PCORI Awarded Research Projects: Massachusetts

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PCORI Awarded s: Massachusetts January 2018 Total Number of s: 125 Total Awarded in State: $239,145,366 Title Organization Awarded Type Budget Promoting Autonomy and Improving Shared Decision Making for Older Tufts University $2,130,558 2017 Adults with Advanced Kidney Disease Comparative Effectiveness Research to Improve the Health of Sexual and Fenway Community Health $2,075,915 2017 Gender Minority (SGM) Patients through Cultural Competence and Skill Training of Community Health Center (CHC) Providers and Non-clinical Staff Center Reducing Health Disparities for Black Women in the Treatment of Insomnia Trustees of Boston $2,115,495 2017 University, BUMC Transgender Cohort Study of Gender Affirmation and HIV-related Health Boston Children's $1,977,993 2017 Predictive Analytics Pilot Study: Assessment of Heterogeneity of Treatment Tufts Medical Center, Inc. $546,780 2017 Effects in Two Major Clinical Trials Blacks Addressing Mental Health Concerns and Healing Through Comparative The Transformation Center $50,000 2017 Engagement in Effectiveness Research Healthy Aging in Place for Racial/Ethnic Minority Underserved Populations Community Engagement to Address Tuberculosis Infection in Persons Experiencing Homelessness Building a National Partnership to Identify the Mental Health Priorities of Young Adults with Intellectual and Developmental Disabilities (YA with I/DD) Promoting the Intersection of Research on Health Literacy and Patient- Centered Care Comparative Effectiveness of Early Integrated Telehealth Versus In-Person Palliative Care for Patients with Advanced Lung Cancer Causal Analyses of Nested Case-Control Studies for Comparative Effectiveness Research Comparing the Effectiveness of House Calls and Peer Mentorship to Reduce Racial Disparities in Live Donor Kidney Transplantation Study of Radiation Fractionation on Outcomes After Breast REConstruction (FABREC) Improving Oral Health for Vulnerable Populations - Individuals with IDD - Tier III Center for Community Health Education Research and Service, Inc. $50,000 2017 Engagement in $50,000 2017 Engagement in Boston University $50,000 2017 Engagement in Boston University Medical $249,964 2017 Engagement in Center $10,744,221 2017 Harvard T.H. Chan $1,030,646 2017 of Public Health Beth Israel Deaconess $1,789,919 2017 Medical Center Dana-Farber Cancer $2,690,013 2017 Tufts University $49,995 2017 Engagement in

After the ICU - Tier III Community Engagement to Improve Prevention and Treatment of Congenital Cytomegalovirus Infection - Tier II Engaging Cancer Survivors in the Community for Assessing Nutritional Needs and Barriers - Tier II Into the Light: Using Health Technology to Develop a Mother/Family Centered Peer Support Network - Tier II, Pulmonary and Critical Care Department Tufts University, Friedman of Nutrition Science and Policy $50,000 2017 Engagement in $24,998 2017 Engagement in $24,951 2017 Engagement in $24,994 2017 Engagement in Patient Engagement Efforts to Reduce (PEER) Diabetes Among Vietnamese Americans - Tier II Boston College $25,000 2017 Engagement in The Tulumbe - Tier II Multicultural AIDS Coalition $25,000 2017 Engagement in Unhealthy Substance Use Among Community-Based Older Adults: What is the Role of Home Health Aides? - Tier II Home Care Aide Foundation $24,981 2017 Engagement in Healing Families: Parental Involvement in the Treatment of Low-Income Teens Diagnosed with a Mood Disorder - Tier II Families for Depression Awareness $25,000 2017 Engagement in Summit and White Paper Report: Patient-Centered Outcomes and Age- Related Macular Degeneration The Angiogenesis Foundation $50,000 2017 Engagement in Establishing a Mechanism for Patient Centered Cancer Research at a Safety- Net Boston Medical Center $248,984 2017 Engagement in Improving Diabetes Prevention with Benefit-Based Tailored Treatment: Disseminating Patient-Centered Estimates of Benefit Tufts Medical Center $499,999 2017 Research Dissemination and Implementation Realization of a Standard of Care for Rare Diseases Using Patient-Engaged Boston Children's $704,428 2017 Phenotyping Evidence and the Individual Patient: Understanding Heterogeneous Treatment Effects for Patient-Centered Care Tufts Medical Center, Inc. $249,574 2016 Engagement in The MS Minority Research Engagement Partnership Network Accelerated Cure $249,743 2016 Engagement in How Well Do Clinical Prediction Models (CPMs) Validate? A Large-Scale Tufts Medical Center $996,916 2016 Evaluation of Cardiovascular Clinical Prediction Models Improving Outcomes for Low-Income Mothers with Depression: A Comparative Effectiveness Trial of Two Brief Interventions in the Patient- Centered Medical Home Boston Medical Center $2,097,588 2016

