Pick Paterson 1944

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383 33 1 1 28 4 383 391 2008 Key Words reduplicative paramnesia geographical mislocation double orientation identity right frontal lobe reduplicative paramnesia Pick 1901 1903 2 Ruff 1981 Staton 1982 Patterson 1985 1989 Alexander 1979 Moser 1998 1993 Kapur 1988 Trillet 1988 Budson 2000 Feinberg 1989 Murai 1997 Pick 1901 1903 Paterson 1944 1 FK. 67 4 30 10 2002 11 23 67

34 384 28 4 11 26 CT 148/94 74/ 36.8 170cm 53kg Japan Coma Scale 1 Glasgow Coma Scale E4 M6 V4 Babinski Gegenhalten 10 FK FK 2 4 23 3 4 10 2 6 FK 10 13 8 FK 17 18 4 22 23 25 32 8 FK

385 35 33 34 8 34 FK E FK P E P E P 99 E P E P E? P E P E P 100 E P E P E P E P E P E 1 1 P FK FK FK FK 2 7 7 FK 1

36 386 28 4 1 2 1 1.5 28 42 6 2 1 1 1.5

387 37 WAIS R PIQ Rey Osterrieth Complex Figure Test ROCFT 1 2mm Rey Auditory Verbal Learning Test RAVLT ROCFT Wisconsin Card Sorting Test WCST 2 6 WAIS R PIQ BIT WMS R RAVLT WCST Word Fluency Design Fluency Modified Stroop Test Trail Making Test BADS self monitoring 45 MRI T2 Brodmann 9 46 4cm 99m Tc HMPAO SPECT RI 1 7 FK

38 388 28 4 Kapur 1988 1 2 FK FK 2 3 FK 4 FK FK

389 39 Paterson 1944 Paterson Paterson double orientation 2 spatial displacement 12 3 4 Paterson Pick 1903 1989 2 SPECT Brodmann area10 Burgess PW 2007 Brodmann area10 A gateway between mental life and the external world Brodmann area10 2 2 2 self awareness Cutting 1991 delusional misidentification syndromes identity self awareness Stuss 2001 self awareness 1 Alexander, M. P., Stuss, D. T. & Benson, D. F. Capgras syndrome A reduplicative phenomenon. Neurology, 29 334 339, 1979. 2 Budson, A. E., Roth, H. L., Rentz, D. M., et al. Disruption of the ventral visual stream in a case of reduplicative paramnesia. Ann. N. Y. Acad. Sci., 911 447 452, 2000. 3 Burgess, P. W., Gilbert, S. J. & Dumontheil, I. A gateway between mental life and the external

40 390 world Role of the rostral prefrontal cortex area 10. 23 8 26, 2007. 4 Cutting, J. Delusional misidentification and the role of the right hemisphere in the appreciation of identity. Br. J. Psychiatry, 159 suppl. 14 70 75, 1991. 5 Ellis, H. D. & Young, A. W. Accounting for delusional misidentifications. Br. J. Psychiatry, 157 239 248, 1990. 6 Feinberg, T. E. & Shapiro, R. M. Misidentification reduplication and the right hemisphere. Neuropsychiatry Neuropsychol. Behav. Neurol., 2 39 48, 1989. 7 Hakim, H., Verma, N. P. & Greiffenstein, M. F. Pathogenesis of reduplicative paramnesia. Journal of Neurology, Neurosurgery, and Psychiatry, 51 839 841, 1988. 8 1986, pp. 399 408. 9 1992, pp. 135 167. 10 1 52 1091 1096, 2000. 11 Kapur, N., Turner, A. & King, C. Reduplicative paramnesia possible anatomical and neuropsychological mechanisms. J. Neurol., Neurosurg. Psychiatry, 51 579 581, 1988. 12 Morin, A. Right hemispheric self awareness A critical assessment. Consciousness and Cognition, 11 396 401, 2002. 13 Moser, D. J., Cohen, R. A., Malloy, P. F., et al. Reduplicative paramnesia Longitudial neurobehavioral and neuroimaging Analysis. J. Geriatr. Psychiatry Neurol., 11 174 180, 1998. 14 Murai, T., Toichi, M., Sengoku, A., et al. Reduplicative paramnesia in patients with focal brain 28 4 damage. Neuropsychiatry Neuropsychol. Behavi. Neurol., 10 190 196, 1997. 15 32 1507 1512, 2003. 16 Paterson, A. & Zangwill, O. L. Recovery of spatial orientation in the post traumatic confusional state. Brain, 67 54 68, 1944. 17 Patterson, M. B. & Mack, J. L. Neuropsychological analysis of a case of reduplicative paramnesia. J. Clin. Exp. Neuropsychol., 7 111 121, 1985. 18 Pick, A. Über eine neuartige Form Von Paramnesie. Jahrbücher für Psychiatrie und Neurologie, 20 1 35, 1901. 19 Pick, A. Clinical studies.. On reduplicative paramnesia. Brain, 26 260 267, 1903. 20 Ruff, R. L. & Volpe, B. T. Environmental reduplication assosiciated with right frontal and parietal lobe injury. J. Neurol., Neurosurg. Psychiatry, 44 382 386, 1981. 21 Staton, R. D., Brumback, R. A. & Wilson, H. Reduplicative paramnesia A disconnection syndrome of memory. Cortex, 18 23 26, 1982. 22 Stuss, D. T., Picton, T. W. & Alexander, M. P. Consciousness, self awareness, and the frontal lobe. In The frontal lobes and neuropsychiatric illness ed. Salloway, S. P., Malloy, P. F. & Duffy, J. D.. American Psychiatric Publishing, Washington, 2001, pp. 101 109. 23 1989, pp. 59 71. 24 Trillet, M. C. & Laurent, B. Mémoire et Amnésies. Masson, Paris, 1988. 25 9 112 119, 1993.

391 41 Abstract From geographical mislocation and double disorientation to reduplicative paramnesia a neuropsychological study of a case with right frontal lobe hemorrhage Michitaka Funayama Motoichiro Kato Masaru Mimura In this study, we report a case FK with typical reduplicative paramnesia which developed after a circumscribed right frontal lobe hemorrhage. In this case, we were able to follow the clinical and neuropsychological courses of the development of reduplicative paramnesia in detail. The patient showed geographical mislocation of place and double orientation before the appearance of geographical reduplicative paramnesia in which he believed that more than two identical hospitals exist in the world. Given the clinical course of this case, it is possible that his reduplicative paramnesia did not result from visuospatial disorder and frontal executive dysfunction, but rather developed from deficits of self orientation to the outside world or environments. Dysfunction of the right dorsolateral prefrontal lobe could be considered to play a critical role as the lesion responsible for reduplicative paramnesia.