In the adult population, does the Spurlings sign/test have good sensitivity* and specificity** in detecting cervical radiculopthy?

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Specific Question: In the adult population, does the Spurlings sign/test have good sensitivity* and specificity** in detecting cervical radiculopthy? Clinical bottom line Two systematic reviews have demonstrated that the Spurlings sign/test has high specificity (94%) but low to moderate sensitivity in detecting adults with cervical radiculopathy. Therefore it is considered an important part of an examination of any patient with neck and arm pain. Why is this important? In patients who have neck and/or radiating arm pain, the Spurlings sign/test is used by clinicians to establish if the symptoms are arising from pressure on cervical nerves. It is important to evaluate if this test is reliable and sensitive in clinical practice. The Spurling sign/ test was originally described in 1944, it is a manoeuvre used to assess nerve root involvement (aka radicular pain). The original description of the test was: Manga et al 2003 in Rubenstein 2007 However according to Anekstein et al (2012) there have been at least 5 modifications described. A positive Spurling's sign/test is when the pain arising in the neck radiates in the direction of the corresponding dermatome ipsilaterally. It is a variant of the foraminal compression test (cervical compression test). Video of the spurlings test can be found at http://www.physio-pedia.com/spurling%27s_test

Search timeframe 2007-2017 Inclusion Criteria Population and Setting Intervention or Exposure Comparison, if any Outcomes of interest Types of studies Description Search terms (In the final document this should be a combination of your clinical and librarian search terms) Adults Radicular pain Cervical nerves Spurlings sign/test (also known as Maximal Cervical Compression Test and Foraminal Compression Test) Sensitivity Specificity Cohort study Rcts SRs Routine Databases Searched Clinical Knowledge Summaries, PEDro, BMJ Updates, Clinical Evidence, TRIP, Database, NICE, HTA, Bandolier, The Cochrane Library, Medline, Cinahl, Embase, PsycInfo, Professional websites. Joanna Briggs Institute, Web of science, Sports discus and Pub med Date of search- 3.2.17

Results of the search 2 Included studies 97 Unique studies downloaded 49 Potentially relevant 47 Excluded studies as Retrospective small studies or did not answer our CAT question Table 1- Detail of two included studies First Author, year and type of study Simpson et al 2006 Systematic review Population and setting Trials exploring accuracy of spinal orthopaedic tests- Studies included if clear and reproducible description of the test was given Intervention or exposure tested Spinal orthopaedic tests Study results 21 studies, 7656 patients 5 papers looked at cervical tests- reasonable quality score (6-12, best score possible was 14) Heterogeneity of tests didn t allow pooling Spurlings sign/ test thought to have high specificity (94%) but was not sensitive Assessment of quality and comments Only English language 2 reviewers Used QUADAS quality score 2 papers considered to have low quality score Rubenstein et al 2007 Trials exploring clinical provocation tests of the Provocation tests of the neck for diagnosing 6 studies 713 patients 4 trials looked at Spurlings sign/test Good search including ref lists and authors

neck. Included trial if: Sensitivity and specificity included, compared against a reference standard,, any provocation tests diagnosis cervical radiculopathy cervical radiculopathy Spurlings demonstrated low to moderate sensitivity and high specificity 2 reviewers Used QUADAS quality score Very few primary care studies Substantial heterogeneity Summary The evidence from these two reviews is consistent in terms of the sensitivity and specificity of the Spurlings sign/test and due to this it would be considered as an important component of a physical examination of a patient presenting with neck and arm pain. However only one of the studies included evaluated these tests in primary care and this study was of poor quality. More research is required to evaluate this test in the primary care setting. Implications for Practice/research Spurlings sign/test would be considered to be an important component of a physical examination of a patient presenting with neck and arm pain What would you tweet? (140 characters) Spurlings sign/test- high specificity but low sensitivity but we should still use as part of our examination References Anekstein Y et al What is the best way to apply Sprurling s Test for cervical radiculopathy Clin Orthop Related Research 470:2566-2572

Simpson R and Gemmell H 2006 Accuracy of spinal orthopaedic tests: a systematic review Chroprcatic and Osteopathy 14:26 Rubenstien SM Pool JJM Tulder M van Riphagen II E de Vet H 2007 A systematic review of the diagnostic accuracy of provocative tests of the neck for diagnosing cervical radiculopathy European Spine Journal 16:307-319 *Sensitivity (also called the true positive rate, the recall, or probability of detection) measures the proportion of positives that are correctly identified as such (i.e. the percentage of sick people who are correctly identified as having the condition). **Specificity (also called the true negative rate) measures the proportion of negatives that are correctly identified as such (i.e., the percentage of healthy people who are correctly identified as not having the condition).