SHANKER N. DIXIT, MD

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Neurology Center of Las Vegas 2480 Professional Ct. Las Vegas, NV 89128 Phone: (702) 405-7100 EDUCATION SHANKER N. DIXIT, MD 1995 Medical: AIIMS, New Delhi, India, DM (Neurology) 1991 Medical: Kasturba Medical College, Manipal, India, M.D. 1986 Undergraduate: Maulana Azad Medical College, New Delhi, India, MBBS POSTGRADUATE TRAINING 2000 2001 Fellowship: Clinical Stroke Fellow, University of Wisconsin Hospital and Clinics, Madison, WI 1999 2000 Fellowship: Clinical Neurophysiology, University of Wisconsin Hospital and Clinics, Madison, WI 1995 1999 Residency: Neurology, University of Wisconsin Hospital, Madison, WI MEDICAL LICENSURE Licensure: State of Nevada CERTIFICATION 2013 Independent Medical Examiner (CIME) 2001 American Board of Psychiatry and Neurology Clinical Neurophysiology 2000 American Board of Psychiatry and Neurology Neurology PROFESSIONAL EXPERIENCE 2007 Present Chief, Division of Neurology, Mountain View Hospital, Las Vegas, NV

2007 Present Medical Director, Neurology Center of Las Vegas, Las Vegas, NV 2004 2006 Physician, Department of Neurology, Gundersen Lutheran, La Crosse, WI 2001 2004 Regional Director, Parkinson s Disease Research, Education and Clinical Center, Las Vegas, NV 2001 2004 Medical Director, Comprehensive Epilepsy Program, Sunrise Hospital and Medical Center, Las Vegas, NV 2001 2004 Staff Neurologist, VA Medical Center, Las Vegas, NV PROFESSIONAL MEMBERSHIPS American Academy of Neurology Clark County Medical Society 2007 - Present Member, Carrier Advisory Committee, Nevada 2004-2006 Member, Medical Advisory Board, Western Wisconsin Technical College, La Crosse, WI AWARDS AND RECOGNITION 2004 Present Adhoc Reviewer, Annals of Internal Medicine 2000 TOPScholar Award for Epilepsy fellows 1999 Outstanding Neurology Resident Award for teaching 1994 ML Soni Award for Best Resident, Neurology, New Delhi, India 1991 Rame Gowda Award for Best Resident, Internal Medicine TEACHING ACTIVITIES April 2005 Gundersen Lutheran Mayo Clinic Physician Assistant Program Seizure Disorders 2004 2006 Faculty, Western Wisconsin Technical College, La Crosse, WI (Video EEG Monitoring) 2004 2006 Faculty, University of Wisconsin, La Crosse, WI (Epilepsy) 2004 2005 Gundersen Lutheran Internal Medicine Residency Program: Core curriculum lectures (Epilepsy), Grand Rounds, bedside teaching. November 2004 Core curriculum lecture Video EEG Monitoring 2001-2004 Assistant Professor of Medicine, Division of Neurology, University of Nevada School of Medicine, Las Vegas, NV UW Medical School Course #622-800, Patients, Doctors, and Society First Year Students, Small Group Leader. UW Medical School Course #622-807, Patients, Doctors, and Society Second Year Students, Small Group Leader.

1999 2000 Resident Lectures EEG and Epilepsy series 7/98 8/98 Medical students bedside teaching and evaluation LECTURES/SPEECHES Understanding Headache: Differentiating Sinus Headache, Tension Headache and Migraines. November 2002, Las Vegas, NV; Medical World Conference CME. Attended by 100 delegates. Understanding Headache: Differentiating Sinus Headache, Tension Headache and Migraines. October 2002, Reno, NJ; Medical World Conference CME. Attended by 60 delegates. Headaches: October 2002; Sierra Health Services Presidents auditorium, Las Vegas, NV. Southwest Medical Associates CME program. Stroke therapy in the new Millennium: September 2002; Sierra Health Services Presidents auditorium, Las Vegas, NV. Southwest Medical Associates CME program. Stroke therapy in the new Millennium: July 2002; Presentation to Kaiser-Permanente primary care physicians. Diagnosis and Management of Epilepsy: March 22, 2002; Sunrise Hospital and Medical Center. Primary care Noon Conference; Continuing Medical Education. ABSTRACTS Dixit SN, Maganti RK, Lotz BP, Slamat S. Gabapentin induced status epilepticus. Poster Presentation. 56 th annual AES meeting, Seattle, WA, Dec 2002. Dulli DA, Dixit SN, Levine RL, Dempsey RJ. Acute ischemic stroke of undetermined etiology in a university hospital. 26 th International Stroke Conference, Fort Lauderdale, FL, Feb 2001. Dixit SN, Sheth RD, Pauli R. Epilepsy in patients with achondroplasia and related disorders with FGFR3 mutation. 54 th annual AES meeting, Los Angeles, CA, Dec 2000. Dixit SN, Dogan S, Brooks BR. Computerized tremor testing in multiple sclerosis: tremor prevalence, type, longitudinal evolution and response to treatment in 185 patients. 50 th annual AAN conference, Minneapolis, MN, March April 1998. Dixit SN, Bushara K, Brooks BR. Epidemic heat stroke in a Midwest community clinical features, complications and sequelae. 48 th Annual AAN conference, San Francisco, CA, March April 1996. PUBLICATIONS Levine RL, Dixit SN, Dulli DA, Khasru MA. Aspirin failures, Clopidogrel added to Aspirin, and secondary stroke prevention in veterans presenting with TIA or mild-to-moderate ischemic stroke. Journal of Stroke and Cerebrovascular Diseases 2003; 12 (1) : 37-43. Dixit SN, Buyan-Dent L, Kurle P, Sheth RD. Status epilepticus associated with cefepime. Neurology 2000; 54 (11): 2153-55.

