Curriculum Vitae Franklin Naarendorp

Curriculum Vitae Franklin Naarendorp Education 1987 PhD in Psychology City University of New York, New York, NY 1985 Master of Philosophy City University of New York, New York, NY 1977 Doctoral Degree (Doctorandus) in Psychology (with Psychopathology and Philosophy) University of Amsterdam, The Netherlands 1973 Candidate Diploma in General Psychology University of Groningen, Groningen, The Netherlands Research and professional experience Resident Psychologist National Psychiatric Institute Sept '77-Aug '82 Paramaribo, Suriname Adjunct Lecturer Dept. of Psychology Sept '84-May '87 Queens College, CUNY, New York Lecturer Dept. of Psychology Sept '90-May '91 University of Michigan, Ann Arbor Post-doctoral Fellow Dept. of Ophthalmology Oct '87-Mar '92 University of Michigan, Ann Arbor Assistant Professor Dept. of Psychology Sept. '92- Sept '98 Northeastern University, Boston Associate Professor Dept. of Psychology Sept. '98- present Northeastern University, Boston Visiting Research Scientist Dept. of Ophthalmology Sept. 99- Aug 00 University of Pennsylvania Research interests The neural basis of night vision: 1) psychophysics of human night vision 2) electroretinography of the rodent rod system. 3) mouse visual psychophysics. Dissertation Naarendorp F. (1987) The effects of long term and short term adaptation on cone-mediated vision. City University of New York, New York.

Membership Professional Organizations Association for Research in Vision and Ophthalmology Society for Neuroscience Occasional Journal reviewer Trends in Neurosciences Ophthalmology (American Academy of Ophthalmology) Journal of the Optical Society of America Visual Neuroscience Vision Research Documenta Ophthalmologica Experimental Eye Research Investigative Ophthalmology and Visual Science Optometry and Vision Science Occasional Grant Reviewer: National Science Foundation Review Panelist: National Science Foundation: Sensory Systems and Sensorimotor Integration Funding completed: Northeastern University Research and Development Fund, 1996 1997: $ 8,650 National Science Foundation, Grant 9604206: Rod Retinal Pathways and Scotopic Visual Function, 1997 2000: $ 204,925 Northeastern University Research and Development Fund, 2004 2005: $ 6,000 Subcontract under NIH/NEI Grant (No. 1 R01 EY14057) to Boston University, PI Mark Bitensky, 2002 2005: Regulation of Light Sensitivity by Phosducin and 14-3-3 at the Rod Synapse: $ 135,000. Northeastern University ENHANCE Grant, Office of the Provost, 2008-2009: $ 15,000 Foundation for Fighting Blindness (PI: L. Hedstrom), Transgenic Mouse Models of RP10 Retinitis Pigmentosa Role: PI on Subcontract. Project Period: 2009 2012 Pending application: National Institutes of Health- National Eye Institute. Genetic Basis for Vision Loss in Complete CSNB: Patients and Models: PI Neal Peachey, Cleveland Clinc Lerner College of Medicine. Role: PI on Subcontract. Project Period: 2013 2016. Consultancy Consultant, psychophysics of mouse dark adaptation (2009-2012). Grant EY 02660: Mechanisms of Visual Transduction. (PI: Edward N. Pugh Jr.) Service I serve on a regular basis on Departmental Committees. I am committed to help increase the participation of minority students in scientific research

