Tolfenpyrad A new broad spectrum insecticide from Nichino America

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Tolfenpyrad A new broad spectrum insecticide from Nichino America IR-4 FOOD USE WORKSHOP SEPT 2010 Las Vegas, NV

2010 IR 4 Food Use Workshop Las Vegas, NV Nichino America Inc. Jim Adams, Manager, Product Development Marie Maks Regulatory Affairs Manager Phone: (302) 636 9001 Web site: www.nichino.net

Chemical Details on Tolfenpyrad Chemical Name: 4 chloro 3 ethyl 1 methyl N y [4 p tolyloxy)benzyl] pyrazole 5 carboxamide Empirical Formula: C 21 H 22 Cl N 3 O 2 Molecular Weight: 283.9 Code Number: NAI 2302

Insects / Diseases Controlled Hemiptera, Coleoptera, Diptera, Lepidoptera, Thysanoptera, Orthoptera and Acarina Poisoning i by ingestion; contact tactivity; it antifeeding activity against leps Powdery Mildews (MOA unknown) Target Crops: Vegetables, Cucurbits, Cole Crops Fruits & Nuts Selected row crops Ornamentals

Efficacy Trials Use rate 0.137 to 0.274 lb. a.i/acre (153 307 grams ai / hectare) 14 27 oz/a (15% EC and 15% SC formulations) Alternative mode of action useful against numerous vegetable and fruit/nut pests

Coleoptera: Efficacy Trials Colorado Potato Beetle, Plum Curculio, Japanese Beetle, Flea Beetle Lepidoptera: Grape Berry Moth, Helicopverpa spp., Diamonback Moth, Imported Cabbage Worm, Leafrollers Hemiptera; Aphid, Psyllids (include. ACP and Pear Psylla), Hoppers, Mealybugs (including Vine Mealybug) Thysanoptera: Tobacco Thrips, citrus Thrips, Onion Thrips, W. Flower Thrips Diptera: CherryFruitfly Fruitfly, Apple Maggot, Blueberry Maggot Other: Katydid, Rust Mites, Citricola Scale

Efficacy Trials Powdery Mildews: Lettuce Cucurbits Hops Possibly certain downy mildew species and Albugo (white rust)

U.S. Registration Timeline Greenhouse registration summer 2010 (reduced risk) Submit crop uses with residue chemistry data fall 2010 as reduced risk candidate Anticipated food tolerances 2012

EC Vs. SC Efficacy on Colorado Potato Beetle Miller Research, Rupert, ID 2008 a a a cd cde bc de f b b NAI-2302 SC: 14 fl oz (153 g ai/ha); 18.1 fl oz (197 g ai/ha) NAI-2302 EC: 14 fl oz (153 g ai/ha); 18.1 fl oz (197 g ai/ha) Leverage (imidacloprid + cyfluthrin) 3.75 fl oz/a (88.7 g ai/ha) Applications made: 17 July 2008, 13.3 GPA

1 application 1 application Spray Volume: 96 GPA Grape leafhopper: Erythroneura elegantula and Variegated LeafHopper: Erythroneura variabilis in Grape

Thrips: Thrips tabaci in Cotton

Control of Plum Curculio on Apple Michigan State Univ. 2009 Applied PF, PF+14 and PF+28

c b b b Application: 100 GPA Timing: Each flight for total of 3/season Harvest: 17 August 0.25% NIS in all treatments P= 0.05 Duncan s New MRT

a b Application: Petal fall Spray Volume: 200 GPA P=0.05 Duncan s New MRT Harvest Evaluation: October 5 th Light scarred Heavy scarred

Hachi Katydid Efficacy Cage Study in Nectarine Parlier, CA Walt Bentley UC IPM 2009 Treatment Rate/Acre 1 DAT 3 DAT 4 DAT 7 DAT 14 DAT Imidan 70WP 4 lb 94 100 100 100 100 Altacor 1.6 oz 92 100 100 100 100 Delegate WG 6 oz 88 88 88 94 94 Avaunt 6 oz 69 81 81 81 94 Voliam Flexi 7 oz 38 38 44 56 81 Hachi 15EC 14 oz 94 94 94 94 94 Hachi 15EC 21 oz 100 100 100 100 100 Untreated 0 0 0 0 0 Application: Hand sprayed Katydids: 3-4 instars (4katydids/cage) Spray volume: 136 GPA No statistics yet

Questions?