Product Datasheet. DC-LAMP Antibody (104G4) DDX0190P-100. Unit Size: 0.1 mg. Store at -20C. Avoid freeze-thaw cycles.

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Product Datasheet DC-LAMP Antibody (104G4) DDX0190P-100 Unit Size: 0.1 mg Store at -20C. Avoid freeze-thaw cycles. Publications: 18 Protocols, Publications, Related Products, Reviews, Research Tools and Images at: www.novusbio.com/ddx0190p-100 Updated 3/13/2018 v.20.1 Earn rewards for product reviews and publications. Submit a publication at www.novusbio.com/publications Submit a review at www.novusbio.com/reviews/destination/ddx0190p-100

DDX0190P-100 DC-LAMP Antibody (104G4) Product Information Unit Size Concentration Storage Clonality Clone Preservative Isotype Purity 0.1 mg 0.5 mg/ml Store at -20C. Avoid freeze-thaw cycles. Monoclonal 104G4 No Preservative IgG1 Ion exchange chromatography Buffer Tris-NaCl (ph 8.0) Page 1 of 4 v.20.1 Updated 3/13/2018 Product Description Host Mouse Gene ID 27074 Gene Symbol Species Immunogen Notes Product Application Details Applications LAMP3 Human, Sheep DC-LAMP/CD208 was used as immunogen. This product is manufactured by Dendritics and distributed by Novus Biologicals in North America and other select countries. To order in the following countries: Germany, Finland, United Kingdom, Norway, Denmark, Switzerland, Austria and South Korea, please contact Dendritics for additional ordering information. Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry- Paraffin Recommended Dilutions Flow Cytometry 1:10-1:1000, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen 1:10-1:500 Images Immunocytochemistry/Immunofluorescence: DC-LAMP Antibody (104G4) [DDX0190P-100] - Sheep submaxillary lymph node cortex cryosection

Immunohistochemistry: DC-LAMP Antibody (104G4) [DDX0190P-100] - IHC on cryosection of human tonsil: double staining CD3 ( red) DC- LAMP 104G4(blue) Page 2 of 4 v.20.1 Updated 3/13/2018 Flow Cytometry: DC-LAMP Antibody (104G4) [DDX0190P-100] - Intracellular FACS staining of human monocytes cultured 24h with GM- CSF, IL4, LPS Immunohistochemistry-Frozen: DC-LAMP Antibody (104G4) [DDX0190P-100] - Analysis of human lung frozen section with clone 104G4 (DX0190) Flow Cytometry: DC-LAMP Antibody (104G4) [DDX0190P-100] - DC- LAMP: dendritic cell maturation marker

Publications de Saint Vis B et al. A novel lysosome-associated membrane glycoprotein, DC-LAMP, induced upon DC maturation, is transiently expressed in MHC class II compartment. Immunity 1998 Sep [PMID: 9768752] Chang C et al. Primary central nervous system diffuse large B-cell lymphoma has poorer immune cell infiltration and prognosis than its peripheral counterpart. Histopathology 2015 Nov [PMID: 25829022] Tseng WW et al. Analysis of the intratumoral adaptive immune response in well differentiated and dedifferentiated retroperitoneal liposarcoma. Sarcoma 2015 [PMID: 25705114] Pavot V et al. Cutting edge: New chimeric NOD2/TLR2 adjuvant drastically increases vaccine immunogenicity. J Immunol 2014 Dec [PMID: 25392526] Gulati et al. Molecular characterization of human skin response to diphencyprone at peak and resolution phases: therapeutic insights. J Invest Dermatol 2014 Oct [PMID: 24751728] Takechi H et al. Clinical and immunological implications of increase in CD208+ dendritic cells in tonsils of patients with immunoglobulin A nephropathy. Nephrol Dial Transplant 2013 Dec [PMID: 24081865] Debeer S et al. Comparative histology and immunohistochemistry of porcine versus human skin. Eur J Dermatol 2013 Jul-Aug [PMID: 24047577] Schwingshackl P et al. Distribution and maturation of skin dendritic cell subsets in two forms of cutaneous T-cell lymphoma: mycosis fungoides and Sezary syndrome. Acta Derm Venereol 2012 May [PMID: 22678564] Irla N et al. Alitretinoin abrogates innate inflammation in palmoplantar pustular psoriasis. Br J Dermatol 2012 Nov [PMID: 22612660] Vermi W et al. Spontaneous regression of highly immunogenic Molluscum contagiosum virus (MCV)-induced skin lesions is associated with plasmacytoid dendritic cells and IFN-DC infiltration. J Invest Dermatol 2011 Feb [PMID: 20739948] Huch JH et al. Impact of varicella-zoster virus on dendritic cell subsets in human skin during natural infection. J Virol 2010 Apr [PMID: 20130046] van Dongen M et al. Anti-inflammatory M2 type macrophages characterize metastasized and tyrosine kinase inhibitortreated gastrointestinal stromal tumors. Int J Cancer 2010 Aug [PMID: 20013807] More publications at http://www.novusbio.com/ddx0190p-100 Page 3 of 4 v.20.1 Updated 3/13/2018

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