Investing in the pre-school years thinking ahead. Phil Wilson Senior lecturer in infant mental health University of Glasgow

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Investing in the pre-school years thinking ahead Phil Wilson Senior lecturer in infant mental health University of Glasgow

Overview Arguments for public investment in the preschool years Are there critical or sensitive periods in social/emotional/cognitive development? Should we actively seek out problems? Changes in universal NHS child health services and their impact Can we identify problems early? Evaluating universal services

Optimising return on investment Ref: Heckman & Masterov 2007. Similar curves for more advantaged children who receive larger parental investment in the early years.

Critical and sensitive periods The visual system and amblyopia Sensitive periods Is there a critical or sensitive period for social and cognitive development?

Early adversity and programming of stress responses Hunter, Minnis, Wilson. Altered stress responses in children exposed to early adversity: A systematic review of salivary cortisol studies. Stress 2011: early online publicationp

High Sensitive Periods in Early Brain Development Pre-school years School years Numbers Peer social skills Symbol Language Habitual ways of responding Emotional control Vision Hearing Low 0 1 2 3 4 5 6 7 Years Graph developed by Council for Early Child Development, 2000

Conduct disorder should we be seeking it out early? Extreme antisocial/aggressive behaviour Genetic and environmental determinants Strong association with language delay Probably two types: Lifecourse persistent Adolescence-limited

Is there a case for screening?* Wilson & Jungner s s criteria for screening programmes: The condition should be an important health problem The natural history of the condition should be understood There should be a recognisable latent or early symptomatic stage There should be a test that is easy to perform and interpret, acceptable, accurate, reliable, sensitive and specific There should be an accepted treatment recognised for the disease Treatment should be more effective if started early There should be a policy on who should be treated Diagnosis and treatment should be cost-effective Case-finding should be a continuous process *Wilson, Minnis, Puckering, Gillberg ADC 2009;94:812-816 816

Early intervention is almost certainly better than late intervention but it s s hard to prove it! Evidence that conduct disorder is easier to treat early Some support from Glasgow Mellow Babies / Mellow Parenting findings Family-Nurse Partnership trials... Much more work needed particularly trials comparing interventions

Early intervention David Olds 3 randomised controlled trials (RCTs) in US with long-term follow-up 1998 15-year follow up of 400 high-risk children in New York Intervention was 9 antenatal and 23 postnatal nurse visits before age 2 Vs control addressing: General health promotion Maternal personal development Competent care of their children

Early intervention Compared with controls, adolescents born to women who received nurse visits displayed fewer: instances of running away (0.24 Vs 0.60; P=.003), arrests (0.20 Vs 0.45; P =.03), convictions and violations of probation (0.09 Vs 0.47; P<.001), lifetime sex partners (0.92 Vs 2.48; P=.003), cigarettes smoked per day (1.50 Vs 2.50; P=.10), days having consumed alcohol in the last 6 months (1.09 Vs 2.49; P =.03). reported behavioural problems related to use of alcohol and other drugs (0.15 Vs 0.34; P=.08).

Early identification of problems in the population Growing Up in Scotland cohort ALSPAC studies Glasgow pilot work with health visitors SDQ studies

Early identification - GUS Looking for predictors of persisting conduct problems at 3, 4 and 5 years Used Strengths & Difficulties Questionnaire 2070 children born in 2003 with SDQ data at all time points Comparing: 90 children with conduct problems at all 3 times And 1557 who never had conduct problems

Early identification - GUS No. of natural parents in household Two One or none Child s general health Very good or good Fair, bad or very bad Child had some difficulty being understood No Yes Maternal smoking during pregnancy No Yes Agree that smacking is sometimes the only thing that will work No Yes Frequency child taken to visit other people with children Adjusted odds, C.I. and P value 2.10 (1.28, 3.44) <0.01 3.32 (1.35, 8.19) 0.01 1.93 (1.08, 3.44) 0.03 2.35 (1.32, 4.19) <0.01 2.07 (1.13, 3.79) 0.02 Fortnightly or more often Less often or never 2.16 (1.14, 4.09) 0.02 Frequency child is read to Daily Less often 1.86 (0.98, 3.52) 0.06

Early identification - ALSPAC Avon Longitudinal Study of Parents and Children Videos of children parents at age one, in 1992/3 Psychiatric assessment at age 7.5 years (DAWBA) 60 children with psychiatric diagnoses compared with 120 children with no psychiatric diagnosis

ALSPAC preliminary results Positive parenting behaviours are significantly less frequent among parents of children who went on to get oppositional and conduct diagnoses Negative parenting behaviours may be associated with CD/ODD diagnoses Low levels of maternal activity and vocalisation are associated with attention- deficit/hyperactivity disorder (ADHD)

