Monthly Vaccine Preventable Disease and Immunization Update Published: March 10, 2015 Immunization and Vaccine Development (IVD) SEARO Protecting People from Vaccine Preventable Diseases
Last wild poliovirus case by type, SEAR WPV Type 2 District: Aligarh State: Uttar Pradesh (India) Date of onset: 24-Oct-1999 WPV Type 3 District: Pakur State: Jharkhand (India) Date of onset: 22-Oct-2010 WPV Type 1 District: Howrah State: West Bengal (India) Date of onset: 13-Jan-2011 Last wild poliovirus case by country Country Year Bangladesh 2006 Bhutan 1986 DPR Korea 1996 India 2011 Indonesia 2006 Maldives 1994 Myanmar 2007 Nepal 2010 Sri Lanka 1993 Thailand 1997 Timor-Leste 1995 *Dots are randomly placed within blocks (Sub-districts)
Non-Polio AFP Rate Non-polio AFP Rate* SEAR, 2010 2014 6 and above 5.5 5 4.5 4 3.5 3 2.5 2 1.5 1 0.5 13.49 13.94 12.65 12.50 12.07 6.12 ~~~~~~~~ SEAR Minimum Target 0 BAN BHU DPRK IND INO MAV MMR NEP SRL THA TLS 2010 2011 2012 2013 2014 * Number of discarded AFP cases per 100,000 children under 15 years of age 3
Percent Percent Adequate Stool Specimen Collection* SEAR, 2010-2014 Minimum Target 100 80 60 40 20 0 BAN BHU DPRK IND INO MAV MMR NEP SRL THA TLS 2010 2011 2012 2013 2014 *Percentage with 2 specimens 24 hours apart and within 14 days of paralysis onset. 4
N=847 N=909 N=862 Percent of Non-Polio AFP Cases Under Immunized for OPV (6 Months to 5 Yrs), SEAR, 2010-2014 N=794 N=832 N=33081 N=35175 N=33691 N=30571 N=28206 N=762 N=931 N=987 N=964 N=827 N=137 N=170 N=164 N=145 N=157 N=281 N=277 N=303 N=291 N=236 N=98 N=103 N=100 N=76 N=77 5
Non-polio AFP Rate* Surveillance Indicators by District India, 2014 Percent Adequate Stool Specimen Collection ** Non-Polio AFP Rate < 1 1 1.99 >2 No Non-Polio AFP Case Adequate Stool Specimen Collection < 60% 60% 79% > 80% No AFP Case * Number of discarded AFP cases per 100,000 children under 15 years of age ** Percentage with 2 specimens 24 hours apart and within 14 days of paralysis onset. Note: Some AFP cases may still be pending final classification. Total AFP Cases = 54821 Non-Polio AFP Rate =12.07 Adequate Stool specimen = 86% Districts reporting AFP cases= 636 (95%) 6
Non-polio AFP Cases by Month of Onset India, 2010-2014 Month 2010 2011 2012 2013 2014 Jan 3654 4241 4599 4132 4111 Feb 3181 3538 4113 3644 3653 Mar 3834 3983 4170 3885 3787 Apr 4123 3926 4262 3864 3618 May 4511 4462 5001 4007 4039 Jun 4674 4978 4988 4622 4640 Jul 5541 5692 5452 5385 5044 Aug 6566 6582 7119 5555 5702 Sep 6231 6852 7386 5590 5398 Oct 5081 5800 5282 4888 4384 Nov 4321 5400 4455 4777 4298 Dec 3830 5024 4063 4245 3483 Total 55547 60478 60890 54594 52157 7
Surveillance Indicators by District Nepal, 2014 Non-polio AFP Rate* Percent Adequate Stool Specimen Collection ** Non-Polio AFP Rate < 1 1 1.99 >2 No Non-Polio AFP Case Total AFP Cases = 486 Non-Polio AFP Rate = 4.82 Adequate Stool specimen = 95% Districts reporting AFP cases= 70 (93%) Adequate Stool Specimen Collection < 60% 60% 79% > 80% No AFP Case * Number of discarded AFP cases per 100,000 children under 15 years of age ** Percentage with 2 specimens 24 hours apart and within 14 days of paralysis onset. Note: Some AFP cases may still be pending final classification. 8
Non-polio AFP Cases by Month of Onset Month 2010 2011 2012 2013 2014 Nepal, 2010-2014 Jan 36 43 50 32 50 Feb 39 21 51 41 48 Mar 37 42 47 61 40 Apr 59 46 51 56 31 May 56 49 61 49 41 Jun 47 44 69 57 41 Jul 65 59 70 65 47 Aug 86 64 92 63 38 Sep 68 63 69 47 40 Oct 46 43 37 30 36 Nov 30 48 22 37 38 Dec 29 46 21 38 33 Total 598 568 640 576 483 9
