Table Of Content. Invasive Bacterial Infections Surveillance in the European Union... 2 Summary... 3 Coordinator, Leader contact and partners...

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Table Of Content Invasive Bacterial Infections Surveillance in the European Union... 2 Summary... 3 Coordinator, Leader contact and partners... 5 National School of Public Health... 5 National Institute of Public Health... 5 Irish Meningococcal & Meningitis Reference Laboratory... 5 Instituto de Salud Carlos III... 5 National Institute of Public Health and the Environment (RIVM)... 5 Direction de la Santé... 5 Centre hospitalier universitaire de Toulouse... 5 Norwegian Institute of Public Health... 5 State Agency Public Health Agency... 5 National Health Laboratory... 5 National Public Health Institute (KTL)... 5 National Institute of Health... 5 Scientific Institute of Public Health... 5 Institute of Laboratory Medicine... 5 University of Wurzburg... 5 National Institute of Hygiene... 5 Austrian Agency for Health and Food Protection (AGES)... 5 Johan Be'la National Centre for Epidemiology... 5 National Reference Laboratory for Pathogenic Neisseria... 5 Department of Public Health... 5 National Public Health Institute of Slovak Republic... 5 Directorate of Health... 5 Health Protection Inspectorate... 5 Robert Koch Institut... 5 Institut Jules Bordet Laboratoire... 5 FM for Health and Women... 5 Istituto Superiore di Sannita... 5 Johannes Gutenberg Universität... 5 Institut Pasteur... 5 Institute of Public Health of the Republic of Slovenia... 5 Statens Serum Institute... 5 Narodowy Instytut Zdrowia Publicznego (National Institute of Public Health)... 5 Institut de Veille Sanitaire... 5 Academic Medical Centre... 5 Swedish Institute for Infectious Disease Control... 5 National Disease Surveillance Unit Sir Patrick Dunne's Hospital... 5 -Aghia Sophia- Children's Hospital... 5 Direcção-Geral da Saúde... 5 Outputs... 12 Original Full Information (Dec 2008)... 12 Page 1/12

Invasive Bacterial Infections Surveillance in the European Union JA2015 - GPSD [705038] START DATE: 02/10/2003 END DATE: 02/10/2006 DURATION: 36 month(s) CURRENT STATUS: Finalised PROGRAMME TITLE: First Programme of Community action in the field of public health (2003-2008) PROGRAMME PRIORITY: - CALL: Health Threats (Ht 2003) TOPIC: Enhancing the capability of responding rapidly and in a co-ordinated fashion to health threats EC CONTRIBUTION: 665877 EUR KEYWORDS: PORTFOLIO: Communicable diseases Page 2/12

SUMMARY General objectives The general objective of the project was to improve the epidemiological information on invasive meningococcal and Haemophilus influenzae disease within the European Union and the laboratory capacity to accurately characterise the isolates of H. influenzae and Neisseria meningitidis. In addition, the project was also aiming at evaluating the impact of vaccination with conjugate vaccines on the epidemiology of H. influenzae and N. meningitidis, and compare the impact of vaccination with conjugate vaccines produced by different manufacturers and according to different schedules. Finally, EU-IBIS was also intended to form a focus for wider collaboration with non European Union countries and candidate European Union countries. Strategic relevance and contribution to the public health programme The development of web-based system for rapid exchange of information on meningococcal infection had an international importance. EU-IBIS was intended to develop a web-based notice board for rapid dissemination of information across the Community Network (epidemiological surveillance structures) of Decision 2119/98/EC and the EU-IBIS network and hence EU, allowing appropriate action to be taken with contacts of travel-associated cases. Methods and means A separate disease surveillance network has been established for each of H. influenzae and N. meningitidis, and these run independently. Standardised case definitions laid down by Community legislation were used. Where surveillance is performed using other definitions, datasets were re-coded to provide comparable data for all participating countries. The descriptive epidemiology was analysed using standard statistical packages on the minimum data set provided for each infection (including age, sex, date of onset, method of confirmation, site of identification, grouping, typing and subtyping results as appropriate). Analysis of age-specific incidence rates, seasonality, temporal trends and diversity of H. influenzae and N.meningitidis infections were examined. In countries with vaccination programmes, coverage data was also requested and comparison of rates of infection in both vaccinated and unvaccinated cohorts was interpreted in conjunction with coverage, schedule and vaccine used, implementation and method of introduction. Where a need was seen, sentinel reference laboratories were asked to report cases of an emergent strain of H. influenzae or N. meningitidis, and this information was sent to the Community Network (epidemiological surveillance structures) of Decision 2119/98 EC and shared on the Eurosurveillance bulletin A Web enabled database was developed and an alert page was warning of any trends in participant countries that may have implications for other member states or for countries that may access the Page 3/12

