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VERTEBRIS cervical we perform innovation we perform innovation Intensive Course 46 th International Training Course for Full-endoscopic Operations of the Lumbar, Thoracic and Cervical Spine January 31 st - February 1 st, 2019 VERTEBRIS thoracic VERTEBRIS VERTEBRIS lumbar stenosis COURSE DIRECTORS Dr. Verapan Kuansongtham Priv.-Doz. Dr. med. habil. Sebastian Ruetten VERTEBRIS denervation VERTEBRIS Full-endoscopic solutions for disc herniations, spinal canal stenosis, sacroiliac and facet joint syndrome ORGANIZERS,, Bangkok, Thailand Chula Soft Cadaver Surgical Training Center, Chulalongkorn University, Bangkok, Thailand Center for Orthopedics and Traumatology of the St. Elisabeth Group - Catholic Hospitals Rhein-Ruhr, St. Anna Hospital Herne/Marien Hospital Herne University Hospital/Marien Hospital Witten, Germany The Bumrungrad Hospital Foundation RIWOspine GmbH Pforzheimer Straße 32 75438 Knittlingen Deutschland Tel.: +49 7043 35-0 info@richard-wolf.com www.richard-wolf.com Distributed by: Berli Jucker Public Company Thailand Tel.: 02-3671 1301-3 www.riwospine.com www.bumrungrad.com

Invitation Dear colleagues, Cervical and lumbar disc herniation is a common problem requiring discectomy. In general, open spinal discectomy is associated with muscle and ligamentum flavum dissection which can cause scaring and long-term side effects. In order to make cervical and lumbar disc surgery minimally invasive, Priv.-Doz. Dr. med. habil. Sebastian Ruetten has developed a Richard wolf endoscope for both cervical and lumbar discectomy. His operative techniques significantly reduce the risks of these potential complications. The endoscopic cervical and lumbar discectomy is another step advance from cervical and lumbar microdiscectomy that is performed with the use of the operating microscope. The surgical visualization by an endoscope is better than with the operating microscope. Because an endoscope can enter into surgical anatomy and has a capability to look around with 25-degree lens unlike the operating microscope that views the surgical site from a distance, endoscopic discectomy requires a smaller incision and less tissue dissection than microscopic discectomy. Obviously, this minimally invasive, less traumatic, endoscopic cervical and lumbar discectomy leads to excellent results, faster recovery, and significant economic saving, which is extremely gratifying for both the patient and the surgeon. This time we include more advanced lecture and workshop table for recess decompression surgery with the new scope. We have accomplished this technique for a couple of years with good results. We will devote ourselves to further development in the field of minimally invasive spine surgery. In this situation, we are very grateful for your participation. We hope that this training course will offer great opportunities for neurosurgeons and orthopedic surgeons to communicate, exchange experiences and upgrade their expertise which would eventually lead to further development and innovation in this field. Message from Chief Executive Officer and Medical Director of Dear colleagues, At Bumrungrad, we strive for professional excellence and innovation in all we do. We participate actively in the advancement of medicine practice through research and education. For Spine Surgery, in June 2011 the has been established at our hospital. In addition, we launched the Asian Full Endospine Training Center in collaboration with St. Anna Hospital Herne and Richard Wolf GmbH at Bumrungrad. This evidenced the recognition of the capabilities and experience of our spine surgeons in advance endoscopic techniques pioneered in Germany. As you may already be aware, Priv.-Doz. Dr. med. habil. Sebastian Ruetten is a world pioneer who invented a special technique for using an endoscope to operate patients with herniated discs and stenosis. In 2008, Dr. Ruetten and Dr. Kuansongtham decided to become partners in training doctors around the world for the full-endoscopic spine and cervical surgery. Each year, they will jointly organize a symposium for full-endoscopic surgery of the lumbar and cervical spine twice a year in Germany (March and September), and once a year in Thailand (around January). Since Thailand is the only training center in Asia, each time we received participants from many countries in this region like Hong Kong, Malaysia, Korea and India. We trust that you will find our symposium even more interesting forum for exchange of knowledge and experiences among doctors with diverse background. Assoc. Prof. Somsak Chaovisitsaree, M.D. Chief Executive Officer and Medical Director Thank you very much. Dr. Verapan Kuansongtham Director of Division of Neurosurgery Department of Surgery Chula Soft Cadaver Surgical Training Center, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand Priv.-Doz. Dr. med. habil. Sebastian Ruetten Head of the Center for Orthopedics and Traumatology of the St. Elisabeth Group - Catholic Hospitals Rhein-Ruhr, St. Anna Hospital Herne/Marien Hospital Herne University Hospital/Marien Hospital Witten, Germany 2

