Case Discussion Starring Melissa Ladrech as Sara Bonjovi and Michael Kozart as Dr. Keigh Directed by Carlos Mariscal

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Michael Kennedy, MFT Division Director Case Discussion Starring Melissa Ladrech as Sara Bonjovi and Michael Kozart as Dr. Keigh Directed by Carlos Mariscal Michael Kozart, MD, PhD Medical Director, Sonoma County Behavioral Health

This is a fictitious story based on made-up characters. Any resemblance to living people, current or historical, is entirely coincidental and unintended.

Simulated Case: Chapter 1

Discussion Overview Young adult woman presents with symptoms of depression: Topics for Discussion Primary vs. Secondary Depression Medication vs. Counseling

8 different Primary Depressive Disorders Major Depressive D/O Disruptive Mood Dysregulation D/O Persistent Depressive D/O (Dysthymia) Premenstrual Dysphoric D/O Substance/Mediation-Induced Depressive D/O Depressive D/O due to a Another Medical Condition Other Specified Depressive D/O Unspecified Depressive D/O Depression can also be a secondary characteristic of every diagnosis in the DSM.

Major Depressive Disorder (F32-F33) 5 or more of the following 9 (Criteria A) symptoms, each persisting for 2 wks. or more: Depressed mood Markedly diminished interest or pleasure in most activities Significant weight loss or gain (up to 5% of baseline weight) Sleep disturbance: insomnia or hypersomnia Energy disturbance: psychomotor agitation or retardation Fatigue Feelings of worthlessness, guilt Diminished ability to concentrate, make decisions Recurrent thoughts of death, Suicidal Ideation

Major Depressive Disorder, Continued. Specific Qualifiers in the DSM (p. 184-188) Melancholic, Anxious, Mixed (hyponmanic/manic), Atypical, Psychotic, Seasonal Melancholic Features ( pseudo-dementia picture) Somewhat equivalent to the antiquated endogenous depression category from the DSM-II. Extreme loss of pleasure and reactivity Diurnal variation (worse in AM) Marked psychomotor retardation or agitation Significant weight change Overwhelming sense of Guilt Probably the most responsive to AD treatment (indeed the prototype condition for all early AD efficacy studies).

15% lifetime prevalence 10% incidence in primary care populations Women are twice as likely as men to develop MDD Mean age of onset is between ages 40-50 but can arise at all age ranges. Lifetime risk of suicide for all pts. with MDD is 2.2-15% <25% of all MDD pts. meet the criteria for MDD with melancholic features. Untreated, typical Major Depressive episode last 6-13 mo 5-10% of everyone who develops MDD later go on to develop BPAD. (Kaplan and Sadock, Synopsis of Psychiatry):

Do we feel at this stage that the case is appropriate to be managed by PCP, or should we seek out BH consultation? What about the role of medication vs. counseling? Should the PCP be doing something different? Is the medication approach to depression the most inclusive framework?

Simulated Case: Chapter 2

Discussion Overview The focus of the case has now shifted to the management chronic pain and opiate dependency: Topics for Discussion; At what point do we cross the line from chronic pain diagnosis to a Substance Use disorder? What do we mean by co-occurring disorder? Maintenance/Harm Reduction vs. Tapering and Discontinuation

Definition of SUD: Criteria A: Problematic substance use leading to clinically significant impairment or distress as manifested by at least two of following within a 12 month period. Drugs taken in larger amounts for longer periods than indicated Desire to cut down, but unable to do so Trying to obtain drugs at the expense of other daily activities Craving/urge to use Social/occupational impairment Use that results in physically hazardous situations Persistent use despite knowledge of detriments Tolerance Withdrawal symptoms

Dual Diagnosis does not exist in the DSM, but SAMSHA does refer to Co-Occurring Disorders. The concept is challenging: Are we talking about two or more independent or two mutuallydependent disorders. (Opiate Use Disorder, Depression, Pain). Conceptually, what are the benefits of addressing these disorders as discrete/different entities versus as one whole entity?

