Coronary artery surgery results In The Survey Committee of Japanese Association for Coronary Artery Surgery (JACAS)

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Coronary artery surgery results In 2017 The Survey Committee of Japanese Association for Coronary Artery Surgery (JACAS)

Coronary artery bypass grafting (CABG), 2017 Total cases : 12,584 Isolated CABG : 8,497 (68%)(previous year:67%) Concomitant CABG : 4,087 (32%)(previous year:33%) Isolated CABG Initial elective : 7,144 Except initial elective :1,353 Off-pump : 4,562 Off-pump : 646 On-pump : 2,582 On-pump : 707 (Off-pump rate : 64%) (Off-pump rate : 48%) (previous year : 62%) (previous year : 51%)

% Changes of off-pump CABG rate(initial elective CABG) 80 70 64% 60 50 40 30 20 10 0 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 year

Initial elective CABG :7,144(100%) On-pump (arrest) :1,516(21.2%) On-pump (beating) :1,066(14.9%) Off-pump (total) :4,562(63.9%) Off-pump (complete) :4,431 On-pump (conversion) : 131 Off-pump complete rate :97.1% Off to on-pump conversion rate :2.9% (previous year:2.3%)

Mortality of isolated CABG :1.52% (previous year:1.66%) Mortality of initial elective CABG:0.81% (previous year:1.09%) On-pump (arrest) :0.73% On-pump (beating):1.59% Off-pump (total) :0.65% Off-pump (complete):0.61% (previous year:0.86%) On-pump (conversion):2.29% (previous year:5.88%)

mortality (%) Changes of mortality (Isolated and initial elective CABG) 4 3.5 Isolated CABG 3 2.5 2 1.52% 1.5 1 0.5 0 0.81% 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 year

mortality(%) Changes of mortality for procedures(initial elective CABG) 8 7 6 Off-pump(complete) On-pump(beating) On-pump(arrest) Off to on-pump(conversion) 5 4 3 2 1 0 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 year

Mortality according to number of diseased vessels (Initial elective CABG:7,144, mortality:0.81%) mortality (%) 2.0 1VD (1.26%) LMT+1VD (0.59%) LMT+2VD (1.15%) LMT (0%) 1.0 0 2VD (0.44%) 3VD LMT+3VD (0.76%) (1.07%) 25 50 75 100 (%)

Mortality according to number of diseased vessels (Except initial elective CABG:1,353, mortality:5.25%) mortality 10 (%) 1VD (6.98%) LMT (5.66%) LMT+1VD (1.96%) 5 2VD (4.03%) 3VD (5.56%) LMT+2VD (4.79%) LMT+3VD (5.54%) 0 25 50 75 100 (%)

Mortality according to surgical procedures (Except initial elective CABG:1,353, mortality:5.25%) mortality (%) 10 5 0 Off-pump (total) 3.09% On-pump (beating) 9.63% On-pump (arrest) 3.32% 25 50 75 100 (%)

Graft number according to procedures(initial elective CABG) graft number average No. (previous year) Total 1 2 3 4 2.99 (3.05) On-pump (arrest) 1 2 3 4 3.13 (3.17) On-pump (beating) 1 2 3 4 3.03 (3.10) Off to on (conversion) 1 2 3 4 2.98 (3.25) Off-pump (complete) 1 2 3 4 2.94 (2.99) 0 25 50 75 100%

Procedure according to graft number(initial elective CABG) graft number 1 Off to on-pump (conversion) Off-pump On-pump (beating) On-pump (arrest) 2 Off-pump On-pump (arrest) 3 Off-pump On-pump (arrest) 4 Off-pump On-pump (arrest) 62.3% 0 25 50 75 100%

On-pump (arrest) vs. off-pump (Initial elective CABG) bypass+ bypass On-pump (arrest) Off-pump RCA 64% 71% On-pump (arrest) Off-pump LAD 92% 93% On-pump (arrest) Off-pump LCX 71% 81% 0 25 50 75 100%

Off-pump vs. off to on-pump conversion (Initial elective CABG) Bypass No. Off to on-pump conversion conversion rate RCA(+) 2,908 LAD(+) 4,241 LCX(+) 3,254 Off-pump Off-pump Off-pump 2.7% 2.4% 2.7% RCA( ) 1,654 LAD( ) 321 LCX( ) 1,308 Off-pump Off-pump Off-pump 3.1% 9.3% 3.2% 0 25 50 75 100%

Age distribution according to gender (Initial elective CABG) Male:79.3% 635 (Age) 80 Female:20.7% 300 2214 1881 70 79 60 69 411 665 796 50 59 91 (case) 336 49 62 (case) 3000 2000 1000 0 0 1000

% Changes of elderly cases(initial elective CABG) 60 51.6% 50 40 30 70 y.o. 80 y.o. 20 10 12.7% 0 2000 2001 2002 2003 2004 2005 2006 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 year

mortality (%) Changes of mortality according age(initial elective CABG) 3.5 3 49 y.o. 50-59 y.o. 60-69 y.o. 2.5 2 70-79 y.o. 80 y.o. 1.5 1 0.5 0 2000 2001 2002 2003 2004 2005 2006 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 year

Graft selection (Total graft number of isolated CABG:22,293) SVG (40.9%) LITA (35.7%) RITA (15.8%) RA (3.7%) GEA (3.5%)

% Changes of graft selection 45 40 35 30 25 20 15 LITA RITA GEA RA SVG 10 5 0 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 year

% Stroke rate according to procedures(isolated CABG) Stroke cases:97 Stroke rate:97/8497(isolated CABG)=1.14% 3 2.5 2 1.5 p:0.1402 p:0.4548 p:0.835 p:0.0058 p:0.2131 p:0.4229 1.86% 1.34% 2.53% 1 0.5 0.81% 0 Off-pump (complete) On-pump(arrest) On-pump(beating) Off to on-pump (coversion)

