Interventions that work to prevent falls

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Interventions that work to prevent falls Dr Frances Batchelor Research Fellow/Physiotherapist Director, Health Promotion National Ageing Research Institute

How big a problem What causes a fall? What is a fall? Increased knowledge = better outcomes for your clients What works to prevent falls?

What works in falls and fall injury prevention?

What can you do to reduce your risk of falls: 1. See your doctor / HP If you have a fall have a check up Even if you think it was just an accident If you are feeling unsteady when walking / turning If you are reducing your activities No RCT s, but best practice guidelines (JAGS 2011)

2. Exercise / physical activity Most researched single intervention in falls prevention Majority of research in the community setting NOTE: Exercise programs usually have a range of other benefits as well as falls prevention

Sherrington et al 2008 JAGS. 56: 2234-2243 44 RCTs reviewed on exercise and falls prevention Combined result: exercise is effective Greater effect on falls rate if balance is included (17% reduction vs 10%) Greater effect with 50 hours exercise Need balance/functional strength, moderate intensity Sherrington et al 2008 JAGS. 56: 2234-2243

Overall effect of exercise: RR 0.83 (95%CI 0.75 0.91) Sherrington et al 2008

Sherrington et al 2011 Overall effect of exercise: IRR 0.84 (95%CI 0.77 0.91)

What works? A selection of effective exercise programs: Stay Safe, Stay Active (Barnett et al, 2003) The Otago Exercise Programme (Campbell, Gardner) Erlangen Fitness intervention (Freiberger et al, 2007) Tai Chi and modified Tai Chi (Li et al, 2005; Voukelatos et al, 2007; Wolf et al 1996) Falls Management Exercise (FaME) (Skelton et al, 2005)

What doesn t work? Low intensity exercise Only one type of exercise?walking At risk populations e.g. stroke, cognitive impariment high risk of falls but limited evidence on effective interventions

OTAGO EXERCISE PROGRAMME Designed specifically to prevent falls in community dwellingolder adults Includes strength, balance components + walking program Progressive, individually tailored home exercise

OEP 30 minutes exercise 3 x per week Walking 2 x per week Ankle cuff weights for resistance 4-5 home visits Record exercise in diary Phone calls each month between visits

OTAGO Balance exercises

Evidence Meta-analyses Thomas, S., Mackintosh, S., & Halbert, J. (2010). Does the 'Otago exercise programme' reduce mortality and falls in older adults? A systematic review and meta-analysis. Age and Ageing, 39, 681-687. 7 studies, overall the OEP significantly reduced falls rates by 32% Robertson, M. C., Campbell, A. J., Gardner, M. M., & Devlin, N. (2002). Preventing injuries in older people by preventing falls: A meta-analysis of individual-level data. JAGS, 50, 905-911. 4 studies, overall the OEP significantly reduced falls rates by 35%; equally effective in men and women; most effective in reducing injurious falls in those 80+

Where to get it. http://www.acc.co.nz/prd_ext_csmp/group s/external_providers/documents/publications _promotion/prd_ctrb118334.pdf Another version: http://www.laterlifetraining.co.uk/homeexercise-booklets-free-to-download/

Another type of approach Nijmegen Falls Prevention Program Gait, co-ordination, obstacle crossing, uneven surfaces, dual tasks, visual constraint, falling practice, simulated crowded environment, walking to music Education: simulation of dangerous fall situations; physical activity Weerdesteyn et al Gerontology 2006

NFPP Weerdesteyn et al, Gerontology 2006 N = 113 Community dwelling 2 x 1.5 hr sessions weekly, 5 weeks Pre-post design with control group Falls 46% reduction in intervention group, no difference in controls Smulders et al, Arch Phys Med Rehab 2010 N = 96 History of falls/osteoporosis 11 sessions, 5.5 weeks RCT Falling techniques modified Fall rate 39% lower in the intervention group after 1 year.

