige et al, 2013) Limited number of technologies studied Reduction in acute care transfers has not been studied Most studies are observational and qualitative (Edirippulige et al, 2013)

Review Questions 1. What types of technology interventions exist for LTCF stakeholders in order to reduce acute care transfers in the event of an acute or complex changes in resident health status? 2. What is the effectiveness of these interventions in reducing acute care transfers as compared to usual care?

METHODS

Design: Systematic mixed studies review (Souto et al, 2015) Main inclusion criteria: Interventions Comparison Outcome measures Setting Study methods Language Technology-centered or aided programs, models of care, innovations, or tools Usual care ED visits or hospital admissions Facility-based long-term care (Canadian Healthcare Association) Quantitative and mixed studies English or French

Three-Phase Search Strategy Database search from inception to July 2016 Embase MEDLINE CINAHL Social Work Abstracts PsycINFO The Cochrane Library Ovid Textwords AMED Global Health Health and Psychosocial Instruments Joanna Briggs Institute EBP Database Ovid Healthstar Web of Science Backward and forward citation tracking techniques Grey literature search

Two Independent Reviewers Identification and Selection Process Quality appraisal of selected studies: Mixed Methods Appraisal Tool (MMAT) (Souto et al, 2015) Scored from 0 to 4 Data extraction: Characteristics of studies Descriptions of interventions Evidence of effectiveness

Knowledge synthesis High heterogeneity Most studies reported insufficient quantitative data for inclusion in a random-effects model meta-analysis

RESULTS

Identification and selection results 8,424 records identified through database searching 3,078 additional records 6,526 records after duplicates removed screened based on titles and abstracts 6,382 records excluded 29 additional records identified through other sources Backward citation tracking (4) Forward citation search (22) Grey literature search (3) PRISMA-P 2015 statement (Moher et al, 2015) 144 full text articles were assessed for eligibility 16 studies included in the synthesis 153 articles excluded Not primary studies (10) Not technology interventions (77) Not LTC setting (37) No outcomes of interest (29)

Characteristics of the studies Year: Between 1998 and 2016 Country: USA (4), Australia (3), Canada (2),UK (2), Taiwan (2), China (2), New Zealand (2) Quality MMAT total score: Low scores (0-1) n=4 Other scores (2-4) n=12

Clinical heterogeneity Design Randomized pre-post intervention study Retrospective quasiexperimental study Feasibility pilot study Cluster randomized stepped-wedge trial 2 group matched pre-post prospective cohort study Retrospective pre-post study Intervention Mono vs multi-component Various components other than technology Different stakeholders involved Usual care, population under study: Not consistently defined

Statistical heterogeneity ED visits # of visits # of annual visits # of return visits Proportion of 30 day return visits without hospital admission Hospital Admissions Rate/1,000 resident days # of monthly hospital visit Proportion of 30 day hospital readmissions # of avoidable admissions # of annual admissions following ED visits # of discharge from the ED without admission

Three types of technology 1. Web-based visual system for telemedicine (n=5)* 2. Non-visual tele-coaching (n=7) 3. Health information systems (n=6) * 2 studies also included more than 1 technology type

1. Web-based visual system for telemedicine Definition: Direct provision of a clinical service (diagnosis or management) Videoconferencing Telemedicine carts Exam cameras Digital otoscopes Electronic stethoscopes Dermatoscopes Ophthalmoscopes

1. Web-based visual system for telemedicine Author year Grabowski 2014 Hex 2015 Hsu 2010 Hui 2001 Stern 2014 INTERVENTION Telemedicine for wound care Telemedicine for long-term chronic conditions and people thought to be in the last 12 months of life Taiwan s Telehealth Pilot Project: a tele-consultation infrastructure to link the LTCF to tertiary hospitals Telemedicine to provide geriatric services Enhanced multidisciplinary teams via telemedicine (advanced practice nurses) N (setting) ED visits Effectiveness 11 (6-C; 5-I) -- 4.4% 48 (21-C; 27-I) 14% 5% 3-I -- 25% 1-I 8.8% 10.6% 12 (exposed to both I and C) 30% 20% Hospital admissions

2. Non-visual tele-coaching Definition: Clinical consultation or transfer approval process with experts from outside LTCF Telephone calls e-mails

Author year Boyd 2014 Codde 2010 Hullick 2016 Lee 2002 Sankaran 2010 Street 2015 Stern 2014 2. Non-visual tele-coaching INTERVENTION Residential Aged Care Integration Program (gerontology nurse specialist) An enhanced primary care service (EDbased nurses) The Aged Care Emergency service (EDbased nurses) Care protocol (community nurse) A complex multidisciplinary intervention (Clinical Nurse Specialists and geriatrician) Residential Care In-Reach (specialist practice nurses) Enhanced multidisciplinary teams via telemedicine N (setting) Effectiveness Effectiveness 54 (25-C; 29-I) -- 43% Effectiveness 1-I 15% -- 12 (8-C; 4-I) 45 (assigned) No significant change ~ ~35 % No significant change ~ 1-I -- No significant change ~ No significant change ~ All LTCFs in a region 11% 23.2% 12 (exposed to both I and C) 30% 20%