Smoker-to-Smoker (S2S) Peer Marketing and Messaging to Disseminate Tobacco Interventions Comparing Patient-Centered Outcomes for Adults and Children with Asthma in High-Deductible Health Plans with and without Preventive Drug Lists Engaging Patients and Stakeholders to Improve Cancer Outcomes in Navajo Nation Harvard Pilgrim Health Division of Global Health Equity, Brigham and Womenâ s $2,052,822 2016 $3,211,665 2016 $248,414 2016 Engagement in COPE-Navajo Nation Cancer Survivorship Conference Partners in Health $249,944 2016 Engagement in Boston BRI...DGE Center for Community Health Education Research and Service, Inc. $248,774 2016 Engagement in Unhealthy Substance Use Among Community-Based Older Adults: What is the role of home health aides? - Tier I Patient Engaged Efforts to Reduce (PEER) Diabetes among Asian Americans - Tier I Community Engagement to Improve Prevention and Treatment of Congenital Cytomegalovirus Infection - Tier I Engaging Cancer Survivors in the Community for Assessing Nutritional Needs and Barriers - Tier I Healing Families: Parental Involvement in the Treatment of Low-Income Teens Diagnosed with a Mood Disorder - Tier I Building Partnerships for Addressing HIV among African Immigrants - Tier I Shared Care: Patient-Centered Management after Hematopoietic Cell Transplantation Linking UDIs to Insurance Claims: A Pilot Demonstration Linking Randomized Clinical Trials and ClaiTRD Data for Enhancing Randomized and Non-Randomized Patient-Centered Outcomes Evidence Generation The Dabigatran, Apixaban, Rivaroxaban, Edoxaban, Warfarin Comparative Effectiveness Research Study (The DARE warfarin CER study) Comparing Three Treatments for Adults with Major Depression That Does Not Respond to First-Line Treatment Home Care Aide Foundation Vietnamese American Initiative for Development (Viet-AID) $14,916 2016 Engagement in $14,960 2016 Engagement in $15,000 2016 Engagement in Tufts University $14,974 2016 Engagement in Families for Depression $15,000 2016 Engagement in Awareness Multicultural AIDS $15,000 2016 Engagement in Coalition Dana-Farber Cancer $2,622,288 2016 $1,023,938 2016 $1,049,537 2016 $2,881,687 2016 $14,021,920 2016

Healthy Mind Healthy You Tailoring Patient Options for Medication Adherence Action Plans in Community Pharmacies - Tier II Improving Oral Health for Vulnerable Populations - Individuals with Intellectual and Developmental Disabilities - Tier II After The ICU: A Collaborative to Improve Critical Illness Survivorship - Tier II Improving Methods of Incorporating Racial/Ethnic Minority Patients' Treatment Preferences into Clinical Care Engaging Patients and Caregivers Managing Rare Diseases to Improve the Methods of Clinical Guideline Development Stratified Regression Models for Case-Only Studies $4,030,846 2016 Northeastern University $25,000 2016 Engagement in Tufts University $24,915 2016 Engagement in $24,461 2016 Engagement in, Pulmonary and Critical Care Department Cambridge Health Alliance $1,059,777 2016 RAND Corporation $1,015,931 2016 President & Fellows of $1,017,066 2016 Harvard College Patient Osteoarthritis Careplan to Inform Optimal Treatment $6,303,023 2016 Virtual Evidence-based Healthcare for Underserved Patients with Down $2,080,944 2016 Syndrome Healthy Hearts Healthy Minds: A PPRN Demonstration Pragmatic Trial $2,522,180 2016 Comparing Asthma Treatments: A Study Focusing on African-American, $13,942,838 2016 Hispanic, and Latino Adults Helping People with Serious Mental Illness Stop Smoking $10,080,737 2016 Comparing Ways to Help Patients Decide Whether to Have Surgery to $1,834,685 2015 Replace a Knee or Hip Acute Community Care to Avoid Unnecessary Emergency Department Visits $1,940,604 2015 Comparative Effectiveness of Metabolic and Bariatric Surgery using Patient $2,655,076 2015 Reported Outcome Measures (PROMs) Causal Inference Guidelines for Pragmatic Clinical Trials Harvard University $1,018,220 2015 of Public Health Enhancing Mental Health Care by Scientifically Matching Patients to $1,784,650 2015 Providersâ Strengths Massachusetts, Amherst 2016 Massachusetts PFAC Conference Health Care for All $97,035 2015 Engagement in