site. Expected outcomes period EU-IBIS / H. influenzae and Meningococci network had to provide annual reports to network participants and the Community Network (Decision 2119/98/EC) on the epidemiological data analyses, reports to network participants on EQAS analyses, presentation of surveillance network results at EU-IBIS network meetings and relevant scientific conferences. EU-IBIS was also intended to publish its results in peer review journals, in Eurosurveillance and on Internet. In addition, for EU-IBIS/ Meningococci network, the project developed a Web-enabled database in order to allow the rapid transfer of data on imported and emergent strains of N. meningitides. EU-IBIS was also inteneded to report on progress towards harmonisation of policy on control of N. meningitidis and on the actions needed to achieve it. Page 4/12

COORDINATOR, LEADER CONTACT AND PARTNERS COORDINATOR Health Protection Agency - Communicable Disease Surveillance Centre (Health Protection Agency - Communicable Disease Surveillance Centre) 61 Colindale Avenue NW9 5EQ London United Kingdom Project leader contact Name: RAMSAY Mary Email: Mary.ramsay@hpa.org.uk Phone: +44.208327.7085 PARTNERS National School of Public Health Country: Greece National Institute of Public Health Country: Czech Republic Irish Meningococcal & Meningitis Reference Laboratory Country: Ireland Page 5/12

Instituto de Salud Carlos III Country: Spain National Institute of Public Health and the Environment (RIVM) Country: Netherlands Direction de la Santé Country: Luxembourg Centre hospitalier universitaire de Toulouse Country: France Norwegian Institute of Public Health Country: Norway State Agency Public Health Agency Country: Latvia Page 6/12

National Health Laboratory Country: Luxembourg National Public Health Institute (KTL) Country: Finland National Institute of Health Country: Portugal Scientific Institute of Public Health Country: Belgium Institute of Laboratory Medicine Country: Iceland University of Wurzburg Country: Germany Page 7/12

National Institute of Hygiene Country: Poland Austrian Agency for Health and Food Protection (AGES) Country: Austria Johan Be'la National Centre for Epidemiology Country: Hungary National Reference Laboratory for Pathogenic Neisseria Country: Sweden Department of Public Health Country: Malta National Public Health Institute of Slovak Republic Country: Slovakia Directorate of Health Page 8/12

Country: Iceland Health Protection Inspectorate Country: Estonia Robert Koch Institut Country: Germany Institut Jules Bordet Laboratoire Country: Belgium FM for Health and Women Country: Austria Istituto Superiore di Sannita Country: Italy Johannes Gutenberg Universität Page 9/12

Country: Germany Institut Pasteur Country: France Institute of Public Health of the Republic of Slovenia Country: Slovenia Statens Serum Institute Country: Denmark Narodowy Instytut Zdrowia Publicznego (National Institute of Public Health) Country: Poland Institut de Veille Sanitaire Country: France Academic Medical Centre Page 10/12

Country: Netherlands Swedish Institute for Infectious Disease Control Country: Sweden National Disease Surveillance Unit Sir Patrick Dunne's Hospital Country: Ireland -Aghia Sophia- Children's Hospital Country: Greece Direcção-Geral da Saúde Country: Portugal Page 11/12

Powered by TCPDF (www.tcpdf.org) OUTPUTS Original Full Information (Dec 2008) Health Protection Agency - Communicable Disease Surveillance Centre Invasive Bacterial Infections Surveillance in the European Union (EU-IBIS - ) Published on: 02/10/2003 http://azorina.cc.cec.eu.int:8082/publications/2003202/2003202.pdf Page 12/12