Non-polio AFP Rate* Surveillance Indicators by Province Myanmar, 2014 Percent Adequate Stool Specimen Collection ** Non-Polio AFP Rate < 1 1 1.99 >2 No Non-Polio AFP Case Adequate Stool Specimen Collection < 60% 60% 79% > 80% No AFP Case * Number of discarded AFP cases per 100,000 children under 15 years of age. ** Percentage with 2 specimens 24 hours apart and within 14 days of paralysis onset. Note: Some AFP cases may still be pending final classification. Total AFP Cases = 390 Non-Polio AFP Rate =1.78 Adequate Stool specimen = 96% Provinces reporting AFP cases= 18 (100%) 10
Non-polio AFP Cases by Month of Onset Myanmar, 2010-2014 Month 2010 2011 2012 2013 2014 Jan 30 27 18 32 41 Feb 21 29 9 13 24 Mar 24 24 11 16 18 Apr 15 21 22 20 22 May 13 33 35 18 38 Jun 23 36 42 27 38 Jul 37 41 44 34 39 Aug 55 39 58 36 46 Sep 64 53 96 27 42 Oct 49 52 64 49 25 Nov 40 38 33 63 23 Dec 42 25 24 69 25 Total 413 418 456 404 381 11
Surveillance Indicators by District Bangladesh, 2014 Non-polio AFP Rate* Percent Adequate Stool Specimen Collection ** Non-Polio AFP Rate < 1 1 1.99 >2 No Non-Polio AFP Case * Number of discarded AFP cases per 100,000 children under 15 years of age. ** Percentage with 2 specimens 24 hours apart and within 14 days of paralysis onset. Note: Some AFP cases may still be pending final classification. Total AFP Cases = 1477 Non-Polio AFP Rate =2.72 Adequate Stool specimen = 98% Districts reporting AFP cases= 64 (100%) Adequate Stool Specimen Collection < 60% 60% 79% > 80% No AFP Case 12
Non-polio AFP Cases by Month of Onset Bangladesh, 2010-2014 Month 2010 2011 2012 2013 2014 Jan 114 130 122 155 73 Feb 91 109 112 110 69 Mar 118 105 135 107 115 Apr 143 127 168 125 130 May 153 155 140 148 169 Jun 165 151 145 149 196 Jul 182 183 146 134 152 Aug 156 159 114 116 167 Sep 111 154 153 125 116 Oct 133 142 128 95 102 Nov 97 92 120 94 102 Dec 74 103 84 54 78 Total 1537 1610 1567 1412 1469 13
Non-polio AFP Rate* Surveillance Indicators by Province Indonesia, 2014 Non-Polio AFP Rate < 1 1 1.99 >2 No Non-Polio AFP Case Percent Adequate Stool Specimen Collection ** Total AFP Cases = 1732 Non-Polio AFP Rate = 2.25 Adequate Stool specimen = 90% Provinces reporting AFP cases= 34 (100%) Adequate Stool Specimen Collection < 60% 60% 79% > 80% No AFP Case * Number of discarded AFP cases per 100,000 children under 15 years of age ** Percentage with 2 specimens 24 hours apart and within 14 days of paralysis onset. Note: Some AFP cases may still be pending final classification. 14
Non-polio AFP Cases by Month of Onset Indonesia, 2010-2014 Month 2010 2011 2012 2013 2014 Jan 124 118 164 169 127 Feb 140 125 160 181 138 Mar 142 160 174 174 195 Apr 139 153 200 195 179 May 195 130 203 163 165 Jun 185 140 164 144 148 Jul 129 160 200 166 60 Aug 131 114 129 131 80 Sep 89 137 139 205 144 Oct 139 178 147 182 154 Nov 110 171 114 158 146 Dec 118 134 157 94 99 Total 1641 1720 1951 1962 1635 15
Annualized Non-polio AFP Rate* Surveillance Indicators by Province Thailand, 2014 Percent Adequate Stool Specimen Collection ** Non-Polio AFP Rate < 1 1 1.99 >2 No Non-Polio AFP Case Total AFP Cases = 237 Non-Polio AFP Rate = 1.87 Adequate Stool specimen = 80% Provinces reporting AFP cases= 65 (84%) Adequate Stool Specimen Collection < 60% 60% 79% > 80% No AFP Case * Number of discarded AFP cases per 100,000 children under 15 years of age ** Percentage with 2 specimens 24 hours apart and within 14 days of paralysis onset. Note: Some AFP cases may still be pending final classification. 16
