A Cancer Fighting Diet. Lindsay Brechbill RD, CD, CSO Clinical Oncology Dietitian UW Cancer Center at ProHealth Care

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A Cancer Fighting Diet Lindsay Brechbill RD, CD, CSO Clinical Oncology Dietitian UW Cancer Center at ProHealth Care

Objectives To promote knowledge of preventative measures individuals can take to reduce cancer risk Understand how nutrition may prevent promotion of cancer Review the AIRC and World Cancer Fund s recommendations for cancer prevention Identify common foods that have been researched for cancer fighting properties

Control the Controllables Cancer Prevention

Radiation, Chemicals, Viruses, Carcinogens Initiated Cell DNA Repair Cell Cycle Arrest & Apoptosis Folate, Selenium Selenium, Curcumin Normal Cell Genetic Damage Genetic Damage Precancerous Antioxidants How may nutrition help? *Supplement doses of some nutrients may promote damage or tumor growth Malignant Tumor Figure reproduced from: Oncology Nutrition for Clinical Practice, DPG; Leser et al.

Phytochemicals Provide plants with color, odor, and flavor Researched benefits: Stimulate the immune system Block substances we eat, drink, and breathe from becoming carcinogens Reduce inflammation Prevent DNA damage and help with DNA repair Reduce oxidative damage Slow the growth rate of cancer cells Triggers cell apoptosis Helps regulate hormones American Institute for Cancer Research. (April 10, 2013). Phytochemicals: The Cancer Fighters in the Foods We Eat. AICR: Diet, What We Eat. Retrieved from: http://www.aicr.org/reduce-your-cancer-risk/diet/elements_phytochemicals.html

Recommendations for Cancer Prevention World Cancer Research Fund & AICR We help people make choices that reduce their chances of developing cancer. Last Updated Report: 2007 10 recommendations for Cancer Prevention drawn from the WCRF/AICR Second Expert Report American Institute for Cancer Research. (September 09, 2014). Recommendations for Cancer Prevention. Retrieved from: www.aicr.org/reduce-your-cancer-risk/recommendations-for-cancer-prevention/

Body Weight Be as lean as possible without being underweight.

Physical Activity Be physically active as part of everyday life.

Foods and Drinks that Promote Weight Gain Limit consumption of energy-dense foods. Avoid sugary drinks.

Plant Foods Eat mostly foods of plant origin.

Animal Foods Limit intake of red meat and avoid processed meat.

Alcoholic Drinks Limit alcoholic drinks: 1 per day for women, 2 per day for men.

Preservation, Processing, and Preparation Limit consumption of salt.

Dietary Supplements Aim to meet nutritional needs through diet alone.

Breastfeeding Mothers to breastfeed; children to be breastfed.

Cancer Survivors Follow the recommendations for cancer prevention.

Foods You Should Know About Recommendations from AICR American Institute for Cancer Research. (March 25, 2015). AICR s Foods that Fight Cancer. Retrieved from: www.aicr.org/foods - that-fight-cancer/

Apples Good source of fiber & vitamin C Diets high in fiber convincingly decrease risk for: colorectal cancer Research is pointing to the fact there is not one single phytochemical that supplies apples anti-cancer properties... It s the whole apple. - Rui Hai Liu, Cornell University.

Blueberries & Other Berries May help reduce age-related memory loss Excellent source of vitamins C & K, manganese, and a good source of fiber Among the highest in antioxidants due to many phytochemicals Aim for 1 serving daily

Broccoli & Cruciferous Vegetables Four-petal flowers which resemble a cross Includes: broccoli, Brussels sprouts, rapini, cabbage (green), cauliflower, turnips (white), dark green leafy vegetables Glucosinolates are found in all cruciferous vegetables May induce detoxification of carcinogens, limit production of cancer related hormones, block carcinogens and prevent tumor growth American Institute for Cancer Research. (April 10, 2013). Phytochemicals: The Cancer Fighters in the Foods We Eat. AICR: Diet, What We Eat. Retrieved from: http://www.aicr.org/reduce-your-cancer-risk/diet/elements_phytochemicals.html

Coffee & Tea Good source of riboflavin (B-Vitamin) Concentrated source of antioxidant phytochemicals Probably lowers risk for endometrial and liver cancers Skip cream and sugar! Tea: Limited but suggested evidence; phytochemicals

Dried Beans, Lentils, and Peas (Legumes) Aim for intake of at least ½-1 cup every day. Kidney and black beans, yellow split peas, lentils, etc. Excellent source of dietary fiber Contain resistant starch Used by healthy bacteria to produce short-chain fatty acids which seem to protect colon cells Good source of protein, folate Folate may be protective against pancreatic cancer as it is essential for healthy DNA and maintaining control of cell growth American Institute for Cancer Research. (May 17, 2013). AICR s Foods that Fight Cancer: Dry Beans and Peas (Legumes). Retrieved from: www.aicr.org/foods-that-fight-cancer/legumes.html#research

Flaxseed Excellent source of magnesium, manganese, thiamin, fiber Omega-3 s & Lignans Ground is preferable Add to cereals, yogurt, smoothies, salads, baked goods Aim for 1 TBSP per day

Garlic Allium family: onions, scallions, leeks, and chives Probably protective against stomach cancer Many substances that may protect against cancer Animal Studies Slowed development of cancer for stomach, breast, esophagus, colon, and lung Activate substances by chopping and letting sit for 10-15 minutes

Walnuts All nuts are cancer-preventive Omega-3 Phytosterols: help lower blood cholesterol "Several animal studies show that including walnuts in the diet slows or prevents the growth of breast and prostate cancers. The addition of walnuts to your plate is a good cancer preventive measure. - Lauri Byerley, PhD, LSU Health New Orleans

Take Away No single food or food component can protect you again cancer by itself. But strong evidence does show that a diet filled with a variety of plant foods such as vegetables, fruits, whole grain and beans helps lower risk for many cancers. Eat food. Not too much. Mostly plants. Michael Pollan

Questions? Thank you!