BC Methadone Maintenance System: Performance Measures 2011/2012 Appendix A: Report Figures and Data

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Transcription:

BC Methadone Maintenance System: Performance Measures 2011/2012 Pharmaceutical Services Division & Population and Public Health Division British Columbia Ministry of Health February 2013

You may download the full report from: http://www.health.gov.bc.ca/pho/pdf/methadone-2011-12.pdf

Table of Contents REPORT DATA.... 1 Figure 2...1 Figure 3...2 Figure 4...3 Figure 5...4 Figure 6...5 Figure 7...7 Figure 8...8 Figure 10...10 Figure 11...11 Figure 12...13 Figure 13...15 Figure 14...16 i

Figure 2 Cumulative Patient Count 16,000 14,000 12,000 10,000 8,000 6,000 4,000 2,000 - Methadone Maintenance Patients by Health Authority, 2001/2002 to 2011/2012 01 Interior 02 Fraser 03 Vancouver Coastal 04 Vancouver Island 05 Northern BC Total Patient Health Authority Fiscal Year Total Patients 01 Interior 2001/2002 826 2002/2003 850 2003/2004 886 2004/2005 940 2005/2006 996 2006/2007 1,094 2007/2008 1,128 2008/2009 1,317 2009/2010 1,512 2010/2011 1,755 2011/2012 1,984 02 Fraser 2001/2002 2,929 2002/2003 3,072 2003/2004 3,072 2004/2005 3,147 2005/2006 3,161 2006/2007 3,336 2007/2008 3,520 2008/2009 3,983 2009/2010 4,495 2010/2011 5,246 2011/2012 5,810 03 Vancouver Coastal 2001/2002 2,858 2002/2003 3,048 2011 / 2012 Patient Health Authority Fiscal Year Total Patients 03 Vancouver Coastal 2003/2004 3,080 (continued) 2004/2005 3,151 2005/2006 3,251 2006/2007 3,349 2007/2008 3,530 2008/2009 3,784 2009/2010 3,902 2010/2011 4,108 2011/2012 4,318 04 Vancouver Island 2001/2002 1,544 2002/2003 1,582 2003/2004 1,536 2004/2005 1,659 2005/2006 1,701 2006/2007 1,753 2007/2008 1,860 2008/2009 2,034 2009/2010 2,202 2010/2011 2,443 2011/2012 2,538 05 Northern 2001/2002 248 2002/2003 220 2003/2004 200 2004/2005 215 2005/2006 233 2006/2007 255 2007/2008 294 2008/2009 320 2009/2010 333 2010/2011 345 2011/2012 406 BC Total 2001/2002 7,755 2002/2003 8,029 2003/2004 7,967 2004/2005 8,318 2005/2006 8,563 2006/2007 8,998 2007/2008 9,466 2008/2009 10,372 2009/2010 11,385 2010/2011 12,703 2011/2012 13,894 1

Figure 3 New Patient Count New Methadone Maintenance Patients by Health Authority, BC, 2001/2002 to 2011/2012 2,500 2,000 1,500 1,000 500-01 Interior 02 Fraser 03 Vancouver Coastal 04 Vancouver Island 05 Northern BC Total Patient Health Authority Fiscal Year New Patients 01 Interior 2001/2002 168 2002/2003 131 2003/2004 168 2004/2005 189 2005/2006 221 2006/2007 232 2007/2008 198 2008/2009 255 2009/2010 261 2010/2011 328 2011/2012 390 02 Fraser 2001/2002 504 2002/2003 426 2003/2004 361 2004/2005 448 2005/2006 428 2006/2007 473 2007/2008 446 2008/2009 561 2009/2010 558 2010/2011 911 2011/2012 879 03 Vancouver Coastal 2001/2002 522 2002/2003 454 2011 / 2012 Patient Health Authority Fiscal Year New Patients 03 Vancouver Coastal 2003/2004 391 (continued) 2004/2005 383 2005/2006 437 2006/2007 451 2007/2008 471 2008/2009 472 2009/2010 570 2010/2011 573 2011/2012 597 04 Vancouver Island 2001/2002 286 2002/2003 218 2003/2004 204 2004/2005 269 2005/2006 236 2006/2007 279 2007/2008 255 2008/2009 315 2009/2010 271 2010/2011 347 2011/2012 310 05 Northern 2001/2002 28 2002/2003 29 2003/2004 23 2004/2005 38 2005/2006 45 2006/2007 53 2007/2008 51 2008/2009 59 2009/2010 62 2010/2011 59 2011/2012 88 BC Total 2001/2002 1,508 2002/2003 1,258 2003/2004 1,147 2004/2005 1,327 2005/2006 1,367 2006/2007 1,488 2007/2008 1,421 2008/2009 1,662 2009/2010 1,722 2010/2011 2,218 2011/2012 2,264 2