Publications Akula JD, Esdaille TM, Caffé AR, Naarendorp F. (2011) The scotopic electroretinogram of the sugar glider related to histological features of its retina. Journal of Comparative Physiology A, 197, 1043-1054. Naarendorp F, Esdaille TM, Banden SM, Andrews-Labenski J, Gross OP, Pugh EN Jr. (2010) Dark light, rod saturation, and the absolute and incremental sensitivity of mouse cone vision. Journal of Neuroscience, 30, 12495-12507. Akula J. Lyubarsky AL, Naarendorp F (2003) The identity and sensitivity of the cones driving the b-wave of the rat electroretinogram. Visual Neuroscience, 20, 109-117. Lyubarsky AL, Chen C-K, Naarendorp F, Zhang X, Wensel T, Simon MI & Pugh Jr. EN (2001). RGS9-1 is required for normal inactivation of mouse cone phototransduction. Molecular Vision, 7, 71-78. Naarendorp F., Sato Y., Cajdric A. & Hubbard N.P. (2001). Absolute and Relative Sensitivity of the Scotopic System of Rat: Electroretinography and Behavior. Visual Neuroscience, 18, 641-656. Naarendorp F. & Williams G. E. (1999) The d-wave of the rod ERG of rat originates in the cone pathway. Visual Neuroscience, 16, 91-105. Naarendorp F., Rice K. S. & Sieving P. A. (1996) Summation of rod and S-cone signals at threshold in human observers. Vision Research, 17, 2681-2688. Sieving P.A., Richards J.E., Naarendorp F., Bingham E.L., Scott K. & Alpern M. (1995). Dark light: Model for night-blindness from the human Gly90 ---> Asp mutation. Proceedings of the National Academy of Sciences,USA, 92, 880-884. Naarendorp F., Kortick P. & Spence C. (1995). S-cone light adaptation: effects of moderately intense adapting flashes. In Colour Vision Deficiencies XII (Editor B. Drum). Documenta Ophthalmologica Proceedings Series, Vol.57, 38, p. 321-326. Kluwer Academic publishers, Dordrecht, The Netherlands. Frumkes T.E., Lange G., Naarendorp F. & Eysteinsson T. (1995) Suppressive rod-cone interactions: underlying mechanisms and practical application. In Colour Vision Deficiencies XII (Edited by B. Drum). Documenta Ophthalmologica Proceedings Series, 57, 39, p. 329-334. Kluwer Academic Publishers, Dordrecht, The Netherlands. Sieving P.A., Murayama K. & Naarendorp F. (1994) Push-pull model of the primate photopic electroretinogram: a role for hyperpolarizing neurons in shaping the bwave. Visual Neuroscience, 11, 519-532. Naarendorp F., Hitchcock P.F. & Sieving P.A. (1993) Dopaminergic modulation of rod pathway signals does not affect the scotopic ERG of cat at dark-adapted threshold. Journal of Neurophysiology, 70, 1681-1691. Naarendorp F. & Frumkes T. E. (1991) The influence of short term adaptation of rods and cones on cone-mediated grating visibility. Journal of Physiology (London), 432, 521-541. Naarendorp F. & Sieving P. A. (1991) The scotopic threshold response of the cat ERG is suppressed selectively by GABA and glycine. Vision Research, 31, 1-15. Naarendorp F., Denny N. & Frumkes T. E. (1988) The influence of rod light and dark adaptation upon cone-mediated spatial acuity. Vision Research, 28, 67-74. Frumkes T. E., Naarendorp F. & Goldberg S. H (1986). The influence of cone adaptation upon rod mediated flicker. Vision Research, 26, 1167-1176. Van Slyck C, Hedstrom L, Lem J & Naarendorp, F. Diurnal effects on pupil size of unrestrained WT mice and mice lacking rod - or cone Function (In preparation).

