19 22 2015 05 28 Chinese Journal of Tissue Engineering Research May 28, 2015 Vol.19, No.22 1 2 1 1 ( 1 830002 2 830002) 1 2 3 (XYDCX2014185) / Cobb 1981 2005 830002 :R318 :B :2095-4344 (2015)22-03590-05 2015-03-16 http://www.crter.org. [J].2015 19(22):3590-3594. doi:10.3969/j.issn.2095-4344.2015.22.027 Pedicle screw placement combined with filler for lumbar vertebra fractures Zhou Gang 1, Gan Zi-ming 2, Huang Wei-min 1, Wang Cheng-wei 1 ( 1 Department of Spine Surgery, Sixth Affiliated Hospital, Xinjiang Medical University, Urumqi 830002, Xinjiang Uygur Autonomous Region, China; 2 Basic Medical College, Xinjiang Medical University, Urumqi 830002, Xinjiang Uygur Autonomous Region, China) Abstract BACKGROUND: Conventional cross-segment pedicle screw fixation will cause some complications such as kyphosis and loss of corrective angle. Fixation of pedicle screw placement of the injured vertebral body improves the disadvantages of conventional posterior screw placement, and obtains ideal outcomes. OBJECTIVE: To investigate the clinical application value of pedicle screw placement combined with filler for lumbar vertebra fracture. METHODS: Clinical data of patients with pedicle screw placement combined with filler for lumbar vertebra fracture were retrospectively analyzed. They were repaired with pedicle screw placement combined with bone graft as well as pedicle screw placement combined with bone cement. The ratio of anterior border to posterior border of the injured vertebral body after surgery and changes in Cobb angle were observed. Patients were followed up and results were compared. RESULTS AND CONCLUSION: Pedicle screw placement combined with filler has many advantages, and obtained good outcomes in the treatment of lumbar vertebral fracture. However, the extensive application has some problems and disputes. Clinical physicians should pay more attention on choice of surgical indications, prevention and treatment of perioperative and long-term complications and postoperative treatment of osteoporosis. The pedicle screw fixation combined with calcium phosphate bone cement has a broad prospect, can maintain the effect of spine reduction, and is worth to spread in the clinical treatment of lumbar fractures. Zhou Gang, Studying for master s degree, Attending physician, Department of Spine Surgery, Sixth Affiliated Hospital, Xinjiang Medical University, Urumqi 830002, Xinjiang Uygur Autonomous Region, China Corresponding author: Gan Zi-ming, Professor, Master s supervisor, Basic Medical College, Xinjiang Medical University, Urumqi 830002, Xinjiang Uygur Autonomous Region, China Accepted: 2015-03-16 3590 P.O. Box 10002, Shenyang 110180
. Subject headings: Pedicle Screw; Fractures, Bone; Calcium Phosphates Funding: Research Innovation Fund Project of Xinjiang Medical University, No. XYDCX2014185 Zhou G, Gan ZM, Huang WM, Wang CW. Pedicle screw placement combined with filler for lumbar vertebra fractures. Zhongguo Zuzhi Gongcheng Yanjiu. 2015;19(22):3590-3594. 0 Introduction [1] [2] / β-tcp [3-7] [5] [8-12] 1Data and methods 1.1 2010 1 2015 1 1.2 1.3 72 18 1.4 2012 1 2013 1 2218 4 22 67 35.5 2 d 14 d4 d2 4 164 711Certibein 1 A1 2 A2 10 A3 5 B1 4 B2 2212 Frankel 4 B 2 C 6 D 22 [13] SPSS 13.0 Cobb 2 Results 2.1 22 6 2.2 22 Cobb (P < 0.01) 1 1 Cobb (x _ ±s) Cobb ( ) 0.31±0.13 25.2±7.7 0.84±0.02 11.2±1.4 0.82±0.05 11.7±1.8 3 6 Cobb (P > 0.05) 12 ISSN 2095-4344 CN 21-1581/R CODEN: ZLKHAH 3591
