Reduction in salt consumption in Europe: a preventive and economic imperative Francesco P Cappuccio MD MSc DSc FRCP FFPH FBHS FAHA

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Reduction in salt consumption in Europe: a preventive and economic imperative Francesco P Cappuccio MD MSc DSc FRCP FFPH FBHS FAHA Professor of Cardiovascular Medicine & Epidemiology Head, WHO Collaborating Centre University of Warwick, Coventry, UK Disclosures: Technical Advisor to the World Health Organization, the Pan American Health Organization, Member of C.A.S.H., W.A.S.H., UK Health Forum and Trustee of the Student Heart Health Trust all unpaid.

Why blood pressure and salt intake UN-WHO priorities? UN-WHO: World Health Assembly, 2010

Proportion of deaths attributable to leading risk factors in Europe (2000) ~2.5m 3

Salt intake is at least twice the maximum recommended level in most countries of the world 8.5M deaths in LMICs could be prevented over 10 years if sodium intake were reduced by 15% Powles J et al. BMJ Open 2013;3:e003733

Population salt reduction for the prevention of cardiovascular disease A reduction in salt intake reduces BP A reduction of 5g per day may reduce strokes by as much as 23% (i.e. 1.25M deaths worldwide) Evidence of benefits as low as 3g salt per day Effective in both genders, any age, ethnic group, high, medium and lowincome countries Population salt reduction programs are both feasible and effective (preventive imperative) Salt reduction programs are cost-saving (US: $6-12 saved for every $ spent; UK: 40m a year saved for 3g/d population salt reduction)(economic imperative) Policies are powerful, rapid, equitable, cost-saving

Communication Reformulation Monitoring Research Components of a strategy to reduce population salt intake Public Awareness Campaigns Consumers Food industry Decision makers Media Health Professionals Setting Targets Reformulation Benchmarking food categories Labelling Industry Engagement Motivation Costs & Benefits Consumer awareness Wider support Corporate responsibility Voluntary vs Regulatory Population salt intake Urinary sodium Dietary surveys Reformulation progress Salt content of foods (databanks; self-reporting by industry; market surveys) Effectiveness of communication Measuring awareness of campaigns Measuring attitudes and behaviour changes Epidemiology Nutrition Public Health Food technology Behavioural Evaluation Policy Cappuccio FP et al. BMJ 2010;343:402-5

Inequalities in salt reduction policies in WHO Region for Europe IHDI=Inequality-adjusted Human Development Index Rodriguez-Fernandez R et al. Public Health Nutr 2014;17:1894-1904

Salt intake reduced by 1.4 g/day in the UK between 2000 and 2011 NDNS 2000-1 NDNS 2008-11 9.5 g/day 8.1 g/day at least 9,000 deaths averted

Social inequalities in salt intake in Britain before and after a national salt reduction programme NDNS 2000-1 (n=2,105) All whites Dietary Na: 7-day food records Urinary Na: 24h urine collections BMJ Open 2013; 3: e002246 NDNS 2008-11 (n=1,027) All whites Dietary Na: 4-day food diary Na reduction: 366mg (0.9g salt) from food sources (non-discretionary) BMJ Open 2014; 4: e005683

Policy options: health equity and effectiveness Policy options for population reduction in salt intake Set in Marmot Reviews (UK and WHO, 2010) Policy interventions: Structural ( downstream affecting food environment) e.g. legislative and fiscal changes, mandatory reformulation effective and reducing inequalities Agentic ( upstream reliance on individual choice) e.g. social marketing, awareness, health promotion, behavioural politically more likely but fewer benefits and potentially widen inequalities. Cappuccio FP et al. BMJ 2010;343:402-5

Policy forecast for England up to 2025: health equity and effectiveness expressed as relative socio-economic differentials Intervention Salt intake Systolic BP Premature CHD postponed Life years gained Mandatory reformulation 1.14 (1.08-1.21) 1.14 (1.05-1.23) 4.41 (3.58-5.44) 2.75 (2.31-3.28) Voluntary reformulation 0.90 (0.21-1.78) 0.90 (0.22-1.76) 3.51 (0.75-9.26) 2.19 (0.56-4.73) Social marketing 0.45 (0.15-0.89) 0.46 (0.15-0.90) 1.42 (0.53-2.92) 1.08 (0.43-2.13) Nutrition labelling 0.46 (0.08-1.12) 0.47 (0.09-1.12) 1.48 (0.39-3.82) 1.11 (0.31-2.69) Gillespie DOS et al. PLoS ONE 2015; 10: e0127927

Conclusions Salt intake is too high. Cause of avoidable ill-health and associated healthcare and social costs. A moderate reduction is feasible, achievable and cost-effective (saving). Different economies have different sources of dietary salt (from processed food and industrial food production to social and cultural behaviour in salt use). Strategies include public awareness campaigns, comprehensive reformulation programmes and surveillance of salt intake and food salt content. The food manufacturing and retail industries have the capability and the responsibility to contribute substantially to these aims given their outreach. Voluntary and effective food reformulation has been the preferred choice. Mandatory actions and state-led market interventions are available and being used (e.g. South Africa for mandatory reformulation, Belgium for salt in bread). Policies should be set to narrow the social inequalities in salt consumption.