Index Note: Page numbers of article titles are in boldface type. A Acute-phase protein profiles age-associated changes in, 334 335 Adrenal disorders in geriatric horses, 309 310 Aerobic capacity age-related changes in, 318 321 Age as factor for cardiac and respiratory diseases in horses, 283 284 as factor in aerobic capacity and cardiovascular function, 318 322 as factor in body composition and muscle fiber type, 322 323 Aged horse(s). See Geriatric horse(s) Aging anatomic changes associated with, 216 body composition effects of, 322 323, 344 345 immunology of special considerations, 337 impact on feeding and digestive function, 344 347 Alopecia areata in geriatric horses, 268 Anaplastic malignant melanoma in geriatric horses, 274 276 Anthelmintic(s) for geriatric horse, 199 Aortic valvular regurgitation in geriatric horses, 287 291 Aortocardiac fistula in geriatric horses, 293 B Body composition aging effects on, 322 323, 344 345 Bronchiectasis in geriatric horses, 285 C Canine teeth disorders of Vet Clin Equine 32 (2016) 369 378 http://dx.doi.org/10.1016/s0749-0739(16)30020-7 0749-0739/16/$ see front matter vetequine.theclinics.com
370 Index Canine (continued) in geriatric horses, 220 Cardiac disease(s) in geriatric horses, 283 300 aortic valvular regurgitation, 287 291 aortocardiac fistula, 293 bronchiectasis, 285 hypoxia and right heart dysfunction, 286 management of, 295 297 mitral regurgitation, 291 293 pneumonia, 286 287 RAO, 284 285 thoracic neoplasia, 294 295 Cardiovascular disease in geriatric horses, 207 208 Cardiovascular function age-related changes in, 318 321 Cardiovascular hormones aging-related alterations in, 324 Cell populations age-associated changes in, 334 Cheek teeth disorders of in geriatric horses, 221 Chronic inflammatory disease(s) immunosenescence and, 337 Chronic joint disease in geriatric horses, 230 240 (See also Osteoarthritis, in geriatric horses) Colic in geriatric horses, 206 207 Congenital/hereditary diseases primary in geriatric horses, 267 268 Congestive heart failure in geriatric horses management of, 295 297 Corneal disease in geriatric horses, 250 251 Coronary band dystrophy in geriatric horses, 272 273 Cortisol aging-related alterations in, 325 Cushing disease. See Pituitary pars intermedia dysfunction (PPID) Cytokine profiles age-associated changes in, 334 335 D Dental disease in geriatric horses, 206, 215 227 autonomic changes, 216
Index 371 canine teeth disorders, 220 cheek teeth disorders, 221 examination of, 217 218 extraoral pathology, 221 223 incisor teeth disorders, 218 220 introduction, 215 management of, 223 225 prevention of, 199 types of, 218 223 Diabetes mellitus (DM) in geriatric horses, 307 308 Digestive function age-related changes impact on, 344 347 DM. See Diabetes mellitus (DM) E EMS. See Equine metabolic syndrome (EMS) Endocrine disease(s) in geriatric horses, 301 315 (See also specific diseases) adrenal disorders, 309 310 DM, 307 308 EMS, 304 307 glucose homeostasis related, 307 308 introduction, 301 neoplasia-associated hypoglycemia related, 308 PPID, 208, 273 274, 301 304, 346 347, 351 skin disorders, 273 274 thyroid disorders, 308 309 Endorphin aging-related alterations in, 325 Equine metabolic syndrome (EMS) in geriatric horses, 304 307 defined, 304 diagnosis of, 305 307 laminitis with, 304 305 management of, 307 pathophysiology of, 304 305 Euthanasia of geriatric horses, 360 362 experiences of, 361 mortality causes and, 360 361 Exercise aging-induced changes in respiratory function affecting, 322 endocrine response to aging-related alterations in, 323 326 of geriatric horses, 198, 317 332 immune response to, 326 327 introduction, 317 318 systemic effects of, 327