Dixit SN, Behari M, Ahuja GK. Effect of selegiline on cognitive functions in Parkinson s disease. Journal of the Association of Physicians of India 1999; 47(8): 784-6. Dixit SN, Bushara K, Brooks BR. Epidemic heat stroke in a Midwest community clinical features, complications and sequelae. Wis Med J 1997; 96(5): 39-41. Dixit SN, Jain S, Padma MV, Maheshwari MC. Gabapentin in refractory partial epilepsy a trial in India. Acta Neurol Scand 1996; 9: 259-67. Jain S, Dixit SN, Andrews PI, Radtke R, Maheshwari MC, McNamara JO. Disease expression among probrands with juvenile myoclonic epilepsy and their family members in two population groups. J Epilepsy 1996; 9: 259-67. Dixit SN, Jain S, Bhatia M, Padma MV, Maheshwari MC. Effect of gabapentin on the EEG of patients with refractory partial seizures. J Epilepsy 1995; 8: 338-40. Dixit SN, Sharma S, Behari M, Ahuja GK. Neuroacanthocytosis with pure chorea. J Assoc Physicians India 1993; 41(9): 613. Contributing author, Neurology Pearls. Eds Sutula and Waclawik. Hanley and Belfus, 2000. Sheth RD, Dixit SN. EEG in common epilepsy syndromes. EMedicine (online textbook). Sheth RD, Dixit SN. Early Myoclonic encephalopathy. EMedicine (online textbook). CLINICAL RESEARCH EXPERIENCE 1. A Multi-Center, Double-Blind, Randomized, Placebo-Controlled, Parallel-Group Evaluation of Lamotrigine Adjunctive Therapy in Subjects with Primary Generalized Tonic-Clonic Seizures. Principal Investigator 2. Pregabalin BID Open-Label Add-On-Trial: An Open-Label, Multicenter, Follow-On Study to Determine Long-Term Safety and Efficacy in Patients With Partial Seizures. Principal Investigator. 3. A Phase 2 Randomized, Double-Blind, Placebo-Controlled Dose Finding Study of SNK-860 in Subjects with Diabetic Peripheral Neuropathy. Sub-Investigator. 2016 - Present 4. Axovant A Phase 3, Double-Blind Study of RVT101 Versus Placebo When Added to Existing Donepezil Treatment in Subjects With Mild to Moderate Alzheimer s Disease. Principal Investigator. 2015 - Present 5. Mallinckrodt/MNK Observation Registry of HP Acthar Gel. Principal Investigator. 2016 - Present 6. Kantar Health/Pfizer: Characterization of Neuropathic Pain and its Subtypes in the United States. Principal Investigator. 2016 - Present

7. Neurim AD: Neup-11-AD2 Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Dose-Ranging Study of Piromelatine in patients with Mild Dementia due to Alzheimer's Disease. Principal Investigator 2016 - Present 8. A Phase 3 Multipcenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-group Study to Evaluate the Efficacy and Safety of Aducanumab (BIIB037) in Subjects with Early Alzheimer's Disease. Principal Investigator. 2016 - Present 9. A Phase III, multicenter, randomized, double-blind, placebo-controlled, parallel-group, efficacy and safety study of crenezumab in patients with prodromal to mild Alzheimer's disease. Principal Investigator. 2016 - Present 10. Multicenter, randomized, parallel-group, 78-week-long double-blind (DB), placebocontrolled, study of 2 fixed dose levels of LY3314814 in patients with mild AD and abnormal levels of amyloid, followed by a 78-week-long delayed-start period. Principal Investigator. 2016 - Present 11. Effect of Beta-Ste Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor LY3202626 on Cerebral AV-1451 Tau-Pet in Alzheimer's Disease (AD). Principal Investigator. 2016 - Present. 12. TEV48125-CNS-30050 A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study Companying the Efficacy and Safety of 2 Dose Regiments of Subcutaneous Administration of TEV-48125 Versus Placebo for the Preventive Treatment of Episodic Migraine. Prinicipal Investigator. 2016 - Present 13. TEV48125-CNS-30051 A Multicenter Randomized, Double-Blind, Parallel-Group Study Evaluating Long Term Safety, Tolerability, and Efficacy of subcutaneous Administration of TEV-48125 for the Preventive4 Treatment of Migraine 14. TEV48125-CNS-30049 A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study Comparing the Efficacy and Safety of 2 Dose Regimens of subcutaneous Administration of TEV-48125 Versus Placebo for the Preventive Treatment of Chronic Migraine 15. 1VIT14037 A Double-Blind, Multi-Center, Randomized, Placebo-Controlled Study to Investigate the Efficacy and Safety of Injectafer (Ferric Carboxymaltose) in the Treatment of Restless Legs Syndrome (RLS) 16. COMB157G2301 A randomized, double-blind, double-dummy, parallel-group study comparing the efficacy and safety of ofatumumab versus teriflunomide in patients with relapsing multiple sclerosis