Figure 4 Prescriber Count Notes: 500 450 400 350 300 250 200 150 100 50 0 Methadone Maintenance Program Active Prescribers by Health Authority, BC, 2001/2002 to 2011/2012 01 Interior 02 Fraser 03 Vancouver Coastal 04 Vancouver Island 05 Northern BC Total - Data obtained August 21, 2012 from Health Ideas/PharmaNet database - Methadone prescribers counted if they prescribed at least one PharmaCare accepted claim for methadone maintanence (PINS: 66999990, 66999991, 66999992, 66999993) during the fiscal year - Precribers limited to MSP prescribers with valid College of Physicians and Surgeons of BC licence number Health Authority Fiscal Year Number of MMP Prescribers 01 Interior 2001/2002 52 2002/2003 50 2003/2004 49 2004/2005 48 2005/2006 53 2006/2007 44 2007/2008 22 2008/2009 18 2009/2010 25 2010/2011 25 2011/2012 25 02 Fraser 2001/2002 108 2002/2003 110 2003/2004 108 2004/2005 127 2005/2006 121 2006/2007 91 2007/2008 64 2008/2009 65 2011 / 2012 Health Authority Fiscal Year Number of MMP Prescribers 02 Fraser (continued) 2009/2010 66 2010/2011 66 2011/2012 73 03 Vancouver Coastal 2001/2002 159 2002/2003 156 2003/2004 168 2004/2005 172 2005/2006 184 2006/2007 189 2007/2008 151 2008/2009 143 2009/2010 147 2010/2011 166 2011/2012 168 04 Vancouver Island 2001/2002 77 2002/2003 74 2003/2004 83 2004/2005 84 2005/2006 64 2006/2007 82 2007/2008 49 2008/2009 44 2009/2010 48 2010/2011 43 2011/2012 44 05 Northern 2001/2002 23 2002/2003 21 2003/2004 25 2004/2005 29 2005/2006 23 2006/2007 25 2007/2008 20 2008/2009 20 2009/2010 19 2010/2011 20 2011/2012 22 BC Total 2001/2002 413 2002/2003 402 2003/2004 432 2004/2005 454 2005/2006 442 2006/2007 425 2007/2008 296 2008/2009 284 2009/2010 297 2010/2011 317 2011/2012 327 3

Figure 5 Pharmacist Count 4 3,000 2,500 2,000 1,500 1,000 500 - Methadone Maintenance Pharmacists by Health Authority, BC, 2001/2002 to 2011/2012 01 Interior 02 Fraser 03 Vancouver Coastal 04 Vancouver Island 05 Northern BC Total Pharmacy Health Authority Fiscal Year Total MMP Pharmacists 01 Interior 2001/2002 207 2002/2003 219 2003/2004 265 2004/2005 287 2005/2006 341 2006/2007 356 2007/2008 373 2008/2009 424 2009/2010 453 2010/2011 481 2011/2012 527 02 Fraser 2001/2002 263 2002/2003 326 2003/2004 465 2004/2005 563 2005/2006 608 2006/2007 672 2007/2008 730 2008/2009 786 2009/2010 838 2010/2011 902 2011/2012 991 2011 / 2012 Pharmacy Health Authority Fiscal Year Total MMP Pharmacists 03 Vancouver Coastal 2001/2002 228 2002/2003 301 2003/2004 415 2004/2005 484 2005/2006 561 2006/2007 584 2007/2008 594 2008/2009 662 2009/2010 697 2010/2011 741 2011/2012 812 04 Vancouver Island 2001/2002 187 2002/2003 207 2003/2004 258 2004/2005 307 2005/2006 343 2006/2007 371 2007/2008 396 2008/2009 455 2009/2010 467 2010/2011 490 2011/2012 499 05 Northern 2001/2002 59 2002/2003 78 2003/2004 90 2004/2005 105 2005/2006 122 2006/2007 111 2007/2008 129 2008/2009 136 2009/2010 143 2010/2011 163 2011/2012 178 BC Total 2001/2002 875 2002/2003 1,023 2003/2004 1,340 2004/2005 1,534 2005/2006 1,706 2006/2007 1,812 2007/2008 1,924 2008/2009 2,100 2009/2010 2,184 2010/2011 2,315 2011/2012 2,546