. FrankelB 2 C 3 D 3 E 4 2.3 [14] 2008 1 2012 12 105 78 27 12 3619 [15] 2008 1 2011 12 42 39 28.4 (11.0 34.3 ) 111 38 [16] 2011 10 2013 1172 ( n=34) ( n=38) 12 14 3 Cobb (P > 0.05) 1 Cobb (P < 0.05) 3 1 1 ; (P < 0.05) Cobb 2 3 [17] 2 [14] [15] Cobb (x _ ±s ) [14] 21.8±2.9 6.9±1.3 7.3±1.2 [15] 33.6±8.7 3.1±2.0 3.2±2.5 3 [16] Cobb (x _ ±s ) 1 21.8±3.3 11.2±3.4 13.8±3.7 22.1±2.8 10.9±3.5 10.1±1.9 2.4 4 5 3 Discussion [23] [24] Cobb 3592 P.O. Box 10002, Shenyang 110180
. 4 ( ) [18] 32 23 65 12-24 [19] 35 21 67 12-36 [20] 95 18 61.5 > 12 [21] 20 58 84 12 18 [22] 78 55 89(n= 42 A ) 58 80(n=36 B ) A B 3 7 5 [18] [19] [20] [21] [22] Cobb (P < 0.05) Frankel (P < 0.05) Cobb, (P < 0.05);(P > 0.05) 25,,,, 1 1,,, Cobb VAS A B (P > 0.05) Cobb VAS B A (P < 0.05) (P < 0.05) X CT2 A B Cobb VAS (P < 0.05) 1 A B (P < 0.05) 1 3 A B (P > 0.05) Cobb 50%20 40 50% 60% [25] [26] Cobb ; ISSN 2095-4344 CN 21-1581/R CODEN: ZLKHAH 3593
. [27,28] [29] [30] [31] 4 References [1],,,. [J]..2005,25(5):293-296. [2],,,. [J]. :,2013,7(14):6477-6480. [3],,.β [J].,2007,5(5):298-301. [4],,,. [J].,2014,27(2):128-132. [5],,,. [J].,2013,17(21):3823-3830. [6] Xiaodong Y,Yu W,Hailin L, et al.augmentation of pedicle screw fixation strength using an injectable calcium sulfate cement an in vivo study.spine.2008;33(23):2503-2509 [7] Bostan B,Esenkaya I,Gunes T,et al.a biomechanical comparison of polymethylmethacrylate-reinforced and expansive pedicle screws in pedicle-screw revisions. Acta Orthop Traumatol Turc.2009;43(3):272-276. 3594 [8],. [J]., 2002,22(1):49-51. [9],,.[J]., 2005, 19(2):17-19. [10],,,. [J].,2003,20(5):303-309. [11] Sarda S,Fernández E,Llorens J,et al.rheological properties of an apatitic bone cement during initial setting.j Mater Sci Mater Med.2001;12(10-12):905-909. [12] Leroux L,Hatim Z,Fr che M,et al. Effects of various adjuvants (lactic acid, glycerol, and chitosan) on the injectability of a calcium phosphate cement.bone.1999;25(2):31s-34s. [13],,. [J]..2006,26(4):217-222. [14],,,. [J].,2014,12(5):289-292. [15],. [J].,2014,29(1): 12-14. [16],,,. [J].,2015,21(6): 1000-1003. [17],,,. [J]., 2012,27(9):823-824 [18]. 32[J]..2014, 11(6): 65-67. [19],,,. [J]., 2008,23(4):277-279. [20],,,. [J]..2013,10(3): 19-22. [21],,,,,,,. [J].,2014,18(30):4757-4763. [22],,,. [J].,2015,30(1):21-23. [23],,,. [J]..2009,30:7 [24],,,. [J]..2010,23(4):264-267. [25]. [J].,2004, 17(2):120-121. [26],,,. [J].,2013,(6):531-534. [27] Vedaan JJ,Diekerhof CH,Buskens E,et al.surgical treatment of traumatic fractures of the thoracic and hmbar spine.spine. 2004; 29(7):803-814. [28],,. [J].,2009,37(6):985-987. [29],,,. 52 [J].,2013,8(5):495-497. [30] Vedaan JJ,Diekerhof CH,Buskens E,et al.surgical treatment of traumatic fractures of the thoracic and lumbar spine.spine. 2004;29(7):803-814. [31] Boucher M,Bhandari M.Kwok D,et al.heahh-related quality of life after short segment instrumentation of lumbar burst fractures. J Spinal Disord.2001;14(5):417-426. P.O. Box 10002, Shenyang 110180