CHAPTER 1: SEXUALLY TRANSMITTED AND BLOODBORNE INFECTIONS

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CHAPTER : SEXUALLY TRANSMITTED AND BLOODBORNE INFECTIONS Highlights In Peel, the incidence of Acquired Immunodeficiency Syndrome (AIDS) has remained low (. to. cases per,) since the introduction of the anti-retroviral therapies in 996. Any variability from year to year may be due to the small number of cases. Chlamydia is the most commonly reported sexually transmitted infection in Peel. In Peel, the incidence of chlamydia increased by approximately 7% over an eight-year period (from per, in 996 to 7 per, in ). This increase is due in part to improved detection methods and case finding by physicians. The incidence of gonorrhea in Peel has remained stable over the past five-year period (approximately to cases per,). Persons aged to years have the highest incidence of chlamydia and gonorrhea, the two most common sexually transmitted infections in Peel. In Peel, the incidence of syphilis has increased considerably since. Twenty new cases were reported in Peel in, as compared to one to two cases per year reported from 999 to. A similar increase in syphilis cases has been observed in the Greater Toronto Area., In Peel, the incidence of hepatitis B has been low since 997 (approximately one case per, or less). The incidence of hepatitis B was highest among people aged to 9 years followed by those aged to 9 years, especially in men. The incidence of hepatitis C in Peel has decreased since 997. The incidence of hepatitis C is highest in males aged to 9 years and in females aged to 9 years. INTRODUCTION Sexually transmitted infections (STIs) and bloodborne infections are caused by a variety of bacteria and viruses found in blood and body fluids (semen, vaginal fluids and sometimes breast milk and saliva). In addition to being spread by sexual contact, STIs can also be spread by another route such as injection or a cut in the skin. STIs are rarely spread through such activities as touching, hugging, shaking hands or non-sexual kissing. Gonorrhea and chlamydia are almost exclusively sexually transmitted. Other diseases can also be spread through contaminated blood. For hepatitis C, blood is the main route of infection; for syphilis, sexual transmission is most frequent; while for Human Immunodeficiency Virus infection (HIV) and hepatitis B, both blood and sexual transmission are the primary routes of transmission. All these diseases may be

passed from mother to child during pregnancy or birth, often with severe consequences to the fetus or newborn.

HIV/AIDS Human Immunodeficiency Virus (HIV) is the virus that causes Acquired Immunodeficiency Syndrome (AIDS).,,6 The progression from HIV infection to the development of AIDS varies greatly from person to person and depends largely on the extent to which the immune system has been damaged. About half of the people with HIV will develop AIDS within ten years after becoming infected, but the introduction of powerful anti-retroviral therapies in 996 has dramatically increased the time between HIV infection and the development of AIDS.,7,8 Figure.: Incidence of AIDS, Region of Peel and Ontario, 99-8 7 6 Cases per,* 99 996 997 998 999 Peel......7..6.9.7 Ontario..7..8.6..... Peel Cases 9 8 7 7 8 * Crude rate per,. Ontario data are //. Public Health as of //. 986-, Provincial Health Extracted: //, Health Figure.: Incidence of AIDS by Age Group, Region of Peel, 99- Combined Average annual cases per, Source: Peel Data from RDIS, Peel Public Health, as of //....8... 986-, Provincial Health Extracted: //, Health Planning Branch, Ontario Ministry of Health and Long- Term Care. -9-9 -9-9 -9 6+ Age Group (s)

Figure.: Incidence of HIV Infection, Region of Peel, 99- Cases per, 8 7 6 99 996 997 998 999 Peel..8..6..6.... Peel Cases 9 9 6 6 Sources: Peel Data from RDIS, Peel Public Health, as of //. 986-, Provincial Health Extracted: //, Health Figure.: Incidence of HIV Infection by Age Group, Region of Peel, 99- Combined 9 8 7 6 Average annual cases per, 7..6..6.6.6 Sources: Peel Data from RDIS, Peel Public Health, as of //. 986-, Provincial Health Extracted: //, Health -9-9 -9-9 -9 6+ Age Group (s) 6

CHLAMYDIA Chlamydia, the most common sexually transmitted infection in Canada, is a bacterial infection caused by Chlamydia trachomatis. The most common symptoms are urinary pain and genital discharge. If left untreated, chlamydia can cause a chronic infection (pelvic inflammatory disease), infertility and tubal pregnancy. However, more than % of infected males and 7% of infected females have no symptoms and are unaware of their condition, making diagnosis and treatment of chlamydia difficult. 6,9 Figure.: Incidence of Chlamydia, Region of Peel and Ontario, 99-8 9 6 Cases per, 99 996 997 998 999 * Peel..9 7.... 8.9 8. 67. 7.8 Ontario 8..8.7....8 68.9 7. 8. Peel Cases 96 876 97 87 7 8 67 8 9 * Ontario data are using 99 (adjusted) Canadian //. Public Health as of //. 986-, Provincial Health Planning Database (PHPDB) Extracted: //, Health Planning Branch, Ontario Ministry of Health and Long- Term Care. Figure.6: Incidence of Chlamydia by Age Group and Sex, Region of Peel, 8 6 97.6. Male Female 676. 87.. 8.8 8.8.6.8.7 6.6 7. 9..9 - -9 - -9-9 -9 + Sources: Peel Data from RDIS, Peel Public Health, as of //. 986-, Provincial Health Extracted: //, Health Age Group (s) 7