Figure 6 Methadone Maintenance Pharmacies by Health Authority, BC, 2001/2002 to 2011/2012 700 Notes: 600 - Data obtained September 2, 2011 from Health Ideas/PharmaNet database 500 400 300 200 100 0 2011 / 2012 Pharmacies Count - Methadone pharmacies counted if they filled at least one PharmaCare accepted claim for methadone maintanence (PINS: 66999990, 66999991, 66999992, 66999993) during the fiscal year - Witnessed Ingestion Pharmacies counted if filled claim for specific PINs for methadone taken on-site (PINs: 66999990, 66999993) - Carry Home Pharmacies counted if filled claim for specific PINs for methadone taken off-site (PINs: 66999991, 66999992) - Population figures includes only pharmacies active in PharmaNet during the fiscal year 01 Interior 02 Fraser 03 Vancouver Coastal 04 Vancouver Island 05 Northern BC Total Pharmacy Health Authority Fiscal Year MMP Pharmacies per 100 Pharmacies Total MMP Pharmacies 01 Interior 2001/2002 31.91 60 2002/2003 34.2 66 2003/2004 37.95 74 2004/2005 38.92 79 2005/2006 42.45 90 2006/2007 41.28 90 2007/2008 42.04 95 2008/2009 42.98 101 2009/2010 42.62 104 2010/2011 43.55 108 2011/2012 48.19 120 02 Fraser 2001/2002 26.5 75 2002/2003 30.34 88 2003/2004 36.95 109 2004/2005 40.19 127 2005/2006 42.86 141 2006/2007 44.09 153 2007/2008 45.14 167 2008/2009 42.82 176 2009/2010 45.43 199 2010/2011 47.92 207 2011/2012 48.37 222 continued on next page... 5

Figure 6 data continued from previous page Pharmacy Health Authority Fiscal Year MMP Pharmacies per 100 Pharmacies Total MMP Pharmacies 03 Vancouver Coastal 2001/2002 25.75 69 2002/2003 31.62 86 2003/2004 36.79 103 2004/2005 36.77 107 2005/2006 38.24 117 2006/2007 37.85 120 2007/2008 36.47 120 2008/2009 38.3 131 2009/2010 36.44 133 2010/2011 39.5 141 2011/2012 44.47 165 04 Vancouver Island 2001/2002 27.46 53 2002/2003 27.64 55 2003/2004 33.33 68 2004/2005 36.02 76 2005/2006 39.44 84 2006/2007 41.44 92 2007/2008 42.73 97 2008/2009 43.88 104 2009/2010 43.75 105 2010/2011 46.19 109 2011/2012 44 110 05 Northern 2001/2002 22.89 19 2002/2003 23.81 20 2003/2004 25.84 23 2004/2005 29.21 26 2005/2006 28.57 26 2006/2007 29.35 27 2007/2008 34.04 32 2008/2009 35.79 34 2009/2010 36.84 35 2010/2011 40.66 37 2011/2012 44.09 41 BC Total 2001/2002 27.19 276 2002/2003 30.35 315 2003/2004 35.47 377 2004/2005 37.39 415 2005/2006 39.79 458 2006/2007 40.3 482 2007/2008 41.01 511 2008/2009 41.36 546 2009/2010 41.68 576 2010/2011 44.13 602 2011/2012 46.27 658 6

