IROC Head and Neck Phantom. Guidelines for Planning and Irradiating the IROC IMRT Phantom. Revised MARCH 2014

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IROC Head and Neck Phantom Guidelines for Planning and Irradiating the IROC IMRT Phantom. Revised MARCH 2014 The study groups are requesting that each institution keep the phantom for a period of time less than 2 weeks. During this two-week period, the institution will image, plan, and treat the phantom and return it to the IROC HOUSTON. Thank you for your cooperation. This phantom has been designed and constructed by the Imaging and Radiation Oncology Core Houston (IROC). The phantom contains at 8 locations and perpendicular sheets of film. Four are located in the primary PTV, and two each in the secondary PTV and in the organ at risk (spinal cord). If you have any questions, please contact the appropriate person. IROC IROC Nadia Hernandez (713)-745-8989 Nhernand@mdanderson.org Andrea Molineu (713) 745-8989 amolineu@mdanderson.org DOSIMETRY INFORMATION TO BE SUBMITTED: The following information is to be submitted to IROC HOUSTON (include in the shipping box): Original hard-copy isodose distributions in the axial and sagittal planes through the target volume. Please ensure that each plane fills an entire page and that a scale is printed on the page. The axial plane is essentially the central plane and contains the axial film. The film in the sagittal plane is easily seen in the CT scans. A completed IROC Head and Neck Phantom-Institution Information form. A copy of results of all film and ion chamber QA measurements. The following information is to be submitted to IROC Houston (results will not be analyzed until the digital treatment plan is received: Please follow the login URL: https://mdandersonorg.sharefile.com Login information: Username: trangnguyen@mdanderson.org Password: Phantom8989 Click on folder named IROC IMRT head and neck phantom folder; select the Add Folder tab on the top right hand side of the screen. In the folder name box, enter your institution name, city and state, then click Create Folder. Select the folder that you have created, then select Upload Files tab on the right hand side. In the Details box please type in phantom type, irradiation date, and physicist name. Follow the instruction and upload your files. Select Send email notification box when done. Lastly Click Upload Files. The files to export to the IROC are the digital data for your IMRT head and neck phantom irradiation in DICOM format, and include all CT slices, 3D composite dose file, structure file and plan file. Please log out once you finish and inform IROC by email, Nhernand@mdanderson.org. The Phantom should be imaged, planned, and irradiated as if it were an actual protocol patient, incorporating all of your customary quality assurance checks. DOSE PRESCRIPTION: The doses to be delivered to the phantom are a factor of 10 less than the protocol dose specifications, namely: Primary PTV. 6.6 Gy to at least 95% of the PTV and < 1% of the PTV receives < 93% of the prescribed dose. Secondary PTV (Node or Salivary gland): 5.4 Gy to at least 95% of the PTV and < 1% of the PTV receives < 93% of the prescribed dose. Organ at risk: < 4.5 Gy, maximum dose. Normal tissue: 110% of the prescribed dose (6.6 Gy). 1

