INTER-AMERICAN DRUG ABUSE CONTROL COMMISSION C I C A D

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INTER-AMERICAN DRUG ABUSE CONTROL COMMISSION C I C A D SIXTY-THIRD REGULAR SESSION April 25-27, 2018 México D.F., México OEA/Ser.L/XIV.2.63 CICAD/doc.2385/18 25 April 2018 Original: English THE OPIOID CRISIS IN CANADA 1

The Opioid Crisis in Canada Federal Approach to a National Public Health Crisis CICAD 63 April 2018

Summary To provide an overview of the opioid crisis in Canada To highlight key federal actions to address the opioid crisis To highlight federal priorities for action 3

What are Opioids? Opioids Opioids are drugs with pain relieving properties that are used primarily to treat pain. Prescribed medications: fentanyl, morphine, oxycodone, hydromorphone, medical heroin Produced or obtained illegally Opioids can also induce euphoria (feeling high), creating potential for them to be used improperly. Problematic opioid use Problematic use of opioids can occur in multiple ways such as: Using an opioid medication that was not prescribed for you Taking an opioid medication improperly (taking more, wrong time) Taking illegally produced or obtained opioid Opioid Use Disorder Opioid use disorder changes the brain making it hard to stop using. 4

Substance use has long been a reality Problematic Substance Use Medical Use Occasional Drug Use But circumstances have changed fundamentally 5

Prescription opioid use in Canada has been increasing, and the illegal drug supply has become contaminated 1. High rates of opioid prescribing Canada is the second highest per capita consumer of opioids among all countries In 2016, more than 20 million prescriptions for opioids were dispensed A recent CIHI report suggested that overall quantity of opioids dispensed in Canada declined between 2012 and 2016. However, the proportion of people prescribed strong opioids remained steady 2. Emergence of strong synthetic opioids (e.g., fentanyl, carfentanil)* in illegal drug supply In Canada, the percentage of deaths involving fentanyl or fentanyl analogues was 74% from January to June 2017 (compared to 53% in 2016) Fentanyl was detected in 82% of illegal drugrelated deaths in BC between January and October 2017 Illicit Drug Overdose Deaths Including and Excluding Fentanyl in British Columbia * fentanyl ~100 times stronger than morphine * carfentanil ~10,000 times stronger than morphine Source: BC Centre for Disease Control 6

This has resulted in Canada s Opioid Crisis There were 2,861 apparent opioid-related deaths in Canada in 2016 The number of opioid-related deaths are expected to exceed 4,000 in 2017 7

The initial spike in deaths first manifested in Vancouver, but has rapidly migrated to many parts of BC Evolution of the Number of Illicit Drug-Related Deaths in British Columbia 2010 2015 Source: BC Centre for Disease Control 8

The initial spike in deaths first manifested in Vancouver, but has rapidly migrated to many parts of BC 2016 2017 f f = forecasted Source: BC Centre for Disease Control 9

Number of Opioid-Related Deaths A similar rise in opioid-related deaths is now also evident in other regions of Canada such as Ontario 1400 Opioid-related deaths in Ontario: 2003 to 2017 1200 Major spike in past year 1000 800 600 400 200 0 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017f f = forecasted (based on number of opioid-related deaths in May-July 2017) Source: Public Health Ontario 10

Municipal-level data are more limited, but what s available clearly show all income levels and neighborhoods affected Opioid-Related Deaths in the City of Calgary by Median Household Income of Neighbourhood (Jan - Sept 2017) Number of opioid-related deaths Source: Opioids and Substances of Misuse Alberta Report, 2017 Q3 (Alberta Health) 11

Death Rates per 100,000 population The sharp rise in opioid-related deaths has made it a leading cause of mortality among working-age Canadians Rates by Leading Cause of Deaths for Canadians Aged between 30 and 39 (2014) 25.0 22.2 20.0 15.0 17.8 15.2 13.4 13.1 10.0 5.6 5.0 0.0 1.9 1.9 1.4 f = forecasted (based on an estimated 4,000 opioid-related deaths in 2017) *Data on accidents and suicide may include opioid-related deaths Source: Statistics Canada AND National Report on Apparent Opioid-Related Deaths 12

Additional Context In BC and AB the majority of deaths were alone and were in private residences In BC, nearly 90 per cent of people who died were alone inside a home when they suffered an overdose In ON, over the past 5 months, opioid-related emergency department visits have almost doubled Source: Ontario Public Health Opioid Tracker While deaths are occurring in and around larger urban areas, many smaller communities are impacted as well Data from BC and AB indicated that First Nations communities are disproportionately affected 13