Figure 7 Provincial Government and PharmaCare Methadone Expenditures, BC, 2001/2002 to 2011/2012 Total Costs $45,000,000 $40,000,000 $35,000,000 $30,000,000 $25,000,000 $20,000,000 $15,000,000 $10,000,000 $5,000,000 0 2011 / 2012 $3,500 $3,000 $2,500 $2,000 $1,500 $1,000 $500 0 Average PharmaCare Paid Average BC Cost Total BC Cost Total PharmaCare Paid Average Cost Per Patient Notes: - Data obtained September 2, 2011 from Health Ideas/PharmaNet database - Data includes all PharmaCare accepted claims for methadone maintanence (PINS: 66999990, 66999991, 66999992, 66999993) during the fiscal year - BC Costs include total cost to PharmaCare, patients, or other 3rd party insurers of ingredients, dispensing fees, and interaction fees for witnessed ingestion - PharmaCare Paid costs include on costs to PharmaCare for ingredients, dispensing fees, and interaction fees - Median costs include an estimate of interaction fees for individual patients; actual interaction fee is paid in bulk to pharmacies Fiscal Year Patients Average PharmaCare Paid Total PharmaCare Paid Average BC Cost Total BC Cost 2001/2002 7,755 $2,147 $16,646,864 $2,377 $18,429,806 2002/2003 8,029 $2,592 $20,811,537 $2,917 $23,418,357 2003/2004 7,967 $2,674 $21,303,616 $2,963 $23,604,168 2004/2005 8,318 $2,722 $22,642,611 $3,034 $25,237,224 2005/2006 8,563 $2,751 $23,555,163 $3,088 $26,442,849 2006/2007 8,998 $2,782 $25,029,135 $3,138 $28,236,952 2007/2008 9,466 $2,958 $27,999,245 $3,325 $31,477,889 2008/2009 10,372 $2,747 $28,490,085 $3,110 $32,255,307 2009/2010 11,385 $2,826 $32,170,225 $3,187 $36,282,537 2010/2011 12,703 $2,837 $36,032,632 $3,214 $40,826,395 2011/2012 13,894 $2,899 $40,276,077 $3,301 $45,867,722 7

Figure 8a Medical Services Plan Methadone Expenditures for Methadone Maintenance Treatment Only, BC Total, 2001/2002 to 2011/2012 Figure 8b Medical Services Plan Methadone Expenditures for Methadone Maintenance Treatment Only, by Health Authority, 2001/2002 to 2011/2012 Million $ 14.00 12.00 10.00 8.00 6.00 4.00 Million $ 5.00 4.50 4.00 3.50 3.00 2.50 2.00 1.50 1.00 0.50 Interior Fraser Vancouver Coastal Vancouver Island Northern 2.00 0.00 2011 / 2012 2011 / 2012 Notes: 1. Data includes MSP fee-for-service services by date of service for selected Fee item 39 - METHADONE OR BUPRENORPHINE/NALOXONE TREATMENT ONLY for fiscal years 2001/2002 to 2011/2012, paid to December 31, 2012. 2. Services exclude visit/procedural premiums, no charge referrals and tray fees (but corresponding expenditures are reported). 3. Data exclude third party billings (e.g, ICBC, WCB). Practitioner Health Authority Fiscal Year Expenditure 1 - Interior 2001/2002 $661,605 2002/2003 $577,081 2003/2004 $624,929 2004/2005 $664,869 2005/2006 $732,711 2006/2007 $821,042 2007/2008 $865,421 2008/2009 $1,023,030 2009/2010 $1,174,458 2010/2011 $1,362,612 2011/2012 $1,618,047 2 - Fraser 2001/2002 $1,185,860 2002/2003 $1,184,806 2003/2004 $1,234,185 2004/2005 $1,288,085 2005/2006 $1,101,002 2006/2007 $1,244,313 2007/2008 $1,321,416 2008/2009 $1,432,659 2009/2010 $1,799,963 2010/2011 $2,040,644 2011/2012 $2,865,334 Practitioner Health Authority Fiscal Year Expenditure 3 - Vancouver Coastal 2001/2002 $2,613,232 2002/2003 $3,057,189 2003/2004 $2,556,576 2004/2005 $2,540,455 2005/2006 $2,734,901 2006/2007 $2,792,363 2007/2008 $3,022,183 2008/2009 $3,322,460 2009/2010 $4,054,611 2010/2011 $4,738,335 2011/2012 $4,834,282 4 - Vancouver Island 2001/2002 $1,014,368 2002/2003 $1,178,390 2003/2004 $1,211,725 2004/2005 $1,369,014 2005/2006 $1,444,773 2006/2007 $1,483,609 2007/2008 $1,677,994 2008/2009 $1,823,050 2009/2010 $2,059,432 2010/2011 $2,263,307 2011/2012 $2,360,815 continued on next page... 8

