Resuscitation in Special Situations what s new

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Resuscitation in Special Situations what s new Asc. Prof. Dr. Serkan Şener Acıbadem University, School of Medicine Department of Emergency Medicine Acıbadem Ankara Hospital

Objectives To understand the unique considerations involved in the common special resuscitation situations. To be able to modify resuscitation efforts for special situations.

Erişkin Yaşam Zinciri Immediate recognition and activation of emergency response system Early cardiopulmonary resuscitation (CPR) Early defibrillation Effective advanced life support (ACLS) Integrated post cardiac arrest care

Pediatrik Yaşam Zinciri Prevention Early cardiopulmonary resuscitation (CPR) Prompt access to the emergency response system Rapid pediatric advanced life support (PALS) Integrated post cardiac arrest care

Exceptions Patients who benefit form early airway management and CPR; < 8 y Trauma Toxic ingestions Drowning

Special Situations Asthma Anaphylaxis Pregnancy Morbid Obesity Pulmonary Embolism (PE) Electrolyte Imbalance Ingestion of Toxic Substances Trauma Accidental Hypothermia Avalanche Drowning Electric Shock/Lightning strike Percutaneous Coronary Intervention Cardiac Tamponade Cardiac Surgery

Special Situations Asthma Anaphylaxis Pregnancy Morbid Obesity Pulmonary Embolism (PE) Electrolyte Imbalance Ingestion of Toxic Substances Trauma Accidental Hypothermia Avalanche Drowning Electric Shock/Lightning strike Percutaneous Coronary Intervention Cardiac Tamponade Cardiac Surgery

Accidental Hypothemia Core temperature measurement Standard thermometers (not below 35) Tympanic Rectal Urine bladder

Accidental Hypothermia Classification Mild 35-32 C Moderate 32-30 C Severe < 30 C

ECG in hypothermia (Osborn = J wave)

CPR Modifications in Hypothemia Begin CPR without delay More force is needed to compress the chest wall sufficiently ( muscle rigidity) The efficacy of most medications is temperature dependent (> 30 C) Avoid pharmacologic manipulation of pulse and blood pressure (> 30 C) Do not quit CPR until the patient rewarmed

Defibrillation The temperature at which defibrillation should first be attempted in the severely hypothermic patient and the number of defibrillation attempts that should be made have not been established. After first 3 shocks, postpone next shocks until > 30 C Defibrillation attempts are usually unsuccessful until the core temperature is well above 30 C Incagnoli P, Bourgeois B, Teboul A, Laborie JM. Resuscitation from accidental hypothermia of 22 degrees C with circulatory arrest: importance of prehospital management Ann Fr Anesth Reanim. 2006;25:535 538.

Rewarming Recommended rewarming rates are between 0.5 to 2 C/hr Passive External Rewarming Active Rewarming: Active External Rewarming Active Core Rewarming

Passive Rewarming Moderate (30 C to 32 C) Hypothermia with a perfusing rhythm Wear off the cold and wet clothes Cover with blankets Increase the room temperature

Passive Rewarming

Indications For Active Rewarming Moderate to severe hypothermia (< 32 C) Cardiovascular instability (cardiac arrest) Inadequate rate or failure to rewarm Endocrinologic insufficiency Traumatic or toxicologic peripheral vasodilation Secondary hypothermia impairing thermoregulation

Active Rewarming Tecniques Alternative effective core rewarming techniques: Warm-water lavage of the pleural, peritoneal, gastric and urine bladder cavity (43 C) Extracorporeal blood warming with partial bypass(ecmo) Adjunctive core rewarming techniques also include warmed IV or intraosseous (IO) fluid (43 C) Humidified oxygen

Extracorporeal blood warming with bypass (ECMO)

After ROSC According to standard postarrest guidelines patients should continue to be warmed to a goal temperature of approximately 32 to 34 C to induce hypothermia is appropriate.

CPR in Pregnancy Treatable causes of pregnancy:

Class I interventions Give 100% oxygen. Establish intravenous (IV) access above the diaphragm. Assess for hypotension; maternal hypotension that warrants therapy has been defined as a systolic blood pressure 100 mmhg or 80% of baseline. In the patient who is not in arrest, both crystalloid and colloid solutions have been shown to increase preload.