Addressing the crisis is a complex public health issue Adapted from: British Columbia Overdose Action Exchange Meeting Report, 2016 14

requiring a whole of society approach Federal Government Provinces and Territories International community Municipalities Other Stakeholders (e.g., NGOs, Industry) Whole of Society Approach to the Opioid Crisis Health System Providers Indigenous organizations / populations People with Lived and Living Experience First Responders / Law Enforcement 15

under leadership of the Minister of Health Ministerial Mandate Commitment Work closely with other orders of government, as well as substance use experts, service providers, first responders, law enforcement, and people with lived and living experience in order to ensure Canada s response to the current opioid crisis is robust, well-coordinated, and effective. We have responded through: significant new federal investments; enacting new legislation; and, fast-tracking regulatory action. The Government of Canada is coordinating a whole-of-government approach that is grounded in compassion and evidence. Source: Government of Canada Actions on Opioids 2016 and 2017 16

Federal Approach on Canada s Opioid Crisis PUBLIC HEALTH EMERGENCY RESPONSE Enabling a coordinated pan-canadian response to the opioid crisis Data, surveillance and research Public communications P/T and stakeholder engagement Surge capacity, mobilization and support PREVENTION TREATMENT HARM REDUCTION ENFORCEMENT Preventing problematic opioid use Implement the Health Portfolio s Problematic Prescription Drug Use Strategy Improve prescribing practices Better inform Canadians about the risks of opioids Supporting innovative approaches to treatments Better access for rural and remote First Nations communities Improve access to medication-assisted treatments for opioid use disorder Improve treatment options for pain management Share knowledge on treatments for opioid use disorder Increase cooperation between the criminal justice system and social services sector (e.g., Drug Treatment Courts) Supporting a range of tools and measures for individuals and communities Support the establishment of supervised consumption sites Facilitate access to naloxone Ensure timely laboratory drug analysis information is shared between partners Support legislation to protect individuals who seek emergency assistance for overdose Reduce public health consequences of problematic drug use Addressing illegal drug production, supply and distribution Continue enforcement on the importation, exportation and trafficking of illegal opioids Pursue legislative, regulatory, policy and programmatic changes to better control substances and equipment Collect, assess and share information with law enforcement agencies domestically and internationally Support education and training for law enforcement AN APPROACH SUPPORTED BY STRONG EVIDENCE Better identifying trends, targeting interventions, monitoring impacts and supporting evidence-based decisions Facilitate timely and comparable data collection and methodologies Consult experts and support research and knowledge sharing 17

PREVENTION Preventing problematic opioid use Updated guidelines for opioid prescribing Public information toolkit Outreach to festivals and universities 18

TREATMENT Supporting innovative approaches to treatments Supporting the development of national treatment guidelines Supporting drug treatment courts / collaborative approaches in provinces and territories Coverage for opioid agonist treatments in some First Nations and Inuit communities Consulting on barriers to prescribing and dispensing methadone Allowing the import of medications, not yet authorized in Canada, for urgent public health needs (e.g., Diaphin) 19

HARM REDUCTION Supporting a range of tools and measures for individuals and communities Making naloxone more widely available without a prescription Providing take home naloxone kits for people being released from prison Streamlined process for supervised consumption sites Temporary overdose prevention sites if province or territory indicate an urgent public health need Good Samaritan Overdose Act 20

ENFORCEMENT Addressing illegal drug production, supply and distribution RCMP national operational strategy for synthetic opioids Regulatory changes to control fentanyl precursors Legislative changes to control pill presses and new dangerous substances entering the illegal market Collaboration with China and other international partners to disrupt the import of illegally produced fentanyl Drug Analysis Service: Summary report of samples analysed Top 10 controlled substances identified in Canada from Jan 1 to June 30, 2017 21

EVIDENCE AN APPROACH SUPPORTED BY STRONG EVIDENCE National surveillance of apparent opioid-related deaths with provincial-territorial collaboration Dedicated field epidemiologists embedded in Provinces and Territories Research on interventions for preventing and treating problematic substance use Facilitating the translation of evidence into policies and practice Supporting innovative approaches and interventions through the Substance Use and Addictions Program (SUAP) 22

Moving Forward: Key Federal Priorities for Actions Increase access to treatment Explore removing regulatory barriers to treatment Support dissemination and implementation of National treatment guidelines Expand treatment options in First Nations and Inuit communities Support pilot projects on safer pharmaceutical alternatives to illegal drugs (e.g., hydromorphone) Provide emergency funding to provinces and territories for treatment services Support innovative approaches Authorize supervised consumption sites to offer drug checking services Support pilot projects to provide drug checking services Explore new ways in using and sharing data to help those on the front lines Work with provinces and territories to establish a streamlined protocol for temporary overdose prevention sites should the province or territory indicate urgent public health need Expand the Substance Use and Addictions Programs to fund innovative approaches to treatment and prevention Address stigma Engage people with lived and living experience Address stigma through awareness and training Fund peer-support pilot projects Make better linkages between social strategies and fair treatment for people who use drugs Launch a public education campaign 23