GONORRHEA Gonorrhea is a bacterial infection caused by Neisseria gonorrhea. Gonorrhea is very similar to chlamydia in that it presents with symptoms of urinary pain, genital discharge and can cause long-term complications such as chronic infection, infertility and tubal pregnancy. Like chlamydia, gonorrhea can be asymptomatic and go undiagnosed. 6,, Figure.7: Incidence of Gonorrhea, Region of Peel and Ontario, 99 - Cases per, 99 996 997 998 999 * Peel..7. 6.7.8..7.9.. Ontario 9.. 8.7..6 6.8 7. 8...8 Peel Cases 8 9 8 8 6 * Ontario data are using 99 (adjusted) Canadian //. Public Health as of //. 986-, Provincial Health Extracted: //, Health Figure.8: Incidence of Gonorrhea by Age Group and Sex, Region of Peel, Cases per, 6. 9..8 69. 79.8 Male Female Source: Peel Data from RDIS, Peel Public Health, as of //. 986-, Provincial Health Extracted: //, Health Planning Brach, Ontario Ministry of Health and Long- Term Care...8 8. 6. 9.9. 7... - -9 - -9-9 -9 + Age Group (s) 8

SYPHILIS Syphilis is a complex sexually transmitted infection caused by the bacteria Treponema pallidum. Syphilis moves through five stages if left untreated and is infectious mostly during the early stages (less than one year after becoming infected). However, it is during the later stages of the disease that syphilis can do the most damage to the body, affecting the brain, blood vessels, the heart and bones. It can eventually lead to death. Like chlamydia and gonorrhea, syphilis can be asymptomatic and go undiagnosed. 6, Figure.9: Incidence of Syphilis (Infectious), Region of Peel and Ontario, 99- Cases per, * Ontario data are using 99 (adjusted) Canadian 99 996 997 998 999 * Peel.9........9.7 Ontario.6........6. Peel Cases 8 //. Public Health as of //. 986-, Provincial Health Extracted: //, Health Figure.: Incidence of Syphilis (Infectious) by Age Group and Sex, Region of Peel, 99- Combined Average annual cases per,. Male Source: Peel Data from RDIS, Peel Public Health, as of //........6...9..7 Female... 986-, Provincial Health Extracted: //, Health Planning Brach, Ontario Ministry of Health and Long- Term Care. - -9 - -9-9 -9-9 6+ Age Group (s) 9

HEPATITIS B Hepatitis B is a viral infection which attacks the liver. There is a wide spectrum of illness caused by hepatitis B, ranging from no symptoms, a mild non-specific illness (loss of appetite, nausea and tiredness), to severe liver involvement (jaundice yellow skin and eyes and liver failure). People can be chronically infected with hepatitis B, especially if the disease is acquired early in life. Long-term complications of hepatitis B infection include cirrhosis (liver scarring), liver cancer and liver failure. 6, Figure.: Incidence of Acute Hepatitis B, Region of Peel and Ontario, 99- Cases per, 99 996 997 998 999 * Peel.8.......9.7. Ontario.9..6....... Peel Cases 6 9 9 8 * Ontario data are using 99 (adjusted) Canadian //. Public Health as of //. 986-, Provincial Health Planning Database (PHPDB) Extracted: //, Health Planning Branch, Ontario Ministry of Health and Long-Term Care. Figure.: Incidence of Acute Hepatitis B by Age Group and Sex, Region of Peel, 99- Combined Average annual cases per,.9.9.......9.8.6.6.. - -9 - -9-9 -9 + Age Group (s) Sources: Peel data from RDIS, Peel Public Health, as of //. 986-, Provincial Health Planning Database (PHPDB) Extracted: //, Health Planning Brach, Ontario Ministry of Health and Long-Term Care.

HEPATITIS C Hepatitis C is a viral infection of the liver. The symptoms of hepatitis C are similar to hepatitis B (loss of appetite, nausea, tiredness and jaundice) but tend to be milder and more subtle. Most people diagnosed with hepatitis C are chronically infected. Complications of hepatitis C include cirrhosis (liver scarring), liver cancer and liver failure. 6, Reporting of hepatitis C became mandatory in 99. In Canada, injection drug use is the primary risk factor and has been documented in 6% of the newly infected cases reported between 999 and. Figure.: Incidence of Hepatitis C, Region of Peel and Ontario, 99- Cases per, 8 7 6 99 996 997 998 999 * Peel 6.6 9..7 9.8 8..8.7 6.8.6. Ontario 6. 67.9. 6.. 7....8 9.8 Peel Cases 9 68 77 9 * Ontario data are using 99 (adjusted) Canadian //. Public Health, as of //. 986-, Provincial Health Extracted: //, Health Figure.: Incidence of Hepatitis C by Age Group and Sex, Region of Peel, 99- Combined Average annual cases per, Male Female. 9. 6.. 9..9 7.7. 8.7. 8.8... - -9 - -9-9 -9 + Age Group (s) Sources: Peel Data from RDIS, Peel Public Health, as of //. 986-, Provincial Health Planning Database (PHPDB) Extracted: //, Health Planning Brach, Ontario Ministry of Health and Long-Term Care.