Universal child health services in Scotland Nursing for Health Review of Nursing in the Community. Scottish implementation of HFAC4 The Glasgow Review of Health Visiting The move towards large skill-mix teams Detachment of health visitors from PHCTs and reduced GP involvement Reintroduction of a 30m universal visit (Family Nurse Partnership pilot)

Health for all Children (Hall4) Hall4, ScotGov, 2005: www.scotland.gov.uk/publications/2005/04/15161325/13288

Early Identification: universal HV contacts Pilot data - West Glasgow July-Dec 2009 13 month assessment evaluating parent- child interaction and emotional wellbeing of parent 30 month assessment of parenting stress, child behaviour and language development

Evaluation principles: Glasgow pilot General principles: Use of standardised tools Data useful for 4 purposes: Clinical decision making Needs assessment Performance management External evaluation

The 13 month contact

There are no quick and ready measures of attachment, and those claiming to measure such a construct are most likely measuring something else *. *Lim K, Corlett L, Thompson L, Law J, Wilson P, Gillberg C, Minnis H. Measuring attachment in large population studies: A systematic review. Educational and Child Psychology, in press.

13 month contact Adult wellbeing scale: Anxiety Depression Externally-directed irritability Internally-directed irritability Observational assessment of parent-child interaction* may be problems / probably no problems * Wilson, Thompson, McConnachie, Puckering, Holden, Cassidy, Gillberg. Community Practitioner 2010: 83(5): 22-5

Wilson C, Thompson L, Wilson P. Child; Care Health and Development 2011, published online. Does the 13 month assessment improve targeting of resource?

The 30 month contact

30 month assessment Parenting Daily Hassles poor completion rate Relatively few high scorers Richman Behaviour Checklist Reasonable completion rate Some irrelevant questions Threshold too low High scores strongly associated with language delay

30-month visit - language n % Can your child put 2 words together? 10 3 Does your child know 50 words? 33 10 Half the children with language delay are in the lowest risk category (Core HPI) No clear social patterning

Factors associated with language delay Several factors, as expected, but use of services was the only factor remaining in multivariate analysis. But this only accounted for 22% of cases Bilingualism may also be important Conclusion language delay can only be identified if we ask about it, it can t t be predicted!

Does the 30 month assessment improve targeting of resource?

The Strengths and Difficulties Questionnaire www.sdqinfo.org A brief behavioural screening questionnaire for 2-162 year olds. 3 versions parent, teacher, self-complete Originally developed as a screening tool for psychiatric problems in children but can be used to assess change after interventions and can be used to compare the wellbeing of populations

The SDQ 25 questions used to measure five aspects of the child s development: emotional symptoms conduct problems hyperactivity/inattention peer relationship problems pro-social behaviour Along with questions about impact of problems, if relevant Takes about five minutes to complete

SDQ data collection At a new routine 30 month health check by a community nurse SDQ (parent version) and language assessment Before school entry (completion by nursery staff) In 3 rd year primary school at age 7 (teacher complete) and in 6 th year primary school at age 10 years (self complete)

The new 30-month visit Initial pilot work using language screen and SDQ just completed for 540 children in NHS GGC Likely to be offered by HVs to children in NHS GGC in near future New research allowing detailed assessment of children who appear to have problems at the visit (+/- some who don t) is about to start

The new pilot Glasgow 30 month assessment breaking news...

Primary school entry SDQ Data available for about 75% of Glasgow school entrants about 3,600 in total Good questionnaire completion rates in most nurseries Ongoing qualitative study of impact of data collection on nursery and primary staff Study comparing parent and staff completed SDQs: in progress

Conduct problems at primary school entry Corrected for deprivation, nursery, looked after status, sex

Conclusions Stratifying risk in early infancy is inadequate We need to continue some universal child health contacts We should acknowledge that HVs (and GPs) are best placed to identify vulnerability early Health visitors (and GPs) probably need additional training We need to develop new care pathways We need better population-level level data Specifically to assess whether interventions work Involve GPs and their IT systems?

Evaluating universal services future plans Disentangling the impact of neighbourhood, availability/use of services Linkage of health and education data: plotting trajectories from 2 to 10 years Identify effects of area, nursery, school, and use of services on these trajectories Trials of interventions aiming to improve population wellbeing and reduce inequalities

Acknowledgements Carolyn Wilson and the SG Child and Maternal Health Division John Butcher, Amanda Kerr, Michele McClung, Morag Gunion and City of Glasgow Education Services Christine Puckering, Helen Minnis,, Chris Gillberg Lucy Thompson, Kim Jones & Kelly Chung Paul Bradshaw Paula Barton & Sarah Barry Fiona McQuaige Scottish Government produced the socio-economic data and Scottish Neighbourhood Statistics provided the datazone information.

Thank you! philip.wilson@glasgow.ac.uk