ADULT RETROGRADE INTUSSUSCEPTION Brian Tiu Richmond University Medical Center September 3, 2015

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ADULT RETROGRADE INTUSSUSCEPTION Brian Tiu Richmond University Medical Center September 3, 2015

CASE PRESENTATION 41 yo woman presented one day hx abdominal pain, worsening nausea/vomiting denied flatus/bm two days s/p laparoscopic leiomyomectomy, POD#2

CASE PRESENTATION PMHx: fibroids PSHx: RYGB surgery 1999, panniculectomy, plastic surgery for excess skin Medications: multivitamin NKDA 5 pack year smoking history

CASE PRESENTATION T98.4, BP150/85, P88, R18, O2 sat 99% midline scar, dressings over lap port sites, no erythema, tender mostly at RLQ/suprapubic area CBC 5.9 > 13.1/40.1 < 298; 81% granulocytes BMP 139 / 3.5 / 108 / 24 / 9 / 0.5 < 77 Ca 7.2 UA negative

OR exploratory laparotomy - previous midline scar mild lysis of adhesions 20 cm segment retrograde jejunal intussusception 20 cm from R&Y anastomosis reduced, no lead point found ran the small bowel: anastomosis cecum

POST-OP COURSE Admitted to the floor POD#1 - passed trial of void POD#2 - return of bowel function, tolerated clear liquid diet POD#3 - regular diet, d/c home POD#6 - clinic visit, no issues

OUTLINE pathophysiology diagnosis treatment retrograde intussusception

EPIDEMIOLOGY adult intussusception - only 5% of all cases 1-5% of intestinal obstructions in adults

TYPES enteric ileocolic/ileocecal colonic

bowel telescopes into an adjacent segment obstruction and ischemia to the intussuscepting segment 90% associated with pathologic processes Tumors act as the lead point in >65% of adult

SIGNS & SYMPTOMS mechanical obstruction - pain, nausea/vomiting, distention, obstipation strangulation - peritonitis, UOP, fever, tachycardia K, Cr, leukocytosis, lactic acidosis

RADIOLOGY plain film sonography CT scan

ULTRASOUN D target sign

CT SCAN target sign

SURGERY peritoneal hemodynamic instability ischemia/necrosis long length, wide diameter of the intussusception presence of a lead point - high incidence of tumor no role for air/contrast enema

EN BLOC RESECTION high incidence of underlying malignancy inability to differentiate malignant vs benign pre- or intra-operatively theoretical risk of intra-luminal seeding, venous embolization anastomotic complications

RETROGRADE INTUSSUSCEPTION association with gastric bypass surgery largest case series: 23 (10 years, >15,000 patients) proximal end acts as the intussuscipiens distal end is the intussuseptum

HOW CAN WE RESOLVE No lead point THIS? Roux stasis syndrome ectopic pacemakers waves collide in jejunum retrograde peristalsis

FINDINGS

CONCLUSIONS OF THE STUDY? Resection and reconstruction of the involved anastomosis uncut Roux-en-Y early surgery for peritonitis or obstruction recurrence can occur regardless of intervention

SUMMARY intussusception represents a small percentage of patients presenting with SBO surgery indicated peritonitis, hemodynamic instability, ischemia/necrosis, long length/wide diameter of the intussusception, lead point suspect retrograde intussusception with RYGB

Marinas, A. et al. Intussusception of the bowel in adults: A review. World Journal of Gastroenterology. Jan 2009. 15(4): 407-411 Simeone, DM. et al. Chapter 48. Ileus and Bowel Obstruction. Greenfield s Surgery: Scientific Principles and Practice - 5th Ed. Philadelphia, PA. Lippincott Williams & Wilkins. 2011 Simper, SC. et al. Retrograde (reverse) jejunal intussusception might not be such a rare problem: a single group s experience of 23 cases. Surgery for Obesity and Related Diseases. 2008. (4) 77 83 Rea, JD. et al. Approach to Management of Intussusception in Adults: A New Paradigm in the Computed Tomography Era. Nov 2007. (73): 1098-1105 Yakan, S. et al. Intussusception in adults: Clinical characteristics, diagnosis and operative strategies. World Journal of Gastroenterology. Apr 2009. 15(16): 1985-1989