WHAT DO YOU WANT FROM A HOME VENTILATION SYSTEM? 8322_RS_HomeNIV_brochure_v14.ind1 1 4/7/06 12:57:35

WHAT DO YOU WANT FROM A HOME VENTILATION SYSTEM? 8322_RS_HomeNIV_brochure_v14.ind1 1 4/7/06 12:57:35

D I L E M M A DIFFERENT VENTILATORS DIFFERENT ALGORITHMS TO KNOW YOU VE CHANGED PATIENT LIVES?PATIENT?? NEEDS? TYPES OF PATHOLOGY DIFFERENT LEVELS OF PERFORMANCE Derek Parker. A 74 year old grandfather, Derek was finding it increasingly difficult to catch his breath after even mild exercise. Eventually he collapsed on his local golf course. Rushed to the hospital, Derek was diagnosed as suffering from acute pulmonary oedema You want your system of choice to be state-of-the-art of course, tested and clinically proven to offer optimum levels of efficiency, comfort, safety, versatility and prediction. You want facts and figures. But, perhaps above all, you want a Home Ventilation System you can trust to transform lives day to day; a system that behind the advanced technology and innovation has the power to put the quality, pure and simple, back into your patients lives. You want a Home Ventilation System from Respironics. We understand the pressure... choosing the right system is critical....an increasing number of machines have become available on the market, and the physician is often faced with the difficult task of choosing the optimal device for a given patient. Making the right choice is important, since performance and patient comfort vary among devices [...] These issues are key to the success of long-term home NIV, patientventilator dyssynchrony being one of the documented causes of patient intolerance to the technique 1 Our ultimate goal is to respond to you and your patients needs. To do this we have developed 5 major criteria, based on clinical data, that we believe describe the best solution. the efficiency of the ventilation provided the comfort of the patient in using ventilation the safety of the ventilation process the versatility of the unit in responding to change the prediction of future care needs 1. Performance characteristics of 10 Home Mechanical Ventilators in Pressure-Support Mode Battisti and co Chest 2005. 8322_RS_HomeNIV_brochure_v14.ind2-3 2-3 4/7/06 12:57:42

A N S W E R Digital Auto-TRAK Sensitivity AVAPS Cycle to EPAP crossover point IPAP Max IPAP Min EPAP Target Vt Estimated Patient Flow Trigger to IPAP Crossover Point Shape Signal Patient flow TO GIVE THEM PRECIOUS TIME TO HAVE TARGETED TECHNOLOGY... Late 80 s: BiPAP Technology and Auto-TRAK sensitivity introduction Respironics was the fiirst to introduce BiPAP technology with Auto-TRAK Sensitivity in response to clinical needs in the late 80 s, increasing the ability to ventilate patients who were previously treated via tracheotomy and to optimise patient-ventilator synchrony. Respironics groundbreaking innovation continued with the 2003 introduction of AVAPS based on the proven Auto-TRAK algorithm superiority to provide efficient and comfortable ventilation without compromise. Respironics technology works with the patient s natural rhythm to provide a gentle and comfortable breathing experience. 2001: Noninvasive Ventilator Triggering in Chronics Obstructive Pulmonary Disease AJRCCM, Stell and co 1997: Performance Characteristics of Bilevel pressure Ventilators Chest, Bunburaphong and co 2005: Performance Characteristics of 10 Home Mechanical Ventilators in Pressure Support Mode Chest, Battisti and co 2003: Respironics introduced AVAPS feature Digital Auto-TRAK Sensitivity Digital Auto-TRAK Sensitivity insures more natural and comfortable ventilation for patients by responding instantly to changing breathing patterns. Automatically adjusting to provide gentle encouragement on inhalation and expiration, no user adjustments are required. more efficiency - trigger sensitivity is optimised even in the case of changes in leaks more comfort - Auto-TRAK detects small effort to perfectly harmonise with patient rhythm more safety - leak compensations over 60LPM, patient ventilation (Ve, Vte and leaks) is estimated to alarm more versatility - trigger thresholds adjust to patient respiratory mechanics more prediction - triggers remain sensitive with changes in patient compliance and resistance AVAPS Average Volume Assured Pressure Support (AVAPS ) automatically adjusts the inspiratory pressure of breath being inhaled to ensure that the average tidal volume that has been set for an individual patient is reached guaranteeing the ventilation needed for effective therapy. more efficiency - average ventilation is guaranteed more comfort - pressure adjusts to patient needs more safety - pressure adapts to disease progression more versatility - pressure complies with disease requirement more prediction - IPAP progresses to ensure long term efficacy 8322_RS_HomeNIV_brochure_v14.ind4-5 4-5 4/7/06 12:57:46