3. Health information systems Definition: Electronic transfer of clinical information, documents, or secure messaging to either facilitate transfer of clinical data or to alert clinicians regarding resident health status changes

Author year Hsu 2010 Rantz 2015 Yeaman 2015 Joseph 1998 Levy 2008 Lisk 2012 3. Health information systems INTERVENTION Taiwan s Telehealth Pilot Project (tests results were uploaded into computerized physician order entry system) Missouri Quality Initiative intervention (health information exchange system) Health Information Technology (electronic point of care documentation tool that is wallmounted allowing the flow of information from and to acute care) Nurse practitioner-physician teams (on-line scheduling services for specialty consultations and diagnostic tests) Making Advance Planning a Priority (fax to the attending physician indicating that the resident was at high risk for mortality) Regular liaison of consultant geriatricians (email alert system to inform the geriatrician when a resident was admitted to the hospital) N (setting) Effectiveness ED visits Hospital admissions 3-I -- 25% 1-I -- 85% 5-I 71% 21.1% 30-I -- 1-I -- 3-I (Part1) 6-I (Part 2) -- 43% Compared with other LTCFs, 10.4% lower rates Dying in the hospital 39%

CONCLUSIONS

Effectiveness Web-based telemedicine and health information systems - Does visual access to resident and their health records facilitate decision making to keep residents in the facility? - How can we improve these systems? Non-visual tele-coaching ~ - Effect of different kinds of expertise (medical or nursing specialists, allied health professionals) in prompting or preventing decisions for transfers? - Qualitative in-depth studies may explore the reasons

Recommendations Future intervention studies should collect and report standardized quantitative data (e.g. transfer rates per 100 resident-days) to allow assessment of intervention effectiveness in metaanalyses.

Types of technology Several types of technologies are being be used to reduce ED transfers and HAs from LTCFs Potential use of newer technologies (e.g., virtual reality, wearable technology) could be studied

REFERENCES 1. Grabowski DC et al. Predictors of nursing home hospitalization: a review of the literature. Medical care research and review : MCRR. 2008; 65(1): 3-39. 2. Ackermann RJ et al. Emergency Department Use by Nursing Home Residents. Annals of Emergency Medicine Annals of Emergency Medicine. 1998; 31(6): 749-57. 3. Ouslander JG et al. Potentially Avoidable Hospitalizations of Nursing Home Residents: Frequency, Causes, and Costs. J Am Geriatr Soc. 2010; 58(4): 627-35. 4. Dwyer R et al. A systematic review of outcomes following emergency transfer to hospital for residents of aged care facilities. Age Ageing. 2014; 43(6): 759-66. 5. Effective Practice and Organization of Care (EPOC). EPOC taxonomy; 2015. Available at: https://epoc.cochrane.org/epoc-taxonomy 6. Edirippulige et al. A systematic review of telemedicine services for residents in long term care facilities. Journal of Telemedicine and Telecare 2013; 19: 127 132 7. Souto RQ et al. Systematic mixed studies reviews: Updating results on the reliability and efficiency of the mixed methods appraisal tool. Int J Nurs Stud. 2015; 52(1): 500-1. 8. Canadian Healthcare Association. New Directions for Facility-Based Long Term Care. 2009 [cited 20 April 2018]; Available from: http://www.healthcarecan.ca/wpcontent/themes/camyno/assets/document/policydocs/2009/external/en/newdirectionsltc_en.pdf 9. Sandelowski M. What's in a name? Qualitative description revisited. Res Nurs Health. 2010; 33(1): 77-84. 10. Popay J. Moving beyond effectiveness : methodological issues in the synthesis of diverse sources of evidence. London, England: National Institute for Health and Clinical Excellence; 2006. 11. Moher D et al. Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Systematic reviews. 2015; 4(1).

Thank you

Facility-based long-term care American Medical Directors Association s (AMDA) definition Nursing home or skilled nursing facility (NH/SNF) providing care for: Frail elderly patients and younger adults Requiring 24-h nursing and rehabilitation for chronic medical conditions or impaired mental capacity Having significant deficiencies in activities of daily living Canadian Healthcare Association s (CHA) definition NH or facility-based long-term care providing care for: Frail elderly patients and younger adults Unable to remain at home or in a supportive living environment (e.g., assisted living facility) Need health (nursing/medical), social and personal care