Another approach Lifestyle Integrated Functional Exercise (LiFE) Strength & balance embedded into everyday activities 3 arm study LiFE Structured ex Gentle ex (control) 31% reduction in the rate of falls for LiFE Clemson et al, BMJ 2012

Another effective approach Emile Jaques-Lacroze Multi-task exercise program performed to the rhythm of piano music Walking in time to music, then more complex movements including footwork 6 month program 1 hour / week class Avoid additional ex at home Trombetti et al 2011

N = 134 Trombetti et al, 2011 Intervention group had fewer falls 54% reduction in falls rates in intervention group (IRR 0.46, 95%CI 0.27 to 0.79) 39% reduction in proportion of fallers in intervention group (RR 0.61, 95% CI 0.39 to 0.96)

Principles for exercise prescription Strength training 8-10 reps before fatigue Balance training less clear time limit for static tasks? Number of saves Walking dosage for falls prevention unclear

Top tip People can do more than first impressions indicate

What can you do to reduce your risk of falls: 3. Medication review COCHRANE 2012: Gradual withdrawal of psychotropic medications reduced rate of falls. A prescribing modification programme for primary care physicians significantly reduced risk of falling.. Keep medications to the minimum Have medications reviewed by your doctor Try to avoid / minimise use of sleeping tablets, anti anxiety tablets etc Largest effect of any falls prevention study involved weaning people off psychotropic medications: Campbell et al 1999

What can you do to reduce your risk of falls: 4. Vision check COCHRANE 2012: First eye cataract surgery reduced the rate of falls in women but second eye cataract surgery did not... Regular vision review Cataract surgery First eye effective Bifocals can be problematic but single vision lenses for active people only

Haran et al 2010, BMJ: 340:c2265

What can you do to reduce your risk of falls: 5. Home safety COCHRANE 2012: Home safety interventions reduced rate of falls and risk of falling particularly in reducing falls rates in participants at higher risk of falling these interventions appear to be more effective when delivered by an occupational therapist. An anti-slip shoe device worn in icy conditions can reduce falls. Removing environmental hazards will reduce risk of falls If having falls should have an occupational therapy home assessment

Environmental safety: Home falls risk assessment & modification commonly used Cumming et al 1999, JAGS: RCT identifying significant reduction in falls rates for OT home visit / environmental assessment / behaviour risk modification IN AT RISK GROUP ONLY NB: falls reduced at home and away from home

Cumming et al 1999 Modification % of homes recommended Adherence at 12 months Mats/rugs 48% 49% Change footwear 24% 54% Use non-slip bathmat 21% 75% Change behaviour, improve safety 15% 60% Use light at night 13% 58% Add rail to stairs 12% 19% Move electrical cords 12% 67%

What can you do to reduce your risk of falls and fall injuries: Vitamin D and calcium Many older people have low levels of vitamin D Main sources of vitamin D are: Sunlight (approx 20 min/day) Some foods (eg sardines) Supplements Vitamin D and calcium together have been shown to reduce fractures and falls (in high risk samples (residential care)

Effect of vitamin D on falls COCHRANE 2012: Taking vitamin D supplements with or without calcium probably does not reduce falls, except in people who have lower levels of vitamin D in the blood at enrolment. Complex series of studies to interpret because of: different types of vitamin D (D2 and D3) different dosages different samples in terms of vit D deficiency supplementation of vitamin D with/without calcium outcomes of fractures as well as falls a more recent study showed increase in falls & fractures with yearly dose of 500,000 IU (Sanders et al 2010, JAMA)

Multifactorial interventions (after assessment) COCHRANE 2012: Multifactorial interventions consist of more than one main category of intervention and participants receive different combinations of the interventions based on an individual assessment to identify potential risk factors for falling. Multifactorial interventions reduce the rate of falls but not the risk of falling.

Luck et al 2013, Clin Int Aging RCT with falls follow-up for 12 months (retrospective) N = 230, 80+ years Intervention: Multidimensional geriatric assessment Multidisciplinary case conference, identify risk factors, recommend interventions 3 home visits focusing on falls prevention strategies including education Results: IRR 0.32 (95% CI 0.22-0.49)

Other interventions Foot exercises and orthotics for those with foot pain (Spink et al, 2011): signifcant decrease in falls Falls after stroke: no RCTs showing effect apart from vit D in residential care for women (Batchelor et al, 2010)

Falls prevention in the community setting SINGLE INTERVENTIONS (RCT evidence) Exercise Multi-component group Multi-component home exercise Tai chi for risk of falling vitamin D?for people with lower levels Change to single vision lenses for those active outdoors (worse for those undertaking little activity) cataract extraction COCHRANE REVIEW: Gillespie et al, 2012

What can you do to reduce your risk of falls: 2. Exercise COCHRANE 2012: Multi-component (combination of two or more categories of exercise) exercise classes significantly reduced rate of falls and risk of falling, as did multiple-component home-based exercise. Tai chi significantly reduced the risk of falling.and appears to be more effective in people who are not at high risk of falling.