IRRADIATING THE PHANTOM Material included in box: Head Phantom, with 4 capsules taped to the ears. Phantom insert Envelope with background film (hidden from your view; please don t try to find it) Pillbox to accept from phantom ears. Mailing label to return case to IROC at IROC cost. Traditional IROC block and irradiation table. (Please irradiate this at the time you irradiate the phantom.) Adjust the head so that the axial film is perpendicular to the table. The adjustment screws in the back of the phantom base should make the phantom adaptable to most head holders. Procedures: 1. Fill with water: 1.1. Remove both PVC plugs from the base of the phantom. 1.2. Fill slowly with water. You may need to jiggle the head to release air trapped in the nose etc. 1.3. Remove hose and replace PVC plugs. 2. Allow the phantom to sit with water in it for 20 min. to check for leaks. 3. Look in the insert space and check for water leakage. If you find any water call IROC Houston. If not, proceed to the next step. 4. This phantom has only one insert. The same insert is used for both imaging and for treatment. To position the insert, align the two red arrows. This places the "organ at risk" posterior to the primary target, and the secondary target to the right (phantom #1, 7-15) or left (phantom 2-5) of the primary target. 5. Make sure that there are one capsules taped into each ear. If they have come out, please tape them back in. They will remain in for the imaging process, then be removed so as to determine background for the Therapy in the insert. 6. CT Scan the phantom as you would a patient. You may wish to scan with 1.5 mm slices especially near the center to better identify the capsules. Rotate the adjustment screws to support and position the phantom. 7. REMOVE THE CAPSULES FROM THE EARS. Place in a pillbox labeled ear. 8. Remove insert from head during planning process. Store insert in a dry place where it will not be irradiated. 9. Segment the phantom images contouring the skin, primary and secondary planning target volumes (PTVs) and the organ at risk (OAR) analog (posterior to the primary target volume crescent) and all 8 volumes. are in the locations shown in the diagram superior and inferior to the axial film. Please use the following names for your contours: PTV_66 for the 1 PTV PTV_54 for the 2 PTV CORD for the OAR 66_Sant_ and 66_Iant_ for the superior and inferior anterior s in the 1 PTV 66_Spost_ and 66_Ipost_ for the superior and inferior posterior s in the 1 PTV SCORD_ and ICORD_ for the superior and inferior s in the OAR S54_ and I54_ for the superior and inferior s in the 2 PTV The dimensions of the volume are approximately 10 mm long by 2 mm diameter The outside dimensions of the capsules are 15 mm long by 4 mm diameter, the axis lies in a sagittal plane. (Both the capsules and the should be visible on CT image) 10. Plan the treatment as specified in the DOSE PRESCRIPTION above. 11. Perform your customary QA of the IMRT plan prior to irradiating the phantom. 12. Irradiate the IROC block according to the instructions provided. 13. Look in the insert space and check for water leakage. If you find any water call the IROC. If not, load the insert into the head. 14. Treat the phantom with the developed plan as you would an actual patient. Try to avoid positioning the axial film at the abuttment of adjacent MLC leaves or adjacent arcs. Abutting fields or leaves on the film may increase the uncertainty of the measurement. 15. Drain the water. 16. Remove the insert and place it in the box. 17. Please verify that there is no water in the insert space. If you find any water call IROC Houston. 18. Screw in the two water plugs. Leave the plugs loose. 19. Put the empty phantom in the box. 20. Make sure that the "ear " pillbox is on the box. 21. Include the dosimetry data discussed above. Complete the attached forms. Be sure to include the scale used on the images coming form your TPS. Isodose lines should include at least the following: 6.6, 5.4, 5, 4.5, 4, 3.5 Gy. 22. Return the complete package to IROC Houston. 2

IROC Head and Neck Phantom- Institution Information Institution: Address: Person performing irradiation: Physicist to receive report: Oncologist to receive report: Person to call in case of questions: Phone Number: Fax Number: Email address: Treatment Unit: Manufacturer: Model: In-house specification: Serial number: Photon Energy Nom (MV) IR (TMR 20/TMR 10): %dd(10) x FFF beam SRS beam Intensity Modulation Device: MIMIC Multileaf Collimator Solid Attenuator Modulation IMRT Technique: Segmental (step and shoot) MLC Dynamic MLC Tomotherapy VMAT Rapid Arc Other: 3

Please enclose original copies of your treatment plans. Include the slices where the films are and scaling factors. FTP the digital treatment plan. Treatment Planning System: Manufacturer: Model: Algorithm Software: Version Number: Treatment of Phantom: Date of Irradiation: Dose specified is to: Muscle Water Indicate the dose delivered to the as determined by your treatment planning computer Mean Dose(Gy) Min Dose(Gy) Max Dose(Gy) Ant 1 PTV superior(66 Sant) Ant 1 PTV inferior (66 I ant) Post 1 PTV superior (66 S post) Post 1 PTV inferior (66 I post) 2 PTV superior (S54) 2 PTV inferior (I54) Organ at risk superior (S cord) Organ at risk inferior (I cord) Results of IMRT QA (please attach copies of measurement data): Did you adjust the MU based on these results? If so, how much? Did you irradiate the phantom in service or clinical mode? Did you use your record and verify system? Attach copies of the treatment plan including a plan in the axial and sagittal film planes Comments: For Office Use Only Batch 11 EBT2 FILM LOT # 07301301 Phantom ID # Code Date Sent Date Rec'd 4

This is a cross sectional view of the insert. The superior and inferior to the axial film. Anterior Primary PTV Sagittal Film Plane Posterior Right Anterior Left Secondary PTV Organ at risk Posterior Axial Film Plane Note: You need to deliver 6.6 Gy to the 1 o PTV (in 1 or more fraction). Total dose to the 1 0 PTV 6.6 Gy Thanks Phantom team @ IROC HOUSTON! 5