372 Index F Fading Appaloosa syndrome in geriatric horses, 267 Farrier care for geriatric horse, 199 Feeding age-related changes impact on, 344 347 Fistula(s) aortocardiac in geriatric horses, 293 Food intake age-related changes impact on, 345 G Gastrointestinal microbiome nutrient digestibility and, 346 Geriatric horse(s) aging signs in, 200 cardiac and respiratory diseases in, 283 300 (See also Respiratory disease(s); specific diseases and Cardiac disease(s)) comorbidity in, 297 defined, 196, 347 demographics of, 196 197 described, 350 351 diseases of, 200 209 (See also specific types and diseases, e.g.,ophthalmologic disorders, in geriatric horses) cardiovascular disease, 207 208 colic, 206 207 dental disease, 206, 215 227 (See also Dental disease, in geriatric horses) endocrine diseases, 301 315 integumentary disorders, 263 281 laminitis, 206 musculoskeletal disorders, 200, 206, 229 247 neoplasia, 208 209 ocular disorders, 208 ophthalmologic disorders, 249 261 PPID, 208 respiratory disease, 207 euthanasia of, 360 362 exercise and rehabilitation of, 317 332 (See also Exercise; Rehabilitation) immune dysfunction in, 333 341 (See also Immune dysfunction, in geriatric horses) immune function in, 334 336 importance of, 195 196 introduction, 355 356 management of, 197 198 exercise in, 198 feeding in, 197 198 nutritional, 197 198, 343 354 stable management in, 197
Index 373 monitoring of, 347 348 mortality of causes of euthanasia and, 360 361 experiences of, 361 preventive health care for, 198 199 quality of life of, 357 360 role of, 356 357 welfare of, 355 357 Glaucoma in geriatric horses, 252 254 Glucose homeostasis control of metabolic hormones and, 325 326 Growth hormone aging-related alterations in, 324 325 H Hormone(s) aging-related alterations in, 324 326 Human horse bond, 356 357 Hyperparathyroidism in geriatric horses, 309 Hypersensitivity insect bite in geriatric horses, 269 270 Hyperthyroidism in geriatric horses, 309 Hypoglycemia neoplasia-associated in geriatric horses, 308 309 Hypothyroidism in geriatric horses, 308 309 Hypoxia right heart dysfunction and in geriatric horses, 286 I Immune dysfunction in geriatric horses, 333 341 immunosenescence, 333 334 Immune function age-associated changes in, 334 336 cell populations, 334 cytokine and acute-phase protein profiles, 334 335 immune responsiveness, 335 lymphocyte function, 335 neutrophil function, 335 336 Immune responsiveness
374 Index Immune (continued) in geriatric horses age-associated changes in, 335 to exercise, 326 327 Immunologic disorders primary in geriatric horses, 268 273 Immunology of aging special considerations, 337 Immunosenescence, 333 334 clinical consequences of, 336 337 chronic inflammatory diseases, 337 infectious disease risks, 336 vaccine responsiveness, 336 337 Incisor teeth disorders of in geriatric horses, 218 220 Infectious disease(s) immunosenescence and, 336 Insect bite hypersensitivity in geriatric horses, 269 270 Integumentary disorders in geriatric horses, 263 281 introduction, 263 267 primary congenital/hereditary diseases, 267 268 primary endocrine disorders, 273 274 primary immunologic disorders, 268 273 primary neoplastic disorders, 274 279 J Joint disease chronic in geriatric horses, 230 240 (See also Osteoarthritis, in geriatric horses) L Lameness in geriatric horses, 200, 206 Laminitis chronic in geriatric horses, 240 243 in EMS, 304 305 in geriatric horses, 206 Lens disorders in geriatric horses, 254 255 Lymphocyte(s) function of age-associated changes in, 335