Results of emergency CABG after PCI complications Emergency CABG; operation after PCI complications (coronary occlusion and/or bleeding), within 24 hours Cases:75 Rate:75/8497(isolated CABG);0.88% Death cases:11 Mortality:14.67% Results cases death cases mortality(%) CABG1 25 4 16.00 CABG2 26 3 11.54 CABG3 11 1 9.09 CABG4 8 2 25.00 Other procedures 5 1 20.00

mortality (%) Changes in results of ventricular septal perforation 60 50 40 30 20 10 0 year Total No.:172, death:40 (mortality:23.2%)

Results of ventricular septal perforation (1) alive death Total cases 132 40 172(mortality;23.2%) Bypass(+) 70 14 84 (mortality;16.6%) Bypass( ) 82 26 108 (mortality;24.0%) (case) 0 50 100 150 200

Results of ventricular septal perforation (2) Anterior infarction(mortality;21.2%) alive death Patch closure 32 10 42 (mortality;23.8%) Infarction exclusion Others 10 47 93 14 61 (mortality;22.9%) 10 (mortality;0%) Post-inferior infarction(mortality;27.1%) Patch closure 29 10 39 (mortality;25.6%) Infarction exclusion 6 6 12 (mortality;50.0%) Others 8 8(mortality;0%) 0 50 100 150 (case)

mortality (%) Changes in results of ventricular septal perforation according to infarction region 70 60 Anterior VSP 50 Post-inferior VSP 40 30 20 10 0 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 year

mortality (%) Changes in results of papillary muscle rupture 50 45 40 35 30 25 20 15 10 5 0 year Total No.:68, death:13 (mortality:19.1%)

Results of papillary muscle rupture alive death Total cases 55 13 68 (mortality:19.1%) Bypass(+) 41 3 44(mortality;6.8%) Bypass( ) 14 10 24 (mortality;41.6%) 0 20 40 60 (case)

mortality (%) Changes in results of LV free wall rupture 120 100 80 60 40 20 0 year Total No.:131, death:46 (mortality:35.1%)

Results of LV free wall rupture alive death Total cases 85 46 Blowout type 14 28 42 (mortality;66.6%) 131(mortality;35.1%) Bypass(+) Bypass( ) 2 4 12 6(mortality;66.6%) 24 36 (mortality;66.6%) Oozing type 71 18 89(mortality;20.2%) Bypass(+) Bypass( ) 18 1 19 (mortality;5.2%) 53 17 70 (mortality;24.3%) 0 50 100 150 (case)

mortality (%) 80 Changes in results of LV free wall rupture according to rupture type 70 60 50 40 Blowout type 30 Oozing type 20 10 0 2009 2010 2011 2012 2013 2014 2015 2016 2017 year

mortality (%) Changes in results of left ventricular aneurysm (LVA) 18 16 14 12 10 8 6 4 2 0 year Total No.:170, death:9 (mortality:5.29%)

Results of left ventriculoplasty and/or aneurysmectomy alive Total cases 161 9 170 death (mortality;5.29%) Bypass(+) 115 5 120(mortality;4.16%) Bypass( ) 46 4 50 (mortality;8.00%) 0 100 200 300 (case)

Results of MVR or MVP for ischemic MR Total cases 340 alive death 16 356 (mortality;4.49%) Mitral valve plasty Total Bypass(+) 271 251 233 11 11 262(mortality;4.19%) 244(mortality;4.51%) Bypass( ) 18 18(mortality;0%) Mitral valve replacement Total Bypass(+) 63 89 5 5 94(mortality;5.31%) 68(mortality;7.35%) Bypass( ) 26 26(mortality;0%) 0 50 100 150 200 250 300 (case)

Results of ischemic MR+LVA or ischemic cardiomyopathy alive death Total cases 49 4 53 (mortality;7.54%) Left ventriculoptasty + Mitral valve plasty Total Bypass(+) 26 36 3 3 39(mortality;7.69%) 29(mortality;10.34%) Left ventriculoptasty + Mitral valve replacement Bypass( ) Total Bypass(+) Bypass( ) 5 10 13 8 10(mortality;0%) 1 1 14(mortality;7.14%) 9(mortality;11.11%) 5(mortality;0%) 0 25 50 75 (case)

Conclusions (1) 1. The mortality of isolated CABG was 1.52%, that of initial elective CABG was 0.81%, indicating better excellent results than those of previous year. 2. Of initial elective CABGs, 64% cases underwent off-pump procedure, showing still high rate. The mortality of off-pump was 0.61%, which was much lower than that of previous year, indicating excellent results. 3. Off to on-pump conversion rate was 2.9%, and the mortality of those cases was 2.29%, which was remarkable better results than that of previous year. 4. Of all 4 and/more bypass procedures, 62.3% cases were done by off-pump CABG. 5. CABG cases is getting older year by year, more than 70 years old patients rate was 51.6%, more than 80 was 12.7%, showing high rate.

Conclusions (2) 6. Arterial grafts were used in 58.8%n of all grafts, while vein grafts were used in 40.9%. The frequency of vein graft usage increased in recent years. 7. The complication rate of central nerve system stroke of all isolated CABG was 1.14%. This rate of off-pump CABG showed significantly lower than those of on-pump (beating), which means that OPCAG can avoid this complication. 8. After PCI complications, emergency operation underwent in 0.88% of all isolated CABG within 24 hours. The mortality of those cases was 14.67%, showing still high rate. 9. The results of complications for acute and old myocardial infarction got worse than those of previous year. Especially, the mortality of post-inferior VSP and blowout type free wall rupture, were high rate, indicating poor prognosis.