Non-polio AFP Cases by Month of Onset Thailand, 2010-2014 Month 2010 2011 2012 2013 2014 Jan 21 17 22 19 24 Feb 13 18 24 20 25 Mar 14 13 25 24 12 Apr 12 13 7 22 16 May 28 26 20 19 17 Jun 25 17 15 17 18 Jul 33 26 30 27 27 Aug 23 22 30 19 18 Sep 43 24 30 18 11 Oct 16 27 37 16 16 Nov 22 22 27 18 19 Dec 22 24 22 16 22 Total 272 249 289 235 225 17
# Cases # Deaths # Tested for serology # Measles +ve # Rubella +ve # Outbreaks # Outbreaks Investigated # Cases # Deaths # Outbreaks # Cases # Outbreaks # Cases # Outbreaks # Cases Neonatal Tetanus Diphtheria Pertussis Encephalitis Number of Cases of AEFI 2 Date of last report # reports expected % Completeness % Timeliness VPD Reporting, 2014 Routine Reporting of clinically suspected measles cases Suspected measles outbreaks Laboratory Confirmed 1 Number of Cases Country Measles Outbreaks Rubella Outbreaks Mixed Outbreaks Bangladesh 1668 0 1607 97 176 71 71 1368 0 9 177 11 166 2 31 99 13 12 NR 3471 15-Feb-15 12 100 100 Bhutan 70 0 57 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 35 18 12-Jan-15 12 75 75 DPR Korea 11 0 11 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13-Mar-14 12 8 8 India NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR 12 0 0 Indonesia 10679 7 4636 1196 524 173 107 2104 21 77 737 7 69 3 13 70 394 NR NR NR 17-Feb-15 12 83 17 Maldives 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 15-Jan-15 12 42 25 Myanmar 242 0 242 8 24 7 7 236 0 3 102 1 5 0 0 32 35 3 0 0 13-Feb-15 12 83 75 Nepal 350 1 292 9 14 2 2 18 0 0 0 0 0 0 0 7 NR NR 1423 19 12-Feb-15 12 100 75 Sri Lanka 3113 0 2123 1560 10 1 1 10 0 0 0 1 10 0 0 0 0 80 191 6848 16-Feb-15 12 100 100 Thailand 1191 0 427 70 19 0 0 0 0 0 0 0 0 0 0 2 17 14 589 NR 22-Jan-15 12 83 25 Timor-Leste 47 1 40 25 1 2 2 33 1 2 20 0 0 0 0 1 2 3 6 3 23-Jan-15 12 8 0 Total 17371 9 9444 2965 772 256 190 3769 22 91 1036 20 250 5 44 211 461 112 2244 10362 1 At least 5 blood samples should be collected and tested from each outbreak. 2 Adverse Events Follow ing Immunization; Sri Lanka AEFI data do not reflect cases but events. 3 Monthly VPD and AEFI reports due to SEARO/IVD on or before 15th of each month. NR=No report Data as of 31 January 2015
# Cases # Deaths # Tested for serology # Measles +ve # Rubella +ve # Outbreaks # Outbreaks Investigated # Cases # Deaths # Outbreaks # Cases # Outbreaks # Cases # Outbreaks # Cases Neonatal Tetanus Diphtheria Pertussis Encephalitis Number of Cases of AEFI 2 Date of last report # reports expected % Completeness % Timeliness VPD Reporting, 2015 Routine Reporting of clinically suspected measles cases Suspected measles outbreaks Laboratory Confirmed 1 Number of Cases Country Measles Outbreaks Rubella Outbreaks Mixed Outbreaks Bangladesh 115 0 110 6 5 1 1 12 0 0 0 0 0 0 0 3 0 0 NR 71 15-Feb-15 1 100 100 Bhutan NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR 1 0 0 DPR Korea NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR 1 0 0 India NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR 1 0 0 Indonesia 256 1 59 12 1 0 0 0 0 0 0 0 0 0 0 2 0 17-Feb-15 1 100 0 Maldives 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15-Feb-15 1 100 100 Myanmar 23 0 23 0 6 0 0 0 0 0 0 0 0 0 0 1 1 0 0 13-Feb-15 1 100 100 Nepal 7 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 42 1 12-Feb-15 1 100 100 Sri Lanka 139 0 95 80 0 0 0 0 0 0 0 0 0 0 0 0 0 9 16 66 16-Feb-15 1 100 100 Thailand NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR 1 0 0 Timor-Leste NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR 1 0 0 Total 542 1 292 98 12 1 1 12 0 0 0 0 0 0 0 6 1 9 58 138 1 At least 5 blood samples should be collected and tested from each outbreak. 