Falls prevention in the community setting SINGLE INTERVENTIONS (RCT evidence) Comprehensive prescriber modification program/ psychotropic medication withdrawal Home safety assessment/modification Pacemakers for carotid sinus hypersensitivity Anti-slip shoe device! COCHRANE REVIEW: Gillespie et al, 2012

Falls prevention in the community setting MULTIPLE INTERVENTIONS Foot exercises and podiatry for people with foot pain (rate of falls) MULTIFACTORIAL INTERVENTIONS based on indivualised falls risk assessment reduce the rate of falls, but not risk COCHRANE REVIEW: Gillespie et al, 2012

Other interventions? Safe footwear Education Change gait aid Nutrition Treat incontinence Treat postural hypotension

What works in to prevent falls in residential care? Systematic review and meta-analyses Cochrane Review: Interventions for preventing falls in older people in nursing care facilities and hospitals (Cameron et al 2010, updated 2012) Strategies to prevent falls and fractures in hospitals and care homes and effect of cognitive impairment: systematic review and meta-analyses (Oliver et al 2007) Randomised trials Covering a range of intervention types

1. Education targeting staff, residents, family commonly used most commonly target staff (cf community) Few RCT s with falls/injuries as outcome

Falls prevention in residential care: Staff education Bouwen et al, 2009: Cluster randomised controlled trial 80% of intervention group and 70% of control group had MMSE<23 Intervention nurses from intervention facilities received falls prevention training (limited detail, but maximum reach, post fall analysis and management) Significant reduction in falls after adjusting for institution and baseline results

Falls prevention in residential care: Staff education Cox et al 2008: Care homes in UK randomised to receive intervention at start or 12 months later Primary aim # prevention, falls as secondary outcome ½ day Education, STRATIFY falls risk assessment to managers, nurses, health care assistants. NO difference in fall rate or fracture rate

Education kits VQC online education: http://www.health.vic.gov.au/qualitycouncil/fall sprevention/index.htm Preventing falls in the care home: http://www.medicaleducation.co.uk/free.html

2. Exercise commonly utilised (USA - 96% of settings offer some form of exercise) wide variation in type: group exercise classes, seated ex, Tai Chi individual sessions with a physiotherapist supervised walking activity / leisure pursuits flexibility single leg standing!

Cochrane review: There is no evidence that [ ] interventions targeting single risk factors reduce falls and this includes exercise interventions Cochrane review update: Cameron et al, 2010

Exercise Functional Incidental Training (FIT): Schnelle et al 2002, 2003; Ouslander N = 190 Exercise linked to continence care Walking/repeat sit-to-stands Upper body resistance training when in bed 5 days/wk, every 2 hrs; 32 weeks Significant reduction in fallers, not in fall rate

Exercise Balance training on a force platform: Sihvoven et al, 2004 Gait, balance and coordination exercises 3 sessions per week 20-30 mins, 4 weeks Small sample, n = 28 Significant reduction in falls risk, not in rate

Exercise Shimada, 2004 Perturbed gait exercises on treadmill gait, balance, co-ordination, endurance Small sample size, n = 32 6 months, 600 minutes in total Non significant reduction in falls? Results from pilot study inconsistent

Exercise RCT of multifactorial intervention: Dyer et al, 2004 group (multi-component) exercises 3x weekly run by physio Balance, gait & strength, weights, theraband Flexibility & endurance Linked to function Results: 45% (non significant) reduction in falls; Compliance an issue (59%)

Exercise Faber 2006 N = 238 RCT of 15 facilities 2 intervention types, + usual care Functional Walking exs, 1 session/wk for 4 weeks then 2 sessions for 16 weeks OR 3D balance based on Tai Chi as above Results: falls higher in FW than IB/control not sig.

