Grandio blocs / Grandio disc STRONGEST IN ITS STRONGEST IN ITS 86% FILLED NANO-CERAMIC HYBRID CAD/CAM MATERIAL

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STRONGEST IN ITS STRONGEST IN ITS CLASS CLASS Grandio blocs / blocs / disc 86% FILLED NANO-CERAMIC HYBRID CAD/CAM MATERIAL

Grandio blocs / OPTIMAL TOOTH-LIKE PHYSICAL PROPERTIES FOR ENHANCED PERFORMANCE Resin-based restoratives have been employed for permanent restorations for many years providing optimal properties for everyday use throughout the world and backed by a multitude of studies. In the realm of CAD/CAM restoratives there is a large diversity of materials available for use ranging from silicate ceramics and lithium disilicate to hybrid ceramics, zirconium dioxide and composite. Material characteristics similar to those of natural tooth structure such as dentin-like modulus of elasticity, low shrinkage, and high filler rates are proven to benefit current resin-based restorations in regards to marginal integrity and longevity. Today VOCO introduces Grandio blocs and, a highly filled (86%) CAD/CAM restorative block and disc that is based on a Nano-ceramic Hybrid technology. This technology offers these tooth-like physical properties, with maximum long-term strength as a restorative with benefits for the patient while also delivering key advantages for the practitioner. Similar to natural tooth structure The modulus of elasticity is a measure of the resistance that a material exerts against its deformation. In the best case scenario, it should be the same as that of natural tooth structure. Grandio blocs and also achieve this with ease, and thus offer not only extremely high strength, but also the similarity to natural tooth structure desired by practitioners. Like most materials, composite restoratives expand when heated and contract when they cool down. This behavior is also true of human dentition, when one consumes warm/hot food followed by a cool drink. If the expansion of the restoration is greater than that of the tooth itself, a tensile force develops at the interface where tooth structure meets restorative i.e. the adhesive layer. The study conducted by Wolter et al. revealed that Grandio blocs comes closer than any other blocks to the values recorded for natural tooth structure (cf. Xu et al., 1989). [1-6 /K] 4 3 3 2 2 1 1 Enamel Dentin Grandio blocs Coefficient of thermal expansion Cerasmart Ambarino Source: H. Wolter et al., Fraunhofer ISC Würzburg, report to VOCO, 216 Antagonist-friendly The two-body wear test shows that Grandio blocs demonstrates similarly low wear to lithium disilicate and is also antagonist-friendly. VITA Enamic [GPa] 3 Modulus of elasticity [µm] 3 Two-body wear 2 2 1 1 3 2 2 1 1 Wear of specimen Wear of antagonist Wear overall Grandio blocs Cerasmart Ambarino Brilliant Crios VITA Enamic Grandio blocs Cerasmart Ambarino VITA Enamic IPS e.max CAD Source: Spintzyk, S.; Geis-Gerstorfer, J. et al, 4th EuroBioMat, Weimar, 217 Source: J. Geis Gerstorfer et al., University of Tübingen, report to VOCO, 216 2 Lava, Cerasmart, Ambarino, Brilliant Crios, Vita Enamic, and IPS e.max CAD are not registered trademarks of VOCO GmbH.

GRANDIO BLOCS / GRANDIO DISC Grandio blocs / HIGHLY FILLED FOR MAXIMIZED STRENGTH Strongest in Class Overall, the study results presented within this brochure demonstrate that VOCO's Nano-ceramic Hybrid CAD/CAM material is stronger than the composite-based CAD/CAM materials currently available on the market. Extraordinary strength In a study conducted by the University of Tübingen into biaxial flexural strength, a value of 333 MPa was recorded for Grandio blocs. This result was far superior to the composite-based blocks. With this extraordinary strength and the highest filler content, at 86 % by weight, Grandio blocs maximizes it s durability as a restoration. [% w/w] Filler content [MPa] Biaxial flexural strength 1 9 8 7 6 4 3 2 1 86 Grandio blocs/ 8 71 7.1 Cerasmart Ambarino 4 4 3 3 2 2 1 1 Grandio blocs Cerasmart Ambarino VITA IPS e.max Enamic CAD Source: Manufacturer s specifications Source: J. Geis Gerstorfer et al., University of Tübingen, report to VOCO, 216 At 86 % by weight, our CAD/CAM material boasts the highest filler content compared to the composite-based blocks/discs. This is achieved through VOCO s proprietary nano-technology and guarantees outstanding strength and stability. [% w/w] 3 Lowest content of Resin 29 29.9 Overall, Grandio blocs and based on the Nanoceramic Hybrid technology, offer an optimized combination of strength and tooth-like physical properties that make the Grandio blocs and easier for the practitioner to work with, saving time and money while offering the patient a long-lasting restoration with durability and uncompromised esthetics. 2 2 1 1 14 Grandio blocs/ 2 Cerasmart Ambarino Source: in accordance with manufacturer information Lava, Cerasmart, Ambarino, Vita Enamic, and IPS e.max CAD are not registered trademarks of VOCO GmbH. 3