Figure 8 data continued from previous page Practitioner Health Authority Fiscal Year Expenditure 5 - Northern 2001/2002 $113,187 2002/2003 $187,761 2003/2004 $83,746 2004/2005 $59,125 2005/2006 $27,784 2006/2007 $46,661 2007/2008 $58,275 2008/2009 $66,370 2009/2010 $85,914 2010/2011 $82,647 2011/2012 $92,997 99 - Unknown 2003/2004 $4,397 2005/2006 $810 2009/2010 $6,447 BC Total 2001/2002 $5,588,252 2002/2003 $6,185,227 2003/2004 $5,715,559 2004/2005 $5,921,548 2005/2006 $6,041,981 2006/2007 $6,387,988 2007/2008 $6,945,289 2008/2009 $7,667,569 2009/2010 $9,180,825 2010/2011 $10,487,546 2011/2012 $11,771,476 9

/ / / / / / / / / / / Figure 10 % adherence to minimum effective stabilization dose guideline Adherence to Minimum Effective Dose Guideline, by Health Authority, BC, 2001/2002 to 2011/2012 65% 60% 55% 50% 45% 40% 35% Patient Health Authority 2002 2001 2003 2002 2004 2003 01 Interior 02 Fraser 2005 2004 2006 2005 03 Vancouver Coastal Fiscal Year 2007 2006 2008 2007 2009 2008 2010 2009 2011 2010 2012 2011 04 Vancouver Island 05 Northern BC Total % Adherance to Minimum Effective Dose Guidelines 01 Interior 2001/2002 50.00% 2002/2003 54.16% 2003/2004 55.46% 2004/2005 56.14% 2005/2006 57.04% 2006/2007 59.09% 2007/2008 62.42% 2008/2009 62.74% 2009/2010 62.56% 2010/2011 62.62% 2011/2012 58.90% 02 Fraser 2001/2002 40.06% 2002/2003 40.75% 2003/2004 45.99% 2004/2005 46.51% 2005/2006 49.35% 2006/2007 52.68% 2007/2008 54.54% 2008/2009 55.88% 2009/2010 57.17% 2010/2011 55.69% 2011/2012 52.35% Patient Health Authority 03 Vancouver Coastal Fiscal Year % Adherance to Minimum Effective Dose Guidelines 2001/2002 44.46% 2002/2003 45.47% 2003/2004 48.81% 2004/2005 48.59% 2005/2006 49.91% 2006/2007 52.56% 2007/2008 51.38% 2008/2009 52.31% 2009/2010 52.58% 2010/2011 52.49% 2011/2012 49.35% 04 Vancouver Island 2001/2002 47.45% 2002/2003 45.71% 2003/2004 47.80% 2004/2005 49.09% 2005/2006 52.48% 2006/2007 54.81% 2007/2008 55.77% 2008/2009 55.85% 2009/2010 57.54% 2010/2011 59.27% 2011/2012 57.74% 05 Northern 2001/2002 39.66% 2002/2003 40.43% 2003/2004 44.00% 2004/2005 41.18% 2005/2006 47.50% 2006/2007 51.02% 2007/2008 56.28% 2008/2009 55.25% 2009/2010 56.51% 2010/2011 55.14% 2011/2012 53.12% BC Total 2001/2002 44.00% 2002/2003 44.68% 2003/2004 48.26% 2004/2005 48.81% 2005/2006 51.12% 2006/2007 53.75% 2007/2008 54.76% 2008/2009 55.55% 2009/2010 56.44% 2010/2011 56.20% 2011/2012 53.35% 10

Figure 11 Percentage of People Started on Methadone Maintenance Treatment Retained at 12 Months, by Health Authority, BC, 2001/2002 to 2010/2011 BC Total Vancouver Coastal 60% 60% Percent retained 50% 40% 30% Percent retained 50% 40% 30% 20% 20% 60% Interior 60% Vancouver Island Percent retained 50% 40% 30% Percent retained 50% 40% 30% 20% 20% 60% Fraser Percent retained 50% 40% 30% 20% 01 / 2002 02 / 2003 03 / 2004 04 / 2005 05 / 2006 06 / 2007 07 / 2008 08 / 2009 09 / 2010 10 / 2011 60% Northern Percent retained 50% 40% 30% 20% continued on next page... 11