CPR in pregnancy CPR interventions aim to rescue always FIRST the mother. Standard ACLS algorithms require no modification. ACLS / ATLS medications does not change. No need to adjust resuscitative drug doses

To prevent cardiac arrest Place the patient in the full left-lateral position to relieve possible compression of the inferior vena cava. Maternal aortocaval compression can occur for singleton pregnancies at 20 weeks of gestational age

Uterine obstruction of venous return can produce hypotension and may precipitate arrest

Left lateral tilt position Difficult to apply chest compression

ALTERNATIVE TECHNIQUE Uterine displacement in supine position Two hand technique One hand technique

ACLS Modifications A- Airway Aspiration risk Early intubation & cricoid pressure Laryngeal sweling Small bore tube (0,5-1 mm ) Hypoxia risk Preoxygenation B- Breathing Oxygen demand hypoxia risk Functional residual capacity faster desaturation Elevated diaphram ventilation volume

Pregnant Prearrest On Magnesium Treatment Patients recieving magnesium treatment (eclampsia) before cardiac arrest should be applied IV / IO 10 ml 10% calcium chloride 30 ml 10% calcium gluconate

Perimortem Cesarean Maternal hypotension can result in reduced placental perfusion. Preparation for emergent cesarean delivery should be made while resuscitating. Code team (emergency physician, gynecologist, neonatalogist, anesthesiologist and intensivist) should be paged.

Perimortem Cesarean The rescue team is not required to wait 5 minutes before initiating emergency hysterotomy, obvious nonsurvivable injury, Maternal prognosis is grave and resuscitative efforts appear futile Especially if the fetus is viable. If emergency cesarean section cannot be performed by the 5-minute mark, it may be advisable to prepare to evacuate the uterus while the resuscitation continues.

Drowning The process of experiencing respiratory impairment from submersion / immersion in liquid. Immersion = to be covered in water Submersion = the whole body under water Idris AH, Berg RA, Bierens 2nd J, International et al. Recommended Emergency guidelines for uniform reporting of data from drowning: The Medicine "Utstein Symposium Style". Resuscitation 2003; 59:45-57.

Drowning Process Airway under surface with voluntary breath holding Laryngospasm Hypercarbia, hypoxia, metabolic acidosis Decrease in level of consciousness, relaxation larynx Aspiration of liquid The most important predictor of survival

If water temperature is warmer than 6 C, survival / resuscitation is extremely unlikely if submerged longer than 30 min If water temperature is 6 C or below, survival / resuscitation is extremely unlikely if submerged longer than 90 min Claesson A. Characteristics of lifesaving from drowning as reported by the Swedish Fire and Rescue Services. Resuscitation 2012;83:1072 7. Wanscher. Outcome of accidental hypothermia with or without circulatory arrest. Experience from the Danish Præstø Fjord boating accident. Resuscitation 2012;83:1078 84.

Salt vs Fresh Water Extensive data from animal studies and human case series have shown that, irrespective of the tonicity of the inhaled fluid, the predominant pathophysiological process is hypoxaemia, driven by surfactant wash-out and dysfunction, alveolar collapse, atelectasis and intrapulmonary shunting. Small differences in electrolyte disturbance are rarely of any clinical relevance and do not usually require treatment.

Drowning Outcomes Victim can be rescued in any step of the drowning process and the results are: Death Morbidity Not morbidity

Treatment Prehospital Modifications BLS CPR (initiate ventilation in water if possible) ABC not CAB No benefit of Heimlich maneuver Prevent hypothermia Cervical collar not needed if no trauma (cervical injury incidence only 0.5%)

Treatment Hospital Modifications Pulmonary support ABG, electrolyte Intubate alert victims if pulmonary function impaired (signs of acute lung injury PaO 2 /FiO 2 <300 mmhg ) Use of surfactant, ECMO, NO2 needs more evidence CPAP or PEEP 10 cmh₂o for best SaO₂with lowest Prophylactic antibiotics?? No steroids FiO₂