Staying on top of the current research landscape with InCites Benchmarking & Analytics: An immuno-oncology case study

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Staying on top of the current research landscape with InCites Benchmarking & Analytics: An immuno-oncology case study SLA Annual Conference Biomedical & Life Sciences Division Breakfast June 2017 Amy Braden, MSLIS

What is Clarivate Analytics? 2

What is immuno-oncology? 3

4 2,517 Number of organizations publishing research on I/O 85 Number of companies publishing research on I/O 466 Number of organizations funding research on I/O

5 2,517 Number of organizations publishing research on I/O 85 Number of companies publishing research on I/O 466 Number of organizations funding research on I/O

InCites & the Web of Science Core Collection 6

InCites & the Web of Science Core Collection 7

138% growth in Immuno-oncology (I/O) annual publications over the last 10 years 8 5000 4500 Web of Science Core Collection Journal Articles 4,424 4000 3500 3000 2500 2000 records 1500 1000 1,780 500 0 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 Source: Web of Science Core Collection

Timeline of I/O 9 Morrissey, K., Yuraszeck, T., Li, C.-C., Zhang, Y. and Kasichayanula, S. (2016), Immunotherapy and Novel Combinations in Oncology: Current Landscape, Challenges, and Opportunities. Clinical And Translational Science, 9: 89 104. doi:10.1111/cts.12391

Who is doing high impact research in I/O? Top 10 publishing organizations by Category Normalized Citation Impact (CNCI) 10 1.0 = average impact in field

Category Normalized Citation Impact 11 Business Law Substance Abuse Biology Oncology Respiratory System Agronomy times cited 1990 2015 Review Article Editorial Category Citation patterns differ by subject category e.g. nanotechnology vs law Time Citations accumulate over time and at different rates depending on article age and category e.g. new articles may accumulate citations quickly, older ones more slowly or not at all Document Type Citations differ by document type within a journal e.g. reviews are generally more heavily cited than articles, and editorials, book reviews etc. may go uncited Normalization puts data into context is an entity doing better or worse than would be expected in a journal or category?

Which government institutions are doing high impact research in I/O? Top 5 U.S. government organizations by CNCI 12

Which academic institutions are doing high impact research in I/O? Top 5 U.S. academic organizations by CNCI 13

Which corporate institutions are doing high impact research in I/O? Top 5 corporate organizations by CNCI 14

15 Who are the Key Opinion Leaders on I/O? Top 10 Global Authors by CNCI Rank Name Affiliation Country Category Normalized Citation Impact 1 Topalian, Suzanne L. Johns Hopkins University USA 31.06 2 Pardoll, Drew M. Johns Hopkins Oncology Center USA 30.98 3 Daud, Adil University of California San Francisco USA 28.18 4 Korman, Alan J. Bristol Myers Squibb USA 27.55 5 Carvajal, Richard D. Memorial Sloan Kettering Cancer Center USA 27.28 6 Chen, Lieping Yale University USA 25.97 7 Taube, Janis M. Johns Hopkins University USA 25.3 8 Brahmer, Julie R. Johns Hopkins Oncology Center USA 23.87 9 Hwu, Wen-Jen UTMD Anderson Cancer Center USA 23.03 10 Antonia, Scott J. H Lee Moffitt Cancer Center & Research Institute USA 22.49 1.0 = average impact in field

16 Who are the Key Opinion Leaders on I/O? Top 10 Authors Outside the U.S. by CNCI Rank Name Affiliation Country Category Normalized Citation Impact 1 Kefford, Richard University of Sydney AUSTRALIA 19.76 2 Perez-Gracia, Jose L. University of Navarra SPAIN 18.42 3 Long, Georgina V. University of Sydney AUSTRALIA 13.43 4 Robert, Caroline Gustave Roussy FRANCE 9.39 5 Graus, Francesc IDIBAPS SPAIN 8.47 6 Riddell, Stanley R. Technical University of Munich GERMANY 8.09 7 Schachter, Jacob Chaim Sheba Medical Center ISRAEL 7.05 8 Rusakiewicz, Sylvie Institut National de la Sante et de la Recherche Medicale FRANCE 5.97 9 Mellman, Ira Roche Holding SWITZERLAND 5.9 10 Lebbe, Celeste Pierre & Marie Curie University - Paris 6 FRANCE 5.79 1.0 = average impact in field

