Intraoperative techniques for managing astigmatism

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I am a consultant for: Disclosure Intraoperative techniques for managing astigmatism Eric Donnenfeld, M.D. Clinical Professor of Ophthalmology NYU Trustee Dartmouth Medical School President ASCRS Acufocus Allergan Alcon AMO Aquesys Bausch & Lomb CRST Elenza Glaukos Kala Lacripen Lensx Mati Pharmaceuticals Merck Mimetogen Novabay Ocuhub Odyssey Pfizer PRN QLT RPS Sarcode Strathspey Crown Tearlab TearScience TLC Laser Centers TrueVision Wavetec Effects of misalignment 4 o : 14% 10 o : 34% 30 o : No Axis shifts! If > 30 o, astigmatism! Pre-op marking Goal is to provide reference marks to help with alignment intra-operatively Marking done with patient upright in pre-op area to minimize cyclorotation effects

Pre-op Marking Intraoperative Marking Wetfield Osher ThermoDot Marker bipolar mark, ink-free VERION Reference Unit and Digital Marker Imaging: keratometry, pupillometry, reference image (scleral vessels, limbus, iris features) Surgical planning: incision & implantation axis planning customization Akahoshi electronic toric marker beeps when aligned horizontally Guide: uses patient information and images for tracking overlay; accounts for cyclorotation, eliminates need for pre-op marking Limbal Relaxing Incisions Pros Inexpensive Easy to perform Minimal instrumentation Can be done at time of cataract surgery No impact on cataract healing Can be repeated Cons Must have topographer and be able to interpret topography May induce irregular astigmatism when greater than 1.5 D Risk of perforation Less precise than laser vision correction or toric IOLs

Nomograms Where Do You Place Your LRI During Cataract Surgery? Gills Koch Lindstrom Wallace Refractive axis Keratometric axis Topographic axis Thorton Nichamin Casebeer Donnenfeld Calculating Incision Induced Astigmatism Calculating LRI Incisions First step: Calculate surgically induced cylinder from incision RES11062SK 12

Getting Started with LRI s Getting Started with LRI s Step 1: Start in OR with a peribulbar block Step 2: Pre-set 0.6 mm depth diamond blade Step 3: Limbal relaxing incision ½ mm in from limbus. Step 4: Fixate globe with.12 forceps 180 degrees away from incision. Step 5: Use upside down topography and center incisions on steep axis (+cylinder). Step 6: Set diamond knife perpendicular in cornea, hold like a dart, allow blade to seat fully then pull slowly towards surgeon. Limbal Relaxing Incisions Challenges-Limbal Relaxing Incisions Variable and unpredictable treatment and response Imprecise depth, length, angulation and position of incision LRIs are an art form not a science

Femtosecond Laser Arc Incisions are Adjustable Full effect of the incision is not achieved until the incision is manually opened Intraoperatively or postop Titrate response to laser by adjusting Starting Laser Nomogram Donnenfeld Nomogram for Limbal Relaxing Incisions 0.50 D 1 Incision, 1 ½ Clock Hours (45 Deg. 0.75 D 2 Incisions, 1 Clock Hour (30 Deg. 1.50 D 2 Incisions, 2 Clock Hours (60 Deg. 3.00 D 2 Incision, 3 Clock Hours (90 Deg. Nomogram for 9 mm Arc Incisions 1 Incision, 1 Clock Hours (30 Deg. 2 Incisions, 2/3 Clock Hour (20 Deg. 2 Incisions, 1 1/3 Clock Hours (40 Deg. 2 Incision, 2 Clock Hours (60 Deg. Line separation Spot separation Energy Angulation of incision Intrastromal Ablations for Astigmatism *Use 5 degrees more for against-the-ruleastigmatism *Use 5 degrees more for younger patients *Use 5 degrees less for older patients 85% Depth Less effective than full thickness incisions Smaller optical zones Bowman s membrane remains intact Less pain Reduced loss of corneal sensation Less dry eye Greater wound stability No need for antibiotics LRI Inexpensive Can be combined with advantages of femtosecond laser cataract surgery Best for 1 D or less cylnder LRIs vs Toric IOLs Toric IOLs Does not induce irregular astigmatism Can be used in thin mildly irregular corneas Does not induce dry eye Best for 1.5 D or more cylinder

Conclusions LRIs, arcuate incisions, and toric IOLs are now playing an increasingly important role in refractive cataract surgery Femtosecond arcuate incisions may now be made at the time of cataract surgery with increased precision and safety Intrastromal arcuate incisions will play an important role in astigmatism management Toric IOLs are best for higher levels of cylinder