Grandio blocs / ENGINEERED PHYSICAL PROPERTIES FOR BETTER LONGEVITY AND ESTHETICS Water absorption Comparatively, Grandio blocs and have extremely low water absorption which provides a higher quality of overall performance for better longevity, especially when combined with their enhanced tooth-like physical properties. [µg/mm 3 ] 4 3 3 2 2 1 1 Water absorption Grandio blocs/ Cerasmart VITA Enamic Brilliant Crios Ambarino Source: acc. ISO 449, VOCO, 217 High radiopacity for easy identification Grandio blocs and offer very high radiopacity (38 % Al) compared to other brands available on the market. This adds to Grandio blocs and ease-of-use in regards to identification during the reviewal of radiographs. [%Al] 3 3 2 2 1 1 Radiopacity Grandio blocs/ Cerasmart VITA Enamic Brilliant Crios Shofu Block HC Source: acc. ISO 449, VOCO, 217 Before After Initial situation teeth 36 and 37 Source: Dr. Jongki Hadi, Indonesia Cemented Restorations Final Restorations with characterization of the fissures. 4 Lava, Cerasmart, Ambarino, Brilliant Crios, Vita Enamic, and Shofu Block HC are not registered trademarks of VOCO GmbH.

GRANDIO BLOCS ADMIRA / GRANDIO FUSION DISC Grandio blocs / NANO-CERAMIC HYBRID ADVANTAGES THAT MATTER In addition to its outstanding physical values, Grandio blocs/ Edges after grinding also offer a whole range of additional advantages, which makes these materials an ideal alternative to ceramics: VITA Enamic IPS e.max CAD Grandio blocs Thinner crown margins The use of VOCO s Nano-ceramic Hybrid materials make it possible to mill even thin tapered edges with precision and without the risk of chipping or breakages. This means precision-fit restorations that are also easy to polish both inside and outside the mouth. No firing saves time Compared to the use of lithium disilicate, VOCO s Nanoceramic Hybrid materials eliminates the need for the Source: Internal pictures, veneer.6 mm firing process. As a completely polymerized Nano- ceramic Hybrid restoration, they can be immediately placed following the milling procedure saving time and money. This enables you to truly offer your patients a complete restoration in just one simple visit. Simple characterization with standard composite Grandio blocs and come in monolithic shades and can be customized just like ceramics. For this, the low-viscosity Nano-hybrid material GrandioSO Flow and the high-viscosity Nano-hybrid GrandioSO Heavy Flow are particularly well suited, as they provide exact shade matching. Characterization can then follow based on user s capabilities. Easy intra-oral repair While chips in ceramic restorations require extensive treatment, any defects in VOCO s Nano-ceramic Hybrid materials can be repaired intraorally quickly and easily. This is done by roughening the surface of the defect, applying the adhesive and then correcting the situation with a composite restorative such as GrandioSO. Source: Department of Materials for Medical Technology, University of Rostock, 216 3D tomography visualization of the homogeneous distribution of fillers in Grandio blocs. nm sections were prepared using the dual beam technique, viewed under a microscope and combined to create a 3D image. The light blue and dark blue regions represent the glass fillers in 3D. They are surrounded by resin and nano-ceramic particles. Lava, Vita Enamic, and IPS e.max CAD are not registered trademarks of VOCO GmbH.