Understanding How Antibiotic Use Affects Childhood Obesity and Growth Harvard Pilgrim Health $4,553,788 2015 Connecting Community to Research: Building Skills to Partner in Research Boston Medical Center $200,000 2015 Engagement in MoodNetwork Phase II $1,802,202 2015 Research The Multiple Sclerosis Patient-Powered Research Network, iconquermsâ Accelerated Cure for Multiple Sclerosis $1,451,190 2015 Research Scalable Collaborative for a Learning Healthcare System (SCILHS) President & Fellows of Harvard College $9,135,742 2015 Research Health Literacy Annual Research Conference Boston Medical Center $249,821 2015 Engagement in Tailoring Patient Options for Medication Adherence Action Plans in Community Pharmacies Improving Oral Health for Vulnerable Populationsâ Individuals with Intellectual and Developmental Disabilities After The ICU: A Collaborative to Improve Critical Illness Survivorship Research Ethics in Patient-Centered Outcomes Research Integrating Online Weight Management with Primary Care Support: Patient- Centered Strategies for Addressing Overweight and Obesity in Primary Care Impact of High Deductible Health Plans on Patients with Bipolar Disorder ACCCES: A Collaboration to develop Capacity for Community Engaged research in Springfield Engaging Peers in Comparative Effectiveness Research Franciscan Helps Families Connect (FHFC) Privacy-Preserving Analytic and Data-Sharing Methods for Clinical and Patient-Powered Data Networks Improving Communication between Patients and Cancer Doctors Using Patient Feedback on Real Conversations Massachusetts $15,000 2015 Engagement in Pharmacists Association Tufts University $14,958 2015 Engagement in $10,672 2015 Engagement in, Pulmonary and Critical Care Department $1,423,719 2015 $2,006,429 2015 Harvard Pilgrim Health $1,465,671 2015 Baystate Medical Center $249,437 2014 Engagement in Boston VA Research $250,000 2014 Engagement in, Inc. Franciscan for $250,000 2014 Engagement in Children Harvard Pilgrim Health $1,420,274 2014 Dana-Farber Cancer $1,776,243 2014 ^

Optimization of Home Oxygen Weaning in Premature Infants Preventive Sexual Health Screening Among Female-to-Male Transgender Adult Patients Comparing the Benefits and Harms of Five Different Medicines for Long-Term Treatment of Blood Clots Improving Measurement of Health Care Transitions through Key Stakeholders' Eyes Preventing Serious Falls Among Older Adults: A Supported by PCORI and the National on Aging of the National s of Healthâ The STRIDE Study PCORnet Coordinating Center Phase I (Harvard Pilgrim Health Care) Do Weight Management Programs Involving Health Coaches Improve Body Mass Index and Parent Empowerment for Children with Obesity or Who Are Overweight? Optimizing Patient Engagement in a Novel Pain Management Initiative (OPEN) Persons with Disabilities Generating Quality Metrics to Inform Integrated Care Mobile Application for Improving Symptoms and Adherence to Oral Chemotherapy in Patients with Cancer A Multiple Sclerosis Patient-Powered Research Network ^ Fenway Community Health Center Worcester Harvard Medical ; Yale Medical ; UCLA Medical Harvard Pilgrim Health $1,180,635 2014 $956,186 2014 $1,051,488 2014 $1,100,731 2014 $29,999,787 2014 $13,171,034 2013 Research $2,153,815 2013 Inflexxion, Inc. $2,080,941 2013 Accelerated Cure for Multiple Sclerosis $2,019,733 2013 $1,898,123 2013 $977,965 2013 Research ALD Connect ALD Connect, Inc. $675,483 2013 Research Sleep Apnea Patient Centered Outcomes Network (SAPCON) Mood Patient-Powered Research Network Effectiveness of DECIDE in Patient-Provider Communication, Therapeutic Alliance & Care Continuation ^ (The General Corp.) ^ $1,002,649 2013 Research $930,011 2013 Research $2,165,211 2013