2 Adverse Events Follow ing Immunization; Sri Lanka AEFI data do not reflect cases but events. 3 Monthly VPD and AEFI reports due to SEARO/IVD on or before 15th of each month. NR=No report Data as of 31 January 2015
Measles and Rubella Serology (IgM), 2014 # % # % Bangladesh Dhaka 2051 1992 143 7.2 221 12.0 99.6 Bhutan Thimphu 69 61 0 0.0 4 6.6 77.0 DPR Korea Pyongyang 55 55 2 3.6 0 0.0 100.0 India India Total Indonesia Indonesia Total Ahmedabad 468 468 306 65.4 25 15.4 99.6 Bengaluru 528 381 258 67.7 27 22.0 93.7 Bhopal 212 212 134 63.2 21 26.9 63.7 Chennai 796 263 150 57.0 20 17.7 86.7 Guw ahati 74 74 28 37.8 32 69.6 95.9 Hyderabad 138 138 103 74.6 3 8.6 95.7 Jaipur 289 289 205 70.9 17 20.2 95.2 Kolkata 1386 1386 752 54.3 281 44.3 0.0 Lucknow 683 623 496 79.6 15 11.8 62.8 Patna 171 171 117 68.4 11 20.4 66.7 Pune 889 869 570 65.6 38 12.7 91.6 5634 4874 3119 64.0 490 27.9 60.8 Bandung 902 902 369 40.9 231 43.3 96.1 Jakarta 4083 4027 1558 38.7 531 21.5 65.7 Surabaya 2860 2857 1718 60.1 189 16.6 44.5 Yogyakarta 2643 2643 661 25.0 394 19.9 58.3 10488 10429 4306 41.3 1345 22.0 60.6 Maldives Male 695 695 0 0.0 3 0.4 100.0 Myanmar Yangon 282 282 24 8.5 29 11.2 83.3 Nepal Kathmandu 328 328 8 2.4 15 4.7 97.3 Sri Lanka Colombo 2080 2054 1496 72.8 10 1.8 86.8 Thailand Bangkok 147 147 12 8.2 8 5.9 100.0 Timor-Leste Dilli NR NR NR NR NR NR NR TOTAL Country Laboratories Source: Reported by SEAR Measles Laboratory Netw ork 1 To be reported w ithin 4 days in 2014 - in transition state Number of Serum Samples Received Number Tested 21829 20917 9110 43.6 2125 18.0 69.6 NR=No Report Measles +ve Results Rubella +ve % Results Reported w ithin 7 Days 1 Data as of 31 January 2015
Measles and Rubella Serology (IgM), 2015 # % # % Bangladesh Dhaka 110 110 7 6.4 5 4.9 100.0 Bhutan Thimphu NR NR NR NR NR NR NR DPR Korea Pyongyang NR NR NR NR NR NR NR India Indonesia Indonesia Total Ahmedabad 36 36 25 69.4 4 36.4 100.0 Bengaluru 48 35 20 57.1 8 53.3 100.0 Bhopal 5 5 5 100.0 0 NR 100.0 Chennai 63 16 11 68.8 0 0.0 93.8 Delhi 57 57 44 77.2 1 7.7 59.6 Guw ahati 5 5 4 80.0 0 0.0 100.0 Hyderabad 6 6 2 33.3 0 0.0 100.0 Jaipur 24 24 22 91.7 0 0.0 100.0 Kolkata 91 91 78 85.7 4 30.8 100.0 Lucknow 279 258 201 77.9 6 10.5 20.5 Patna 41 41 31 75.6 3 30.0 97.6 Pune NR NR NR NR NR NR NR 655 574 443 77.2 26 19.8 59.9 Bandung 93 93 33 35.5 36 60.0 86.0 Jakarta 236 236 56 23.7 61 33.9 92.4 Surabaya 159 159 60 37.7 21 21.2 100.0 Yogyakarta 162 162 16 9.9 31 21.2 0.0 650 650 165 25.4 149 30.7 70.3 Maldives Male 2 2 0 0.0 0 0.0 100.0 Myanmar Yangon 43 43 2 4.7 9 22.0 100.0 Nepal Kathmandu 16 16 1 6.3 2 13.3 100.0 Sri Lanka Colombo 95 95 80 84.2 0 0.0 91.6 Thailand Bangkok 4 4 0 0.0 0 0.0 100.0 Timor-Leste Dilli NR NR NR NR NR NR NR TOTAL Country India Total Laboratories Source: Reported by SEAR Measles Laboratory Netw ork 1 To be reported w ithin 4 days from 2014 - in transition state Number of Serum Samples Received Number Tested 1575 1494 698 46.7 191 24.0 71.2 NR=No Report Measles +ve Results Rubella +ve % Measles Results Reported w ithin 4 Days 1 Data as of 31 January 2015