ATOPIC DERMATITIS IN CHILDREN Simple choice questions 1. Which is the principal cause of atopic dermatitisdevelopment in little age children? A. Psychoemotional factors. B. Habitual antigens. C. Food allergy. D. Fungic allergens. E. Meteorologic factors. 2. Indicate the percentage of the body surface affected in mild form of atopic dermatitis: A. Less than 5% of body surface area B. 5-25% of body surface area C. 25 50% of body surface area D. 50-75% of body surface area E. More than 75% of body surface area 3. Choose the clinical feature that is not characteristic for mild atopic dermatitis: A. Hyperemia, exudation and non-significant excoriation of the skin (affected surface <5%). B. Papules, unique vesicles. C. Mild itching that does not affects the child while sleeping. D. Non-significant lymphadenopathy. E. More than 2 exacerbations per year. 4. Choose the feature that is not characteristic for severe atopic dermatitis: A. Extended body area with exudation and lichenification (more than 50% of body surface). B. Fissures, hemorrhagic crusts. C. Less than 4 exacerbations per year. D. Intensive repeated itching, sleep disturbance. E. Manifested lymphadenopathy. 5. Indicate the manifestation that is not characteristic for acute stage of atopic dermatitis: A. Erythema, papules, vesicles. B. Lichenification, fibrinous papules. C. Erosion. D. Crusts. E. Excoriation. 6. Indicate the group of drugs that is used as first line therapy for atopic dermatitis exacerbations: A. Antihistaminic drugs. B. Antileukotrienes. C. Topic glucocorticosteroids. D. Parenteral antibiotics. E. Immunosuppressants. 7. Choose the drug that is a calcineurin inhibitor: A. Mometasone (Elocom ). B. Pimecrolimus (Elidel ). C. Betamethasone dipropionate (Triderm ). D. Hydrocortisone/Natamycin/Neomycin (Pimafucort ). E. Fexofenadine HCI (Telfast ).
8. Indicate the drug that is from the second generation of antihistaminics and doesn t manifest sedative effect: A. Dimetindene (Fenistil ). B. Quifenadin (Fencarol ). C. Clemastin (Tavegyl ). D. Cetirizine (Parlazin, Zyrtek ). E. Ciproheptadine (Peritol ). 9. Choose the drug that is not indicated for systemic treatment of atopic dermatitis in children: A. First generation antihistaminics that have sedative effect. B. Second generation antihistaminics that does not have sedative effect. C. Antibiotics. D. Calcineurin inhibitors. E. Immunosuppressive drugs. 10. Indicate the side effect that is not attributed to first generation antihistaminics: A. Tachyphylaxis. B. Suppression of the hypothalamic-pituitary-adrenal axis. C. Sleepiness. D. Depression of cognitive functions. E. m-cholinolytic activity. 11. Choose the adverse effect that is not attributed to long-term administration of topical steroids in atopic dermatitis: A. Skin atrophy. B. Erythema, acne, striae. C. Cushing's syndrome. D. Hypertrichosis. E. Secondary skin infection. 12. Choose in what indication is not true for calcineurin inhibitor Pimecrolimus (Elidel) in children with atopic dermatitis: A. Age older than 3 months. B. May be applied on any area of skin. C. Only for cases of atopic dermatitis with secondary skin infection. D. Children with mild or moderate atopic dermatitis. E. Children with severe atopic dermatitis but improvement of the clinical manifestations after a course of topical steroids. 13. In what case the patient must be recommended to limit the sun exposure? A. When he is under the topical treatment with Lanolin. B. When he is under the topical treatment with Pimecrolimus (Elidel ). C. When he is under the topical treatment with Mometasone (Elocom ). D. When he is under the topical treatment with Betamethasone dipropionate (Triderm ). E. When he is under the topical treatment with Metilprednisolon aceponat (Advantan ). Multiple choise 1. More frequently atopic dermatitis is associated with: A. Bronchial asthma. B. Allergic rhinitis.
C. Hemorrhagic vasculitis. D. Cystic fibrosis. E. Pollinosis. 2. The immune response in children with atopy is characterized by: A. Predominant T helper lymphocytes population. B. Total IgE hyperproduction. C. Hyperproduction of IgG antibodies. D. Allergen-specific IgE antibodies hyperproduction. E. Hyperproduction of IgA antibodies. 3. Indicate exogenous factors that can cause atopic dermatitis exacerbation: A. Psychoemotional stress. B. Physical efforts. C. Climate changes. D. Cigarette smoke, different air polluants. E. Food adjuvants and additives. 4. Indicate endogenous factors that play principal role in atopic dermatitis development in children: A. Heredity. B. Dysfunction of suprarenal glands. C. Atopy. D. Hyperreactivity of the skin layers. E. Disturbance of functional and biochemical processes in the skin tissue. 5. Indicate the food that may be as etiological factor for atopic dermatitis in children of the first year of age: A. Cow s milk. B. Breast milk. C. Eggs. D. Fish. E. Vegetables and fruits of red or orange color. 6. Indicate the food products that have a high degree of allergic sensitization: A. Chicken meat. B. Strawberry. C. Green and yellow apples. D. Nuts. E. Cucumbers. 7. Indicate the food products that have a moderate degree of allergic sensitization: A. Cow s milk. B. Pork, turkey meat. C. Tomatoes. D. Pea. E. Corn. 8. Indicate the food products that have a low degree of allergic sensitization: A. Blackcurrant. B. Blackberry. C. Rabbit meat. D. Green colored vegetables.
E. White cherry, white currant, gooseberry. 9. Enumerate clinical manifestations of atopic dermatitis in children: A. Itching. B. Typical morphology and localization of skin lesions. C. Ichthiosis. D. Onset of the disease at an early age. E. Infraorbital fold Dennie Morgan. 10. Enumerate clinical manifestations and evolutional features of atopic dermatitis in children: A. Keratoconus. B. Eczema of mammilla. C. Chronic evolution with exacerbations. D. Familial or personal history of atopy. E. Recurrent conjunctivitis. 11. Enumerate the most common clinical manifestations of atopic dermatitis in children: A. Skin infections. B. Increased level of seric IgE. C. Recurrent conjunctivitis. D. Nonspecific dermatitis on hands and legs. E. Itching at transpiration. 12. Enumerate the most common clinical manifestations of atopic dermatitis in children: A. Focal erythema. B. Positive results of skin allergic tests in the disease remission. C. Cutaneous xerosis. D. Periorbital hyperpigmentation. E. Pityriasis alba (dry white patches). 13. Enumerate compulsory (the most specific) examination indicated for children with atopic dermatitis: A. Complete blood count. B. Serum level of total IgE. C. Skin prick tests. D. Urinalysis. E. Assessment of allergen-specific IgE antibodies. 14. Enumerate examinations that may be indicated for children with atopic dermatitis: A. Skin allergy testing. B. Elimination diet. C. Biochemistry. D. Total protein, blood glucose, creatinine, BUN. E. Lactatdehydrogenase, aspartataminotransferase, alaninaminotransferase, bilirubin and its fractions. 15. Enumerate hospitalization indications for children with atopic dermatitis: A. Exacerbation of the disease with deterioration of general condition. B. Generalized skin lesions associated with secondary infection (bacterial, herpetic). C. Recurrent skin infections. D. Positive skin allergy tests. E. Association of atopic dermatitis with other diseases with severe evolution and nonresponse to standard treatment.