Thursday, January 31 st, 2019 Intensive Course: at Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand 09:00-09:15 h Welcome and introduction V. Kuansongtham, T. Tansatit Cadaver Workshop - Part l 09:30-09:45 h Repetition access techniques Full-endoscopic transforaminal approach of the lumbar spine W. Kesornsak, V. Kuansongtham, S. Ruetten Cadaver Workshop Part ll 13:45-14:00 h Repetition access techniques Full-endoscopic interlaminar approach of the lumbar spine W. Kesornsak, V. Kuansongtham, S. Ruetten 14:00-14:30 h Demonstration of interlaminar access V. Kuansongtham, W. Kesornsak, S. Ruetten 09:45-10:15 h 10:15-12:45 h 12:45-13:45 h Demonstration of transforaminal access V. Kuansongtham, W. Kesornsak, S. Ruetten Practical exercises for participants Module 1: Lumbar spine: Full-endoscopic transforaminal operation Instructors: T. Wattanawong, W. Kesornsak, I. Komonhirun, A. Boongird, P. Predeeprompan, K. Saetia, N. Bumrungtin, W. Mahattanakul, S. Ruetten, D. Goethel Lunch 14:30-16:45 h 16:45-17:00 h Practical exercises for participants Module 1: Lumbar spine: Full-endoscopic operation with posterior approach Instructors: T. Wattanawong, W. Kesornsak, I. Komonhirun, A. Boongird, P. Predeeprompan, K. Saetia, N. Bumrungtin, W. Mahattanakul, S. Ruetten, D. Goethel Closing V. Kuansongtham 4

Friday, February 1 st, 2019 Intensive Course: at, Bangkok, Thailand From 08:00 h Registration 08:30-08:45 h Welcome and introduction S. Chaovisitsaree, V. Kuansongtham, S. Ruetten Lumbar / Thoracic Spine: 09:00-09:30 h The transforaminal full-endoscopic approach in disc herniations Technique and indications of posterolateral to lateral access S. Ruetten 09:30-09:45 h Discussion 09:45-10:30 h Live Operation: Full-endoscopic operation with lateral transforaminal access in a disc herniation V. Kuansongtham, T. Wattanawong Moderators: W. Mahattanakul, R. Arunakul, A. Boongird, W. Kesornsak, S. Ruetten Discussion afterwards 10:30-10:45 h Refreshment 10:45-11:15 h The interlaminar full-endoscopic approach in disc herniations - State of the art, possibilities and limitations W. Kesornsak, V. Kuansongtham, S. Ruetten 11:15-11:30 h Discussion 11:30-12:15 h Live Operation: Full-endoscopic operation with interlaminar access in a disc herniation V. Kuansongtham, I. Komonhirun Moderators: W. Mahattanakul, R. Arunakul, A. Boongird, W. Kesornsak, S. Ruetten Discussion afterwards 12:15-13:15 h 13:15-13:45 h 13:45-14:30 h 14:30-14:45 h 14:45-15:00 h 15:00-15:15 h Cervical Spine: 15:15-15:45 h 15:45-16:00 h 16:00 h Lunch Full-endoscopic decompression in lateral and central stenosis Application of the interlaminar and transforaminal W. Kesornsak, V. Kuansongtham, S. Ruetten Live Operation: Full-endoscopic operation with interlaminar access in lumbar spinal stenosis V. Kuansongtham, T. Wattanawong Moderators: W. Mahattanakul, W. Kesornsak, R. Arunakul, M. Ruangchainikom, S. Ruetten Discussion afterwards Technical aspects of full-endoscopic spinal applications & equipment D. Goethel Discussion Refreshment The full-endoscopic operation of the cervical spine with anteriorand posterior access Possibilities and limitations S. Ruetten Discussion Closing V. Kuansongtham 6

December 17 th, 2018 Tel: +66 (0) 2011 3141 +66 (0) 2011 3133 by 46 th Lecture only February 1 st, 2019 Intensive Course January 31 st - February 1 st, 2019 For attending only lecture on February 1 st, 2019 Intensive Course (max 20 participants) on January 31 st - February 1 st, 2019 10,000 65,000 300 2,000 Direct Deposit Swift Code Payment Currency Bank Name Branch Bank Address A/C No : BKKBTHBK : THB/ USD : Bangkok Bank : Bumrungrad Hospital : 33 Soi 3 Sukumvit Road, Klongtoey Nua, Wattana, Bangkok 10110 : 031-706273-5 BHF. for Spine Surgery Training 8