Index 375 M Malignant melanoma anaplastic in geriatric horses, 274 276 Mane and tail dystrophy in geriatric horses, 267 268 Melanoma in geriatric horses, 274 malignant anaplastic in geriatric horses, 274 276 Metabolic hormones aging-related alterations in, 325 326 Microbiome gastrointestinal nutrient digestibility and, 346 Mitral regurgitation in geriatric horses, 291 293 Muscle fiber aging effects on, 322 323 Musculoskeletal disease(s) in geriatric horses, 200, 206, 229 247 (See also specific diseases, e.g., Osteoarthritis, in geriatric horses) introduction, 229 230 osteoarthritis, 230 240 N Neoplasia-associated hypoglycemia in geriatric horses, 308 309 Neoplastic disorders in geriatric horses, 208 209 ocular disorders, 256 25 skin disorders, 274 279 thoracic disorders, 294 295 Neutrophil(s) function of age-associated changes in, 335 336 Nutraceuticals for osteoarthritis in geriatric horses, 238 239 Nutrient(s) digestibility of gastrointestinal microbiome and, 346 Nutritional management of geriatric horses, 197 198, 343 354 described, 350 351 feeding- and digestive function related, 344 347 introduction, 343 344 normal horse losing condition, 348 normal obese horse, 348 350 with PPID, 346 347, 351
376 Index O Ocular disorders in geriatric horses, 208 Ophthalmologic disorders in geriatric horses, 249 261 corneal disease, 250 251 glaucoma, 252 254 introduction, 249 250 lens disorders, 254 255 neoplasia, 256 257 retinal disorders, 255 256 uveitis, 252 vision disturbances, 258 vitreous disorders, 255 Osteoarthritis in geriatric horses, 230 240 chronic laminitis, 240 243 clinical signs of, 231 defined, 230 management of, 233 240 local treatment, 234 235 nutraceuticals, 238 239 pain medications, 237 238 supportive treatments, 239 240 surgical, 239 systemic treatment, 235 237 pain in, 231 233 management of, 237 238 pathogenesis of, 230 231 P Pain osteoarthritis-related in geriatric horses, 231 233 medications for, 237 238 Pemphigus complex in geriatric horses, 270 271 Pituitary pars intermedia dysfunction (PPID) in geriatric horses, 208, 273 274, 301 304, 346 347, 351 defined, 301 diagnosis of, 302 303 management of, 303 304 pathophysiology of, 301 302 Pneumonia in geriatric horses, 286 287 PPID. See Pituitary pars intermedia dysfunction (PPID) Primary congenital/hereditary diseases in geriatric horses, 267 268 Primary endocrine disorders of skin
Index 377 in geriatric horses, 273 274 Primary immunologic disorders in geriatric horses, 268 273 Primary neoplastic disorders in geriatric horses, 274 279 Q Quality of life of geriatric horses, 357 360 assessment of, 358 359 owner s role in, 359 360 described, 357 358 factors affecting, 360 R RAO. See Recurrent airway obstruction (RAO) Recurrent airway obstruction (RAO) in geriatric horses, 284 285 Regurgitation aortic valvular in geriatric horses, 287 291 mitral in geriatric horses, 291 293 Rehabilitation of geriatric horses, 317 332 introduction, 317 318 Renal hormones aging-related alterations in, 324 Respiratory disease(s) in geriatric horses, 207, 283 300 aortic valvular regurgitation, 287 291 aortocardiac fistula, 293 bronchiectasis, 285 hypoxia and right heart dysfunction, 286 management of, 295 297 mitral regurgitation, 291 293 pneumonia, 286 287 RAO, 284 285 thoracic neoplasia, 294 295 Respiratory function aging-induced changes in, 322 Retinal disorders in geriatric horses, 255 256 Right heart dysfunction hypoxia and in geriatric horses, 286
378 Index S Sarcoidosis in geriatric horses, 271 272 Skin primary endocrine disorders of in geriatric horses, 273 274 Squamous cell carcinoma in geriatric horses, 276 279 Stable in geriatric horse management, 197 Stress hormones aging-related alterations in, 325 T Teeth of geriatric horses, 206, 215 227 (See also specific teeth and Dental disease, in geriatric horses) Thoracic neoplasia in geriatric horses, 294 295 Thyroid disorders in geriatric horses, 308 309 U Uveitis in geriatric horses, 252 V Vaccination for geriatric horse, 198 199 Vaccine responsiveness immunosenescence effects on, 336 337 Vision disturbances in geriatric horses, 258 Vitreous disorders in geriatric horses, 255 W Welfare of geriatric horses, 355 357 owner responsibilities and awareness, 357