BiPAP Harmony BiPAP Synchrony E F F I C I E N C Y C O M F O RT S A F E T Y Alarms: Patient Disconnection Apnoea Power cut Low battery Monitoring: Pressure Auto-TRAK Sensitivity & BiPAP Technology IPAP : 4 to 30 cmh 2 O EPAP : 4 to 25 cmh 2 O Optional integrated humidifier Size: 24 x 17 x 11 cm Weight : 1.8 Kg Alarms: Patient Disconnection Apnoea Power cut Low battery Low Tidal volume (AVAPS only) Low minute ventilation Monitoring: Pressure Estimated exhaled tidal volume Estimated exhaled minute ventilation Estimated leak Respiratory rate V E R S AT I L I T Y Battery back up: 7 hrs autonomy at 20/4 cmh 2 O of IPAP/EPAP Ventilation modes: CPAP, Continuous Pressure S, Spontaneous S/T, Spontaneous Timed Battery back up: 7 hrs autonomy at 20/4 cmh 2 O of IPAP/EPAP Ventilation modes: CPAP, Continuous Pressure S, Spontaneous S/T, Spontaneous Timed PS, Pressure Control T, Timed AVAPS, Average Volume Assured Pressure Support P R E D I C T I O N Encore Pro software, Encore Smartcard and Stardust II compatibility Analog Output Module for connection to most PSG systems, Direct Connection to Alice 5 PSG TO HAVE A RANGE OF VENTILATORS THAT FIT YOUR NEEDS TO SCREEN VENTILATION EFFICIENCY AND PATIENT COMPLIANCE BiPAP Harmony BiPAP Synchrony (featuring AVAPS ) Stardust II Encore Pro software The BiPAP Harmony is a reliable, high- The BiPAP Synchrony is a premium ventilation The Stardust II is a polygraph that links Every BiPAP system is fitted with an Encore performance ventilation unit that uses BiPAP system with comprehensive range of modes, to a BiPAP device, recording a patient s SmartCard that stores data gathered over technology and Auto-TRAK Algorithm to monitoring options and alarms to match respiratory effort and body position, oxygen the previous six months and generates reports reduce the effort of breathing, featuring: stringent treatment parameters, featuring: saturation, pulse rate and plots signals issued about how and when the system is being used. Digital Auto-TRAK technology optimises patient/ ventilator synchrony AVAPS technology guarantees the minimum ventilation needed for effective therapy by the BiPAP unit relating to the patient s flow, tidal volume, leaks and pressure. This allows clinicians to monitor patients compliance and identify when any adjustments Optional integrated humidifier for patient comfort Safety alarms for patient disconnection and apnoea Encore Pro and Stardust II compatibility for easy follow up at home Portable, compact and lightweight Digital Auto-TRAK technology optimises patient/ ventilator synchrony Complete range of patient ventilation alarms for increased safety Additional controlled ventilation modes for more severely ill patients Optional integrated humidifier for patient comfort Encore Pro and Stardust II compatibility for easy follow up at home Portable, compact and lightweight Flexible device that can be used alone as a polygraph or connected to Respironics CPAPs and bi-level devices Small and comfortable enough for home use Comprehensive measurement of pulse rate, SpO 2, thoraco-abdominal effort and BiPAP signals such as leaks, patient flow and tidal volume Automatic detection of abnormal respiratory events: obstructive apnoeas, central apnoeas, hypopnoeas, desaturations, bradycardia and tachycardia Generate synthesised reports in Word format to quickly assess ventilation efficacy and diagnose overlap syndromes are necessary for effective treatment. Easy to use, intuitive software Complete data base to store information on all your patients treated with CPAPs and bi-level devices Generates a patient homepage showing long-term and eight-day detailed trends on pressure, patient tidal volume, respiratory rate, percentage of triggered breaths, minute ventilation, leaks and alarms. Alerts can be scheduled when therapy reviews or patient visits are due 8322_RS_HomeNIV_brochure_v14.ind6-7 6-7 4/7/06 12:57:53

Clinical references E F F I C I E N C Y C O M F O RT S A F E T Y The ability of the ventilator to meet the patient s flow demand is another technical challenge. Flow demand mainly depends on the underlying pathophysiology. [ ] patient-ventilator dyssynchrony being one of the documented causes of patient intolerance to the technique. Performance Characteristics of 10 Home Mechanical Ventilators in Pressure-Support mode Battisti, Tassaux, Janssens, Michotte, Jaber, Jolliet Chest 2005 [ ] if ventilation is ineffective or uncomfortable the patient may reject it. In patients with chronic respiratory failure, non-invasive ventilation is performed during sleep and comfort is particularly important if sleep is not to be compromised and ventilation to be effective. for a patient with a high level of dependency upon the ventilator, a battery power source is mandatory in case of failure of the electricity supply, for movement outside the home or for transfers within the hospital. V E R S AT I L I T Y The management strategy is based on an individualized assessment of disease severity and response to various therapies. Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease GOLD scientific committee - NHLBI/WHO workshop summary - AJRCCM 2001 P R E D I C T I O N A respiratory therapist should visit the patient at home to reinforce proper use of the equipment and to make further adjustments to optimize fit and comfort, ideally weekly for the first few weeks. Ventilator Management for Neuromuscular Disease NS Hill, Respir Crit Car Med 2002 Respironics, Inc.: +1-724-387-4000 Respironics EAME: +33-1-47-52-30-00 Respironics Deutschland: +49-81-52-930-60 Respironics France: +33-2-51-89-60-00 Respironics Italy: +39-03-62-63-43-1 Respironics UK: +44-870-770-3434 Respironics Asia Pacific: +81-3-5280-9611 WWW.RESPIRONICS.COM Specifications subject to change without notice. CAUTION: US federal law restricts this device to sale by or on the order of a physician. Stardust, BiPAP, Synchrony, Harmony, Encore and Encore SmartCard are registered trademarks of Respironics, Inc. and its affiliates and Digital Auto-TRAK, AVAPS are trademarks of Respironics, Inc. and its affiliates. All rights reserved. 2006 Respironics, Inc. and its affiliates RIT.HMV.009.E bdc8322 05/06 8322_RS_HomeNIV_brochure_v14.ind8 8 4/7/06 12:57:53