3. Environmental safety commonly used range of strategies utilised no published RCT s evaluating effect on falls in isolation treaded slippers introduced resulting in marked reduction in falls due to slips in urine (Meddaugh et al,1996)

Use of environmental audits Have been used as part of successful multifactorial interventions in residential care Need to consider: Individual environment General environment

Audit tools Audit tools: http://www.health.vic.gov.au/agedcare/m aintaining/falls_dev/downloads/b2c(1)%2 0Environmental%20audit.pdf https://www.cshisc.com.au/docs/upload/ HACC- 05%20Falls%20Prevention%20Environmen tal%20audit.pdf

4. Clinical assessment a) Medical screen no single intervention RCT s published evaluating medical screen with falls rate as an outcome As part of multifactorial interventions: Two studies resulting in significant reduction in falls / fallers (Dyer et al, 2004; Jensen et al, 2002)

4. Clinical assessment b) Medication review Clinical medication review by pharmacist and recommendations to GP Significantly reduced falls (Zermansky et al, 2006) No significant effect in the study by Crotty. NB Community setting High rate of use of psychotropic medications Largest effect in reducing falls related to weaning patients off psychotropic medications (Campbell et al, 1999)

5. Multiple strategy (targeted and untargeted) Successful interventions based on well designed studies (randomised trials): multi-factorial interventions based on falls risk assessment (Jensen et al, 2002/2003) Staff education, environmental modification, strength balance & mobility exercises, supply and repair of walking aids & wheelchairs, changes in medication, hip protectors, post fall problem solving conference multi-factorial interventions without falls risk assessment (Becker et al, 2003) Staff training, monthly feedback of falls data, resident information sessions, environmental assessments, group exercise programs, hip protectors multi-factorial interventions without falls risk assessment (Dyer et al, 2004) Staff training, group exercise program, medical reviews, environmental modification, optician and podiatry review if required NOTE: each of these studies included residents with cognitive impairment

6. Vitamin D supplementation RCTs examine effects of vit D with/without calcium in comparison to placebo/calcium only Vit D2/3 oral Possible differences depending on serum vitamin D levels

Effective interventions to reduce fractures

Electronic monitoring and alarms Limited RCT evidence -?none in residential care Shorr et al (2012) education and training to increase use of bed/chair alarms in hospital Found increase in use of alarms but NO change in falls NB Bressler et al (2011) : found a reduction in falls after eliminating alarms in dementia care facility!!

Other interventions. Consider interventions effective in communitydwelling older people Podiatry Nutrition Electronic monitoring/alarms Exergaming? Aromatherapy

Falls and injury prevention: what works in hospitals? Acute setting - orthopaedic ward post femoral neck fracture surgery: comprehensive geriatric assessment and management 1, including medication review (RCT): significant reduction in fall rate, proportion of fallers, proportion of fallers with injuries; NB whole-ward approach 1 Stenvall 2007;

Falls and injury prevention: what works? Mixed settings (acute and sub-acute): Nursing care plan 1 based on falls risk factor screen, including guidelines for managing identified risk factors: decrease in falls, no change in injuries (NB matched ward design) 1 Healey 2004; Vision Medications Lying/standing BP Urine ward test Mobility Environment Risk/benefit analysis of bedrails

Falls and injury prevention: what works? Mixed settings (acute and sub-acute): Falls prevention education 1 using DVD/written education ± health professional follow-up: reduced falls in cognitively intact older patients but increased injurious falls in cognitively impaired patients; Sub-acute Multi-factorial 2 with targeted intervention: significant decrease in falls, 30% reduction in falls 1 Haines 2010; 2 Haines 2004 Multidisciplinary falls risk assessment Falls risk alert card Brochure Exercise Education Hip protectors

Mixed/unclear/no evidence Low-low beds no effect 1 vs dose response 2 Exercise effective as part of multi-factorial intervention vs no effect as single intervention Multifactorial approaches - no effect 3 vs effect 4,5 Alarm systems Wrist bands no effect 6 1 Haines 2010; 2 Barker 2012; 3 Cumming 2007; 4 Haines 2004; 5 Stenvall 2007; 6 Mayo 1994

Other considerations Interventions in residential care need to be different to acute/sub-acute 1 Vitamin D Comprehensive geriatric assessment Multi-factorial with exercise Consider interventions effective in community-dwelling older people for community-based services e.g. exercise, multi-factorial approaches, environmental modification 2 What happens after discharge? 15-30% at risk falling within 1 month of discharge from hospital 3,4 1 Cameron 2010; 2 Gillespie 2009; 3 Mahoney 2000; 4 Batchelor 2012

Take home messages Falls and fall-related injury can be prevented This requires a multidisciplinary effort Each patient needs an individualised plan