Shared Decision Making and Renal Supportive Care Baystate Medical Center $2,094,827 2013 Bringing I-PASS to the Bedside: A Communication Bundle to Improve Patient Boston Children's $2,098,500 2013 Safety and Experience Benchmarking the Comparative Effectiveness of Diabetes Treatments Using Harvard University ( $2,025,244 2013 Patient-Reported Outcomes and Socio-Demographic Factors of Public Health) Heart Health 4 Moms: Engaging Women with a History of Preeclampsia to $2,234,891 2013 Reduce their Risk for Cardiovascular Disease Scalable Collaborative for a Learning Healthcare System (SCILHS) Harvard University Medical $6,624,810 2013 Research Eliminating Patient-Identified Socio-Legal Barriers to Cancer Care Boston Medical Center $1,678,273 2013 Patient-Centered Approaches to Collect Sexual Orientation/Gender Identity Brigham and Womenâ s $1,549,883 2013 Information in the Emergency Department ^ Which Treatments for Uterine Fibroids Have the Best Results? Outcome Sciences, Inc. $1,147,733 2013 Impact of Radiation Therapy on Breast Conservation in DCIS Dana-Farber Cancer $1,203,120 2013 Cervical Spondylotic Myelopathy Surgical Trial (CSM-S Trial) Lahey Clinic $2,079,575 2013 Improving Informed Consent for Palliative Chemotherapy: Development of a Regimen-Specific Multi-Media Informed Consent Library to Promote Patient- Centered Decision Making about Treatment of Advanced Gastrointestinal Cancers Causal Inference for Effectiveness Research in Using Secondary Data Methods for Variable Selection and Treatment Effect Estimation in Nonrandomized Studies with Few Outcome Events and Many Confounders Improving the Use of Patient Registries for Comparative Effectiveness Integrating Causal Inference, Evidence Synthesis, and Research Prioritization Methods A Method for Patient-Centered Enrollment in Comparative Effectiveness Trials: Mathematical Equipoise Integrative Medicine Group Visits: A Patient-Centered Approach to Reducing Chronic Pain and Depression in a Disparate Urban Population Evaluating the Navajo Community Outreach and Patient Empowerment (COPE) Program Comparing the Predicted Benefits and Harms of Using Adult versus Child Guidelines for Lipid Testing and Treatment in 17- to 21-Year-Olds Dana-Farber Cancer $1,063,122 2013 $1,102,522 2013 $997,989 2013 $888,534 2013 Tufts Medical Center $1,095,505 2013 Tufts Medical Center $1,123,588 2013 Boston Medical Center $1,929,563 2013 $1,937,699 2013 Tufts Medical Center, Inc. $1,045,998 2012

Pilot : Creating a Decision-Support Computer Program to Help Cancer Dana-Farber Cancer $662,145 2012 Patients Understand and Manage Their Symptoms Pilot : Testing Computer Programs That Help People Stop Smoking $619,313 2012 Pilot : Figuring Out Which Patients Are Likely to Return to the Boston University $687,978 2012 of Medicine/ Boston Medical Center Pilot : Predicting Who Will Respond Best to Medical Treatments Tufts Medical Center Inc. $691,048 2012 Pilot : Engaging Patients, Doctors, and Healthcare Experts in Creating $693,087 2012 Guidelines for Cancer Screening Pilot : Figuring Out Why Some Patients Do Not Fill Their Blood $518,904 2012 Pressure Prescriptions Pilot : Helping People Understand and Use Cancer Screening Recommendations Relative Patient Benefits of a -PCMH Collaboration within an ACO to Improve Care Transitions Relapsed Childhood Neuroblastoma as a Model for Parental End-of-Life Decision-Making, Inc. Dana-Farber Cancer $686,611 2012 $1,957,492 2012 $985,992 2012