Figure 11 data continued from previous page Notes: - Data obtained August 30-31 2011 from Health Ideas/PharmaNet database & September 6, 2011 from Hospital Discharge Abstract Database (DAD) - Hospital Admissions are measured as unique records of entry into DAD - 100 Person years calculated as days of methadone maintanence treatment divided by 36,500 - Hospital costs for years 2001/02 to 2003/04 apply cost per weighted case of $5,010 to resource intensity weights (RIW) of each admission; this is the 2008/09 cost per weighted case - Hospital costs for years 2004/05 to 2009/10 apply cost per weighted case of $5,390 to resource intensity weights (RIW) of each admission; this is the 2009/10 cost per weighted case - 2009/10 RIWs not available for years 2001/02 to 2003/04 - Median cost excluded because fewer than 50% of patients admitted to hospitals during methadone maintanence * 2009/10 figures may be incomplete because patients admitted to hospitals in 2009/10 but not discharged until 2010/11 will not appear in 2009/10 data Patient Health Authority Fiscal Year Retention After 1 Year (%) 01 Interior 2001/2002 37% 2002/2003 43% 2003/2004 39% 2004/2005 42% 2005/2006 39% 2006/2007 43% 2007/2008 42% 2008/2009 50% 2009/2010 46% 2010/2011 43% 02 Fraser 2001/2002 42% 2002/2003 45% 2003/2004 45% 2004/2005 41% 2005/2006 42% 2006/2007 44% 2007/2008 44% 2008/2009 46% 2009/2010 47% 2010/2011 42% 03 Vancouver Coastal 2001/2002 44% 2002/2003 46% 2003/2004 43% 2004/2005 39% 2005/2006 39% 2006/2007 42% 2007/2008 35% 2008/2009 39% 2009/2010 38% 2010/2011 38% Patient Health Authority Fiscal Year Retention After 1 Year (%) 04 Vancouver Island 2001/2002 48% 2002/2003 46% 2003/2004 46% 2004/2005 48% 2005/2006 43% 2006/2007 50% 2007/2008 50% 2008/2009 49% 2009/2010 52% 2010/2011 51% 05 Northern 2001/2002 36% 2002/2003 40% 2003/2004 30% 2004/2005 47% 2005/2006 34% 2006/2007 41% 2007/2008 44% 2008/2009 39% 2009/2010 41% 2010/2011 37% BC Total 2001/2002 43% 2002/2003 45% 2003/2004 43% 2004/2005 42% 2005/2006 41% 2006/2007 44% 2007/2008 41% 2008/2009 45% 2009/2010 44% 2010/2011 42% 12

Figure 12 Hospitalizations per 100 Person Years During Methadone Maintenance, by Health Authority, BC,, 2001/2002 to 2010/2011 90 No. of hospitalisations per 100 person years 80 70 60 50 40 30 20 10-01 Interior 02 Fraser 03 Vancouver Coastal 04 Vancouver Island 05 Northern BC Total Notes: - Data obtained August 30-31 2011 from Health Ideas/PharmaNet database - Deaths of all causes recorded within 30 days of episode of methadone maintanence therapy - 100 Person years calculated as days of methadone maintanence treatment divided by 36,500 Patient Health Authority Fiscal Year Admissions per 100 Person Years Total Hospital Admissions 01 Interior 2001/2002 38 34 2002/2003 32 66 2003/2004 33 89 2004/2005 46 154 2005/2006 40 173 2006/2007 44 227 2007/2008 44 256 2008/2009 38 269 2009/2010 32 266 2010/2011 32 309 02 Fraser 2001/2002 24 78 2002/2003 24 191 2003/2004 29 278 2004/2005 27 313 2005/2006 30 394 2006/2007 32 482 2007/2008 27 455 2008/2009 28 548 2009/2010 26 589 2010/2011 26 691 continued on next page... 13

