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Transcription:

- ( ) - * :... (MDR) (ESBLs: Extended-Spectrum Beta Lactamases). :.. (CLSI:Clinical and Laboratory Standards Institute). ESBL. combined disk method ESBL : / / / / / B / ( /). / / combined disk method. ( ). ( ) ESBL ( ). B :. ESBL. ESBLs : // : -// : * E-mail: bzamanzad@yahoo.com

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/. :.. ( ) B.. References: 1.Yan JJ, Tsai SH, Chuang CL, et al. OXA-type beta-lactamases among extended-spectrum cephalosporin-resistant Pseudomonas aeruginosa isolates in a university hospital in southern Taiwan. J Microbiol Immunol Infect 2006; 39: 130-4. 2.S Shenoy, S Baliga, DR Saldanha, et al. Antibiotic sensitivity patterns of Pseudomonas aeruginosa strains isolated from various clinical specimens. Indian J Med Sci 2002; 56: 427-30. 3.Pirnay J, De Vos D, Cochez C, et al. Molecular epidemiology of Pseudomonas aeruginosa colonization in a burn unit: Persistence of a multidrug-resistant clone and a silver sulfadiazine-resistant clone. J Clin Microbiol 2003; 41: 1192-202. 4.Chanawong A, M zali FH, Heritage J, et al. SHV-12, SHV-5, SHV-2a and VEB-1 extended-spectrum β- lactamases in Gramnegative bacteria isolated in a university hospital in Thailand. J Antimicrob Chemother 2001; 48: 839-52. 5.Prinsloo A, van Straten AMS, Weldhagen GF. Antibiotic synergy profiles of multidrugresistant Pseudomonas aeruginosa in a nosocomial environment. South Afr J Epidemiol Infect 2008; 23: 7-9. 6.Bonfiglio G, Carciotto V, Russo G, et al. Antibiotic resistance in Pseudomonas aeruginosa: an Italian survey. J Antimicrob Chemother 1998; 41: 307-10. 7.Geha DJ, Uhl JR, Gustaferro CA, et al. Multiplex PCR for Identification of Methicilin-Reesistant Staphylococci in the Clinical Laboratory. J Clin Microbiol 1994; 32: 1768-72. 8.Knothe H, Shah P, Krcmery V, et al. Trasferable resistance to cefotaxime, cefoxitin, cefamandole and cefuroxime in clinical isolates of klebsiella pneumoniae and serratia marcescense. Infection 1983; 11: 315-7. 9.Vahdat K, Rezaie R, Gharibi O. Bacteriology of hospital-acquired infection and antibiotic resistance in a hospital university of Bushehr Port "Fatemeh Zahra (s)" in 2002-2003. Iran South Med J 2005; 7: 135-40. 10.Lee S, Park YJ, Kim M, et al. Prevalence of Ambler class A and D ß-lactamases among clinical isolates of Pseudomonas aeruginosa in Korea. J Antimicrob Chemother 2005; 56: 122-7. 11.Strateva T, Ouzounova-Raykova V, Markova B, et al. Problematic clinical isolates of Pseudomonas aeruginosa from the university hospitals in Sofia, Bulgaria: current status of antimicrobial resistance and prevailing resistance mechanisms. J Med Microbiol 2007; 56: 956-63. 12.Cavallo JD, Fabre R, Leblanc F, et al. Antibiotic susceptibility and mechanism of B- lactam resistance in 1310 strain of Pseudomonas aeruginosa: a French multicentre study (1996). J Antimicrob Chemother 2000; 46:133-6. 13.Mirsalehian A, Feizabadi M, Akbari Nakhjavani F, et al. Prevalence of extended spectrum beta lactamases among strains of Pseudomonas aeruginosa isolated from burn patients (Persian). Tehran Uni Med J 2008; 66: 333-7. 14.Carmeli Y, Troillet N, Eliopoulos GM et al. Emergence of antibiotic-resistant Pseudomonas aeruginosa: comparison of risks associated with different antipseudomonal agents. Antimicrob Agents Chemother 1999; 43, 1379-82. 15.Srikumar R, Kon T, Gotoh N et al. Expression of Pseudomonas aeruginosa multidrug Efflux Pumps MexA-MexB-OprM and MexC-MexD-OprJ in a multidrugsensitive Escherichia coli starin. Antimicrob Agents Chemother 1998; 42, 65-71.