ADVANCES IN SKELETAL MUSCLE BIOLOGY IN HEALTH AND DISEASE CONFERENCE PROGRAM

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ADVANCES IN SKELETAL MUSCLE BIOLOGY IN HEALTH AND DISEASE CONFERENCE PROGRAM WEDNESDAY, March 6, 2019 Reitz Union, University of Florida 12:15-1:15pm Grant-Writing Workshop, Ground Floor Room G330 12:15-12:45 R Grants - Key aspects for a successful grant Room G320 12:15-12:45 K Grants - Key aspects for a successful grant Room G310 12:15-12:45 F Grants - Key aspects for a successful grant 1:15pm Welcome and Opening Remarks, Rion Ballroom (Third Floor Reitz Union) 1:30pm Session Muscle Diseases: Biology & Biomarkers Glenn Walter Melissa Spencer University of California Los Angeles Gillian Butler-Browne Université Pierre et Marie Curie France Gordon Lynch University of Melbourne Australia Pascal Bernatchez University of British Columbia Canada Barry Byrne University of Florida Therapeutics for the Muscular Dystrophies Towards Therapy for OPMD Therapeutic potential of skeletal muscle plasticity for muscle diseases Muscular Dystrophy: a new type of lipid handling disease? Gene Therapy Strategies for NMD: Clinical Considerations

Holmes-Huxley Keynote Lecture 4:45 5:45 6:00pm Reception and Poster Viewing, Grand Ballroom THURSDAY, March 7, 2019 Rion Ballroom, Reitz Union, University of Florida 7:45am Coffee, Tea, and Pastries, Rion Ballroom West Foyer 8:00am Session Mechanisms of Muscle Wasting Andrew Judge Marco Sandri Venetian Institute of Molecular Medicine Italy Gerald Supinski University of Kentucky College of Medicine Jason Doles Mayo Clinic Novel Players in Muscle Wasting A Stimulating Experience: Magstim Assessment of Muscle in ICU Patients Microenvironment Alterations in Wasting Skeletal Muscle 10:00am 10:30am Session Muscle Force Transmission and EC-Coupling Lee Sweeney Susan Hamilton Baylor College of Medicine Coen Ottenheijm University of Arizona Feliciano Protasi Heat Sensitivity and Malignant Hyperthermia Store-Operated Ca2+ Entry in Skeletal Muscle: Where?

Università degli Studi G. d Annunzio Chieti-Pescara Italy 12:30-2:30pm Poster Session I Grand Ballroom Beverages and boxed lunches provided 2:30pm Session Nutrition and Muscle Metabolism Greg Cartee University of Michigan Anastasia (Natasha) Kralli Johns Hopkins University School of Medicine Mechanisms for Post-Exercise Muscle Glucose Uptake Regulatory networks for exercise-induced oxidative The metabolism adaptations Yen-Chun (Charly) Lai Skeletal Muscle SIRT3 in Metabolic Syndrome-Associated Indiana University Pulmonary Hypertension Purdue University Indianapolis 3:55-4:25pm Paul Coen AdventHealth Mitochondrial Energetics and fuel metabolism in Sarcopenia Pre- and post-doctoral trainee data blitz (2 min presentations with no questions) 7:00pm Dinner at the Swamp Restaurant; The speakers will be dining at the Swamp Restaurant and we encourage all attendees to dine there also so that informal interactions can continue.

FRIDAY, March 8, 2019 Rion Ballroom, Reitz Union, University of Florida 7:45am Coffee, Tea, and Pastries, Rion Ballroom West Foyer 8:00am Session Muscle Hypertrophy and Mechanotransduction Chris Fry University of Texas Medical Branch Gabrielle Kardon University of Utah Lorenzo Puri Sanford Burnham Prebys Medical Discovery Institute Mary Baylies Sloan Kettering Institute Aging Muscle Growth and Plasticity Molecular and Cellular Regulation of Muscle Regeneration MyoD re-wiring of 3D chromatin architecture during nuclear reprogramming toward myogenesis Coordination of Nuclear Scaling and Muscle Cell Size During Development and in Disease 10:00-10:30am 10:30am Session Skeletal Muscle Aging: Metabolism and Function Dawn Lowe University of Minnesota Charlotte Peterson University of Kentucky Brian McDonagh NUI Galway Ireland Carlos Moraes University of Miami Sex as a Biological Variable: When Estradiol and Estrogen Receptors Affect Skeletal Muscle Physiology Resident Macrophages in Skeletal Muscle Adaption to Physical Activity and Aging DNA editing enzymes as tools to eliminate mutant mtdna

12:30-2:00pm Poster Session II Grand Ballroom Beverages and boxed lunches provided 2:00pm Session Mitochondria and Redox Biology Christopher Perry York University Canada Chris Ward University of Maryland Malcolm Jackson University of Liverpool England Terence Ryan University of Florida Targeting mitochondrial bioenergetics to treat muscle weakness in Duchenne muscular dystrophy Redox Tunes the Cytoskeleton to Regulate Function Role of Local Denervation in Disruption of Redox Regulation During Aging Mitochondria and Ischemic Muscle Injury 4:00pm Farewell