Is the focus on Pain legitimate, or should we be collapsing that into the focus on a substance use disorder, or should we be dealing with both simultaneously? Has pain become a smoke-screen for the underlying depression and/or substance use disorder?

Simulated Case: Chapter 3

Discussion Overview We now learn that there are deeper psychological themes that may be driving the depression and the substance use disorder. Topics for discussion: Personality Disorder vs. Personality Profile How might we reformulate the case around Obsessive- Compulsive traits? A counseling approach

Prior to DSM 5, personality was coded on Axis II. In DSM 5, there is no distinction between Axis I and II. Personality defined: Enduring patterns of perceiving, relating to, and thinking about the environment and oneself that are exhibited in a wide range of social and personal contexts. Only when personality traits are inflexible and maladaptive and cause significant functional impairment or subjective distress do they constitute personality disorders. (DSM 5, p. 647).

Three Clusters of Personality Cluster A: Paranoid, Schizoid, Schizotypal Cluster B: Antisocial, Borderline, Narcissistic Cluster C: Avoidant, Dependent, Obsessive-Compulsive Personality Disorder Qualitatively Distinct Syndrome. DSM 5 recognizes 9 different specific syndromes as outlined above. An enduring pattern of inner experience and behavior that deviates markedly from the expectations of the individual s culture. Personality Profile An evaluation of personality that rests on a continuum between normal and maladaptive. Traits are identified, measured, and clumped into a general profile, but they do not necessarily constitute a disorder. DSM 5 recognizes 6 such profiles: Antisocial, Avoidant, Borderline, Narcissistic, Obsessive-Compulsive, and Schizotypal.

Obsessive-Compulsive Profile: Self-identity defined in relation to work or productivity Difficulty completing tasks or realizing goals, associated with rigid and unreasonably high standards So caught up in internal world, has difficulty identify with others. Perceived lack of empathy Relationships sacrificed for work goals. Inflexibility Restricted emotional expression The line between Profile and Disorder is one of degree or intensity

Arguably, Sara s mental distress is driven by her marked Obsessive- Compulsive personality traits, suggesting that counseling rather than medication might be more valuable. Most substance use reflects a self-medicating process. Individuals treat uncomfortable emotions, thoughts, or impulsive behaviors with a numbing/calming/uplifting drug. There is no way to get at the core of the substance use disorder without identifying what they are trying to medicate. By this definition, Substance Use is a manifestation of an underlying other disorder. In the case of Sara, the other disorder could well involve her O-C personality traits. Consider the Dynamic/Cognitive approach (as opposed to the static approach).

One dynamic/cognitive approach is to identify a core vulnerability. In many Obsessive-Compulsive individuals, lack of trust in one s own judgement or ability lies at the heart of the problem. With our Cognitive Behavioral Model, we can try to key into a key thought that exerts a negative influence over other feelings, behaviors and physical symptoms.

The Five Areas of the Cognitive Behavioral Model (CBM)

Core Thought: I do not know enough to make a rational decision about whether I ve put in enough effort whether my work job is complete whether I ve meet expectations for better or for worse whether I can overlook certain imperfections or risks whether I can say this is the best it s going to get whether I can turn my back on a potential threat and move on. These core thoughts lead to corresponding reactions: Feelings: anxious, worried, overwhelmed, Behavior: frozen, rigid, perfectionistic Physical Symptoms: tired, tense Reciprocal Effects: Feelings, Behaviors and Symptoms magnify the thought that one is truly lacking in some ability or skill to be the person you want to be. This further erodes trust in self, leading to more self-defeating thoughts.

Psychological Antidotes: Focus on correcting core thoughts through rational persuasion, insight. Offer alternative thinking systems. Explain how errant thoughts came to be. Focus of relaxation to address anxiety, fear, worry Behavioral exercises to test out new possibilities

Valuable counseling breakthroughs can occur in a 15 minute, primary care visit, providing the case formulation is accurate, and efficient therapeutic skills are utilized. BH consultation can aid in this process: the warm-hand off can flow both ways!!!! Become like water, my friend, Bruce Lee.