Abstracts Banden SM, Esdaille TM, Pugh Jr E.N., Naarendorp F. (2007) Some observations on the rodcone character of the behavioral increment threshold function of WT and GNAT1 / mice. Submitted to Annual Meeting of the Association of Research in Vision and Ophthalmology, Ft. Lauderdale, FL Esdaille TM, Banden SM, Naarendorp F. (2006) Absolute and relative sensitivity of the scotopic system of the mouse: behavioral measurements. Annual Meeting of the Society for Neuroscience, New Orleans, LA. Naarendorp F., Esdaille TM., Andrews-Labenski J. & Pugh Jr EN. A new behavioral method for measuring the visual sensitivity of the mouse.(2006). Annual Meeting of the Association of Research in Vision and Ophthalmology, Ft. Lauderdale, FL Akula J.D, Rice M.E.& Naarendorp F. (2005). Dopamine released during subjective twilight suppresses the saturated rod b-wave of the rat electroretinogram. Annual Meeting of the Association of Research in Vision and Ophthalmology, Ft. Lauderdale, FL. Esdaille T.M., Seng R., Caffe A.R., Naarendorp F. (2004) Histological and functional characteristics of the sugar glider retina: a comparison with the mouse retina. Annual Meeting of the Association for Research in Vision and Ophthalmology, Ft. Lauderdale, FL. Akula J.D., Powers R.A., Naarendorp F. (2003) The sensitivity of the rod photoreceptors of the rat derived from the electroretinogram. Annual Meeting of the Society for Neuroscience, New Orleans, LA. Akula J., Orlando N. & Naarendorp F. (2001) Midwave-sensitive cones drive the cone b-wave of the rat electroretinogram. Annual Meeting Society for Neuroscience, San Diego. Naarendorp F., Pugh, E.N., Lyubarsky A.L. Scotopic b-wave as a monitor of small components of rod circulating current suppression. Investigative Ophthalmology and Visual Science Supplement, 41, p. 361. A.L.Lyubarsky, F. Naarendorp, C.-K. Chen, T. Wensel, M.I.Simon, E.N.Pugh, Jr. RGS9-/- mice have profoundly slowed recovery of cone-driven b-wave and a-wave responses after intense flashes. FASEB, Copper Mountain, Colorado. Reeves A & Naarendorp F. (1999) Flicker ERG in early dark adaptation. Investigative Ophthalmology and Visual Science Supplement, 40, p. 236. Naarendorp F., Lirio V. & Cajdric A. (1999) Increment sensitivity of rat: behavioral and eletroretinographic measurements. Investigative Ophthalmology and Visual Science Supplement, 40, p. 1238. Naarendorp F. & Williams G.E. (1997) The electroretinographic response of rat at light offset. Society for Neuroscience Abstracts, 23, p. 1022. Naarendorp F. & Williams G. E. (1997) Positive components in the off-response of the rat ERG. Investigative Ophthalmolology and Visual Science, Supplement 38, p. S884. Naarendorp F. (1996) Duality in the rod response of rat determined by flicker ERG. Investigative Ophthalmolology and Visual Science, Supplement 37, p. S348. Naarendorp F. & Miller P. N. (1995) L-cone influence on rod sensitivity can be modulated by S- cone activity. Investigative Ophthalmolology and Visual Science, Supplement 36, p. S661. Naarendorp F. (1995) Duplicity within the rod mechanism of rat. Society for Neuroscience Abstracts, 21, p. 1645.

Hubbard N.P. & Naarendorp F. (1994) The scotopic threshold response of the rat corneal ERG. Annual Meeting of the Eastern Psychological Association, Providence, RI. Naarendorp F., Paul M. Kortick & Craig Spence. (1993) Light adaptation of the S-cone pathway to moderately intense fields. XIIth Symposium of the International Research Group for Color Vision Deficiencies, Tubingen, Germany. Hubbard N.P. & Naarendorp F. (1994) Effects of dim background lights on the scotopic threshold response of the rat ERG. Investigative Ophthalmolology and Visual Science, Supplement 35, p.2047. Sieving P. A., Richards J. E., Bingham E. L. & Naarendorp F. (1992) Dominant congenital complete nyctalopia & Gly90Asp rhodopsin mutation. Investigative Ophthalmolology and Visual Science, Supplement 33, p.1397. Naarendorp F., Rice K. S. & Sieving P. A. (1991) Effects of rod and blue cone excitation can summate physiologically. Investigative Ophthalmolology and Visual Science, Supplement 32, p. 1092. Sieving P. A., Murayama K. & Naarendorp F. (1991) Monkey cone ERG b-wave results from interaction of depolarizing and hyperpolarizing pathways. Investigative Ophthalmolology and Visual Science, Supplement 32, p. 927. Naarendorp F. & Sieving P. A. (1990) The effects of strychnine and bicuculline on the STR of the cat ERG. Investigative Ophthalmology and Visual Science, Supplement, 31, p. 390. Sieving P. A., Murayama K. & Naarendorp F. (1990) Monkey cone ERG: analysis by PDA, KYN, CNQX, APB, ASP and Co. Society for Neuroscience Abstracts, 16, p.408.