Bio-mimetic, powerful moisturizing, and High functional Mild ingredients Made by NFC Sales Team Published date : January. 2018

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Bio-mimetic Gel Base Bio-mimetic, powerful moisturizing, and High functional Mild ingredients Made by NFC Sales Team Published date : January. 2018

Unique Efficacy of Bio-mimetic Gel Base This bio-mimetic lipid component and other functional ingredients can lead to an enhancement of skin barrier, very powerful moisturizing and the soothing effects. Substance Main Component (INCI Name) Main Efficacy Phospholipid Ceramide NP, Cholesterol Main components of the lipid membrane of skin cells. Protective ability from external stimulus by enhancing the skin barrier. Evaporation suppression. Anti inflammation/treating atopic dermatitis etc. Unsaturated fatty acid Olea Europaea (Olive) Fruit Oil Butyrospermum Parkii (Shea) Butter, Squalane To give Skin-conditioning effectiveness. Suppression of moisture evaporation from skin. To give skin-texture of natural ingredient.

The safe ingredients of Bio-mimetic Gel Base Composition No. Component (INCI) Origin Source EWG Safety Grade 1 Glycerin Plant 1 2 Caprylic/Capric Triglyceride Plant 2 3 Olea Europaea (Olive) Fruit Oil Plant 1 4 Hydrogenated Lecithin Plant 2 5 Butyrospermum Parkii (Shea) Butter Plant 1 6 Squalane Plant 1 7 Cholesterol Micro-organism 1 8 Ceramide NP Micro-organism 1 9 Phytosphingosine Micro-organism 1 10 1,2-Hexanediol Synthetic 1 11 Water - 1 Accordking to the EWG s Skin Deep, the level of all components are within 2. More than 98% of the components are natural origin. Good Safety, Less Irritation.

Skin friendly products = Bio-mimetic Gel Base Why is the stratum corneum important? Skin has three layers : SC(Stratum Corneum) The epidermis, and The dermis. SC has lamellar structure such as below brick. The stratum corneum is the outermost layer of epidermis, consisting of dead cells. The stratum corneum functions to form a barrier to protect underlying tissue from infection, helps keep the skin hydrated by absorbing water in air and maintains homeostasis of skin. SC Epidermis 1 : CERAMIDE 2 : CHOLESTEROL 3 : FREE FATTY ACID Dermis 1 2 3 <Skin structure diagram> Ref) J Chromato B, Biomed Appl 1994, 656(1):65-71

Skin friendly products = Bio-mimetic Gel Base Lipid composition of SC Ceramide : 40% Cholesterol : 25% Free fatty acid : 25% Free Sphingolipids : (nmol/mg protein) Phytosphingosine : 2.8 Sphingosine : 1.2 Sphiganine : 0.5 Such as cement between bricks, lipid ingredients facilitate cellular adhesion by linking adjacent cells within this epidermal layer. If SC lacks its component, what would happen? 1. The holes can be occur between skin cells. (The depletion of these lipids results in a disruption of the barrier function of the skin.) 2. This hole is a causative factor of skin moisture loss and infection. 3. Consequently, it can cause various skin diseases. The fine holes can be discovered by weakening the links between cells. ref ) Joke A. Bouwstra and Gert S. Gooris, The Open Dermatology Journal, 2010, 4, 10-13

Suitability of Bio-mimetic Gel Base for skin Technology applied for Bio-mimetic Gel Base TM (NFC developed) Most functional ingredients such as Phospholipids and Sphingolipids are insoluble. To add high contents of these functional ingredients stably in cosmetics, NFC use our patented technology. SEM (x1000) SEM (x1000) Sphingolipid can be recrystallized due to its own crystal structure. NFC s technology can help dissolve its SEM (x7000 ) SEM (x7000 ) crystalline structure easily by making it amorphous. You can contain high active ingredient content very stably. Pure Ceramide 3 NFC product

Characters of Bio-mimetic Gel Base Bio-mimetic Gel Base TM (NFC developed) Bio-Mimetic components. Powerful moisturizing function, skin-barrier enhancement, maintenance of homeostasis of skin. Bio-mimetic components in Bio-mimetic Gel Base TM Component (INCI) Cholesterol, Phytosphingosine Ceramide NP Olea Europaea (Olive) Fruit Oil Butyrospermum Parkii (Shea) Butter Character Main component of skin cells lipid membrane. Its multi-lamellar structure helps retain sufficient moisture in skin. Prevents Atopic eczema Contains Vitamin E and provitamin. Removes toxins and metabolic wastes and helps prevent skin aging. Has high fatty acid content and it is very suitable for dry skin care. Has tocopherol, which is a family of vitamin E and powerful antioxidant substance. Squalane Is derived from fermented sugarcane. Is very skin friendly due to biomimetic structure.

THANK YOU Main Office : 인천연수구갯벌로 145번길 15-8 (15-8 Gaetbeol-ro 145beon-gil, Yeonsu-gu, Incheon City) Contact Number : Tel (+82)-32-831-1091 / Fax (+82)-32-831-1095 Contact Person : 영업부송재근과장 (Eric from Sales Department) E-mail : eric.song@nfccos.com Homepage : www.nfccosmetic.co.kr