Figure 12 data continued from previous page Patient Health Authority Fiscal Year Admissions per 100 Person Years Total Hospital Admissions 03 Vancouver Coastal 2001/2002 35 118 2002/2003 29 248 2003/2004 33 359 2004/2005 37 466 2005/2006 35 496 2006/2007 38 603 2007/2008 35 649 2008/2009 35 702 2009/2010 31 724 2010/2011 31 811 04 Vancouver Island 2001/2002 35 62 2002/2003 27 113 2003/2004 33 165 2004/2005 34 216 2005/2006 31 232 2006/2007 38 321 2007/2008 36 360 2008/2009 30 344 2009/2010 28 367 2010/2011 25 348 05 Northern 2001/2002 35 7 2002/2003 71 32 2003/2004 78 44 2004/2005 39 30 2005/2006 48 44 2006/2007 46 55 2007/2008 57 82 2008/2009 56 92 2009/2010 38 76 2010/2011 41 90 BC Total 2001/2002 31 299 2002/2003 28 650 2003/2004 33 935 2004/2005 34 1,179 2005/2006 34 1,339 2006/2007 37 1,688 2007/2008 34 1,802 2008/2009 33 1,955 2009/2010 29 2,022 2010/2011 28 2,249 14

Figure 13 All-cause Mortality During Methadone Maintenance Treatment, BC Total, 2001/2002 to 2011/2012 120 2 100 80 60 40 20 1.8 1.6 1.4 1.2 1 0.8 0.6 0.4 0.2 0 0 No. of total deaths per year 2011 / 2012 No. of deaths per 100 person years Annual # of Total Deaths Deaths per 100 Person Years Notes: - Data obtained August 30-31 2011 from Health Ideas/PharmaNet database - Deaths of all causes recorded within 30 days of episode of methadone maintanence therapy - 100 Person years calculated as days of methadone maintanence treatment divided by 36,500 Fiscal Year Total Deaths in Methadone Maintenance Treatment Deaths per 100 Person Years 2001/2002 18 1.9 2002/2003 34 1.5 2003/2004 45 1.6 2004/2005 60 1.7 2005/2006 71 1.8 2006/2007 73 1.6 2007/2008 81 1.5 2008/2009 74 1.2 2009/2010 84 1.2 2010/2011 89 1.1 2011/2012 97 1.1 15

Figure 14 No. of deaths per 100 person years 16 6 5 4 3 2 1 0 Deaths by Any Cause per 100 Person Years During Methadone Maintenance by Health Authority, BC, 2001/2002 to 2011/2012 01 Interior 02 Fraser 04 Vancouver Island 05 Northern 03 Vancouver Coastal BC Total Notes: - Data obtained August 30-31 2011 from Health Ideas/PharmaNet database - Deaths of all causes recorded within 30 days of episode of methadone maintanence therapy - 100 Person years calculated as days of methadone maintanence treatment divided by 36,500 Patient Health Authority Fiscal Year Deaths per 100 Person Years 01 Interior 2001/2002 4.4 2002/2003 3.4 2003/2004 3 2004/2005 3 2005/2006 2.1 2006/2007 2.5 2007/2008 2 2008/2009 2.1 2009/2010 2.1 2010/2011 1.7 2011/2012 1.5 02 Fraser 2001/2002 1.5 2002/2003 1.1 2003/2004 0.9 2004/2005 1.4 2005/2006 1.8 2006/2007 1.3 2007/2008 1.4 2008/2009 0.8 2009/2010 1 2010/2011 0.6 2011/2012 0.8 2011 / 2012 Patient Health Authority Fiscal Year Deaths per 100 Person Years 03 Vancouver Coastal 2001/2002 1.2 2002/2003 1.2 2003/2004 1.7 2004/2005 1.9 2005/2006 1.8 2006/2007 1.9 2007/2008 1.9 2008/2009 1.5 2009/2010 1.4 2010/2011 1.6 2011/2012 1.2 04 Vancouver Island 2001/2002 2.3 2002/2003 1.5 2003/2004 1.6 2004/2005 1.3 2005/2006 1.5 2006/2007 0.9 2007/2008 0.6 2008/2009 1 2009/2010 0.7 2010/2011 1.1 2011/2012 1.4 05 Northern 2001/2002 5 2002/2003 4.5 2003/2004 3.5 2004/2005 2.6 2005/2006 2.2 2006/2007 2.5 2007/2008 4.2 2008/2009 1.8 2009/2010 1 2010/2011 0 2011/2012 0.8 BC Total 2001/2002 1.9 2002/2003 1.5 2003/2004 1.6 2004/2005 1.7 2005/2006 1.8 2006/2007 1.6 2007/2008 1.5 2008/2009 1.2 2009/2010 1.2 2010/2011 1.1 2011/2012 1.1