Advances and Innovations in Breast Reconstruction and Brest Surgery Presented by PCMC plastic surgeons

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Advances and Innovations in Breast Reconstruction and Brest Surgery Presented by PCMC plastic surgeons Options for reconstruction after mastectomy Implants Autologous tissue = from your own body: skin and fat, also known as a flap the goal of breast reconstruction is to restore one or both breasts to near normal shape, appearance, symmetry, and size following mastectomy, lumpectomy or other trauma 106,295 Breast reconstruction procedure in U.S. in 2017(ASPS) o 35% increase since 2000 50% of women undergo reconstruction after mastectomy Brest Reconstruction with Implants Implant based breast reconstruction Modern breast reconstruction began in 1994 with the introduction of silicone breast - Techniques and products have evolved and improved Most common form of reconstruction after mastectomy 2016: >80% of breast reconstructions were reconstructions -Advantages: no new surgery sites/incisions, easier recovery than flap surgery *good reliable results -Disadvantage: s are lifetime devices and may require revision in the future Implant safety established FDA approved silicone s in 2006 but required post approval studies 2011, studies showed no evidence that silicone gel filled breast cause connective tissue disease or reproductive problem -several reports: no evidence that cause systemic disease Local problems common such as -ripping, capsular contracture, rupture -longer ed the more common these issues - leakage range from 2% to 30% over 10 years 10 years after initial breast augmentation, 20% of patients need another operation -80% of the patients are fine at 10 years -You don t need to automatically replace your every 10 years -Since 2011 improved, studier s

Advances in reconstruction Better s and more diverse size Acellular demand matrices (ADMs) -decellularized soft tissue grafts from cadaveric tissue that behave as a collagen scaffold, allowing revascularization and integration into ed tissue -allows partial sub-muscular coverage with the ADM to cover lower part of -allow single stage reconstruction Implant Types Women have options for their individual body shape and goals Silicone vs. Saline Various cohesivities(gumminess), sizes, projections, shape and fill Textured shaped s vs. smooth round s -Gummy bear: anatomic s shaped like a teardrop, textured -Round s create a fuller, more projected look High-strength cohesive (HSC) silicone gel is a breakthrough technology -Strongest type of silicone on the market s remain soft and natural feeling to the touch Single stage vs. Two Stage Single stage (direct to ) -immediate placed -ideal patient: nipple sparing mastectomy with minimal ptosis, good skin quality; no comorbidities -limits in size choice Two Stage -tissue expander placed -second stage expander to expand -safest, more conservative than single stage Subpectoral reconstruction

Mastectomy can result in very thin skin that provides inadequate coverage for an Submuscular placement become the standard of care Advantages -Behind the pectoralis muscle reduces visibility, palpability, ripping and the risk of capsular contracture -Better transition upper pole Disadvantages -Early techniques involving complete submuscular placement resulted in unnatural appealing breast ADMs and partial muscle coverage -Potentially longer recovery time and more initial pain -Flexing muscle may make a breast s move in unnatural way animation deformity Pre-pectoral technique Chest muscle isn t cut and placed over the muscle Advantages -potentially shorter recovery time -less initial pain -greater control of shape and form -no animation deformity

Disadvantage -not all patients are candidates because it requires enough tissue in good condition after a mastectomy -risk of visible ripping of the -less long term data especially regarding capsular contracture -requires ADM wrapping expansive Recovery and revision Full recovery 4~6 weeks -Drains for 7~14 days Reconstruction revisions -Common in mastectomy reconstruction -Address asymmetry, ripping, transition paints -3 months to years after reconstruction Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL) Types of T cell lymphoma that can develop following breast s -within the fibrous capsular around the BIA-ALCL identified most frequently in patients undergoing revision operations for late onset seroma(fluid collection around the ) -textured s -mean 7~8 years after ation Risk is very low; Lifetime risk estimated to be 1:3819 women with textured Implant recovery 1-2 night in the hospital Out of work 2~3 weeks 90~95% Back to full time work 4~5 weeks 95%~98% 6 weeks 99%

Flaps for Breast Reconstruction Flap surgery Technique in plastic surgery where any type of tissue is lifted from a donor site and moved to a recipient site with and intact blood supply Advantage of Flap More life like Implant free Better symmetry after single mastectomy Higher patient satisfication Long term benefit less need for later surgery Disadvantage of Flap Bigger, longer operation Longer hospital stay More difficult reconvery More post op pain Advantage of DIEP Faster recovery Less abdominal wall morbidity Decreased narcotic use post op Shorter hospital stay Fat Necrosis: 5~12% Disadvantage Operation is technically difficult Variable anatomy of perforator; each patient is different Occasional venous congestion requiring additional venous repair Requires microsurgery expertise Flap loss (<1%) Post op course First 24 hours: bed rest, noting to eat Day 1: start eating, up in a chair, transition to oral pain meds Day 2: walking Day 3 or 4: discharge home

DIEP recovery 3-4 nights in the hospital Out of works 3-4 weeks 90~95% Back to fulltime 5~6 weeks 95~98% 8 weeks 99%(a bit slower recovery than ) Oncoplastic reconstruction Immediate reconstruction at the time of lumpectomy -Tumor is first removed -other breast tissue is moved to fill in space left after tumor removal Oncoplastic reconstruction: local tissue rearrangement -often combined with hidden scar lumpectomy -reconstruction done through lumpectomy scar -no added recovery -trade off more scarring for reshaping or resizing breast -may extend option of lumpectomy with larger tumor -recovery only slight longer than lumpectomy alone

(https://westcountyplasticsurgeons.wustl.edu/surgery/breast-surgery/breastreconstruction/reconstruction-for-lumpectomy.html) Benefit patient satisfaction Improved long term comesis Opportunity to improve breast appearance Better margin control around tumor Summary There is no single best type of breast reconstruction The decision is extremely personal and individual The choice of reconstruction should be made once all considerations are explained and understood Implant based breast reconstruction is most popular form of breast reconstruction and safety of s has been stablished Best plan for reconstruction is based on patient s desire quality of skin and patient s characteristic (tumor location, BMI, ptosis, aesthetic goals, need for radiation) Newer lumpectomy approaches address quality of life impact with oncoplastic reconstruction