Grandio blocs UP TO % FASTER THAN LITHIUM DISILICATE BLOCKS Grandio blocs Steps: (Nano-ceramic Hybrid Block) Milling ( 12 mins*) Sprue adjustment and rough finishing (2 mins*) Try in ( mins*) Surface characterization (optional) (8 1 mins*) Crown Surface Treatment = sand blast and application of Ceramic Bond Ready prep for cementation with dual-cure or universal adhesive. Dispense adhesive cement in crown (6 8 mins*) (approx. 2 mins*) Lithium disilicate Block Steps ** : Milling (8 1 mins*) Sprue adjustment and rough finishing/glazing (2 mins*) Try in ( mins*) Firing (approx. 2 mins*) Surface characterization (optional) (8 1 mins*) Seat restoration / clean-up (approx. 6 mins*) Final polish/finishing (if not done extraorally before seating) (approx. mins*) Firing (optional) Try in Crown Surface Treatment based on manufacturer instructions (use of HF-acid) (approx. 12 mins*) (1 min*) (6 8 mins*) Ready prep for cementation manufacturer's instructions for use. Dispense cement in crown (approx. 2 mins*) Seat restoration/clean-up (approx. 6 mins*) Final polish/finishing (optional if needed or not done extraorally before seating) (approx. 8 mins*) Total time: (31 mins*) Total time: (7 89 mins*) TOTAL TIME SAVINGS USING GRANDIO BLOCS = 26 39 MINUTES* NO FIRING OR SINTERING REQUIRED Other Grandio blocs Advantages: Burs last longer Better for antagonist teeth Easy intraoral repair Easy extra- and intraoral characterization 6 * The times listed above are averages to produce a crown ** These steps may vary slightly depending type of material

GRANDIO BLOCS ADMIRA / GRANDIO FUSION DISC Grandio blocs / with Bifix QM ESTHETIC, VERSATILE AND LONG-LASTING Grandio blocs is available in two sizes 12 for small restorations such as inlays 1. mm 12. mm 16 mm Bonded-in Cementation Cementation of Grandio blocs/disc is always carried out using a bonded-in cementation system. Bifix QM, in combination with Futurabond U and Ceramic Bond, is the system of choice for ensuring that the highest standards are also met in this respect. 14L for larger restorations such as crowns 1.4 mm 14.8 mm 12.4 mm Bifix QM is a universal dual-cured cement, which, when used together with the state-of-the-art universal adhesive Futurabond U and the silane coupling agent Ceramic Bond, deliver both excellent mechanical retention and an adhesive interface that will provide extended longevity to the restoration. 18 mm 6 sec. 14. mm 14. mm Average number of restorations per disc: 2-3 98.4 mm 94 mm 1 21 sec. 1 mm 1 mm Two grades of translucency for optimal aesthetics LT Ideal for the anterior region in the shades Grandio blocs: A1, A2, A3, A3., B1, C2, BL : A1, A2, A3, A3. HT Ideal for the posterior region in the shades Grandio blocs: A1, A2, A3, A3. : A1, A2, A3, A3. 11 shades ensure that your patient always receives the restoration which suits him or her best. 7

Grandio blocs / NANO-CERAMIC HYBRID CAD/CAM MATERIAL Indications Crowns, inlays, onlays, veneers Implant supported crowns Presentation REF 6 Kit 2 No. 12 (A2 LT, A2 HT), 3 No. 14L (A2 LT, A2 HT, A1 LT), Bifix QM QuickMix syringe 1 g universal, Futurabond U SingleDose pcs Ceramic Bond bottle ml, Dimanto set, accessories Advantages 86 % filled for enhanced strength and excellent wear resistance Tooth-like elasticity and thermal expansion allows for thinner crown margins Natural esthetics with enhanced color stability and polish retention No firing required for true one appointment dentistry Easy intraoral polishability, characterization and repair Grandio blocs Low translucent (LT) No. 12 No. 14L A1 LT REF 63 REF 618 A2 LT REF 64 REF 619 A3 LT REF 6 REF 62 A3. LT REF 66 REF 621 B1 LT REF 67 REF 622 C2 LT REF 68 REF 623 BL LT REF 69 REF 624 High translucent (HT) No. 12 No. 14L A1 HT REF 612 REF 627 A2 HT REF 613 REF 628 A3 HT REF 614 REF 629 A3. HT REF 61 REF 63 Shade No. 12 No. 14L Mixed* REF 633 REF 634 *(A1 LT, B1 LT, C2 LT, BL LT, A1 HT) Low translucent (LT) Ø 98.4 mm, 1 mm High translucent (HT) Ø 98.4 mm, 1 mm A1 LT REF 6 A1 HT REF 67 A2 LT REF 61 A2 HT REF 68 A3 LT REF 62 A3 HT REF 69 A3. LT REF 63 A3. HT REF 66 VOCO America Inc. 124 Rosemont Drive Suite 14 Indian Land SC 2977 www.vocoamerica.com infousa@voco.com Toll-free phone: 1-888-68-284 Fax: 1-888-849-3989 VC 84 61 US 918 T VOCO is a registered trademark of VOCO GmbH