Speakers/Instructors General Notes Asst. Prof. Dr. Rattalerk Arunakul Orthopedic Surgeon Assoc. Prof. Dr. Atthaporn Boongird* Dr. Narongsak Bumrungtin Orthopedic Surgeon Head of Orthopedic Department Chaiyaphum Hospital Dr. Akira Dezawa Visiting Professor Department of Orthopaedic Surgery Mizonokuchi Hospital, Teikyo University Mr. Dirk Goethel General Manager RIWOspine GmbH Assoc. Prof. Dr. Ake Hansasuta* Dr. Withawin Kesornsak Dr. Ittipol Komonhirun Orthopedic Surgeon Dr. med. Martin Komp Center for Orthopedics and Traumatology of the St. Elisabeth Group - Catholic Hospitals Rhein-Ruhr, St. Anna Hospital Herne/ Marien Hospital Herne University Hospital/ Marien Hospital Witten, Germany Dr. Verapan Kuansongtham* Director of Dr. Wattana Mahattanakul* Dr. Kazuo Ohmori Director Center for Spine Surgery Nippon Kokan Hospital Dr. Pradit Predeeprompan Orthopaedic Surgeon Asst. Prof. Dr. Monchai Ruangchainikom Orthopaedic Surgeon Priv.-Doz. Dr. med. habil. Sebastian Ruetten Center for Orthopedics and Traumatology of the St. Elisabeth Group - Catholic Hospitals Rhein-Ruhr, St. Anna Hospital Herne/ Marien Hospital Herne University Hospital/ Marien Hospital Witten, Germany Asst. Prof. Dr. Kriangsak Saetia* Assoc. Prof. Dr. Thanet Wattanawong Orthopaedic Surgeon ORGANIZERS: 33 Sukhumvit 3 Klongtoey Nua, Wattana Bangkok 10110, Thailand Center for Orthopedics and Traumatology of the St. Elisabeth Group - Catholic Hospitals Rhein-Ruhr, St. Anna Hospital Herne/ Marien Hospital Herne University Hospital/ Marien Hospital Witten, Germany Hospitalstrasse 19 44649 Herne, Germany Chula Soft Cadaver Surgical Training Center 4 th Floor Padtayapat building Faculty of Medicine Chulalongkorn University, Bangkok, Thailand The Bumrungrad Hospital Foundation 33 Sukhumvit 3 Klongtoey Nua, Wattana Bangkok 10110, Thailand CONFERENCE LOCATION: Thursday, January 31 st, 2019 Chula Soft Cadaver Surgical Training Center, 4th Floor Padtayapat building Faculty of Medicine Chulalongkorn University, Bangkok, Thailand see map on page 15 Friday, February 1 st, 2019 21 st Floor, Conference Room,, Bangkok see map on page 15 SCIENTIFIC DIRECTION: Dr. Verapan Kuansongtham 33 Sukhumvit 3 Klongtoey Nua, Wattana Bangkok 10110, Thailand Priv.-Doz. Dr. med. habil. Sebastian Ruetten Dr. med. Martin Komp Center for Orthopedics and Traumatology of the St. Elisabeth Group - Catholic Hospitals Rhein-Ruhr, St. Anna Hospital Herne/ Marien Hospital Herne University Hospital/ Marien Hospital Witten, Germany Hospitalstrasse 19, 44649 Herne, Germany ORGANIZATION OFFICE: Miss Chollada Ruangprach Medical Education Bumrungrad Hospital PCL. 33 Sukhumvit 3 Klongtoey Nua, Wattana Bangkok 10110, Thailand Tel: +66 (0) 2011 3141 Fax: +66 (0) 2011 3133 E-mail: medical.education@bumrungrad.com SUGGESTED HOTEL : Best Western Premier 78 Sukhumvit Soi 1, Klongtoey Nua, Wattana, Bangkok, 10110 Tel: +66 (0) 2256 0677 *Also a member of the Chula Soft Cadaver Surgical Training Center, Chulalongkorn University, Bangkok, Thailand 10 LANGUAGE: All lectures, presentations and discussions will be conducted in ENGLISH..

Klongtoey Nua, Wattana +66 (0) 2066 8888 +66 (0) 2011 3133 BUS: 4, 14, 15, 25, 45, 46, 67, 74, 76, 77, 109, 115, 163, 172, 177 Air Bus: 16, 21, 50, 47, 50, 76, 77, 141, 504, 505, 507, 514, 547 Sky Train (BTS) : Saladeang Station Subway (MRT) : Silom Station Bumrungrad International Tower Chula Soft Cadaver Surgical Training Center 4 th Floor Padtayapat Building, Faculty of Medicine, Chulalongkorn University Tel 02-2564737 1873 Rama 4 Rd. Pathumwan, Bangkok 10330