What is the funding* landscape for I/O? Top 10 Global Funders by number of funded documents 17 *Data derived from the funding acknowledgments in the journal articles

What is the funding* landscape for I/O? CNCI of Top 10 Global Funders by number of funded documents BMS-Funded Institutions Web of Science 18 (Top 10 by output) Documents Memorial Sloan Kettering Cancer Center 52 Harvard University 41 Bristol Myers Squibb 40 Johns Hopkins University 35 VA Boston Healthcare System 34 Dana-Farber Cancer Institute 31 Johns Hopkins Oncology Center 30 H Lee Moffitt Cancer Center & Research Institute 23 UTMD Anderson Cancer Center 22 Cornell University 20 1.0 = average impact in field *Data derived from the funding acknowledgments in the journal articles

What collaborations are happening in I/O? Top MSKCC Collaborations by number of co-authored documents MSKCC Collaborating organizations defined as co-authorship Ranked clockwise by # coauthored papers Displaying CNCI 19

What collaborations are happening in I/O? Top Johns Hopkins Oncology Center Collaborations by number of co-authored documents Johns Hopkins Oncology Center Collaborating organizations defined as co-authorship Ranked clockwise by # coauthored papers Displaying CNCI 20

21 What organizations are publishing hot papers on I/O? Organization Number of Hot Papers Harvard University 7 UNICANCER 7 Yale University 6 Gustave Roussy 6 VA Boston Healthcare System 6 University of California Los Angeles 5 Dana-Farber Cancer Institute 5 Memorial Sloan Kettering Cancer Center 5 University of Chicago 4 University of North Carolina Chapel Hill 4 Vanderbilt University 4 UTMD Anderson Cancer Center 4 Merck & Company 4 Hot Papers are papers published in the last two years, and receive the top 0.1% of citations in the past two months.

Who is funding* the Hot Papers in I/O? 22 Organization Number of Hot Papers National Institutes of Health (NIH) - USA 14 NIH National Cancer Institute (NCI) 8 Merck & Company 3 KWF Kankerbestrijding 2 European Research Council (ERC) 2 Hot Papers are papers published in the last two years, and receive the top 0.1% of citations in the past two months. *Data derived from the funding acknowledgments in the journal articles

23 Who is funding the next breakthrough? Which KOLs should I work with? What hot research am I missing?

24 HOT TOPIC SESSION Using Bibliometrics in the Library: Best Practices for Research Evaluation Tuesday, June 20 th 9:00-10:00 AM Room CC-223

Amy Braden, Solutions Specialist amy.braden@clarivate.com clarivate.com

Appendix

Web of Science Core Collection The world s most trusted citation index. Powerful bibliographic and cited reference search capabilities, together with the benefits of cited reference linking and navigation. Cover-to-cover indexing of over 18,000 journals Over 12,000 conferences covered, annually Over 80,000 scholarly books Science Citation Index Expanded Social Sciences Citation Index Arts and Humanities Citation Index Emerging Sources Citation Index Conference Proceedings Citation Index Book Citation Index Multidisciplinary International Influential Master Journal List Conferences List Book List

Web of Science Core Collection Search 28 The following search was used for the immuno-oncology analysis in this presentation: TOPIC = ("immuno oncol*" or (immunotherap* and (cancer or tumo$r* or neoplas* or oncol* or *oma))) Refined by: DOCUMENT TYPES: (ARTICLE OR REVIEW OR PROCEEDINGS PAPER) AND [excluding] DOCUMENT TYPES: (RETRACTED PUBLICATION )